Bone regeneration in a massive rat femur defect through endochondral ossification achieved with chondrogenically differentiated MSCs in a degradable scaffold

Biomaterials

Volumn 35, Issue 27, 2014, Pages 7800-7810

  Harada, Noriko ^a   Watanabe, Yoshinobu ^a   Sato, Kenji ^a   Abe, Satoshi ^a   Yamanaka, Katsuyuki ^b   Sakai, Yuhiro ^b   Kaneko, Tadashi ^b   Matsushita, Takashi ^a  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b GC Corporation   (Japan)

Author keywords

Bone regeneration; Bone tissue engineering; Chondrocytes; Copolymer; Mesenchymal stem cell; Scaffold

Indexed keywords

BIOMECHANICS; BODY FLUIDS; BONE; CARTILAGE; COPOLYMERS; DEFECTS; FLOWCHARTING; RATS; REPAIR; SCAFFOLDS; SCAFFOLDS (BIOLOGY);

BONE REGENERATION; BONE TISSUE ENGINEERING; CHONDROCYTES; ENDOCHONDRAL OSSIFICATION; MESENCHYMAL STEM CELL; MULTIPOTENT CELLS; PLGA SCAFFOLDS; REGENERATIVE MEDICINE;

CELL CULTURE;

COLLAGEN TYPE 2; POLYGLACTIN; TISSUE SCAFFOLD; COLLAGEN; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DEFECT; BONE REGENERATION; BONE STRENGTH; CARTILAGE CELL; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; FRACTURE HEALING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOTOMY; POROSITY; PRIORITY JOURNAL; RAT; TISSUE GROWTH; ANIMAL; BONE DEVELOPMENT; CHEMISTRY; CHONDROGENESIS; CYTOLOGY; EXTERNAL FIXATOR; FEMUR; FISCHER 344 RAT; FLUORESCENT ANTIBODY TECHNIQUE; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RADIOGRAPHY; SCANNING ELECTRON MICROSCOPY; TISSUE SCAFFOLD;

ANIMALS; BIOMECHANICAL PHENOMENA; BONE REGENERATION; CELL DIFFERENTIATION; CHONDROGENESIS; COLLAGEN; EXTERNAL FIXATORS; FEMUR; FLUORESCENT ANTIBODY TECHNIQUE; LACTIC ACID; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICROSCOPY, ELECTRON, SCANNING; OSTEOGENESIS; POLYGLYCOLIC ACID; RATS, INBRED F344; TISSUE SCAFFOLDS; X-RAY MICROTOMOGRAPHY;

EID: 84903462515     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.05.052     Document Type: Article

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