Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease

Journal of Clinical Investigation

Volumn 124, Issue 7, 2014, Pages 2947-2962

  Knowles, Byron C ^a   Roland, Joseph T ^a   Krishnan, Moorthy ^a   Tyska, Matthew J ^a   Lapierre, Lynne A ^a   Dickman, Paul S ^b,c   Goldenring, James R ^a,d,e   Shub, Mitchell D ^b,c,e  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PHOENIX CHILDREN'S HOSPITAL   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BETA CATENIN; F ACTIN; MYOSIN V; MYOSIN VB; PHALLOIDIN; PROTEIN CDC42; PROTEIN KINASE C; PROTEIN P120; RAB PROTEIN; RAB11 PROTEIN; RAB11A PROTEIN; RAB8A PROTEIN; SODIUM GLUCOSE COTRANSPORTER 1; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; BIOTINYLATION; CELL MIGRATION; CELL POLARITY; CONTROLLED STUDY; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERNALIZATION; INTESTINE BRUSH BORDER; INTESTINE CELL; MICROVILLUS INCLUSION DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SMALL INTESTINE DISEASE; TIGHT JUNCTION;

CACO-2 CELLS; ENTEROCYTES; GENE KNOCKDOWN TECHNIQUES; HUMANS; INDIANS, NORTH AMERICAN; INFANT; MALABSORPTION SYNDROMES; MICROVILLI; MUCOLIPIDOSES; MUTATION; MYOSIN HEAVY CHAINS; MYOSIN TYPE V; RAB GTP-BINDING PROTEINS; RNA, SMALL INTERFERING;

EID: 84902992066     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI71651     Document Type: Article

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