메뉴 건너뛰기




Volumn 35, Issue 6, 2014, Pages 1513.e1-1513.e5

Polymorphisms in BACE2 may affect the age of onset Alzheimer's dementia in Down syndrome

Author keywords

Alzheimer's disease; BACE2; Down syndrome; Rs2252576

Indexed keywords

3' UNTRANSLATED REGION; ADULT; ALZHEIMER DISEASE; ARTICLE; BACE2 GENE; CHROMOSOME 21; CONTROLLED STUDY; DOWN SYNDROME; EXON; FEMALE; GENE; GENE DUPLICATION; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; ALLELE; COHORT ANALYSIS; COMPLICATION; GENETIC ASSOCIATION; GENETICS; MIDDLE AGED;

EID: 84903370910     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.12.022     Document Type: Article
Times cited : (34)

References (18)
  • 2
    • 49749099317 scopus 로고    scopus 로고
    • Protein expression of BACE1, BACE2 and APP in Down syndrome brains
    • Cheon M.S., Dierssen M., Kim S.H., Lubec G. Protein expression of BACE1, BACE2 and APP in Down syndrome brains. Amino Acids 2008, 35:339-343. 10.1007/s00726-007-0618-9.
    • (2008) Amino Acids , vol.35 , pp. 339-343
    • Cheon, M.S.1    Dierssen, M.2    Kim, S.H.3    Lubec, G.4
  • 6
    • 84879880379 scopus 로고    scopus 로고
    • Evidence that PICALM affects age at onset of Alzheimer's dementia in Down syndrome
    • 2441.e1-2441.e5
    • Jones E.L., Mok K., Hanney M., Harold D., Sims R., Williams J., Ballard C. Evidence that PICALM affects age at onset of Alzheimer's dementia in Down syndrome. Neurobiol. Aging 2013, 34:2441.e1-2441.e5. 10.1016/j.neurobiolaging.2013.03.018.
    • (2013) Neurobiol. Aging , vol.34
    • Jones, E.L.1    Mok, K.2    Hanney, M.3    Harold, D.4    Sims, R.5    Williams, J.6    Ballard, C.7
  • 9
    • 0025038831 scopus 로고
    • Some morphometric observations on the brains of patients with Down's syndrome: their relationship to age and dementia
    • Mann D.M., Royston M.C., Ravindra C.R. Some morphometric observations on the brains of patients with Down's syndrome: their relationship to age and dementia. J.Neurol. Sci. 1990, 99:153-164.
    • (1990) J.Neurol. Sci. , vol.99 , pp. 153-164
    • Mann, D.M.1    Royston, M.C.2    Ravindra, C.R.3
  • 10
    • 34248574203 scopus 로고    scopus 로고
    • Fifteen-year follow-up of 92 hospitalized adults with Down's syndrome: incidence of cognitive decline, its relationship to age and neuropathology
    • Margallo-Lana M.L., Moore P.B., Kay D.W., Perry R.H., Reid B.E., Berney T.P., Tyrer S.P. Fifteen-year follow-up of 92 hospitalized adults with Down's syndrome: incidence of cognitive decline, its relationship to age and neuropathology. J.Intellect. Disabil. Res. 2007, 51(Pt. 6):463-477. 10.1111/j.1365-2788.2006.00902.x.
    • (2007) J.Intellect. Disabil. Res. , vol.51 , Issue.PART. 6 , pp. 463-477
    • Margallo-Lana, M.L.1    Moore, P.B.2    Kay, D.W.3    Perry, R.H.4    Reid, B.E.5    Berney, T.P.6    Tyrer, S.P.7
  • 14
    • 0027364069 scopus 로고
    • Age of onset and duration of dementia in people with Down syndrome: integration of 98 reported cases in the literature
    • Prasher V.P., Krishnan V.H. Age of onset and duration of dementia in people with Down syndrome: integration of 98 reported cases in the literature. Int. J. Geriatr. Psychiatry 1993, 8:915-922.
    • (1993) Int. J. Geriatr. Psychiatry , vol.8 , pp. 915-922
    • Prasher, V.P.1    Krishnan, V.H.2
  • 16
    • 84863304598 scopus 로고    scopus 로고
    • R: A Language and Environment for Statistical Computing
    • R Core Team, R Foundation for Statistical Computing, Vienna, Austria.
    • R Core Team. 2013. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. http://www.R-project.org.
    • (2013)
  • 17
    • 33746549926 scopus 로고    scopus 로고
    • BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome
    • Sun X., He G., Song W. BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome. Faseb J. 2006, 20:1369-1376. 10.1096/fj.05-5632com.
    • (2006) Faseb J. , vol.20 , pp. 1369-1376
    • Sun, X.1    He, G.2    Song, W.3
  • 18
    • 63349085109 scopus 로고    scopus 로고
    • Lack of association between the polymorphisms of beta-site APP-cleaving enzyme 2 (BACE2) 5'-flanking region and sporadic Alzheimer's disease
    • Yu Y., Jia J. Lack of association between the polymorphisms of beta-site APP-cleaving enzyme 2 (BACE2) 5'-flanking region and sporadic Alzheimer's disease. Brain Res. 2009, 1257:10-15. 10.1016/j.brainres.2008.12.024.
    • (2009) Brain Res. , vol.1257 , pp. 10-15
    • Yu, Y.1    Jia, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.