In Vivo Characterization of the Biodistribution Profile of Amphipol A8–35

Journal of Membrane Biology

Volumn 247, Issue 9-10, 2014, Pages 1043-1051

  Fernandez, A ^a   Le Bon, C ^b   Baumlin, N ^a   Giusti, F ^b   Cremel G ^a   Popot, J L ^b   Bagnard, D ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b CNRS   (France)

Author keywords

Membrane proteins; Obesity; Polymers; Surfactants; Vaccination; Vectorization

Indexed keywords

ALEXA FLUOR 647; AMPHIPOL A8 35; DYE; POLYACRYLIC ACID; RHODAMINE; UNCLASSIFIED DRUG; AMPHIPOL A8-35; POLYMER; PROPYLAMINE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELIMINATION REACTION; EX VIVO STUDY; FEMALE; FLUORESCENCE IMAGING; IN VIVO STUDY; LATENT PERIOD; MOUSE; MULTICENTER STUDY (TOPIC); NONHUMAN; PERITONEAL CAVITY; SPLEEN; SYNTHESIS; ADIPOSE TISSUE; ANIMAL; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; DRUG DELIVERY SYSTEM; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLIC CLEARANCE RATE; METABOLISM; NUDE MOUSE; PHYSIOLOGY; SUBCUTANEOUS DRUG ADMINISTRATION; TISSUE DISTRIBUTION;

ADIPOSE TISSUE; ANIMALS; DRUG DELIVERY SYSTEMS; FEMALE; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED BALB C; MICE, NUDE; ORGAN SPECIFICITY; POLYMERS; PROPYLAMINES; TISSUE DISTRIBUTION;

EID: 84903124448     PISSN: 00222631     EISSN: 14321424     Source Type: Journal    
DOI: 10.1007/s00232-014-9682-8     Document Type: Article

References (22)

1. Blankson H, Stakkestad JA, Fagertun H, Thom E, Wadstein J, Gudmundsen O (2000) Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J Nutr 130:2943–2948
2. Charvolin D, Perez J-B, Rouvière F, Giusti F, Bazzacco P, Abdine A, Rappaport F, Martinez KL, Popot J-L (2009) The use of amphipols as universal molecular adapters to immobilize membrane proteins onto solid supports. Proc Natl Acad Sci USA 106:405–410
3. Destouches D, Page N, Hamma-Kourbali Y, Machi V, Chaloin O, Frechault S, Birmpas C, Katsoris P, Beyrath J, Albanese P, Maurer M, Carpentier G, Strub J-M, Van Dorsselaer A, Muller S, Bagnard D, Briand JP, Courty J (2011) A simple approach to cancer therapy afforded by multivalent pseudopeptides that target cell-surface nucleoproteins. Cancer Res 71:3296–3305
4. Ding H, Wu F (2012) Image guided biodistribution and pharmacokinetic studies of theranostics. Theranostics 2:1040–1053
5. Giusti F, Popot J-L, Tribet C (2012) Well-defined critical association concentration and rapid adsorption at the air/water interface of a short amphiphilic polymer, amphipol A8–35: a study by Förster resonance energy transfer and dynamic surface tension measurements. Langmuir 28:10372–10380
6. Gohon Y, Pavlov G, Timmins P, Tribet C, Popot J-L, Ebel C (2004) Partial specific volume and solvent interactions of amphipol A8–35. Anal Biochem 334:318–334
7. Gohon Y, Giusti F, Prata C, Charvolin D, Timmins P, Ebel C, Tribet C, Popot J-L (2006) Well-defined nanoparticles formed by hydrophobic assembly of a short and polydisperse random terpolymer, amphipol A8–35. Langmuir 22:1281–1290
8. Kim D, Park J-H, Kweon D-J, Han GD (2013) Bioavailability of nanoemulsified conjugated linoleic acid for an antiobesity effect. Int J Nanomed 8:451–459
9. Lai CP, Mardini O, Ericsson M, Prabhakar S, Maguire CA, Chen JW, Tannous BA, Breakefield XO (2014) Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter. ACS Nano 8:483–594
10. Le Bon C, Popot J-L, Giusti F (2014) Labeling and functionalizing amphipols for biological applications. J Membr Biol. doi:10.1007/s00232-014-9655-y
11. Nasarre C, Roth M, Jacob L, Roth L, Koncina E, Thien A, Labourdette G, Poulet P, Hubert P, Crémel G, Roussel G, Aunis D, Bagnard D (2010) Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo. Oncogene 29:2381–2392
12. Page N, Gros F, Schall N, Décossas M, Bagnard D, Briand J-P, Muller S (2011) HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus. Ann Rheum Dis 70:837–843
13. Popot J-L, Berry EA, Charvolin D, Creuzenet C, Ebel C, Engelman DM, Flötenmeyer M, Giusti F, Gohon Y, Hervé P, Hong Q, Lakey JH, Leonard K, Shuman HA, Timmins P, Warschawski DE, Zito F, Zoonens M, Pucci B, Tribet C (2003) Amphipols: polymeric surfactants for membrane biology research. Cell Mol Life Sci 60:1559–1574
14. Popot J-L, Althoff T, Bagnard D, Banères J-L, Bazzacco P, Billon-Denis E, Catoire LJ, Champeil P, Charvolin D, Cocco MJ, Crémel G, Dahmane T, de la Maza LM, Ebel C, Gabel F, Giusti F, Gohon Y, Goormaghtigh E, Guittet E, Kleinschmidt JH, Kühlbrandt W, Le Bon C, Martinez KL, Picard M, Pucci B, Rappaport F, Sachs JN, Tribet C, van Heijenoort C, Wien F, Zito F, Zoonens M (2011) Amphipols from A to Z. Annu Rev Biophys 40:379–408
15. Schoellhammer CM, Blankschtein D, Langer R (2014) Skin permeabilization for transdermal drug delivery: recent advances and future prospects. Expert Opin Drug Deliv 11:393–407
16. Tifrea DF, Sun G, Pal S, Zardeneta G, Cocco MJ, Popot J-L, de la Maza LM (2011) Amphipols stabilize the Chlamydia major outer membrane protein and enhance its protective ability as a vaccine. Vaccine 29:4623–4631
17. Tifrea D, Pal S, Cocco MJ, Popot J-L, de la Maza LM (2014) Increased immuno accessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with C. muridarum. J Immunol 192(11):5201–5213
18. Tribet C, Audebert R, Popot J-L (1996) Amphipols: polymers that keep membrane proteins soluble in aqueous solutions. Proc Natl Acad Sci USA 93:15047–15050
19. Tribet C, Audebert R, Popot J-L (1997) Stabilization of hydrophobic colloidal dispersions in water with amphiphilic polymers: application to integral membrane proteins. Langmuir 13:5570–5576
20. Tribet C, Diab C, Dahmane T, Zoonens M, Popot J-L, Winnik FM (2009) Thermodynamic characterization of the exchange of detergents and amphipols at the surfaces of integral membrane proteins. Langmuir 25:12623–12634
21. Zoonens M, Popot J-L (2014) Amphipols for each season. J Membrane Biol. doi:10.1007/s00232-014-9666-8
22. Zoonens M, Giusti F, Zito F, Popot J-L (2007) Dynamics of membrane protein/amphipol association studied by Förster resonance energy transfer. Implications for in vitro studies of amphipol-stabilized membrane proteins. Biochemistry 46:10392–10404