Luteolin inhibits smooth muscle cell migration and proliferation by attenuating the production of Nox4, P-Akt and VEGF in endothelial cells

Current Pharmaceutical Biotechnology

Volumn 14, Issue 12, 2014, Pages 1009-1015

  Ding, Hong ^a   Li, Dongye ^a   Zhang, Yanbin ^a   Zhang, Tian ^a   Zhu, Hong ^a   Xu, Tongda ^a   Luo, Yuanyuan ^a   Wang, Cheng ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin II; Endothelial cells; Luteolin; Proliferation and migration; Smooth muscle cells; Vascular endothelial growth factor

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANGIOTENSIN II; BETA ACTIN; LUTEOLIN; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; VASCULOTROPIN; NOX4 PROTEIN, RAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, RAT; VASCULOTROPIN A;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY ASSAY; CONTROLLED STUDY; CYTOTOXICITY TEST; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; MTT ASSAY; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL MOTION; CELL SURVIVAL; COCULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANGIOTENSIN II; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; LUTEOLIN; MALE; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84903690035     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/1389201015666140113113843     Document Type: Article

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