Heterogeneous phenotypes of acute respiratory distress syndrome after major trauma

Annals of the American Thoracic Society

Volumn 11, Issue 5, 2014, Pages 728-736

  Reilly, John P ^a,b   Bellamy, Scarlett ^b   Shashaty, Michael G S ^a,b   Gallop, Robert ^b   Meyer, Nuala J ^a   Lanken, Paul N ^a   Kaplan, Sandra ^a   Holena, Daniel N ^a   May, Addison K ^c   Ware, Lorraine B ^c,d   Christie, Jason D ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Center for Clinical Epidemiology and Biostatistics   (United States)

^c Department of Surgery Perelman School of Medicine University of Pennsylvania ^*  (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute respiratory distress syndrome; Critical illness; Hemorrhagic shock; Phenotype; Trauma

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ANGIOPOIETIN 2;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AFRICAN AMERICAN; ARTICLE; BLOOD TRANSFUSION; CAUCASIAN; COHORT ANALYSIS; CONSTRUCT VALIDITY; CRITICALLY ILL PATIENT; DISCRIMINANT VALIDITY; ERYTHROCYTE TRANSFUSION; FEMALE; HUMAN; INJURY SCALE; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; PATIENT TRANSPORT; PHENOTYPE; PROTEIN BLOOD LEVEL; RISK FACTOR; SYSTOLIC BLOOD PRESSURE; THORAX INJURY; THORAX RADIOGRAPHY; COMPLICATION; CRITICAL ILLNESS; FOLLOW UP; GENETICS; MIDDLE AGED; RESPIRATORY DISTRESS SYNDROME, ADULT; RETROSPECTIVE STUDY; THORACIC INJURIES; YOUNG ADULT;

ADULT; CRITICAL ILLNESS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; RESPIRATORY DISTRESS SYNDROME, ADULT; RETROSPECTIVE STUDIES; THORACIC INJURIES; TRAUMA SEVERITY INDICES; YOUNG ADULT;

EID: 84903575388     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201308-280OC     Document Type: Article

References (48)

1. Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD. Incidence and outcomes of acute lung injury. N Engl J Med 2005;353:1685-1693.
2. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R. The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149:818-824.
3. Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS; ARDS Definition Task Force. Acute respiratory distress syndrome: the Berlin definition. JAMA 2012;307:2526-2533.
4. Estenssoro E, Dubin A, Laffaire E, Canales H, Sáenz G, Moseinco M, Pozo M, Gómez A, Baredes N, Jannello G, et al. Incidence, clinical course, and outcome in 217 patients with acute respiratory distress syndrome. Crit Care Med 2002;30:2450-2456.
5. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000;342:1334-1349.
6. Gattinoni L, Pelosi P, Suter PM, Pedoto A, Vercesi P, Lissoni A. Acute respiratory distress syndrome caused by pulmonary and extrapulmonary disease: different syndromes? Am J Respir Crit Care Med 1998;158:3-11.
7. Calfee CS, Eisner MD, Ware LB, Thompson BT, Parsons PE, Wheeler AP, Korpak A, Matthay MA; Acute Respiratory Distress Syndrome Network, National Heart, Lung, and Blood Institute. Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med 2007;35: 2243-2250.
8. Walker L, Eiseman B. The changing pattern of post-traumatic respiratory distress syndrome. Ann Surg 1975;181:693-697.
9. Croce MA, Fabian TC, Davis KA, Gavin TJ. Early and late acute respiratory distress syndrome: two distinct clinical entities. J Trauma 1999;46:361-366, discussion 366-368.
10. Plurad D, Martin M, Green D, Salim A, Inaba K, Belzberg H, Demetriades D, Rhee P. The decreasing incidence of late posttraumatic acute respiratory distress syndrome: the potential role of lung protective ventilation and conservative transfusion practice. J Trauma 2007;63:1-7, discussion 8.
11. Dicker RA, Morabito DJ, Pittet JF, Campbell AR, Mackersie RC. Acute respiratory distress syndrome criteria in trauma patients: why the definitions do not work. J Trauma 2004;57:522-526, discussion 526-528.
12. Green TC, Black R, Grimes Serrano JM, Budman SH, Butler SF. Typologies of prescription opioid use in a large sample of adults assessed for substance abuse treatment. PLoS One 2011;6:e27244.
13. Spycher BD, Silverman M, Brooke AM, Minder CE, Kuehni CE. Distinguishing phenotypes of childhood wheeze and cough using latent class analysis. Eur Respir J 2008;31:974-981.
14. Savenije OE, Granell R, Caudri D, Koppelman GH, Smit HA, Wijga A, de Jongste JC, Brunekreef B, Sterne JA, Postma DS, et al. Comparison of childhood wheezing phenotypes in 2 birth cohorts: ALSPAC and PIAMA. J Allergy Clin Immunol 2011;127:1505-1512.e14.
15. Shah RJ, Diamond JM, Cantu E, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Bhorade S, et al. Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation. Chest 2013;144:616-622.
16. Reilly JP, Bellamy S, Shashaty MGS, Localio AR, Gallop R, Meyer NJ, Kaplan S, Holena D, Lanken PN, Christie JD. Early hypotension, severity of thoracic trauma, and blood transfusion are associated with an early endophenotype of acute lung injury after major trauma [abstract]. Am J Respir Crit Care Med 2012;185:A1161.
17. Reilly J, Bellamy S, Shashaty M, Meyer N, Holena D, May A, Ware L, Christie J. Timing of onset phenotypes of the acute respiratory distress syndrome (ARDS) after severe trauma. Abstract presented at the 42nd Critical Care Congress, January 19-23, 2013, San Juan, Puerto Rico. Crit Care Med 2012;40(12, Suppl 1):1-328.
18. Shah CV, Localio AR, Lanken PN, Kahn JM, Bellamy S, Gallop R, Finkel B, Gracias VH, Fuchs BD, Christie JD. The impact of development of acute lung injury on hospital mortality in critically ill trauma patients. Crit Care Med 2008;36:2309-2315.
19. Christie JD, Ma SF, Aplenc R, Li M, Lanken PN, Shah CV, Fuchs B, Albelda SM, Flores C, Garcia JG. Variation in the MYLK gene is associated with development of acute lung injury after major trauma. Crit Care Med 2008;36:2794-2800.
20. Civil ID, Schwab CW. The Abbreviated Injury Scale, 1985 revision: a condensed chart for clinical use. J Trauma 1988;28:87-90.
21. Sedý J, Zicha J, Kunes J, Jendelová P, Syková E. Mechanisms of neurogenic pulmonary edema development. Physiol Res 2008;57: 499-506.
22. Hudson LD, Milberg JA, Anardi D, Maunder RJ. Clinical risks for development of the acute respiratory distress syndrome. Am J Respir Crit Care Med 1995;151:293-301.
23. Shah CV, Lanken PN, Localio AR, Gallop R, Bellamy S, Ma SF, Flores C, Kahn JM, Finkel B, Fuchs BD, et al. An alternative method of acute lung injury classification for use in observational studies. Chest 2010;138:1054-1061.
24. O'Neal HR Jr, Koyama T, Koehler EA, Siew E, Curtis BR, Fremont RD, May AK, Bernard GR, Ware LB. Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome. Crit Care Med 2011;39:1343-1350.
25. Siew ED, Ware LB, Gebretsadik T, Shintani A, Moons KG, Wickersham N, Bossert F, Ikizler TA. Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J Am Soc Nephrol 2009;20:1823-1832.
26. Fremont RD, Koyama T, Calfee CS, Wu W, Dossett LA, Bossert FR, Mitchell D, Wickersham N, Bernard GR, Matthay MA, et al. Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. J Trauma 2010; 68:1121-1127.
27. Levitt JE, Gould MK, Ware LB, Matthay MA. The pathogenetic and prognostic value of biologic markers in acute lung injury. J Intensive Care Med 2009;24:151-167.
28. Cross LJ, Matthay MA. Biomarkers in acute lung injury: insights into the pathogenesis of acute lung injury. Crit Care Clin 2011;27:355-377.
29. Collins LM, Lanza ST. Latent class and latent transition analysis: with applications in the social, behavioral, and health sciences. Hoboken, NJ: John Wiley & Sons; 2010.
30. Conaway MR. Latent class analysis. In: Armitage P, Colton T, editors. Encyclopedia of biostatistics. Hoboken, NJ: Wiley; 2005.
31. PROC LCA & PROC LTA (version 1.2.7) [Software]. University Park: The Methodology Center, Pennsylvania State University; 2011.
32. Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, Macnee W, et al. Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med 2010;182:598-604.
33. Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, et al.; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2010;181:315-323.
34. Vincent JL, Sakr Y, Groeneveld J, Zandstra DF, Hoste E, Malledant Y, Lei K, Sprung CL. ARDS of early or late onset: does it make a difference? Chest 2010;137:81-87.
35. Justice AC, Covinsky KE, Berlin JA. Assessing the generalizability of prognostic information. Ann Intern Med 1999;130:515-524.
36. van Meurs M, Kümpers P, Ligtenberg JJ, Meertens JH, Molema G, Zijlstra JG. Bench-to-bedside review: angiopoietin signalling in critical illness-a future target? Crit Care 2009;13:207.
37. Fiedler U, Augustin HG. Angiopoietins: a link between angiogenesis and inflammation. Trends Immunol 2006;27:552-558.
38. Agrawal A, Matthay MA, Kangelaris KN, Stein J, Chu JC, Imp BM, Cortez A, Abbott J, Liu KD, Calfee CS. Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. Am J Respir Crit Care Med 2013;187:736-742.
39. Creagh-Brown BC, Quinlan GJ, Evans TW, Burke-Gaffney A. The RAGE axis in systemic inflammation, acute lung injury and myocardial dysfunction: an important therapeutic target? Intensive Care Med 2010;36:1644-1656.
40. Wolfson RK, Chiang ET, Garcia JG. HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption. Microvasc Res 2011;81:189-197.
41. Demling N, Ehrhardt C, Kasper M, Laue M, Knels L, Rieber EP. Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res 2006;323: 475-488.
42. Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, Makita K, Mednick G, Matthay ZA, Matthay MA. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med 2006;173:1008-1015.
43. Cohen MJ, Carles M, Brohi K, Calfee CS, Rahn P, Call MS, Chesebro BB, West MA, Pittet JF. Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans. J Trauma 2010;68:1273-1278.
44. van der Heijden M, van Nieuw Amerongen GP, Chedamni S, van Hinsbergh VW, Johan Groeneveld AB. The angiopoietin-Tie2 system as a therapeutic target in sepsis and acute lung injury. Expert Opin Ther Targets 2009;13:39-53.
45. Sarraf-Yazdi S, Mi J, Moeller BJ, Niu X, White RR, Kontos CD, Sullenger BA, Dewhirst MW, Clary BM. Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer. J Surg Res 2008;146:16-23.
46. White RR, Shan S, Rusconi CP, Shetty G, Dewhirst MW, Kontos CD, Sullenger BA. Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2. Proc Natl Acad Sci USA 2003;100:5028-5033.
47. Lutterloh EC, Opal SM, Pittman DD, Keith JC Jr, Tan XY, Clancy BM, Palmer H, Milarski K, Sun Y, Palardy JE, et al. Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection. Crit Care 2007;11:R122.
48. Lutterloh EC, Opal SM. Antibodies against RAGE in sepsis and inflammation: implications for therapy. Expert Opin Pharmacother 2007;8:1193-1196.