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Volumn 58, Issue 7, 2014, Pages 3904-3913

Metabolic compensation of fitness costs associated with overexpression of the multidrug efflux pump MexEF-OprN in Pseudomonas aeruginosa

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CHLORAMPHENICOL; MESSENGER RNA; MULTIDRUG EFFLUX PUMP MEXEF OPRN PROTEIN; NITRIC OXIDE; PROTON; UNCLASSIFIED DRUG; NITRIC ACID DERIVATIVE; OPRN PROTEIN, PSEUDOMONAS AERUGINOSA; OUTER MEMBRANE PROTEIN;

EID: 84903147757     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00121-14     Document Type: Article
Times cited : (43)

References (74)
  • 1
    • 23944475626 scopus 로고    scopus 로고
    • Mechanisms of, and barriers to, horizontal gene transfer between bacteria
    • DOI 10.1038/nrmicro1234
    • Thomas CM, Nielsen KM. 2005. Mechanisms of, and barriers to, horizontal gene transfer between bacteria. Nat. Rev. Microbiol. 3:711-721. http://dx.doi.org/10.1038/nrmicro1234. (Pubitemid 41195087)
    • (2005) Nature Reviews Microbiology , vol.3 , Issue.9 , pp. 711-721
    • Thomas, C.M.1    Nielsen, K.M.2
  • 2
    • 0033936567 scopus 로고    scopus 로고
    • Mutation frequencies and antibiotic resistance
    • DOI 10.1128/AAC.44.7.1771-1777.2000
    • Martinez JL, Baquero F. 2000. Mutation frequencies and antibiotic resistance. Antimicrob. Agents Chemother. 44:1771-1777. http://dx.doi.org/10. 1128/AAC.44.7.1771-1777.2000. (Pubitemid 30422923)
    • (2000) Antimicrobial Agents and Chemotherapy , vol.44 , Issue.7 , pp. 1771-1777
    • Martinez, J.L.1    Baquero, F.2
  • 3
    • 0032870940 scopus 로고    scopus 로고
    • The biological cost of antibiotic resistance
    • DOI 10.1016/S1369-5274(99)00005-3
    • Andersson DI, Levin BR. 1999. The biological cost of antibiotic resistance. Curr. Opin.Microbiol. 2:489-493. http://dx.doi.org/10.1016/S1369- 5274(99)00005-3. (Pubitemid 29477174)
    • (1999) Current Opinion in Microbiology , vol.2 , Issue.5 , pp. 489-493
    • Andersson, D.I.1    Levin, B.R.2
  • 4
    • 33747601416 scopus 로고    scopus 로고
    • Is antibiotic cycling the answer to preventing the emergence of bacterial resistance in the intensive care unit?
    • DOI 10.1086/504484
    • Kollef MH. 2006. Is antibiotic cycling the answer to preventing the emergence of bacterial resistance in the intensive care unit? Clin. Infect. Dis. 43(Suppl 2):S82-S88. http://dx.doi.org/10.1086/504484. (Pubitemid 44267145)
    • (2006) Clinical Infectious Diseases , vol.43 , Issue.SUPPL. 2
    • Kollef, M.H.1
  • 5
    • 47749155981 scopus 로고    scopus 로고
    • Antibiotics and antibiotic resistance genes in natural environments
    • DOI 10.1126/science.1159483
    • Martinez JL. 2008. Antibiotics and antibiotic resistance genes in natural environments. Science 321:365-367. http://dx.doi.org/10.1126/science.1159483. (Pubitemid 352029941)
    • (2008) Science , vol.321 , Issue.5887 , pp. 365-367
    • Martinez, J.L.1
  • 7
    • 69249205465 scopus 로고    scopus 로고
    • Environmental pollution by antibiotics and by antibiotic resistance determinants
    • Martinez JL. 2009. Environmental pollution by antibiotics and by antibiotic resistance determinants. Environ. Pollut. 157:2893-2902. http://dx.doi.org/10.1016/j.envpol.2009.05.051.
    • (2009) Environ. Pollut. , vol.157 , pp. 2893-2902
    • Martinez, J.L.1
  • 8
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: Is it possible to reverse resistance?
    • Andersson DI, Hughes D. 2010. Antibiotic resistance and its cost: is it possible to reverse resistance? Nat. Rev. Microbiol. 8:260-271. http://dx.doi.org/10.1038/nrmicro2319.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2
  • 9
    • 13944274432 scopus 로고    scopus 로고
    • Drug resistance and fitness in Mycobacterium tuberculosis infection
    • Reply, 191:824, http://dx.doi.org/10.1086/427520
    • Bottger EC, Pletschette M, Andersson D. 2005. Drug resistance and fitness in Mycobacterium tuberculosis infection. J. Infect. Dis. 191:823-824. http://dx.doi.org/10.1086/427517. (Reply, 191:824, http://dx.doi.org/10.1086/ 427520.)
    • (2005) J. Infect. Dis. , vol.191 , pp. 823-824
    • Bottger, E.C.1    Pletschette, M.2    Andersson, D.3
  • 10
    • 80053124273 scopus 로고    scopus 로고
    • Beyond serial passages: New methods for predicting the emergence of resistance to novel antibiotics
    • Martinez JL, Baquero F, Andersson DI. 2011. Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics. Curr. Opin. Pharmacol. 11:439-445. http://dx.doi.org/10.1016/j.coph.2011.07.005.
    • (2011) Curr. Opin. Pharmacol. , vol.11 , pp. 439-445
    • Martinez, J.L.1    Baquero, F.2    Andersson, D.I.3
  • 12
    • 84864386394 scopus 로고    scopus 로고
    • Overproduction of the multidrug efflux pump MexEF-OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in bacterial regulatory networks
    • Olivares J, Alvarez-Ortega C, Linares JF, Rojo F, Kohler T, Martinez JL. 2012. Overproduction of the multidrug efflux pump MexEF-OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in bacterial regulatory networks. Environ. Microbiol. 14:1968-1981. http://dx.doi.org/10.1111/j.1462-2920.2012.02727.x.
    • (2012) Environ. Microbiol. , vol.14 , pp. 1968-1981
    • Olivares, J.1    Alvarez-Ortega, C.2    Linares, J.F.3    Rojo, F.4    Kohler, T.5    Martinez, J.L.6
  • 13
    • 33747154459 scopus 로고    scopus 로고
    • Multidrug-resistance efflux pumps - Not just for resistance
    • DOI 10.1038/nrmicro1464, PII NRMICRO1464
    • Piddock LJ. 2006. Multidrug-resistance efflux pumps - not just for resistance. Nat. Rev. Microbiol. 4:629-636. http://dx.doi.org/10.1038/ nrmicro1464. (Pubitemid 44317025)
    • (2006) Nature Reviews Microbiology , vol.4 , Issue.8 , pp. 629-636
    • Piddock, L.J.V.1
  • 15
    • 84875888798 scopus 로고    scopus 로고
    • RND multidrug efflux pumps: What are they good for?
    • Alvarez-Ortega C, Olivares J, Martinez JL. 2013. RND multidrug efflux pumps: what are they good for? Front. Microbiol. 4:7. http://dx.doi.org/10.3389/ fmicb.2013.00007.
    • (2013) Front. Microbiol. , vol.4 , pp. 7
    • Alvarez-Ortega, C.1    Olivares, J.2    Martinez, J.L.3
  • 16
    • 0031661594 scopus 로고    scopus 로고
    • Influence of the MexAB-OprM multidrug efflux system on quorum sensing in Pseudomonas aeruginosa
    • Evans K, Passador L, Srikumar R, Tsang E, Nezezon J, Poole K. 1998. Influence of the MexAB-OprM multidrug efflux system on quorum sensing in Pseudomonas aeruginosa. J. Bacteriol. 180:5443-5447. (Pubitemid 28471543)
    • (1998) Journal of Bacteriology , vol.180 , Issue.20 , pp. 5443-5447
    • Evans, K.1    Passador, L.2    Srikumar, R.3    Tsang, E.4    Nezezon, J.5    Poole, K.6
  • 17
    • 0034871821 scopus 로고    scopus 로고
    • Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa
    • DOI 10.1128/JB.183.18.5213-5222.2001
    • Köhler T, van Delden C, Curty LK, Hamzehpour MM, Pechere JC. 2001. Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa. J. Bacteriol. 183:5213-5222. http://dx.doi.org/10.1128/JB.183.18.5213-5222.2001. (Pubitemid 32802590)
    • (2001) Journal of Bacteriology , vol.183 , Issue.18 , pp. 5213-5222
    • Kohler, T.1    Van Delden, C.2    Curty, L.K.3    Hamzehpour, M.M.4    Pechere, J.-C.5
  • 19
    • 0141446140 scopus 로고    scopus 로고
    • A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection
    • DOI 10.1128/IAI.71.10.5576-5582.2003
    • Jerse AE, Sharma ND, Simms AN, Crow ET, Snyder LA, Shafer WM. 2003. A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection. Infect. Immun. 71:5576-5582. http://dx.doi.org/10.1128/IAI.71.10.5576-5582.2003. (Pubitemid 37205608)
    • (2003) Infection and Immunity , vol.71 , Issue.10 , pp. 5576-5582
    • Jerse, A.E.1    Sharma, N.D.2    Simms, A.N.3    Crow, E.T.4    Snyder, L.A.5    Shafer, W.M.6
  • 20
    • 0032782869 scopus 로고    scopus 로고
    • The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids
    • DOI 10.1046/j.1365-2958.1999.01530.x
    • Lee EH, Shafer WM. 1999. The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids. Mol. Microbiol. 33:839-845. http://dx.doi.org/10.1046/j.1365-2958.1999.01530.x. (Pubitemid 29392663)
    • (1999) Molecular Microbiology , vol.33 , Issue.4 , pp. 839-845
    • Lee, E.H.1    Shafer, W.M.2
  • 21
    • 0032539553 scopus 로고    scopus 로고
    • Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family
    • DOI 10.1073/pnas.95.4.1829
    • Shafer WM, Qu X, Waring AJ, Lehrer RI. 1998. Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family. Proc. Natl. Acad. Sci. U. S. A. 95:1829-1833. http://dx.doi.org/10.1073/pnas.95.4.1829. (Pubitemid 28103479)
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.4 , pp. 1829-1833
    • Shafer, W.M.1    Qu, X.-D.2    Waring, A.J.3    Lehrer, R.I.4
  • 22
    • 0035183854 scopus 로고    scopus 로고
    • SmeDEF multidrug efflux pump contributes to intrinsic multidrug resistance in Stenotrophomonas maltophilia
    • DOI 10.1128/AAC.45.12.3497-3503.2001
    • Zhang L, Li XZ, Poole K. 2001. SmeDEF multidrug efflux pump contributes to intrinsic multidrug resistance in Stenotrophomonas maltophilia. Antimicrob. Agents Chemother. 45:3497-3503. http://dx.doi.org/10.1128/AAC.45.12.3497-3503. 2001. (Pubitemid 33107868)
    • (2001) Antimicrobial Agents and Chemotherapy , vol.45 , Issue.12 , pp. 3497-3503
    • Zhang, L.1    Li, X.-Z.2    Poole, K.3
  • 25
    • 0031948133 scopus 로고    scopus 로고
    • Antibiotic resistance caused by gram-negative multidrug efflux pumps
    • Nikaido H. 1998. Antibiotic resistance caused by gram-negative multi-drug efflux pumps. Clin. Infect. Dis. 27(Suppl 1):S32-S41. (Pubitemid 28375857)
    • (1998) Clinical Infectious Diseases , vol.27 , Issue.SUPPL.1
    • Nikaido, H.1
  • 26
    • 0028067837 scopus 로고
    • Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: Resistance to tetracycline, chloramphenicol, and norfloxacin
    • Li XZ, Livermore DM, Nikaido H. 1994. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin. Antimicrob. Agents Chemother. 38:1732-1741. http://dx.doi.org/10.1128/AAC.38.8.1732. (Pubitemid 24250718)
    • (1994) Antimicrobial Agents and Chemotherapy , vol.38 , Issue.8 , pp. 1732-1741
    • Li, X.-Z.1    Livermore, D.M.2    Nikaido, H.3
  • 27
    • 0035783036 scopus 로고    scopus 로고
    • Transcriptional regulation of multidrug efflux pumps in bacteria
    • Grkovic S, Brown MH, Skurray RA. 2001. Transcriptional regulation of multidrug efflux pumps in bacteria. Semin. Cell Dev. Biol. 12:225-237. http://dx.doi.org/10.1006/scdb.2000.0248.
    • (2001) Semin. Cell Dev. Biol. , vol.12 , pp. 225-237
    • Grkovic, S.1    Brown, M.H.2    Skurray, R.A.3
  • 28
    • 79959848567 scopus 로고    scopus 로고
    • The binding of triclosan to SmeT, the repressor of the multidrug efflux pump SmeDEF, induces antibiotic resistance in Stenotrophomonas maltophilia
    • Hernandez A, Ruiz FM, Romero A, Martinez JL. 2011. The binding of triclosan to SmeT, the repressor of the multidrug efflux pump SmeDEF, induces antibiotic resistance in Stenotrophomonas maltophilia. PLoS Pathog. 7:e1002103. http://dx.doi.org/10.1371/journal.ppat.1002103.
    • (2011) PLoS Pathog. , vol.7
    • Hernandez, A.1    Ruiz, F.M.2    Romero, A.3    Martinez, J.L.4
  • 29
    • 67649827837 scopus 로고    scopus 로고
    • Structural and functional analysis of SmeT, the repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF
    • Hernandez A, Mate MJ, Sanchez-Diaz PC, Romero A, Rojo F, Martinez JL. 2009. Structural and functional analysis of SmeT, the repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF. J. Biol. Chem. 284:14428-14438. http://dx.doi.org/10.1074/jbc.M809221200.
    • (2009) J. Biol. Chem. , vol.284 , pp. 14428-14438
    • Hernandez, A.1    Mate, M.J.2    Sanchez-Diaz, P.C.3    Romero, A.4    Rojo, F.5    Martinez, J.L.6
  • 30
    • 0037154432 scopus 로고    scopus 로고
    • Transcriptional regulation of mexR, the repressor of Pseudomonas aeruginosa mexAB-oprM multidrug efflux pump
    • DOI 10.1016/S0378-1097(01)00562-6, PII S0378109701005626
    • Sanchez P, Rojo F, Martinez JL. 2002. Transcriptional regulation of mexR, the repressor of Pseudomonas aeruginosa mexAB-oprM multidrug efflux pump. FEMS Microbiol. Lett. 207:63-68. http://dx.doi.org/10.1111/j.1574-6968.2002.tb11029. x. (Pubitemid 34214807)
    • (2002) FEMS Microbiology Letters , vol.207 , Issue.1 , pp. 63-68
    • Sanchez, P.1    Rojo, F.2    Martinez, J.L.3
  • 31
    • 22544461608 scopus 로고    scopus 로고
    • Induction of the mexXY efflux pump in Pseudomonas aeruginosa is dependent on drug-ribosome interaction
    • DOI 10.1128/JB.187.15.5341-5346.2005
    • Jeannot K, Sobel ML, El Garch F, Poole K, Plesiat P. 2005. Induction of the MexXY efflux pump in Pseudomonas aeruginosa is dependent on drug-ribosome interaction. J. Bacteriol. 187:5341-5346. http://dx.doi.org/10.1128/JB.187.15. 5341-5346.2005. (Pubitemid 41022953)
    • (2005) Journal of Bacteriology , vol.187 , Issue.15 , pp. 5341-5346
    • Jeannot, K.1    Sobel, M.L.2    El, G.F.3    Poole, K.4    Plesiat, P.5
  • 32
    • 77954596827 scopus 로고    scopus 로고
    • Mutation of nfxB causes global changes in the physiology and metabolism of Pseudomonas aeruginosa
    • Stickland HG, Davenport PW, Lilley KS, Griffin JL, Welch M. 2010. Mutation of nfxB causes global changes in the physiology and metabolism of Pseudomonas aeruginosa. J. Proteome Res. 9:2957-2967. http://dx.doi.org/10.1021/ pr9011415.
    • (2010) J. Proteome Res. , vol.9 , pp. 2957-2967
    • Stickland, H.G.1    Davenport, P.W.2    Lilley, K.S.3    Griffin, J.L.4    Welch, M.5
  • 33
    • 14544300496 scopus 로고    scopus 로고
    • Overexpression of the multidrug efflux pumps MexCD-OprJ and MexEF-OprN is associated with a reduction of type III secretion in Pseudomonas aeruginosa
    • DOI 10.1128/JB.187.4.1384-1391.2005
    • Linares JF, Lopez JA, Camafeita E, Albar JP, Rojo F, Martinez JL. 2005. Overexpression of the multidrug efflux pumps MexCD-OprJ and MexEF-OprN is associated with a reduction of type III secretion in Pseudomonas aeruginosa. J. Bacteriol. 187:1384-1391. http://dx.doi.org/10.1128/JB.187.4.1384-1391.2005. (Pubitemid 40299463)
    • (2005) Journal of Bacteriology , vol.187 , Issue.4 , pp. 1384-1391
    • Linares, J.F.1    Lopez, J.A.2    Camafeita, E.3    Albar, J.P.4    Rojo, F.5    Martinez, J.L.6
  • 34
    • 80052845657 scopus 로고    scopus 로고
    • Antagonistic interactions of Pseudomonas aeruginosa antibiotic resistance mechanisms in planktonic but not biofilm growth
    • Mulet X, Moya B, Juan C, Macia MD, Perez JL, Blazquez J, Oliver A. 2011. Antagonistic interactions of Pseudomonas aeruginosa antibiotic resistance mechanisms in planktonic but not biofilm growth. Antimicrob. Agents Chemother. 55:4560-4568. http://dx.doi.org/10.1128/AAC.00519-11.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 4560-4568
    • Mulet, X.1    Moya, B.2    Juan, C.3    Macia, M.D.4    Perez, J.L.5    Blazquez, J.6    Oliver, A.7
  • 35
    • 84858331190 scopus 로고    scopus 로고
    • Regulation and function of versatile aerobic and anaerobic respiratory metabolism in Pseudomonas aeruginosa
    • Arai H. 2011. Regulation and function of versatile aerobic and anaerobic respiratory metabolism in Pseudomonas aeruginosa . Front. Microbiol. 2:103. http://dx.doi.org/10.3389/fmicb.2011.00103.
    • (2011) Front. Microbiol. , vol.2 , pp. 103
    • Arai, H.1
  • 36
    • 0026080512 scopus 로고
    • Anaerobically induced expression of the nitrite reductase cytochrome c-551 operon from Pseudomonas aeruginosa
    • Arai H, Igarashi Y, Kodama T. 1991. Anaerobically induced expression of the nitrite reductase cytochrome c-551 operon from Pseudomonas aeruginosa. FEBS Lett. 280:351-353. http://dx.doi.org/10.1016/0014-5793(91)80329-2.
    • (1991) FEBS Lett. , vol.280 , pp. 351-353
    • Arai, H.1    Igarashi, Y.2    Kodama, T.3
  • 37
    • 0025737522 scopus 로고
    • Nitrite activates the transcription of the Pseudomonas aeruginosa nitrite reductase and cytochrome c-551 operon under anaerobic conditions
    • Arai H, Igarashi Y, Kodama T. 1991. Nitrite activates the transcription of the Pseudomonas aeruginosa nitrite reductase and cytochrome c-551 operon under anaerobic conditions. FEBS Lett. 288:227-228. http://dx.doi.org/10.1016/ 0014-5793(91)81040-F.
    • (1991) FEBS Lett. , vol.288 , pp. 227-228
    • Arai, H.1    Igarashi, Y.2    Kodama, T.3
  • 38
    • 0031016991 scopus 로고    scopus 로고
    • Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa
    • Köhler T, Michea-Hamzehpour M, Henze U, Gotoh N, Curty LK, Pechere JC. 1997. Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa. Mol. Microbiol. 23:345-354. http://dx.doi.org/10.1046/j.1365-2958.1997.2281594.x. (Pubitemid 27049187)
    • (1997) Molecular Microbiology , vol.23 , Issue.2 , pp. 345-354
    • Kohler, T.1    Michea-Hamzehpour, M.2    Henze, U.3    Gotoh, N.4    Curty, L.K.5    Pechere, J.-C.6
  • 40
    • 0037378570 scopus 로고    scopus 로고
    • Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: A transcriptome analysis
    • DOI 10.1128/JB.185.7.2066-2079.2003
    • Schuster M, Lostroh CP, Ogi T, Greenberg EP. 2003. Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J. Bacteriol. 185:2066-2079. http://dx.doi.org/10.1128/JB.185.7.2066-2079.2003. (Pubitemid 36363167)
    • (2003) Journal of Bacteriology , vol.185 , Issue.7 , pp. 2066-2079
    • Schuster, M.1    Lostroh, C.P.2    Ogi, T.3    Greenberg, E.P.4
  • 41
    • 0035710746 scopus 로고    scopus 로고
    • -deltadeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-DDCT method. Methods 25:402-408. http://dx.doi.org/10.1006/meth.2001.1262. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 42
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • DOI 10.1016/0378-1119(89)90358-2
    • Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59. http://dx.doi.org/10.1016/0378-1119(89)90358-2. (Pubitemid 19125653)
    • (1989) Gene , vol.77 , Issue.1 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 44
    • 0032575051 scopus 로고    scopus 로고
    • A broad-host-range F1p-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: Application for isolation of unmarked Pseudomonas aeruginosa mutants
    • DOI 10.1016/S0378-1119(98)00130-9, PII S0378111998001309
    • Hoang TT, Karkhoff-Schweizer RR, Kutchma AJ, Schweizer HP. 1998. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212:77-86. http://dx.doi.org/10.1016/S0378- 1119(98)00130-9. (Pubitemid 28269135)
    • (1998) Gene , vol.212 , Issue.1 , pp. 77-86
    • Hoang, T.T.1    Karkhoff-Schweizer, R.R.2    Kutchma, A.J.3    Schweizer, H.P.4
  • 45
    • 0030691171 scopus 로고    scopus 로고
    • Measurement of the intracellular pH in Escherichia coli with the internally conjugated fluorescent probe 5- (and 6-)carboxyfluorescein succinimidyl ester
    • Riondet C, Cachon R, Waché Y, Alcaraz G, Diviès C. 1997. Measurement of the intracellular pH in Escherichia coli with the internally conjugated fluorescent probe 5- (and 6-)carboxyfluorescein succinimidyl ester. Biotechnol. Tech. 11:735-738. http://dx.doi.org/10.1023/A:1018492217623. (Pubitemid 27456619)
    • (1997) Biotechnology Techniques , vol.11 , Issue.10 , pp. 735-738
    • Riondet, C.1    Cachon, R.2    Wache, Y.3    Alcaraz, G.4    Divies, C.5
  • 46
    • 20444459899 scopus 로고    scopus 로고
    • Transcriptional regulation of the flavohemoglobin gene for aerobic nitric oxide detoxification by the second nitric oxide-responsive regulator of Pseudomonas aeruginosa
    • DOI 10.1128/JB.187.12.3960-3968.2005
    • Arai H, Hayashi M, Kuroi A, Ishii M, Igarashi Y. 2005. Transcriptional regulation of the flavohemoglobin gene for aerobic nitric oxide detoxification by the second nitric oxide-responsive regulator of Pseudomonas aeruginosa. J. Bacteriol. 187:3960-3968. http://dx.doi.org/10.1128/JB.187.12.3960-3968.2005. (Pubitemid 40827779)
    • (2005) Journal of Bacteriology , vol.187 , Issue.12 , pp. 3960-3968
    • Arai, H.1    Hayashi, M.2    Kuroi, A.3    Ishii, M.4    Igarashi, Y.5
  • 47
    • 75649127253 scopus 로고    scopus 로고
    • Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa
    • Tian ZX, Fargier E, Mac Aogain M, Adams C, Wang YP, O'Gara F. 2009. Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa. Nucleic Acids Res. 37:7546-7559. http://dx.doi.org/10.1093/nar/gkp828.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 7546-7559
    • Tian, Z.X.1    Fargier, E.2    Mac Aogain, M.3    Adams, C.4    Wang, Y.P.5    O'Gara, F.6
  • 48
    • 70349543968 scopus 로고    scopus 로고
    • MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump
    • Tian ZX, Mac Aogain M, O'Connor HF, Fargier E, Mooij MJ, Adams C, Wang YP, O'Gara F. 2009. MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump. Microb. Pathog. 47:237-241. http://dx.doi.org/10.1016/j.micpath.2009.08.003.
    • (2009) Microb. Pathog. , vol.47 , pp. 237-241
    • Tian, Z.X.1    Mac Aogain, M.2    O'Connor, H.F.3    Fargier, E.4    Mooij, M.J.5    Adams, C.6    Wang, Y.P.7    O'Gara, F.8
  • 49
    • 34250620817 scopus 로고    scopus 로고
    • Responses of Pseudomonas aeruginosa to low oxygen indicate that growth in the cystic fibrosis lung is by aerobic respiration
    • DOI 10.1111/j.1365-2958.2007.05772.x
    • Alvarez-Ortega C, Harwood CS. 2007. Responses of Pseudomonas aeruginosa to low oxygen indicate that growth in the cystic fibrosis lung is by aerobic respiration. Mol. Microbiol. 65:153-165. http://dx.doi.org/10.1111/j.1365-2958. 2007.05772.x. (Pubitemid 46934486)
    • (2007) Molecular Microbiology , vol.65 , Issue.1 , pp. 153-165
    • Alvarez-Ortega, C.1    Harwood, C.S.2
  • 50
    • 0030885697 scopus 로고    scopus 로고
    • Cascade regulation of the two CRP/FNR-related transcriptional regulators (ANR and DNR) and the denitrification enzymes in Pseudomonas aeruginosa
    • Arai H, Kodama T, Igarashi Y. 1997. Cascade regulation of the two CRP/FNR-related transcriptional regulators (ANR and DNR) and the denitrification enzymes in Pseudomonas aeruginosa. Mol. Microbiol. 25:1141-1148. http://dx.doi.org/10.1046/j.1365-2958.1997.5431906.x. (Pubitemid 27410192)
    • (1997) Molecular Microbiology , vol.25 , Issue.6 , pp. 1141-1148
    • Aral, H.1    Kodama, T.2    Igarashi, Y.3
  • 51
    • 1442276329 scopus 로고    scopus 로고
    • 3 cytochrome oxidases
    • 3 cytochrome oxidases. Mol. Microbiol. 51:1193-1203. http://dx.doi.org/10.1046/j.1365-2958.2003.03904.x.
    • (2004) Mol. Microbiol. , vol.51 , pp. 1193-1203
    • Comolli, J.C.1    Donohue, T.J.2
  • 52
    • 33646058024 scopus 로고    scopus 로고
    • Competition between oxygen and nitrate respirations in continuous culture of Pseudomonas aeruginosa performing aerobic denitrification
    • Chen F, Xia Q, Ju LK. 2006. Competition between oxygen and nitrate respirations in continuous culture of Pseudomonas aeruginosa performing aerobic denitrification. Biotechnol. Bioeng. 93:1069-1078. http://dx.doi.org/10.1002/ bit.20812.
    • (2006) Biotechnol. Bioeng. , vol.93 , pp. 1069-1078
    • Chen, F.1    Xia, Q.2    Ju, L.K.3
  • 53
    • 0024980259 scopus 로고
    • Nitrite reductase from Pseudomonas aeruginosa: Sequence of the gene and the protein
    • Silvestrini MC, Galeotti CL, Gervais M, Schinina E, Barra D, Bossa F, Brunori M. 1989. Nitrite reductase from Pseudomonas aeruginosa: sequence of the gene and the protein. FEBS Lett. 254:33-38. http://dx.doi.org/10.1016/0014- 5793(89)81004-X.
    • (1989) FEBS Lett. , vol.254 , pp. 33-38
    • Silvestrini, M.C.1    Galeotti, C.L.2    Gervais, M.3    Schinina, E.4    Barra, D.5    Bossa, F.6    Brunori, M.7
  • 54
    • 78751684152 scopus 로고    scopus 로고
    • mexEF-oprN multidrug efflux operon of Pseudomonas aeruginosa: Regulation by the MexT activator in response to nitrosative stress and chloramphenicol
    • Fetar H, Gilmour C, Klinoski R, Daigle DM, Dean CR, Poole K. 2011. mexEF-oprN multidrug efflux operon of Pseudomonas aeruginosa: regulation by the MexT activator in response to nitrosative stress and chloramphenicol. Antimicrob. Agents Chemother. 55:508-514. http://dx.doi.org/10.1128/AAC.00830- 10.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 508-514
    • Fetar, H.1    Gilmour, C.2    Klinoski, R.3    Daigle, D.M.4    Dean, C.R.5    Poole, K.6
  • 55
    • 34250328344 scopus 로고    scopus 로고
    • Membrane-bound nitrate reductase is required for anaerobic growth in cystic fibrosis sputum
    • DOI 10.1128/JB.00162-07
    • Palmer KL, Brown SA, Whiteley M. 2007. Membrane-bound nitrate reductase is required for anaerobic growth in cystic fibrosis sputum. J. Bacteriol. 189:4449-4455. http://dx.doi.org/10.1128/JB.00162-07. (Pubitemid 46919632)
    • (2007) Journal of Bacteriology , vol.189 , Issue.12 , pp. 4449-4455
    • Palmer, K.L.1    Brown, S.A.2    Whiteley, M.3
  • 56
    • 79957568510 scopus 로고    scopus 로고
    • Structure and mechanism of RND-type multidrug efflux pumps
    • Nikaido H. 2011. Structure and mechanism of RND-type multidrug efflux pumps. Adv. Enzymol. Relat. Areas Mol. Biol. 77:1-60. http://www.ncbi.nlm.nih. gov/pmc/articles/PMC3122131/.
    • (2011) Adv. Enzymol. Relat. Areas Mol. Biol. , vol.77 , pp. 1-60
    • Nikaido, H.1
  • 57
    • 19744368356 scopus 로고    scopus 로고
    • Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa
    • DOI 10.1128/IAI.73.6.3764-3772.2005
    • Filiatrault MJ, Wagner VE, Bushnell D, Haidaris CG, Iglewski BH, Passador L. 2005. Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Infect. Immun. 73:3764-3772. http://dx.doi.org/10.1128/IAI.73.6. 3764-3772.2005. (Pubitemid 40745924)
    • (2005) Infection and Immunity , vol.73 , Issue.6 , pp. 3764-3772
    • Filiatrault, M.J.1    Wagner, V.E.2    Bushnell, D.3    Haidaris, C.G.4    Iglewski, B.H.5    Passador, L.6
  • 60
    • 57349131057 scopus 로고    scopus 로고
    • Influence of the Pseudomonas quinolone signal on denitrification in Pseudomonas aeruginosa
    • Toyofuku M, Nomura N, Kuno E, Tashiro Y, Nakajima T, Uchiyama H. 2008. Influence of the Pseudomonas quinolone signal on denitrification in Pseudomonas aeruginosa. J. Bacteriol. 190:7947-7956. http://dx.doi.org/10.1128/JB.00968-08.
    • (2008) J. Bacteriol. , vol.190 , pp. 7947-7956
    • Toyofuku, M.1    Nomura, N.2    Kuno, E.3    Tashiro, Y.4    Nakajima, T.5    Uchiyama, H.6
  • 61
    • 0029146375 scopus 로고
    • Expression of the nir and nor genes for denitrification of Pseudomonas aeruginosa requires a novel CRP/FNR-related transcriptional regulator, DNR, in addition to ANR
    • Arai H, Igarashi Y, Kodama T. 1995. Expression of the nir and nor genes for denitrification of Pseudomonas aeruginosa requires a novel CRP/FNR-related transcriptional regulator, DNR, in addition to ANR. FEBS Lett. 371:73-76. http://dx.doi.org/10.1016/0014-5793(95)00885-D.
    • (1995) FEBS Lett. , vol.371 , pp. 73-76
    • Arai, H.1    Igarashi, Y.2    Kodama, T.3
  • 63
    • 33749255145 scopus 로고    scopus 로고
    • Oxygen, cyanide and energy generation in the cystic fibrosis pathogen Pseudomonas aeruginosa
    • Williams HD, Zlosnik JE, Ryall B. 2007. Oxygen, cyanide and energy generation in the cystic fibrosis pathogen Pseudomonas aeruginosa. Adv. Microb. Physiol. 52:1-71. http://dx.doi.org/10.1016/S0065-2911(06)52001-6.
    • (2007) Adv. Microb. Physiol. , vol.52 , pp. 1-71
    • Williams, H.D.1    Zlosnik, J.E.2    Ryall, B.3
  • 64
    • 80053030075 scopus 로고    scopus 로고
    • MexEF-OprN efflux pump exports the Pseudomonas quinolone signal (PQS) precursor HHQ (4-hydroxy-2-heptylquinoline)
    • Lamarche MG, Deziel E. 2011. MexEF-OprN efflux pump exports the Pseudomonas quinolone signal (PQS) precursor HHQ (4-hydroxy-2-heptylquinoline). PLoS One 6:e24310. http://dx.doi.org/10.1371/journal.pone.0024310.
    • (2011) PLoS One , vol.6
    • Lamarche, M.G.1    Deziel, E.2
  • 67
    • 0017343370 scopus 로고
    • Energy conservation in chemotrophic anaerobic bacteria
    • Thauer RK, Jungermann K, Decker K. 1977. Energy conservation in chemotrophic anaerobic bacteria. Bacteriol. Rev. 41:100-180. (Pubitemid 8082287)
    • (1977) Bacteriological Reviews , vol.41 , Issue.1 , pp. 100-180
    • Thauer, R.K.1    Jungermann, K.2    Decker, K.3
  • 68
    • 84865735753 scopus 로고    scopus 로고
    • Metabolic regulation analysis of wild-type and arcA mutant Escherichia coli under nitrate conditions using different levels of omics data
    • Toya Y, Nakahigashi K, Tomita M, Shimizu K. 2012. Metabolic regulation analysis of wild-type and arcA mutant Escherichia coli under nitrate conditions using different levels of omics data. Mol. Biosyst. 8:2593-2604. http://dx.doi.org/10.1039/c2mb25069a.
    • (2012) Mol. Biosyst. , vol.8 , pp. 2593-2604
    • Toya, Y.1    Nakahigashi, K.2    Tomita, M.3    Shimizu, K.4
  • 69
    • 34249818178 scopus 로고    scopus 로고
    • The anaerobic regulatory network required for Pseudomonas aeruginosa nitrate respiration
    • DOI 10.1128/JB.00240-07
    • Schreiber K, Krieger R, Benkert B, Eschbach M, Arai H, Schobert M, Jahn D. 2007. The anaerobic regulatory network required for Pseudomonas aeruginosa nitrate respiration. J. Bacteriol. 189:4310-4314. http://dx.doi.org/10.1128/JB. 00240-07. (Pubitemid 46847380)
    • (2007) Journal of Bacteriology , vol.189 , Issue.11 , pp. 4310-4314
    • Schreiber, K.1    Krieger, R.2    Benkert, B.3    Eschbach, M.4    Arai, H.5    Schobert, M.6    Jahn, D.7
  • 70
    • 0032952078 scopus 로고    scopus 로고
    • Effect of nitrogen oxides on expression of the nir and nor genes for denitrification in Pseudomonas aeruginosa
    • DOI 10.1016/S0378-1097(98)00517-5, PII S0378109798005175
    • Arai H, Kodama T, Igarashi Y. 1999. Effect of nitrogen oxides on expression of the nir and nor genes for denitrification in Pseudomonas aeruginosa. FEMS Microbiol. Lett. 170:19-24. http://dx.doi.org/10.1111/j.1574- 6968.1999.tb13350.x. (Pubitemid 29044069)
    • (1999) FEMS Microbiology Letters , vol.170 , Issue.1 , pp. 19-24
    • Arai, H.1    Kodama, T.2    Igarashi, Y.3
  • 72
    • 0035194233 scopus 로고    scopus 로고
    • Environmental selection of antibiotic resistance genes
    • DOI 10.1046/j.1462-2920.2001.00161.x
    • Alonso A, Sanchez P, Martinez JL. 2001. Environmental selection of antibiotic resistance genes. Environ. Microbiol. 3:1-9. http://dx.doi.org/10. 1046/j.1462-2920.2001.00161.x. (Pubitemid 33124629)
    • (2001) Environmental Microbiology , vol.3 , Issue.1 , pp. 1-9
    • Alonso, A.1    Sanchez, P.2    Martinez, J.L.3
  • 74
    • 0021027842 scopus 로고
    • A broad host range mobilization system for in vivo genetic engineering: Transposon mutagenesis in gram negative bacteria
    • Simon R, Priefer U, Puhler A. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria. Nat. Biotech. 1:784-791. (Pubitemid 14239484)
    • (1983) Bio/Technology , vol.1 , Issue.9 , pp. 784-791
    • Simon, R.1    Priefer, U.2    Puhler, A.3


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