메뉴 건너뛰기




Volumn 58, Issue 7, 2014, Pages 3626-3635

Positions and numbers of FKS mutations in Candida albicans selectively influence In Vitro and In Vivo susceptibilities to echinocandin treatment

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANIDULAFUNGIN; CASPOFUNGIN; CICLOPIROX; ECHINOCANDIN; FLUCONAZOLE; ISAVUCONAZOLE; MICAFUNGIN; PLACEBO; POSACONAZOLE; TERBINAFINE; VORICONAZOLE; 1,3-BETA-GLUCAN SYNTHASE; ANTIFUNGAL AGENT; CHITIN; FUNGAL PROTEIN; GLUCOSYLTRANSFERASE;

EID: 84903133610     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00123-14     Document Type: Article
Times cited : (55)

References (38)
  • 1
    • 84891715342 scopus 로고    scopus 로고
    • Invasive candidiasis as a cause of sepsis in the critically ill patient
    • Delaloye J, Calandra T. 2013. Invasive candidiasis as a cause of sepsis in the critically ill patient. Virulence 5:154-162. http://dx.doi.org/10.4161/ viru.26187.
    • (2013) Virulence , vol.5 , pp. 154-162
    • Delaloye, J.1    Calandra, T.2
  • 5
    • 84872044632 scopus 로고    scopus 로고
    • Stepwise development of a homozygous S80P substitution in Fks1p, conferring echinocandin resistance in Candida tropicalis
    • Jensen RH, Johansen HK, Arendrup MC. 2013. Stepwise development of a homozygous S80P substitution in Fks1p, conferring echinocandin resistance in Candida tropicalis. Antimicrob. Agents Chemother. 57:614-617. http://dx.doi.org/10.1128/AAC.01193-12.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , pp. 614-617
    • Jensen, R.H.1    Johansen, H.K.2    Arendrup, M.C.3
  • 6
    • 84882374510 scopus 로고    scopus 로고
    • Rapid emergence of echinocandin resistance in Candida glabrata resulting in clinical and microbiologic failure
    • Lewis JS, Jr, Wiederhold NP, Wickes BL, Patterson TF, Jorgensen JH. 2013. Rapid emergence of echinocandin resistance in Candida glabrata resulting in clinical and microbiologic failure. Antimicrob. Agents Chemother. 57:4559-4561. http://dx.doi.org/10.1128/AAC.01144-13.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , pp. 4559-4561
    • Lewis Jr., J.S.1    Wiederhold, N.P.2    Wickes, B.L.3    Patterson, T.F.4    Jorgensen, J.H.5
  • 7
    • 78751679700 scopus 로고    scopus 로고
    • Candida bloodstream infections: Comparison of species distributions and antifungal resistance patterns in community-onset and nosocomial isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009
    • Pfaller MA, Moet GJ, Messer SA, Jones RN, Castanheira M. 2011. Candida bloodstream infections: comparison of species distributions and antifungal resistance patterns in community-onset and nosocomial isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009. Antimicrob. Agents Chemother. 55:561-566. http://dx.doi.org/10.1128/AAC.01079-10.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 561-566
    • Pfaller, M.A.1    Moet, G.J.2    Messer, S.A.3    Jones, R.N.4    Castanheira, M.5
  • 8
    • 84055199809 scopus 로고    scopus 로고
    • Antifungal drug resistance: Mechanisms, epidemiology, and consequences for treatment
    • Pfaller MA. 2012. Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment. Am. J. Med. 125(1 Suppl):S3-S13. http://dx.doi.org/10.1016/j.amjmed.2011.10.001.
    • (2012) Am. J. Med. , vol.125 , Issue.1 SUPPL.
    • Pfaller, M.A.1
  • 9
    • 84880631469 scopus 로고    scopus 로고
    • Echinocandin and triazole antifungal susceptibility profiles for clinical opportunistic yeast and mold isolates collected from 2010 to 2011: Application of new CLSI clinical breakpoints and epidemiological cutoff values for characterization of geographic and temporal trends of antifungal resistance
    • Pfaller MA, Messer SA, Woosley LN, Jones RN, Castanheira M. 2013. Echinocandin and triazole antifungal susceptibility profiles for clinical opportunistic yeast and mold isolates collected from 2010 to 2011: application of new CLSI clinical breakpoints and epidemiological cutoff values for characterization of geographic and temporal trends of antifungal resistance. J. Clin. Microbiol. 51:2571-2581. http://dx.doi.org/10.1128/JCM.00308-13.
    • (2013) J. Clin. Microbiol. , vol.51 , pp. 2571-2581
    • Pfaller, M.A.1    Messer, S.A.2    Woosley, L.N.3    Jones, R.N.4    Castanheira, M.5
  • 10
    • 34447105864 scopus 로고    scopus 로고
    • Resistance to echinocandin-class antifungal drugs
    • DOI 10.1016/j.drup.2007.04.002, PII S1368764607000404
    • Perlin DS. 2007. Resistance to echinocandin-class antifungal drugs. Drug Resist. Updat. 10:121-130. http://dx.doi.org/10.1016/j.drup.2007.04.002. (Pubitemid 47031054)
    • (2007) Drug Resistance Updates , vol.10 , Issue.3 , pp. 121-130
    • Perlin, D.S.1
  • 12
    • 84869203438 scopus 로고    scopus 로고
    • Fks1 and Fks2 are functionally redundant but differentially regulated in Candida glabrata: Implications for echinocandin resistance
    • Katiyar SK, Alastruey-Izquierdo A, Healey KR, Johnson ME, Perlin DS, Edlind TD. 2012. Fks1 and Fks2 are functionally redundant but differentially regulated in Candida glabrata: implications for echinocandin resistance. Antimicrob. Agents Chemother. 56:6304-6309. http://dx.doi.org/10.1128/AAC.00813- 12.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 6304-6309
    • Katiyar, S.K.1    Alastruey-Izquierdo, A.2    Healey, K.R.3    Johnson, M.E.4    Perlin, D.S.5    Edlind, T.D.6
  • 14
    • 84887386047 scopus 로고    scopus 로고
    • Candida and candidaemia. Susceptibility and epidemiology
    • Arendrup MC. 2013. Candida and candidaemia. Susceptibility and epidemiology. Dan. Med. J. 60:B4698.
    • (2013) Dan. Med. J. , vol.60
    • Arendrup, M.C.1
  • 16
    • 33845648995 scopus 로고    scopus 로고
    • Successful treatment of azole-resistant chronic mucocutaneous candidosis with caspofungin [12]
    • DOI 10.2340/00015555-0165
    • Jayasinghe M, Schmidt S, Walker B, Röcken M, Schaller M. 2006. Successful treatment of azole-resistant chronic mucocutaneous candidosis with caspofungin. Acta Derm. Venereol. 86:563-564. http://dx.doi.org/10.2340/ 00015555-0165. (Pubitemid 44950761)
    • (2006) Acta Dermato-Venereologica , vol.86 , Issue.6 , pp. 563-564
    • Jayasinghe, M.1    Schmidt, S.2    Walker, B.3    Rocken, M.4    Schaller, M.5
  • 18
    • 80052593593 scopus 로고    scopus 로고
    • Epidemiological characteristics of Candida species colonizing oral and rectal sites of Jordanian infants
    • Issa SY, Badran EF, Aqel KF, Shehabi AA. 2011. Epidemiological characteristics of Candida species colonizing oral and rectal sites of Jordanian infants. BMC Pediatr. 11:79. http://dx.doi.org/10.1186/1471-2431-11-79.
    • (2011) BMC Pediatr , vol.11 , pp. 79
    • Issa, S.Y.1    Badran, E.F.2    Aqel, K.F.3    Shehabi, A.A.4
  • 19
    • 0031450505 scopus 로고    scopus 로고
    • Development and verification of fingerprinting probes for Candida glabrata
    • Lockhart SR, Joly S, Pujol C, Sobel JD, Pfaller MA, Soll DR. 1997. Development and verification of fingerprinting probes for Candida glabrata. Microbiology 143:3733-3746. http://dx.doi.org/10.1099/00221287-143-12-3733. (Pubitemid 28004606)
    • (1997) Microbiology , vol.143 , Issue.12 , pp. 3733-3746
    • Lockhart, S.R.1    Joly, S.2    Pujol, C.3    Sobel, J.D.4    Pfaller, M.A.5    Soll, D.R.6
  • 20
    • 0041342964 scopus 로고    scopus 로고
    • Characterization of yeast isolates originating from Hungarian dairy products using traditional and molecular identification techniques
    • DOI 10.1016/S0168-1605(03)00251-4
    • Vasdinyei R, Deák T. 2003. Characterization of yeast isolates originating from Hungarian dairy products using traditional and molecular identification techniques. Int. J. Food Microbiol. 86:123-130. http://dx.doi.org/10.1016/S0168-1605(03)00251-4. (Pubitemid 36900411)
    • (2003) International Journal of Food Microbiology , vol.86 , Issue.1-2 , pp. 123-130
    • Vasdinyei, R.1    Deak, T.2
  • 21
    • 84862606187 scopus 로고    scopus 로고
    • EUCAST technical note on the EUCAST definitive document EDef 7.2: Method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST)
    • EUCAST-AFST
    • Arendrup MC, Cuenca-Estrella M, Lass-Flörl C, Hope W, EUCAST-AFST. 2012. EUCAST technical note on the EUCAST definitive document EDef 7.2: method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST). Clin. Microbiol. Infect. 18:E246-E247. http://dx.doi.org/10.1111/j.1469-0691.2012.03880.x.
    • (2012) Clin. Microbiol. Infect. , vol.18
    • Arendrup, M.C.1    Cuenca-Estrella, M.2    Lass-Flörl, C.3    Hope, W.4
  • 22
    • 84900467753 scopus 로고    scopus 로고
    • EUCAST technical note on Candida and micafungin, anidulafungin and fluconazole
    • European Committee on Antimicrobial Susceptibility Testing-Subcommittee on Antifungal Susceptibility Testing (EUCAST-AFST)
    • Arendrup MC, Cuenca-Estrella M, Lass-Flörl C, Hope WW, European Committee on Antimicrobial Susceptibility Testing-Subcommittee on Antifungal Susceptibility Testing (EUCAST-AFST). 2013. EUCAST technical note on Candida and micafungin, anidulafungin and fluconazole. Mycoses 17:18-20. http://dx.doi.org/10.1111/myc.12170.
    • (2013) Mycoses , vol.17 , pp. 18-20
    • Arendrup, M.C.1    Cuenca-Estrella, M.2    Lass-Flörl, C.3    Hope, W.W.4
  • 23
    • 59749090444 scopus 로고    scopus 로고
    • Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: Implications for interpretive breakpoints
    • Garcia-Effron G, Park S, Perlin DS. 2009. Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints. Antimicrob. Agents Chemother. 53:112-122. http://dx.doi.org/10.1128/AAC.01162-08.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 112-122
    • Garcia-Effron, G.1    Park, S.2    Perlin, D.S.3
  • 24
    • 5044225522 scopus 로고    scopus 로고
    • The SAT1 flipper, an optimized tool for gene disruption in Candida albicans
    • DOI 10.1016/j.gene.2004.06.021, PII S0378111904003555
    • Reuss O, Vik A, Kolter R, Morschhäuser J. 2004. The SAT1 flipper, an optimized tool for gene disruption in Candida albicans. Gene 341:119-127. http://dx.doi.org/10.1016/j.gene.2004.06.021. (Pubitemid 39335889)
    • (2004) Gene , vol.341 , Issue.1-2 , pp. 119-127
    • Reuss, O.1    Vik, A.2    Kolter, R.3    Morschhauser, J.4
  • 25
    • 0021742042 scopus 로고
    • Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S.cerevisiae ura3 and E. coli pyrF mutations
    • DOI 10.1007/BF00328721
    • Gillum AM, Tsay EY, Kirsch DR. 1984. Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol. Gen. Genet. 198:179-182. http://dx.doi.org/10.1007/BF00328721. (Pubitemid 15180998)
    • (1984) Molecular and General Genetics , vol.198 , Issue.1 , pp. 179-182
    • Gillum, A.M.1    Tsay, E.Y.H.2    Kirsch, D.R.3
  • 26
    • 84860187010 scopus 로고    scopus 로고
    • Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations
    • Arendrup MC, Perlin DS, Jensen RH, Howard SJ, Goodwin J, Hope W. 2012. Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations. Antimicrob. Agents Chemother. 56:2435-2442. http://dx.doi.org/10.1128/AAC.06369- 11.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 2435-2442
    • Arendrup, M.C.1    Perlin, D.S.2    Jensen, R.H.3    Howard, S.J.4    Goodwin, J.5    Hope, W.6
  • 28
    • 84862513977 scopus 로고    scopus 로고
    • Caspofungin Etest susceptibility testing of Candida species: Risk of misclassification of susceptible isolates of C. Glabrata and C. Krusei when adopting the revised CLSI caspofungin breakpoints
    • Danish Fungaemia Study Group
    • Arendrup MC, Pfaller MA, Danish Fungaemia Study Group. 2012. Caspofungin Etest susceptibility testing of Candida species: risk of misclassification of susceptible isolates of C. glabrata and C. krusei when adopting the revised CLSI caspofungin breakpoints. Antimicrob. Agents Chemother. 56:3965-3968. http://dx.doi.org/10.1128/AAC.00355-12.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 3965-3968
    • Arendrup, M.C.1    Pfaller, M.A.2
  • 29
    • 84860187010 scopus 로고    scopus 로고
    • Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations
    • Arendrup MC, Perlin DS, Jensen RH, Howard SJ, Goodwin J, Hope W. 2012. Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations. Antimicrob. Agents Chemother. 56:2435-2442. http://dx.doi.org/10.1128/AAC.06369- 11.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 2435-2442
    • Arendrup, M.C.1    Perlin, D.S.2    Jensen, R.H.3    Howard, S.J.4    Goodwin, J.5    Hope, W.6
  • 33
    • 70049109583 scopus 로고    scopus 로고
    • Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin
    • Singh SD, Robbins N, Zaas AK, Schell WA, Perfect JR, Cowen LE. 2009. Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. PLoS Pathog. 5:e1000532. http://dx.doi.org/10.1371/journal. ppat.1000532.
    • (2009) PLoS Pathog. , vol.5
    • Singh, S.D.1    Robbins, N.2    Zaas, A.K.3    Schell, W.A.4    Perfect, J.R.5    Cowen, L.E.6
  • 34
    • 0344406822 scopus 로고    scopus 로고
    • The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin
    • DOI 10.1046/j.1365-2958.2003.03430.x
    • Schuetzer-Muehlbauer M, Willinger B, Krapf G, Enzinger S, Presterl E, Kuchler K. 2003. The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin. Mol. Microbiol. 48:225-235. http://dx.doi.org/10.1046/j.1365-2958.2003.03430.x. (Pubitemid 36411479)
    • (2003) Molecular Microbiology , vol.48 , Issue.1 , pp. 225-235
    • Schuetzer-Muehlbauer, M.1    Willinger, B.2    Krapf, G.3    Enzinger, S.4    Presterl, E.5    Kuchler, K.6
  • 36
    • 79960884598 scopus 로고    scopus 로고
    • Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance
    • Ben-Ami R, Garcia-Effron G, Lewis RE, Gamarra S, Leventakos K, Perlin DS, Kontoyiannis DP. 2011. Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance. J. Infect. Dis. 204:626-635. http://dx.doi.org/10.1093/infdis/jir351.
    • (2011) J. Infect. Dis. , vol.204 , pp. 626-635
    • Ben-Ami, R.1    Garcia-Effron, G.2    Lewis, R.E.3    Gamarra, S.4    Leventakos, K.5    Perlin, D.S.6    Kontoyiannis, D.P.7
  • 37
    • 84858252541 scopus 로고    scopus 로고
    • Resistance to echinocandins comes at a cost: The impact of FKS1 hotspot mutations on Candida albicans fitness and virulence
    • Ben-Ami R, Kontoyiannis DP. 2012. Resistance to echinocandins comes at a cost: the impact of FKS1 hotspot mutations on Candida albicans fitness and virulence. Virulence 3:95-97. http://dx.doi.org/10.4161/viru.3.1.18886.
    • (2012) Virulence , vol.3 , pp. 95-97
    • Ben-Ami, R.1    Kontoyiannis, D.P.2
  • 38
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: Is it possible to reverse resistance?
    • Andersson DI, Hughes D. 2010. Antibiotic resistance and its cost: is it possible to reverse resistance? Nat. Rev. Microbiol. 8:260-271. http://dx.doi.org/10.1038/nrmicro2319.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.