Somatic mutation load of estrogen receptor-positive breast tumors predicts overall survival: An analysis of genome sequence data

Breast Cancer Research and Treatment

Volumn 146, Issue 1, 2014, Pages 211-220

  Haricharan, Svasti ^a   Bainbridge, Matthew N ^b   Scheet, Paul ^a   Brown, Powel H ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Codified Genomics LLC ^*  (United States)

Author keywords

Breast cancer; DNA damage repair; Estrogen receptor; Mutation load

Indexed keywords

ESTROGEN RECEPTOR; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CANCER MORTALITY; CANCER PROGNOSIS; CANCER SURVIVAL; DNA DAMAGE; ESTROGEN RECEPTOR GENE; ESTROGEN RECEPTOR NEGATIVE BREAST CANCER; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC LOAD; GENOME ANALYSIS; HUMAN; MISMATCH REPAIR; OVERALL SURVIVAL; PHENOTYPE; PREDICTIVE VALUE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOMATIC MUTATION; SURVIVAL RATE; TUMOR GENE; AGED; BIOLOGY; BREAST TUMOR; CANCER STAGING; DNA REPAIR; FEMALE; GENETICS; GENOMICS; METASTASIS; MIDDLE AGED; MORTALITY; MUTATION; NUCLEIC ACID DATABASE; PATHOLOGY; PROCEDURES; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; TUMOR VOLUME;

ADULT; AGED; BIOMARKERS, TUMOR; BREAST NEOPLASMS; COMPUTATIONAL BIOLOGY; DATABASES, NUCLEIC ACID; DNA DAMAGE; DNA REPAIR; FEMALE; GENETIC ASSOCIATION STUDIES; GENOMICS; HUMANS; MIDDLE AGED; MUTATION; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RECEPTORS, ESTROGEN; TUMOR BURDEN;

EID: 84903704283     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-2991-x     Document Type: Article

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