Impact on mortality of the timing of renal replacement therapy in patients with severe acute kidney injury in septic shock: The IDEAL-ICU study (initiation of dialysis early versus delayed in the intensive care unit): Study protocol for a randomized controlled trial

Trials

Volumn 15, Issue 1, 2014, Pages

  Barbar, Saber D ^a   Binquet, Christine ^b   Monchi, Mehran ^c   Bruyère, Rémi ^d   Quenot, Jean Pierre ^d  

^a DEPARTMENT OF NEUROLOGY   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c centre hospitalier de Melun   (France)

^d HÔPITAL DU BOCAGE   (France)

Author keywords

Intensive care; Renal replacement therapy; Septic shock; Severe acute kidney injury

Indexed keywords

CITRIC ACID; CREATININE; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; NORADRENALIN;

ADULT; ANTICOAGULANT THERAPY; ARTICLE; ARTIFICIAL VENTILATION; ATRIOVENTRICULAR BLOCK; BLEEDING; BLOOD FLOW VELOCITY; CONTINUOUS HEMODIALYSIS; CONTINUOUS HEMOFILTRATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRITICALLY ILL PATIENT; EARLY INTERVENTION; EMERGENCY TREATMENT; ERYTHROCYTE TRANSFUSION; HEART ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HEMODIALYSIS; HOSPITAL DISCHARGE; HUMAN; HYPERKALEMIA; HYPOTENSION; INTENSIVE CARE UNIT; INTENTION TO TREAT ANALYSIS; KIDNEY FUNCTION; LENGTH OF STAY; LUNG EDEMA; MAJOR CLINICAL STUDY; METABOLIC ACIDOSIS; METABOLIC DISORDER; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PATIENT SAFETY; PROTOCOL COMPLIANCE; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RENAL REPLACEMENT THERAPY; SEPTIC SHOCK; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SEVERE RENAL IMPAIRMENT; THERAPY DELAY; TORSADE DES POINTES; TREATMENT DURATION; URINE VOLUME; ACUTE KIDNEY INJURY; ADVERSE EFFECTS; CLINICAL PROTOCOL; CLINICAL TRIAL; COMPARATIVE STUDY; FRANCE; KAPLAN MEIER METHOD; METHODOLOGY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; TIME; TIME TO TREATMENT; TREATMENT OUTCOME;

ACUTE KIDNEY INJURY; CLINICAL PROTOCOLS; FRANCE; HUMANS; INTENSIVE CARE UNITS; INTENTION TO TREAT ANALYSIS; KAPLAN-MEIER ESTIMATE; LENGTH OF STAY; PROPORTIONAL HAZARDS MODELS; QUALITY OF LIFE; RENAL REPLACEMENT THERAPY; RESEARCH DESIGN; RESPIRATION, ARTIFICIAL; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; TIME FACTORS; TIME-TO-TREATMENT; TREATMENT OUTCOME;

EID: 84903685866     PISSN: None     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/1745-6215-15-270     Document Type: Article

References (40)

1. Pavon A, Binquet C, Kara F, Martinet O, Ganster F, Navellou JC, Castelain V, Barraud D, Cousson J, Louis G, Perez P, Kuteifan K, Noirot A, Badie J, Mezher C, Lessire H, Quantin C, Abrahamowicz M, Quenot JP, . EPIdemiology of Septic Shock (EPISS) Study Group Profile of the risk of death after septic shock in the present era: an epidemiologic study. Crit Care Med 2013, 41:2600-2609. EPIdemiology of Septic Shock (EPISS) Study Group.
2. Quenot JP, Binquet C, Kara F, Martinet O, Ganster F, Navellou JC, Castelain V, Barraud D, Cousson J, Louis G, Perez P, Kuteifan K, Noirot A, Badie J, Mezher C, Lessire H, Pavon A. The epidemiology of septic shock in French intensive care units: the prospective multicenter cohort EPISS study. Crit Care 2013, 17:R65.
3. Schrier RW, Wang W. Acute renal failure and sepsis. N Engl J Med 2004, 351:159-169.
4. Bagshaw SM, George C, Bellomo R. Early acute kidney injury and sepsis: a multicentre evaluation. Crit Care 2008, 12:R47.
5. Palevsky PM, Zhang JH, O'Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P. Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 2008, 359:7-20.
6. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C, . Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 2005, 294:813-818. Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators.
7. Bagshaw SM, Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten HM, Ronco C, Kellum JA, . Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes. Clin J Am Soc Nephrol 2007, 2:431-439. Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators.
8. Langenberg C, Wan L, Egi M, May CN, Bellomo R. Renal blood flow and function during recovery from experimental septic acute kidney injury. Intensive Care Med 2007, 33:1614-1618.
9. Cooper BA, Branley P, Bulfone L, Collins JF, Craig JC, Fraenkel MB, Harris A, Johnson DW, Kesselhut J, Li JJ, Luxton G, Pilmore A, Tiller DJ, Harris DC, Pollock CA. A randomized, controlled trial of early versus late initiation of dialysis. N Engl J Med 2010, 363:609-619.
10. Clark E, Wald R, Levin A, Bouchard J, Adhikari NK, Hladunewich M, Richardson RM, James MT, Walsh MW, House AA, Moist L, Stollery DE, Burns KE, Friedrich JO, Barton J, Lafrance JP, Pannu N, Bagshaw SM, . Canadian Acute Kidney Injury (CANAKI) Investigators Timing the initiation of renal replacement therapy for acute kidney injury in Canadian intensive care units: a multicentre observational study. Can J Anaesth 2012, 59:861-870. Canadian Acute Kidney Injury (CANAKI) Investigators.
11. Thakar CV, Rousseau J, Leonard AC. Timing of dialysis initiation in AKI in ICU: international survey. Crit Care 2012, 16:R237.
12. Bagshaw SM, Lapinsky S, Dial S, Arabi Y, Dodek P, Wood G, Ellis P, Guzman J, Marshall J, Parrillo JE, Skrobik Y, Kumar A, . Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy. Intensive Care Med 2009, 35:871-881. Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group.
13. Teschan PE, Baxter CR, O'Brien TF, Freyhof JN, Hall WH. Prophylactic hemodialysis in the treatment of acute renal failure. Ann Intern Med 1960, 53:992-1016.
14. Bouman CS, Oudemans-Van Straaten HM, Tijssen JG, Zandstra DF, Kesecioglu J. Effects of early high-volume continuous venovenous hemofiltration on survival and recovery of renal function in intensive care patients with acute renal failure: a prospective, randomized trial. Crit Care Med 2002, 30:2205-2211.
15. Elahi MM, Lim MY, Joseph RN, Dhannapuneni RR, Spyt TJ. Early hemofiltration improves survival in post-cardiotomy patients with acute renal failure. Eur J CardiothoracSurg 2004, 26:1027-1031.
16. Gettings LG, Reynolds HN, Scalea T. Outcome in post-traumatic acute renal failure when continuous renal replacement therapy is applied early vs. late. Intensive Care Med 1999, 25:805-813.
17. Liu KD, Himmelfarb J, Paganini E, Ikizler TA, Soroko SH, Mehta RL, Chertow GM. Timing of initiation of dialysis in critically ill patients with acute kidney injury. Clin J Am SocNephrol 2006, 1:915-919.
18. Seabra VF, Balk EM, Liangos O, Sosa MA, Cendoroglo M, Jaber BL. Timing of renal replacement therapy initiation in acute renal failure: a meta-analysis. Am J Kidney Dis 2008, 52:272-284.
19. Bagshaw SM, Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten HM, Ronco C, Kellum JA, . Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injury. J Crit Care 2009, 24:129-140. Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators.
20. Payen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E. Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial. Crit Care Med 2009, 37:803-810.
21. Piccinni P, Dan M, Barbacini S, Carraro R, Lieta E, Marafon S, Zamperetti N, Brendolan A, D'Intini V, Tetta C, Bellomo R, Ronco C. Early isovolaemic haemofiltration in oliguric patients with septic shock. Intensive Care Med 2006, 32:80-86.
22. Shiao CC, Ko WJ, Wu VC, Huang TM, Lai CF, Lin YF, Chao CT, Chu TS, Tsai HB, Wu PC, Young GH, Kao TW, Huang JW, Chen YM, Lin SL, Wu MS, Tsai PR, Wu KD, Wang MJ, . National Taiwan University Hospital Study Group on Acute Renal Failure (NSARF) U-curve association between timing of renal replacement therapy initiation and in-hospital mortality in postoperative acute kidney injury. PLoS One 2012, 7:e42952. National Taiwan University Hospital Study Group on Acute Renal Failure (NSARF).
23. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004, 8:R204-R212.
24. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R, . Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 2013, 39:165-228. Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup.
25. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G. SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference. Crit Care Med 2001, 2003(31):1250-1256.
26. Mehta RL, McDonald B, Gabbai FB, Pahl M, Pascual MT, Farkas A, Kaplan RM. A randomized clinical trial of continuous versus intermittent dialysis for acute renal failure. Kidney Int 2001, 60:1154-1163.
27. Vinsonneau C, Camus C, Combes A, de Costa Beauregard MA, Klouche K, Boulain T, Pallot JL, Chiche JD, Taupin P, Landais P, Dhainaut JF. Continuous venovenoushaemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentrerandomised trial. Lancet 2006, 368:379-385.
28. Brochard L, Abroug F, Brenner M, Broccard AF, Danner RL, Ferrer M, Laghi F, Magder S, Papazian L, Pelosi P, Polderman KH. An official ATS/ERS/ESICM/SCCM/SRLF statement: prevention and management of acute renal failure in the ICU patient: an international consensus conference in intensive care medicine. Am J RespirCrit Care Med 2010, 181:1128-1155.
29. Disease K, . Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group KDIGO clinical practice guideline for acute kidney injury. Kidney Int 2012, 2(Suppl):1-138. Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group.
30. Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med 2001, 33:337-343.
31. Abrahamowicz M, MacKenzie TA. Joint estimation of time-dependent and non-linear effects of continuous covariates on survival. Stat Med 2007, 26:392-408.
32. Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer 1976, 34:585-612.
33. Lopes JA, Fernandes P, Jorge S, Goncalves S, Alvarez A, CostaeSilva Z, Franca C, Prata MM. Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the acute kidney injury network classifications. Crit Care 2008, 12:R110.
34. Kellum JA, Levin N, Bouman C, Lameire N. Developing a consensus classification system for acute renal failure. Curr Opin Crit Care 2002, 8:509-514.
35. Ostermann M, Chang RW. Acute kidney injury in the intensive care unit according to RIFLE. Crit Care Med 2007, 35:1837-1843.
36. Thakar CV, Christianson A, Freyberg R, Almenoff P, Render ML. Incidence and outcomes of acute kidney injury in intensive care units: a veterans administration study. Crit Care Med 2009, 37:2552-2558.
37. Bagshaw SM, George C, Dinu I, Bellomo R. A multi-centre evaluation of the RIFLE criteria for early acute kidney injury in critically ill patients. Nephrol Dial Transplant 2008, 23:1203-1210.
38. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A. Acute kidney injury network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007, 11:R31.
39. Bagshaw SM, George C, Bellomo R. A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients. Nephrol Dial Transplant 2008, 23:1569-1574.
40. Joannidis M, Metnitz B, Bauer P, Schusterschitz N, Moreno R, Druml W, Metnitz PG. Acute kidney injury in critically ill patients classified by AKIN versus RIFLE using the SAPS 3 database. Intensive Care Med 2009, 35:1692-1702.