Development and validation of a capillary electrophoresis method for determination of enantiomeric purity and related substances of esomeprazole in raw material and pellets

Electrophoresis

Volumn 35, Issue 6, 2014, Pages 804-810

  Estevez, Pablo ^a   Flor, Sabrina ^a   Boscolo, Oriana ^a   Tripodi, Valeria ^a,b   Lucangioli, Silvia ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Chiral capillary electrophoresis; Enantiomeric purity; Esomeprazole; Omeprazole; Related substances

Indexed keywords

CAPILLARY ELECTROPHORESIS; DRUG PRODUCTS; ELECTROLYTES; ENANTIOMERS; IMPURITIES; PELLETIZING;

BUFFER PH; CHIRAL CAPILLARY ELECTROPHORESIS; ENANTIOMERIC PURITY; ESOMEPRAZOLE; OMEPRAZOLE; OPTIMIZED SYSTEM; PHOSPHATE BUFFERS; RELATED SUBSTANCES; S-ENANTIOMERS; Β-CD;

QUALITY CONTROL;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ANTIOXIDANT; ESOMEPRAZOLE; OMEPRAZOLE; SODIUM DITHIONITE;

ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG IMPURITY; DRUG PELLET; DRUG PURITY; DRUG STRUCTURE; ENANTIOMER; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; QUALITY CONTROL; VALIDATION STUDY;

CHIRAL CAPILLARY ELECTROPHORESIS; ENANTIOMERIC PURITY; ESOMEPRAZOLE; OMEPRAZOLE; RELATED SUBSTANCES;

DELAYED-ACTION PREPARATIONS; ELECTROPHORESIS, CAPILLARY; ESOMEPRAZOLE; HYDROGEN-ION CONCENTRATION; LIMIT OF DETECTION; LINEAR MODELS; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM;

EID: 84903372596     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201300334     Document Type: Article

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