Peroxisome proliferator-activated receptor γ agonist rosiglitazone inhibits migration and invasion of prostate cancer cells through inhibition of the CXCR4/CXCL12 axis

Molecular Medicine Reports

Volumn 10, Issue 2, 2014, Pages 695-700

  Qin, Liang ^a   Gong, Chen ^a   Chen, An Min ^a   Guo, Feng Jing ^a   Xu, Fei ^a   Ren, Ye ^a   Liao, Hui ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

CXCR4; Invasion; Peroxisome proliferator activated receptor ; Prostate cancer

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; CHEMOKINE RECEPTOR CXCR4; GELATINASE A; GELATINASE B; MESSENGER RNA; PROTEIN KINASE B; ROSIGLITAZONE; VASCULOTROPIN; 2,4 THIAZOLIDINEDIONE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; CANCER CELL; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MALE; PROSTATE CARCINOMA; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL MOTION; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CXCL12; HUMANS; MALE; PHOSPHATIDYLINOSITOL 3-KINASES; PPAR GAMMA; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CXCR4; RNA, MESSENGER; THIAZOLIDINEDIONES;

EID: 84903303562     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2232     Document Type: Article

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