메뉴 건너뛰기




Volumn 16, Issue 9, 2014, Pages

Emerging cytomegalovirus management strategies after solid organ transplantation: Challenges and opportunities

Author keywords

Cytomegalovirus; Outcomes; Prophylaxis; Transplantation; Valganciclovir; Viral load

Indexed keywords

ANTIVIRUS AGENT; ARTESUNATE; BENZIMIDAVIR; BRINCIDOFOVIR; GANCICLOVIR; LEFLUNOMIDE; LETERMOVIR; VALGANCICLOVIR;

EID: 84903401627     PISSN: 15233847     EISSN: 15343146     Source Type: Journal    
DOI: 10.1007/s11908-014-0419-8     Document Type: Review
Times cited : (13)

References (62)
  • 1
    • 53649106006 scopus 로고    scopus 로고
    • Cytomegalovirus seroprevalence and childhood sources of infection: A population-based study among pre-adolescents in the United States
    • Staras SA et al. Cytomegalovirus seroprevalence and childhood sources of infection: A population-based study among pre-adolescents in the United States. J Clin Virol: Off Publ Pan Am Soc Clin Virol. 2008;43(3):266-71.
    • (2008) J Clin Virol: Off Publ Pan Am Soc Clin Virol , vol.43 , Issue.3 , pp. 266-271
    • Staras, S.A.1
  • 4
    • 84880681454 scopus 로고    scopus 로고
    • Cytomegalovirus polyradiculopathy of late onset in a young renal transplant recipient
    • Papasotiriou M et al. Cytomegalovirus polyradiculopathy of late onset in a young renal transplant recipient. Clin Nephrol. 2013;80(1):75-8.
    • (2013) Clin Nephrol , vol.80 , Issue.1 , pp. 75-78
    • Papasotiriou, M.1
  • 5
    • 84880849447 scopus 로고    scopus 로고
    • Cytomegalovirus infection of the major duodenal papilla in a renal allograft recipient with severe biliary obstruction and acalculous cholecystitis
    • Riediger C et al. Cytomegalovirus infection of the major duodenal papilla in a renal allograft recipient with severe biliary obstruction and acalculous cholecystitis. Transplant Infect Dis: Off J Transplant Soc. 2013;15(4):E129-33.
    • (2013) Transplant Infect Dis: Off J Transplant Soc , vol.15 , Issue.4
    • Riediger, C.1
  • 6
    • 84884875750 scopus 로고    scopus 로고
    • Occult cytomegalovirus cholangitis as a potential cause of cholestatic complications after orthotopic liver transplantation? A study of cytomegalovirus DNA in bile
    • Gotthardt DN et al. Occult cytomegalovirus cholangitis as a potential cause of cholestatic complications after orthotopic liver transplantation? A study of cytomegalovirus DNA in bile. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2013;19(10):1142-50.
    • (2013) Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc , vol.19 , Issue.10 , pp. 1142-1150
    • Gotthardt, D.N.1
  • 7
    • 84876850907 scopus 로고    scopus 로고
    • Identification of bacterial infections and clinical manifestation associated with cytomegalovirus in liver transplantation patients
    • Milan A et al. Identification of bacterial infections and clinical manifestation associated with cytomegalovirus in liver transplantation patients. Transplant Proc. 2013;45(3):1130-2.
    • (2013) Transplant Proc , vol.45 , Issue.3 , pp. 1130-1132
    • Milan, A.1
  • 8
    • 84869068043 scopus 로고    scopus 로고
    • Prevalence and clinical impact of cytomegalovirus infection and disease in renal transplantation: Ten years of experience in a single center
    • Giakoustidis D et al. Prevalence and clinical impact of cytomegalovirus infection and disease in renal transplantation: ten years of experience in a single center. Transplant Proc. 2012;44(9):2715-7.
    • (2012) Transplant Proc , vol.44 , Issue.9 , pp. 2715-2717
    • Giakoustidis, D.1
  • 9
    • 84888865862 scopus 로고    scopus 로고
    • Cytomegalovirus & Epstein Barr Virus Serostatus as a predictor of the long term Outcome of Kidney Transplantation
    • Le Page, A.K., et al., Cytomegalovirus & Epstein Barr Virus Serostatus as a predictor of the long term Outcome of Kidney Transplantation. Nephrology, 2013.
    • (2013) Nephrology
    • Le Page, A.K.1
  • 10
    • 84875095263 scopus 로고    scopus 로고
    • Limited impact of cytomegalovirus infection in the long-term outcome of renal and liver transplant
    • San-Juan R et al. Limited impact of cytomegalovirus infection in the long-term outcome of renal and liver transplant. J Clin Virol: Off Publ Pan Am Soc Clin Virol. 2013;56(4):316-22.
    • (2013) J Clin Virol: Off Publ Pan Am Soc Clin Virol , vol.56 , Issue.4 , pp. 316-322
    • San-Juan, R.1
  • 11
    • 84891632036 scopus 로고    scopus 로고
    • CMV Viremia Is Associated With a Decreased Incidence of BKV Reactivation after Kidney and Kidney-Pancreas Transplantation
    • Elfadawy, N., et al., CMV Viremia Is Associated With a Decreased Incidence of BKV Reactivation after Kidney and Kidney-Pancreas Transplantation. Transplantation, 2013.
    • (2013) Transplantation
    • Elfadawy, N.1
  • 12
    • 84881367393 scopus 로고    scopus 로고
    • CMV infection in the donor and increased kidney graft loss: Impact of full HLA-I mismatch and posttransplantation CD8(+) cell reduction
    • Gatault P et al. CMV infection in the donor and increased kidney graft loss: impact of full HLA-I mismatch and posttransplantation CD8(+) cell reduction. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg. 2013;13(8):2119-29.
    • (2013) Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg , vol.13 , Issue.8 , pp. 2119-2129
    • Gatault, P.1
  • 13
    • 84875636414 scopus 로고    scopus 로고
    • High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy
    • Harvala H et al. High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy. J Med Virol. 2013;85(5):893-8.
    • (2013) J Med Virol , vol.85 , Issue.5 , pp. 893-898
    • Harvala, H.1
  • 14
    • 84881547500 scopus 로고    scopus 로고
    • Cytomegalovirus infection post-pancreas-kidney transplantation-results of antiviral prophylaxis in high-risk patients
    • Fallatah SMet al. Cytomegalovirus infection post-pancreas-kidney transplantation-results of antiviral prophylaxis in high-risk patients. Clin Transpl. 2013;27(4):503-9.
    • (2013) Clin Transpl , vol.27 , Issue.4 , pp. 503-509
    • Fallatah, S.M.1
  • 15
    • 84866934556 scopus 로고    scopus 로고
    • Cytomegalovirus disease in renal transplant recipients: A single-center experience
    • Bhadauria D et al. Cytomegalovirus disease in renal transplant recipients: a single-center experience. Indian J Microbiol. 2012;52(3):510-5.
    • (2012) Indian J Microbiol , vol.52 , Issue.3 , pp. 510-515
    • Bhadauria, D.1
  • 16
    • 84873320001 scopus 로고    scopus 로고
    • Six-month low-dose valganciclovir prophylaxis in cytomegalovirus D+/R- kidney transplant patients receiving thymoglobulin induction
    • Luan FL. Six-month low-dose valganciclovir prophylaxis in cytomegalovirus D+/R- kidney transplant patients receiving thymoglobulin induction. Transplant Proc. 2013;45(1):175-7.
    • (2013) Transplant Proc , vol.45 , Issue.1 , pp. 175-177
    • Luan, F.L.1
  • 17
    • 84879696144 scopus 로고    scopus 로고
    • Decreased incidence of cytomegalovirus infection with sirolimus in a post hoc randomized, multicenter study in lung transplantation
    • Ghassemieh B et al. Decreased incidence of cytomegalovirus infection with sirolimus in a post hoc randomized, multicenter study in lung transplantation. J Heart Lung Transplant: Off Publ Int Soc Heart Transplant. 2013;32(7):701-6.
    • (2013) J Heart Lung Transplant: Off Publ Int Soc Heart Transplant , vol.32 , Issue.7 , pp. 701-706
    • Ghassemieh, B.1
  • 18
    • 84875942737 scopus 로고    scopus 로고
    • Everolimus is associated with a reduced incidence of cytomegalovirus infection following de novo cardiac transplantation
    • Kobashigawa J et al. Everolimus is associated with a reduced incidence of cytomegalovirus infection following de novo cardiac transplantation. Transplant Infect Dis: Off J Transplant Soc. 2013;15(2):150-62.
    • (2013) Transplant Infect Dis: Off J Transplant Soc , vol.15 , Issue.2 , pp. 150-162
    • Kobashigawa, J.1
  • 19
    • 84872083283 scopus 로고    scopus 로고
    • Everolimus-treated renal transplant recipients have a more robust CMV-specific CD8+ T-cell response compared with cyclosporine- or mycophenolate-treated patients
    • Havenith SH et al. Everolimus-treated renal transplant recipients have a more robust CMV-specific CD8+ T-cell response compared with cyclosporine- or mycophenolate-treated patients. Transplantation. 2013;95(1):184-91.
    • (2013) Transplantation , vol.95 , Issue.1 , pp. 184-191
    • Havenith, S.H.1
  • 21
    • 84884969313 scopus 로고    scopus 로고
    • Clinical utility of viral load in management of cytomegalovirus infection after solid organ transplantation
    • Razonable RR, Hayden RT. Clinical utility of viral load in management of cytomegalovirus infection after solid organ transplantation. Clin Microbiol Rev. 2013;26(4):703-27.
    • (2013) Clin Microbiol Rev , vol.26 , Issue.4 , pp. 703-727
    • Razonable, R.R.1    Hayden, R.T.2
  • 22
    • 84872281120 scopus 로고    scopus 로고
    • An international multicenter performance analysis of cytomegalovirus load tests
    • This study, which compared the performance characteristics of CMV nucleic acid tests, reports an improved concordance among the various assays that have been optimized using the first WHO international calibration standard
    • • Hirsch HH et al. An international multicenter performance analysis of cytomegalovirus load tests. Clin Infect Dis: Off Publ Infect Dis Soc Am. 2013;56(3):367-73. This study, which compared the performance characteristics of CMV nucleic acid tests, reports an improved concordance among the various assays that have been optimized using the first WHO international calibration standard.
    • (2013) Clin Infect Dis: Off Publ Infect Dis Soc Am , vol.56 , Issue.3 , pp. 367-373
    • Hirsch, H.H.1
  • 23
    • 84877274937 scopus 로고    scopus 로고
    • Virologic suppression measured by a cytomegalovirus (CMV) DNA test calibrated to the World Health Organization international standard is predictive of CMV disease resolution in transplant recipients
    • This study desribes the potential clinical application of a CMV nucleic acid test that has been standardized using the WHO calibrator. higher the viral load was associated with longer time to clinical disease resolution, while suppression of viral load to less than 137 IU/ml was associated with faster resolution of CMV disease
    • • Razonable RR et al. Virologic suppression measured by a cytomegalovirus (CMV) DNA test calibrated to the World Health Organization international standard is predictive of CMV disease resolution in transplant recipients. Clin Infect Dis: Off Publ Infect Dis Soc Am. 2013;56(11):1546-53. This study desribes the potential clinical application of a CMV nucleic acid test that has been standardized using the WHO calibrator. higher the viral load was associated with longer time to clinical disease resolution, while suppression of viral load to less than 137 IU/ml was associated with faster resolution of CMV disease.
    • (2013) Clin Infect Dis: Off Publ Infect Dis Soc Am , vol.56 , Issue.11 , pp. 1546-1553
    • Razonable, R.R.1
  • 24
    • 84887859988 scopus 로고    scopus 로고
    • Detection of cytomegalovirus DNA in plasma as an adjunct diagnostic for gastrointestinal tract disease in kidney and liver transplant recipients
    • This study desribes the potential clinical utility of the CMV nucleic acid test in the blood as a noninvasive method for the diagnosis of gastrointestinal CMV disease in transplant recipients
    • • Durand CM et al. Detection of cytomegalovirus DNA in plasma as an adjunct diagnostic for gastrointestinal tract disease in kidney and liver transplant recipients. Clin Infect Dis: Off Publ Infect Dis Soc Am. 2013;57(11):1550-9. This study desribes the potential clinical utility of the CMV nucleic acid test in the blood as a noninvasive method for the diagnosis of gastrointestinal CMV disease in transplant recipients.
    • (2013) Clin Infect Dis: Off Publ Infect Dis Soc Am , vol.57 , Issue.11 , pp. 1550-1559
    • Durand, C.M.1
  • 25
    • 84874828991 scopus 로고    scopus 로고
    • Cytomegalovirus in solid organ transplantation
    • This article serves as the guideline for the diagnsosis, prevention, and treatment of CMV infection and disease in solid organ transplantation, as endorsed by the American Society of Transplantation
    • • Razonable RR, Humar A. Cytomegalovirus in solid organ transplantation. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg. 2013;13 Suppl 4:93-106. This article serves as the guideline for the diagnsosis, prevention, and treatment of CMV infection and disease in solid organ transplantation, as endorsed by the American Society of Transplantation.
    • (2013) Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg , vol.13 , Issue.SUPPL. 4 , pp. 93-106
    • Razonable, R.R.1    Humar, A.2
  • 27
    • 78650819624 scopus 로고    scopus 로고
    • Extended valganciclovir prophylaxis in D+/Rkidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: Two-year results of the IMPACT study
    • Humar A et al. Extended valganciclovir prophylaxis in D+/Rkidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: two-year results of the IMPACT study. Transplantation. 2010;90(12):1427-31.
    • (2010) Transplantation , vol.90 , Issue.12 , pp. 1427-1431
    • Humar, A.1
  • 28
    • 84879550846 scopus 로고    scopus 로고
    • Pretransplant immediately early-1-specific T cell responses provide protection for CMV infection after kidney transplantation
    • Bestard O et al. Pretransplant immediately early-1-specific T cell responses provide protection for CMV infection after kidney transplantation. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg. 2013;13(7):1793-805.
    • (2013) Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg , vol.13 , Issue.7 , pp. 1793-1805
    • Bestard, O.1
  • 29
    • 84874446978 scopus 로고    scopus 로고
    • Pretransplant interferon-gamma secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation
    • Cantisan S et al. Pretransplant interferon-gamma secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg. 2013;13(3):738-45.
    • (2013) Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg , vol.13 , Issue.3 , pp. 738-745
    • Cantisan, S.1
  • 30
    • 84855848791 scopus 로고    scopus 로고
    • Clinical utility of cytomegalovirus cell-mediated immunity in transplant recipients with cytomegalovirus viremia
    • Lisboa LF et al. Clinical utility of cytomegalovirus cell-mediated immunity in transplant recipients with cytomegalovirus viremia. Transplantation. 2012;93(2):195-200.
    • (2012) Transplantation , vol.93 , Issue.2 , pp. 195-200
    • Lisboa, L.F.1
  • 31
    • 84874774789 scopus 로고    scopus 로고
    • Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: A multicenter cohort study
    • This study describes the potential utility of an interferongamma release assay for assessing the risk of late-onset CMV disease in high-risk CMV D+/R- solid organ transplant recipients
    • • Manuel O et al. Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a multicenter cohort study. Clin Infect Dis: Off Publ Infect Dis Soc Am. 2013;56(6): 817-24. This study describes the potential utility of an interferongamma release assay for assessing the risk of late-onset CMV disease in high-risk CMV D+/R- solid organ transplant recipients.
    • (2013) Clin Infect Dis: Off Publ Infect Dis Soc Am , vol.56 , Issue.6 , pp. 817-824
    • Manuel, O.1
  • 32
    • 84875538702 scopus 로고    scopus 로고
    • Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients
    • Hodson EM et al. Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients. Cochrane Database Syst Rev. 2013;2, CD003774.
    • (2013) Cochrane Database Syst Rev , vol.2
    • Hodson, E.M.1
  • 34
    • 84870927678 scopus 로고    scopus 로고
    • Risk of cytomegalovirus disease in high-risk liver transplant recipients on valganciclovir prophylaxis: A systematic review and meta-analysis
    • Kalil AC et al. Risk of cytomegalovirus disease in high-risk liver transplant recipients on valganciclovir prophylaxis: a systematic review and meta-analysis. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc. 2012;18(12):1440-7.
    • (2012) Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc , vol.18 , Issue.12 , pp. 1440-1447
    • Kalil, A.C.1
  • 35
    • 84887056297 scopus 로고    scopus 로고
    • Low-dose valganciclovir for cytomegalovirus prophylaxis in heart transplant recipients
    • Julian KG et al. Low-dose valganciclovir for cytomegalovirus prophylaxis in heart transplant recipients. Transplant Proc. 2013;45(9):3414-7.
    • (2013) Transplant Proc , vol.45 , Issue.9 , pp. 3414-3417
    • Julian, K.G.1
  • 36
    • 84874831061 scopus 로고    scopus 로고
    • Clinical outcome with low-dose valacyclovir in highrisk renal transplant recipients: A 10-year experience
    • Sund F et al. Clinical outcome with low-dose valacyclovir in highrisk renal transplant recipients: a 10-year experience. Nephrol Dial Transplant: Off Publ Eur Dial Transplant Assoc Eur Ren Assoc. 2013;28(3):758-65.
    • (2013) Nephrol Dial Transplant: Off Publ Eur Dial Transplant Assoc Eur Ren Assoc , vol.28 , Issue.3 , pp. 758-765
    • Sund, F.1
  • 37
    • 77954070106 scopus 로고    scopus 로고
    • Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: A randomized, controlled trial
    • Palmer SM et al. Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: a randomized, controlled trial. Ann Intern Med. 2010;152(12):761-9.
    • (2010) Ann Intern Med , vol.152 , Issue.12 , pp. 761-769
    • Palmer, S.M.1
  • 38
    • 84875947788 scopus 로고    scopus 로고
    • Cytomegalovirus disease in lung transplantation: Impact of recipient seropositivity and duration of antiviral prophylaxis
    • Hammond SP et al. Cytomegalovirus disease in lung transplantation: impact of recipient seropositivity and duration of antiviral prophylaxis. Transplant Infect Dis: Off J Transplant Soc. 2013;15(2):163-70.
    • (2013) Transplant Infect Dis: Off J Transplant Soc , vol.15 , Issue.2 , pp. 163-170
    • Hammond, S.P.1
  • 39
    • 84863398725 scopus 로고    scopus 로고
    • Cytomegalovirus disease and infection in lung transplant recipients in the setting of planned indefinite valganciclovir prophylaxis
    • Wiita AP et al. Cytomegalovirus disease and infection in lung transplant recipients in the setting of planned indefinite valganciclovir prophylaxis. Transplant Infect Dis: Off J Transplant Soc. 2012;14(3):248-58.
    • (2012) Transplant Infect Dis: Off J Transplant Soc , vol.14 , Issue.3 , pp. 248-258
    • Wiita, A.P.1
  • 40
    • 84856970327 scopus 로고    scopus 로고
    • Incidence of cytomegalovirus UL97 and UL54 amino acid substitutions detected after 100 or 200 days of valganciclovir prophylaxis
    • Boivin G et al. Incidence of cytomegalovirus UL97 and UL54 amino acid substitutions detected after 100 or 200 days of valganciclovir prophylaxis. J Clin Virol: Off Publ Pan Am Soc Clin Virol. 2012;53(3):208-13.
    • (2012) J Clin Virol: Off Publ Pan Am Soc Clin Virol , vol.53 , Issue.3 , pp. 208-213
    • Boivin, G.1
  • 41
    • 84875510406 scopus 로고    scopus 로고
    • Pre-emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients
    • Owers DS et al. Pre-emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients. Cochrane Database Syst Rev. 2013;2, CD005133.
    • (2013) Cochrane Database Syst Rev , vol.2
    • Owers, D.S.1
  • 42
    • 84874105701 scopus 로고    scopus 로고
    • A stringent preemptive protocol reduces cytomegalovirus disease in the first 6 months after kidney transplantation
    • Greiner M et al. A stringent preemptive protocol reduces cytomegalovirus disease in the first 6 months after kidney transplantation. Infection. 2012;40(6):669-75.
    • (2012) Infection , vol.40 , Issue.6 , pp. 669-675
    • Greiner, M.1
  • 43
    • 84869029977 scopus 로고    scopus 로고
    • Cumulative incidence of cytomegalovirus infection and disease after heart transplantation in the last decade: Effect of preemptive therapy
    • Mendez-Eirin E et al. Cumulative incidence of cytomegalovirus infection and disease after heart transplantation in the last decade: effect of preemptive therapy. Transplant Proc. 2012;44(9):2660-2.
    • (2012) Transplant Proc , vol.44 , Issue.9 , pp. 2660-2662
    • Mendez-Eirin, E.1
  • 44
    • 84866335435 scopus 로고    scopus 로고
    • Preemptive therapy in the prevention of cytomegalovirus disease in high- and low-risk heart transplant recipients
    • Casquero S et al. Preemptive therapy in the prevention of cytomegalovirus disease in high- and low-risk heart transplant recipients. Transplant Proc. 2012;44(7):2113-4.
    • (2012) Transplant Proc , vol.44 , Issue.7 , pp. 2113-2114
    • Casquero, S.1
  • 45
    • 84875809117 scopus 로고    scopus 로고
    • Prospective study on CMV-reactivations under preemptive strategy in CMV-seropositive adult liver transplant recipients
    • Lautenschlager I et al. Prospective study on CMV-reactivations under preemptive strategy in CMV-seropositive adult liver transplant recipients. J Clin Virol: Off Publ Pan Am Soc Clin Virol. 2013;57(1):50-3.
    • (2013) J Clin Virol: Off Publ Pan Am Soc Clin Virol , vol.57 , Issue.1 , pp. 50-53
    • Lautenschlager, I.1
  • 46
    • 84871516782 scopus 로고    scopus 로고
    • Determination, validation and standardization of a CMV DNA cut-off value in plasma for preemptive treatment of CMV infection in solid organ transplant recipients at lower risk for CMV infection
    • Martin-Gandul C et al. Determination, validation and standardization of a CMV DNA cut-off value in plasma for preemptive treatment of CMV infection in solid organ transplant recipients at lower risk for CMV infection. J Clin Virol: Off Publ Pan Am Soc Clin Virol. 2013;56(1):13-8.
    • (2013) J Clin Virol: Off Publ Pan Am Soc Clin Virol , vol.56 , Issue.1 , pp. 13-18
    • Martin-Gandul, C.1
  • 47
    • 84878010896 scopus 로고    scopus 로고
    • Evaluation of clinical outcomes of prophylactic versus preemptive cytomegalovirus strategy in liver transplant recipients
    • Onor IO et al. Evaluation of clinical outcomes of prophylactic versus preemptive cytomegalovirus strategy in liver transplant recipients. Transplant Int: Off J Eur Soc Organ Transplant. 2013;26(6):592-600.
    • (2013) Transplant Int: Off J Eur Soc Organ Transplant , vol.26 , Issue.6 , pp. 592-600
    • Onor, I.O.1
  • 48
    • 84883453128 scopus 로고    scopus 로고
    • Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients
    • Manuel O et al. Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg. 2013;13(9):2402-10.
    • (2013) Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg , vol.13 , Issue.9 , pp. 2402-2410
    • Manuel, O.1
  • 49
    • 84905713622 scopus 로고    scopus 로고
    • Ganciclovir-resistant cytomegalovirus (CMV) infections among lung transplant recipients are associated with poor outcomes despite treatment with foscarnet-containing regimens
    • Minces, L.R., et al., Ganciclovir-resistant cytomegalovirus (CMV) infections among lung transplant recipients are associated with poor outcomes despite treatment with foscarnet-containing regimens. Antimicrobial agents and chemotherapy, 2013.
    • (2013) Antimicrobial Agents and Chemotherapy
    • Minces, L.R.1
  • 50
    • 78049355534 scopus 로고    scopus 로고
    • Antiviral drug resistance of human cytomegalovirus
    • Lurain NS, Chou S. Antiviral drug resistance of human cytomegalovirus. Clin Microbiol Rev. 2010;23(4):689-712.
    • (2010) Clin Microbiol Rev , vol.23 , Issue.4 , pp. 689-712
    • Lurain, N.S.1    Chou, S.2
  • 51
    • 84905713619 scopus 로고    scopus 로고
    • Panresistant Cytomegalovirus in a Kidney Transplant Recipient
    • Yost, S.E., et al., Panresistant Cytomegalovirus in a Kidney Transplant Recipient. Pharmacotherapy, 2013.
    • (2013) Pharmacotherapy
    • Yost, S.E.1
  • 52
    • 84905713620 scopus 로고    scopus 로고
    • Success and failure of artesunate treatment in five transplant recipients with disease caused by drug-resistant cytomegalovirus
    • Germi, R., et al., Success and failure of artesunate treatment in five transplant recipients with disease caused by drug-resistant cytomegalovirus. Antiviral research, 2013.
    • (2013) Antiviral Research
    • Germi, R.1
  • 53
    • 84884528238 scopus 로고    scopus 로고
    • CMX001 to Prevent Cytomegalovirus Disease in Hematopoietic-Cell Transplantation
    • This study provides early indication about the safety and efficacy of liposomal cidofovir for the prevention of infection in transplantation
    • • Marty FM et al. CMX001 to Prevent Cytomegalovirus Disease in Hematopoietic-Cell Transplantation. N Engl J Med. 2013;369(13): 1227-36. This study provides early indication about the safety and efficacy of liposomal cidofovir for the prevention of infection in transplantation.
    • (2013) N Engl J Med , vol.369 , Issue.13 , pp. 1227-1236
    • Marty, F.M.1
  • 54
    • 84868200175 scopus 로고    scopus 로고
    • Efficacy and Safety of Maribavir Dosed at 100mg Orally Twice Daily for the Prevention of Cytomegalovirus Disease in Liver Transplant Recipients: A Randomized, Double-Blind, Multicenter Controlled Trial
    • Winston DJ et al. Efficacy and Safety of Maribavir Dosed at 100mg Orally Twice Daily for the Prevention of Cytomegalovirus Disease in Liver Transplant Recipients: A Randomized, Double-Blind, Multicenter Controlled Trial. Am J Transplant. 2012;12(11):3021-30.
    • (2012) Am J Transplant , vol.12 , Issue.11 , pp. 3021-3030
    • Winston, D.J.1
  • 55
    • 84868200175 scopus 로고    scopus 로고
    • Efficacy and safety of maribavir dosed at 100 mg orally twice daily for the prevention of cytomegalovirus disease in liver transplant recipients: A randomized, double-blind, multicenter controlled trial
    • Winston DJ et al. Efficacy and safety of maribavir dosed at 100 mg orally twice daily for the prevention of cytomegalovirus disease in liver transplant recipients: a randomized, double-blind, multicenter controlled trial. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg. 2012;12(11):3021-30.
    • (2012) Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg , vol.12 , Issue.11 , pp. 3021-3030
    • Winston, D.J.1
  • 56
    • 84878608183 scopus 로고    scopus 로고
    • Maribavir use in practice for cytomegalovirus infection in French transplantation centers
    • Alain S et al. Maribavir use in practice for cytomegalovirus infection in French transplantation centers. Transplant Proc. 2013;45(4):1603-7.
    • (2013) Transplant Proc , vol.45 , Issue.4 , pp. 1603-1607
    • Alain, S.1
  • 57
    • 84905713612 scopus 로고    scopus 로고
    • Pre-emptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: Results of a Phase 2a study
    • This study describes the early evidence for the efficacy and safety of a novel drug, letermovir, for the management of CMV infection after transplantation
    • • Stoelben, S., et al., Pre-emptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study. Transplant international : official journal of the European Society for Organ Transplantation, 2013. This study describes the early evidence for the efficacy and safety of a novel drug, letermovir, for the management of CMV infection after transplantation.
    • (2013) Transplant International: Official Journal of the European Society for Organ Transplantation
    • Stoelben, S.1
  • 58
    • 84863860973 scopus 로고    scopus 로고
    • Sensitive and rapid detection of ganciclovir resistance by PCR based MALDI-TOF analysis
    • Zurcher S et al. Sensitive and rapid detection of ganciclovir resistance by PCR based MALDI-TOF analysis. J Clin Virol: Off Publ Pan Am Soc Clin Virol. 2012;54(4):359-63.
    • (2012) J Clin Virol: Off Publ Pan Am Soc Clin Virol , vol.54 , Issue.4 , pp. 359-363
    • Zurcher, S.1
  • 59
    • 84859007690 scopus 로고    scopus 로고
    • A novel therapeutic cytomegalovirus DNAvaccine in allogeneic haemopoietic stem-cell transplantation: A randomised, double-blind, placebo-controlled, phase 2 trial
    • Kharfan-Dabaja MA et al. A novel therapeutic cytomegalovirus DNAvaccine in allogeneic haemopoietic stem-cell transplantation: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Infect Dis. 2012;12(4):290-9.
    • (2012) Lancet Infect Dis , vol.12 , Issue.4 , pp. 290-299
    • Kharfan-Dabaja, M.A.1
  • 60
    • 62749097289 scopus 로고    scopus 로고
    • Vaccine prevention of maternal cytomegalovirus infection
    • Pass RF et al. Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med. 2009;360(12):1191-9.
    • (2009) N Engl J Med , vol.360 , Issue.12 , pp. 1191-1199
    • Pass, R.F.1
  • 61
    • 84890789457 scopus 로고    scopus 로고
    • The role of therapeutic drug monitoring in the treatment of cytomegalovirus disease in kidney transplantation
    • Bedino, G., et al., The role of therapeutic drug monitoring in the treatment of cytomegalovirus disease in kidney transplantation. International urology and nephrology, 2012.
    • (2012) International Urology and Nephrology
    • Bedino, G.1
  • 62
    • 84888882484 scopus 로고    scopus 로고
    • Critical analysis of valganciclovir dosing and renal function on the development of cytomegalovirus infection in kidney transplantation
    • Posadas Salas, M.A., et al., Critical analysis of valganciclovir dosing and renal function on the development of cytomegalovirus infection in kidney transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2013.
    • (2013) Transplant Infectious Disease: An Official Journal of the Transplantation Society
    • Posadas Salas, M.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.