Tissue plasminogen activator promotes postischemic neutrophil recruitment via its proteolytic and nonproteolytic properties

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 7, 2014, Pages 1495-1504

  Uhl, Bernd ^a   Zuchtriegel, Gabriele ^a,b   Puhr Westerheide, Daniel ^a   Praetner, Marc ^a   Rehberg, Markus ^a   Fabritius, Matthias ^a   Hessenauer, Maximilian ^a,b   Holzer, Martin ^a,b   Khandoga, Andrej ^a   Fürst, Robert ^b,c   Zahler, Stefan ^b   Krombach, Fritz ^a   Reichel, Christoph A ^a,b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

fibrinolysis; inflammation; leukocytes; microvascular permeability; neutrophils; reperfusion injury; tissue plasminogen activator

Indexed keywords

ALTEPLASE; FIBRINOGEN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GELATINASE; L SELECTIN; MUTANT PROTEIN; PLASMIN; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; BLOOD VESSEL WALL; CELL TRANSFER; CONTROLLED STUDY; CREMASTER MUSCLE; ENDOTHELIUM CELL; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE; LEUKOCYTE ACTIVATION; LEUKOCYTE ROLLING; MAST CELL; MEDIATOR RELEASE; MICROVASCULAR ISCHEMIA; MICROVASCULATURE; MOUSE; MUSCLE ISCHEMIA; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; REPERFUSION INJURY; TRANSCELLULAR CELL MIGRATION;

FIBRINOLYSIS; INFLAMMATION; LEUKOCYTES; MICROVASCULAR PERMEABILITY; NEUTROPHILS; REPERFUSION INJURY; TISSUE PLASMINOGEN ACTIVATOR;

ANIMALS; CAPILLARY PERMEABILITY; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FIBRINOGEN; FIBRINOLYSIN; GELATINASES; HEMODYNAMICS; HUMANS; MALE; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROCIRCULATION; MICROVESSELS; MUSCLES; MUTATION; NEUTROPHIL INFILTRATION; NEUTROPHILS; RECOMBINANT PROTEINS; REPERFUSION INJURY; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

EID: 84903122663     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303721     Document Type: Article

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