Evidence for the effectiveness of walking training on walking and self-care after stroke: A systematic review and meta-analysis of randomized controlled trials

Journal of Rehabilitation Medicine

Volumn 46, Issue 5, 2014, Pages 387-399

  Peurala, Sinikka H ^a,d   Karttunen, Auli H ^b   Sjögren, Tuulikki ^b   Paltamaa, Jaana ^c   Heinonen, Ari ^b  

^a Validia Rehabilitation Helsinki   (Finland)

^b UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^c JAMK UNIVERSITY OF APPLIED SCIENCES   (Finland)

^d Validia Rehabilitation Lahti   (Finland)

Author keywords

Disability and health; International classification of functioning; Outcome measures; Recovery of function; Rehabilitation; Stroke; Walking

Indexed keywords

ADULT; AGED; CEREBROVASCULAR ACCIDENT; FEMALE; HUMAN; MALE; META ANALYSIS; MIDDLE AGED; PHYSIOTHERAPY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SELF CARE; WALKING;

ADULT; AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; PHYSICAL THERAPY MODALITIES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SELF CARE; STROKE; WALKING;

EID: 84902985156     PISSN: 16501977     EISSN: None     Source Type: Journal    
DOI: 10.2340/16501977-1805     Document Type: Article

References (123)

1. Jorgensen H, Nakayama H, Raaschou H, Olsen TS. Stroke. Neurologic and functional recovery the Copenhagen stroke study. Phys Med Rehabil Clin N Am 1999; 10: 887-906.
2. Kwakkel G, Wagenaar RC, Koelman TW, Lankhorst GJ, Koetsier JC. Effects of intensity of rehabilitation after stroke. A research synthesis. Stroke 1997; 28: 1550-1556.
3. Langhorne P, Dennis M, Kalra L, Shepperd S, Wade DT, Wolfe CD. Withdrawn: Services for helping acute stroke patients avoid hospital admission. Cochrane Database Syst Rev 2012; 1: CD000444.
4. Van Peppen RP, Kwakkel G, Wood-Dauphinee S, Hendriks HJ, Van der Wees PJ, Dekker J. The impact of physical therapy on functional outcomes after stroke: what's the evidence? Clin Rehabil 2004; 18: 833-862.
5. Kwakkel G, Kollen B, Twisk J. Impact of time on improvement of outcome after stroke. Stroke 2006; 37: 2348-2353.
6. Kwakkel G, Wagenaar RC, Twisk JW, Lankhorst GJ, Koetsier JC. Intensity of leg and arm training after primary middle-cerebralartery stroke: a randomised trial. Lancet 1999; 354: 191-196.
7. Jantra P, Monga TN, Press JM, Gervais BJ. Management of apraxic gait in a stroke patient. Arch Phys Med Rehabil 1992; 73: 95-97.
8. Ada L, Dean CM, Hall JM, Bampton J, Crompton S. A treadmill and overground walking program improves walking in persons residing in the community after stroke: A placebo-controlled, randomized trial. Arch Phys Med Rehabil 2003; 84: 1486-1491.
9. Schauer M, Mauritz K. Musical motor feedback (MMF) in walking hemiparetic stroke patients: randomized trials of gait improvement. Clin Rehabil 2003; 17: 713-722.
10. Pomeroy VM, King LM, Pollock A, Baily-Hallam A, Langhorne P. Electrostimulation for promoting recovery of movement or functional ability after stroke. Cochrane Database Syst Rev 2006: 003241.
11. Hesse S, Bertelt C, Schaffrin A, Malezic M, Mauritz KH. Restoration of gait in nonambulatory hemiparetic patients by treadmill training with partial body-weight support. Arch Phys Med Rehabil 1994; 75: 1087-1093.
12. Malouin F, Potvin M, Prévost J, Richards CL, Wood-Dauphinee S. Use of an intensive task-oriented gait training program in a series of patients with acute cerebrovascular accidents. Phys Ther 1992; 72: 781-789.
13. Moseley AM, Stark A, Cameron ID, Pollock A. Treadmill training and body weight support for walking after stroke. Cochrane Database Syst Rev 2005; (4): CD002840.
14. Colombo G, Joerg M, Schreier R, Dietz V. Tread-mill training of paraplegic patients using a robotic orthosis. J Rehabil Res Dev 2000; 37: 693-700.
15. Hesse S, Uhlenbrock D. A mechanized gait trainer for restoration of gait. J Rehabil Res Dev 2000; 37: 701-708.
16. Mehrholz J, Werner C, Kugler J, Pohl M. Electromechanical-assisted training for walking after stroke. Cochrane Database Syst Rev 2007; (4): CD006185.
17. Hesse S, Waldner A, Tomelleri C. Innovative gait robot for the repetitive practice of floor walking and stair climbing up and down in stroke patients. J Neuroeng Rehabil 2010; 7: 30.
18. Dickstein R. Rehabilitation of gait speed after stroke: a critical review of intervention appraoaches. Neurorehabil Neural Repair 2008: 22; 649-660.
19. International Classification of Functioning, Disability and Health (ICF). World Health Organization: Geneva; 2001. Available from: http://apps.who.int/classifications/icfbrowser/.
20. Cieza A, Geyh S, Chatterji S, Kostanjsek N, Ustün B, Stucki G. ICF linking rules: an update based on lessons learned. J Rehabil Med 2005; 37: 212-218.
21. Salter K, Jutai JW, Teasell R, Foley NC, Bitensky J, Bayley M. Issues for selection of outcome measures in stroke rehabilitation: ICF activity. Disabil Rehabil 2005; 27: 315-340.
22. Salter K, Jutai JW, Teasell R, Foley NC, Bitensky J, Bayley M. Issues for selection of outcome measures in stroke rehabilitation: ICF Participation. Disabil Rehabil 2005; 27: 507-28.
23. Salter KL, Foley NC, Jutai JW, Teasell RW. Assessment of participation outcomes in randomized controlled trials of stroke rehabilitation interventions. Int J Rehabil Res 2007; 30: 339-342.
24. Paltamaa J, Karhula M, Suomela-Markkanen T, Autti-Rämö I, eds. Basis of a good rehabilitation practice. From analysis of current practice and evidence to recommendations. A rehabilitation development project for severely disabled persons. Helsinki: Kela; 2011. Available from: https://helda.helsinki.fi/handle/10138/24581.
25. van Tulder M, Furlan A, Bombardier C, Bouter L, Editorial Board of the Cochrane Collaboration Back Review Group. Updated method guidelines for systematic reviews in the Cochrane Collaboration Back Review Group. Spine 2003; 28: 1290-1299.
26. Anttila H. Evidence-based perspective on CP rehabilitation -reviews on physiotherapy, physiotherapy-related motor-based interventions and orthotic devices (Research Report 180). Helsinki: University of Helsinki; 2008.
27. Salter K, Jutai JW, Teasell R, Foley NC, Bitensky J, Bayley M. Issues for selection of outcome measures in stroke rehabilitation: ICF activity. Disabil Rehabil 2005; 27: 315-40. .
28. The Finnish Medical Society Duodecim. Guidelines for evidence-base medicine work groups. Helsinki: The Finnish Medical Society Duodecim; 2008.
29. Laufer Y, Dickstein R, Chefez Y, Marcovitz E. The effect of treadmill training on the ambulation of stroke survivors in the early stages of rehabilitation: a randomized study. J Rehabil Res Dev 2001; 38: 69-78.
30. Liston R, Mickelborough J, Harris B, Hann A, Tallis R. Conventional physiotherapy and treadmill re-training for higher-level gait disorders in cerebrovascular disease. Age Ageing 2000; 29: 311-318.
31. Cozean C, Pease W, Hubbell S. Biofeedback and functional electric stimulation in stroke rehabilitation. Arch Phys Med Rehabil 1988; 69: 401-405.
32. Ivey FM, Ryan AS, Hafer-Macko CE, Goldberg AP, Macko RF. Treadmill aerobic training improves glucose tolerance and indices of insulin sensitivity in disabled stroke survivors: a preliminary report. Stroke 2007; 38: 2752-2758.
33. Intiso D, Santilli V, Grasso M, Rossi R, Caruso I. Rehabilitation of walking with electromyographic biofeedback in foot- drop after stroke. Stroke 1994; 25: 1189-1192.
34. Kottink AI, Hermens HJ, Nene AV, Tenniglo MJ, van der Aa HE, Buschman HP, et al. A randomized controlled trial of an implantable 2-channel peroneal nerve stimulator on walking speed and activity in poststroke hemiplegia. Arch Phys Med Rehabil 2007; 88: 971-978.
35. Lord S, McPherson KM, McNaughton HK, Rochester L, Weatherall M. How feasible is the attainment of community ambulation after stroke? A pilot randomized controlled trial to evaluate community-based physiotherapy in subacute stroke. Clin Rehabil 2008; 22: 215-225.
36. Richards C, Malouin F, Wood-Dauphinee S, Williams J, Bouchard J, Brunet D. Task-specific physical therapy for optimization of gait recovery in acute stroke patients. Arch Phys Med Rehabil 1993; 74: 612-620.
37. Bogataj U, Gros N, Kljajic M, Acimovic R, Malezic M. The rehabilitation of gait in patients with hemiplegia: a comparison between conventional therapy and multichannel functional electrical stimulation therapy. Phys Ther 1995; 75: 490-502.
38. Kottink AI, Hermens HJ, Nene AV, Tenniglo MJ, Groothuis-Oudshoorn CG, IJzerman MJ. Therapeutic effect of an implantable peroneal nerve stimulator in subjects with chronic stroke and footdrop: a randomized controlled trial. Phys Ther 2008; 88: 437-448.
39. Burridge J, Taylor P, Hagan S, Wood D, Swain I. The effects of common peroneal stimulation on the effort and speed of walking: a randomized controlled trial with chronic hemiplegic patients. Clin Rehabil 1997; 11: 201-210.
40. Barbeau H, Visintin M. Optimal outcomes obtained with bodyweight support combined with treadmill training in stroke subjects. Arch Phys Med Rehabil 2003; 84: 1458-1465.
41. Daly JJ, Hogan N, Perepezko EM, Krebs HI, Rogers JM, Goyal KS, et al. Response to upper-limb robotics and functional neuromuscular stimulation following stroke. J Rehabil Res Dev 2005; 42: 723-736.
42. Daly JJ, Roenigk K, Holcomb J, Rogers JM, Butler K, Gansen J, et al. A randomized controlled trial of functional neuromuscular stimulation in chronic stroke subjects. Stroke 2006; 37: 172-178.
43. Daly JJ, Sng K, Roenigk K, Fredrickson E, Dohring M. Intralimb coordination deficit in stroke survivors and response to treatment. Gait Posture 2007; 25: 412-418.
44. Hornby TG, Campbell DD, Kahn JH, Demott T, Moore JL, Roth HR. Enhanced gait-related improvements after therapistversus robotic-assisted locomotor training in subjects with chronic stroke: a randomized controlled study. Stroke 2008; 39: 1786-1792.
45. Sullivan K, Knowlton B, Dobkin B. Step training with body weight support: effect of treadmill speed and practice paradigms on poststroke locomotor recovery. Arch Phys Med Rehabil 2002; 83: 683-691.
46. Sullivan KJ, Brown DA, Klassen T, Mulroy S, Ge T, Azen SP, et al. Physical Therapy Clinical Research Network (PTClinResNet). Effects of task-specific locomotor and strength training in adults who were ambulatory after stroke: results of the STEPS randomized clinical trial. Phys Ther 2007; 87: 1580-1587.
47. Visintin M, Barbeau H, Korner-Bitensky N, Mayo NE. A new approach to retrain gait in stroke patients through body weight support and treadmill stimulation. Stroke 1998; 29: 1122-1128.
48. Werner C, von Frankenberg S, Treig T, Konrad M, Hesse S. Treadmill training with partial body weight support and an electromechanical gait trainer for restoration of gait in subacute stroke patients: a randomized crossover study. Stroke 2002a; 33: 2895-2901.
49. Werner C, Bardeleben A, Mauritz K, Kirker S, Hesse S. Treadmill training with partial body weight support and physiotherapy in stroke patients: a preliminary comparison. E J Neurol 2002b; 9: 639-644.
50. Yagura H, Hatakenaka M, Miyai I. Does therapeutic facilitation add to locomotor outcome of body weight-supported treadmill training in nonambulatory patients with stroke? a randomized controlled trial. Arch Phys Med Rehabil 2006; 87: 529-535.
51. Smith PS, Thompson M. Treadmill training post stroke: are there any secondary benefits? A pilot study. Clin Rehabil 2008; 22: 997-1002.
52. Langhammer B, Stanghelle JK, Lindmark B. An evaluation of two different exercise regimes during the first year following stroke: a randomised controlled trial. Physiother Theory Pract 2009; 25: 55-68.
53. Mulroy SJ, Winstein CJ, Kulig K, Beneck GJ, Fowler EG, De-Muth SK, et al. Secondary mediation and regression analyses of the PTClinResNet database: determining causal relationships among the International Classification of Functioning, Disability and Health levels for four physical therapy intervention trials. Physical Therapy Clinical Research Network. Phys Ther 2011; 91: 1766-1779.
54. Daly JJ, Zimbelman J, Roenigk KL, McCabe JP, Rogers JM, Butler K, et al. Recovery of coordinated gait: randomized controlled stroke trial of functional electrical stimulation (FES) versus no FES, with weight-supported treadmill and over-ground training. Neurorehab Neural Repair 2011; 25: 588-596.
55. Toledano-Zarhi A, Tanne D, Carmeli E, Katz-Leurer M. Feasibility, safety and efficacy of an early aerobic rehabilitation program for patients after minor ischemic stroke: a pilot randomized controlled trial. NeuroRehabilitation 2011; 28: 85-90.
56. Sungkarat S, Fisher BE, Kovindha A. Efficacy of an insole shoe wedge and augmented pressure sensor for gait training in individuals with stroke: a randomized controlled trial. Clin Rehab 2011; 25: 360-369.
57. Chouhan S, Kumar S, Walker S, Lloyd C. Comparative study of the effects of rhythmic auditory cueing and visual cueing in acute hemiparetic stroke. IJTRR 2012; 19: 1-8.
58. Ivey FM, Hafer-Macko CE, Ryan AS, Macko RF. Impaired leg vasodilatory function after stroke: adaptations with treadmill exercise training. Stroke 2010; 41: 2913-2917.
59. Yang YR, Chen IH, Liao KK, Huang CC, Wang RY. Cortical reorganization induced by body weight-supported treadmill training in patients with hemiparesis of different stroke durations. Arch Phys Med Rehabil 2010; 91: 513-518.
60. Ploughman M, McCarthy J, Bosse M, Sullivan HJ, Corbett D. Does treadmill exercise improve performance of cognitive or upper-extremity tasks in people with chronic stroke? A randomized cross-over trial. Arch Phys Med Rehabil 2008; 89: 2041-2047.
61. Tilson JK, Wu SS, Cen SY, Feng Q, Rose DR, Behrman AL, et al. Characterizing and identifying risk for falls in the LEAPS study: a randomized clinical trial of interventions to improve walking poststroke. Stroke 2012; 43: 446-452.
62. Shaughnessy M, Michael K, Resnick B. Impact of treadmill exercise on efficacy expectations, physical activity, and stroke recovery. J Neurosci Nurs 2012; 44: 27-35.
63. Ivey FM, Ryan AS, Hafer-Macko CE, Macko RF. Improved cerebral vasomotor reactivity after exercise training in hemiparetic stroke survivors. Stroke 2011; 42: 1994-2000.
64. Langhammer B, Stanghelle JK. Can physiotherapy after stroke based on the bobath concept result in improved quality of movement compared to the motor relearning programme. Physiother Res Int 2011; 16: 69-80.
65. Dean CM, Rissel C, Sharkey M, Sherrington C, Cumming RG, Barker RN, et al. Exercise intervention to prevent falls and enhance mobility in community dwellers after stroke: a protocol for a randomised controlled trial. BMC Neurol 2009; 9: 38.
66. Batchelor FA, Hill KD, Mackintosh SF, Said CM, Whitehead CH. The FLASSH study: protocol for a randomised controlled trial evaluating falls prevention after stroke and two sub-studies. BMC Neurol 2009; 9: 14.
67. Freivogel S, Schmalohr D, Mehrholz J. Improved walking ability and reduced therapeutic stress with an electromechanical gait device. J Rehabil Med 2009; 41: 734-739.
68. Kuys SS, Brauer SG, Ada L, Russell TG. Increasing intensity during treadmill walking does not adversely affect walking pattern or quality in newly-ambulating stroke patients: an experimental study. Aust J Physiother 2008; 54: 49-54.
69. Dal Farra F, Boem D, Magni S, Bernasconi L. Monticone M. Efficacy of the Regent Suit training during a post-acute stroke rehabilitation process: description of a case report. G Ital Med Lav Ergon 2011; 33: 74-83.
70. Tyrell CM, Roos MA, Rudolph KS, Reisman DS. Influence of systematic increases in treadmill walking speed on gait kinematics after stroke. Phys Ther 2011; 91: 392-403.
71. Dobkin BH, Plummer-D'Amato P, Elashoff R, Lee J, SIRROWS Group. International randomized clinical trial, stroke inpatient rehabilitation with reinforcement of walking speed (SIRROWS), improves outcomes. Neurorehabil Neural Repair 2010; 24: 235-242.
72. Lau KW, Mak MK. Speed-dependent treadmill training is effective to improve gait and balance performance in patients with sub-acute stroke. J Rehabil Med 2011; 43: 709-713.
73. Chu KS, Eng JJ, Dawson AS, Harris JE, Ozkaplan A, Gylfadóttir S. Water-based exercise for cardiovascular fitness in people with chronic stroke: a randomized controlled trial. Arch Phys Med Rehabil 2004; 85: 870-874.
74. Kang HK, Kim Y, Chung Y. Hwang S. Effects of treadmill training with optic flow on balance and gait in individuals following stroke: randomized controlled trials. Clin Rehabil 2012; 26: 246-255.
75. Luft AR, Macko RF, Forrester LW, Villagra F, Ivey F, Sorkin JD, et al. Treadmill exercise activates subcortical neural networks and improves walking after stroke: a randomized controlled trial. Stroke 2008; 39: 3341-3350.
76. Macko RF, Ivey FM, Forrester LW, Hanley D, Sorkin JD, Katzel LI, et al. Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trial. Stroke 2005; 36: 2206-2211.
77. Moore JL, Roth EJ, Killian C, Hornby TG. Locomotor training improves daily stepping activity and gait efficiency in individuals poststroke who have reached a "plateau" in recovery. Stroke 2010; 41: 129-135.
78. Salbach NM, Mayo NE, Robichaud-Ekstrand S, Hanley JA, Richards CL, Wood-Dauphinee S. The effect of a task-oriented walking intervention on improving balance self-efficacy poststroke: a randomized, controlled trial. J Am Geriatr Soc 2005; 53: 576-582.
79. Salbach NM, Mayo NE, Wood-Dauphinee S, Hanley JA, Richards CL, Cote R. A task-orientated intervention enhances walking distance and speed in the first year post stroke: a randomized controlled trial. Clin Rehabil 2004; 18: 509-519.
80. Yang YR, Wang RY, Chen YC, Kao MJ. Dual-task exercise improves walking ability in chronic stroke: a randomized controlled trial. Arch Phys Med Rehabil 2007; 88: 1236-1240.
81. Dias D, Laíns J, Pereira A, Nunes R, Caldas J, Amaral C, et al. Can we improve gait skills in chronic hemiplegics? A randomised control trial with gait trainer. Eura Medicophys 2007; 43: 499-504.
82. Duncan PW, Sullivan KJ, Behrman AL, Azen SP, Wu SS, Nadeau SE, et al. LEAPS Investigative Team. Body-weight-supported treadmill rehabilitation after stroke. N Engl J Med 2011; 364: 2026-2036.
83. Fisher S, Lucas L, Thrasher TA. Robot-assisted gait training for patients with hemiparesis due to stroke. Top Stroke Rehabil 2011; 18: 269-276.
84. Globas C, Becker C, Cerny J, Lam JM, Lindemann U, Forrester LW, et al. Chronic stroke survivors benefit from high-intensity aerobic treadmill exercise: a randomized control trial. Neurorehabil Neural Repair 2012; 26: 85-95.
85. Hoyer E, Jahnsen R, Stanghelle JK, Strand LI. Body weight supported treadmill training versus traditional training in patients dependent on walking assistance after stroke: a randomized controlled trial. Disabil Rehabil 2012; 34: 210-219.
86. Jonsdottir J, Cattaneo D, Recalcati M, Regola A, Rabuffetti M, Ferrarin M, et al. Task-oriented biofeedback to improve gait in individuals with chronic stroke: motor learning approach. Neurorehabil Neural Repair 2010; 24: 478-485.
87. Kuys SS, Brauer SG, Ada L. Higher-intensity treadmill walking during rehabilitation after stroke in feasible and not detrimental to walking pattern or quality: a pilot randomized trial. Clin Rehabil 2011; 25: 316-326.
88. Mayr A, Kofler M, Quirbach E, Matzak H, Fröhlich K, Saltuari L. Prospective, blinded, randomized crossover study of gait rehabilitation in stroke patients using the Lokomat gait orthosis. Neurorehabil Neural Repair 2007; 21: 307-314.
89. Park HJ, Oh DW, Kim SY, Choi JD. Effectiveness of communitybased ambulation training for walking function of post-stroke hemiparesis: a randomized controlled pilot trial. Clin Rehabil 2011; 25: 451-459.
90. Yang Y, Yen J, Wang R, Yen L, Lieu F. Gait outcomes after additional backward walking training in patients with stroke: a randomized controlled trial. Clin Rehabil 2005; 19: 264-273.
91. Yen CL, Wang RY, Liao KK, Huang CC, Yang YR. Gait traininginduced change in corticomotor excitability in patients with chronic stroke. Neurorehabil Neural Repair 2008; 22: 22-30.
92. Ada L, Dean CM, Morris ME, Simpson JM, Katrak P. Randomized trial of treadmill walking with body weight support to establish walking in subacute stroke: the MOBILISE trial. Stroke 2010; 41: 1237-1242.
93. da Cunha Filho IT, Lim P, Qureshy H, Henson H, Monga T, Protas E. A comparison of regular rehabilitation and regular rehabilitation with supported treadmill ambulation training for acute stroke patients. J Rehabil Res Dev 2001; 38: 245-255.
94. da Cunha IT, Lim PA, Qureshy H, Henson H, Monga T, Protas EJ. Gait outcomes after acute stroke rehabilitation with supported treadmill ambulation training: a randomized controlled pilot study. Arch Phys Med Rehabil 2002; 83: 1258-1265.
95. Dean CM, Ada L, Bampton J, Morris ME, Katrak PH, Potts S. Treadmill walking with body weight support in subacute non-ambulatory stroke improves walking capacity more than overground walking: a randomised trial. J Physiother 2010; 56: 97-103.
96. Eich H, Mach H, Werner C, Hesse S. Aerobic treadmill plus Bobath walking training improves walking in subacute stroke: a randomized controlled trial. Clin Rehabil 2004; 18: 640-651.
97. Hidler J, Nichols D, Pelliccio M, Brady K, Campbell DD, Kahn JH, et al. Multicenter randomized clinical trial evaluating the effectiveness of the Lokomat in subacute stroke. Neurorehabil Neural Repair 2009; 23: 5-13.
98. Husemann B, Muller F, Krewer C, Heller S, Koenig E. Effects of locomotion training with assistance of a robot-driven gait orthosis in hemiparetic patients after stroke: a randomized controlled pilot study. Stroke 2007; 38: 349-354.
99. Kosak M, Reding M. Comparison of partial body weightsupported treadmill gait training versus aggressive bracing assisted walking post stroke. Neurorehabil Neural Repair 2000; 14: 13-19.
100. Langhammer B, Stanghelle JK. Exercise on a treadmill or walking outdoors? A randomized controlled trial comparing effectiveness of two walking exercise programmes late after stroke. Clin Rehabil 2010; 24: 46-54.
101. Morone G, Bragoni M, Iosa M, De Angelis D, Venturiero V, Coiro P, et al. Who may benefit from robotic-assisted gait training? A randomized clinical trial in patients with subacute stroke. Neurorehabil Neural Repair 2011; 25: 636-644.
102. Morone G, Iosa M, Bragoni M, De Angelis D, Venturiero V, Coiro P, et al. Who may have durable benefit from robotic gait training? A 2-year follow-up randomized controlled trial in patients with subacute stroke. Stroke 2012; 43: 1140-1142.
103. Morris ME, Matyas TA, Bach TM, Goldie PA. Electrogoniometric feedback: its effect on genu recurvatum in stroke. Arch Phys Med Rehabil 1992; 73: 1147-1154.
104. Ng MF, Tong RK, Li LS. A pilot study of randomized clinical controlled trial of gait training in subacute stroke patients with partial body-weight support electromechanical gait trainer and functional electrical stimulation: six-month follow-up. Stroke 2008; 39: 154-160.
105. Nilsson L, Carlsson J, Danielsson A, Fugl-Meyer A, Hellström K, Kristensen L, et al. Walking training of patients with hemiparesis at an early stage after stroke: a comparison of walking training on a treadmill with body weight support and walking training on the ground. Clin Rehabil 2001; 15: 515-527.
106. Olawale OA, Jaja SI, Anigbogu CN, Appiah-Kubi KO, Jones-Okai D. Exercise training improves walking function in an African group of stroke survivors: a randomized controlled trial. Clin Rehabil 2011; 25: 442-450.
107. Peurala SH, Tarkka IM, Pitkänen K, Sivenius J. The effectiveness of body weight-supported gait training and floor walking in patients with chronic stroke. Arch Phys Med Rehabil 2005; 86: 1557-1564.
108. Peurala SH, Airaksinen O, Huuskonen P, Jäkälä P, Juhakoski M, Sandell K, et al. Effects of intensive therapy using gait trainer or floor walking exercises early after stroke. J Rehabil Med 2009; 41: 166-173.
109. Pohl M, Mehrholz J, Ritschel C, Ruckriem S. Speed-dependent treadmill training in ambulatory hemiparetic stroke patients: a randomized controlled trial. Stroke 2002; 33: 553-558.
110. Pohl M, Werner C, Holzgraefe M, Kroczek G, Mehrholz J, Wingendorf I, et al. Repetitive locomotor training and physiotherapy improve walking and basic activities of daily living after stroke: a single-blind, randomized multicentre trial (DEutsche GAngtrainerStudie, DEGAS). Clin Rehabil 2007; 21: 17-27.
111. Schwartz I, Sajin A, Fisher I, Neeb M, Shochina M, Katz-Leurer M, et al. The effectiveness of locomotor therapy using robotic-assisted gait training in subacute stroke patients: a randomized controlled trial. PM&R 2009; 1: 516-523.
112. Tong RK, Ng MF, Li LS. Effectiveness of gait training using an electromechanical gait trainer, with and without functional electric stimulation, in subacute stroke: a randomized controlled trial. Arch Phys Med Rehabil 2006; 87: 1298-1304.
113. Thaut MH, McIntosh GC, Rice RR. Rhythmic facilitation of gait training in hemiparetic stroke rehabilitation. J Neurol Sci 1997; 151: 207-212.
114. Thaut MH, Leins AK, Rice RR, Argstatter H, Kenyon GP, McIntosh GC, et al. Rhythmic auditory stimulation improves gait more than NDT/Bobath training in near-ambulatory patients early poststroke: a single-blind, randomized trial. Neurorehabil Neural Repair 2007; 21: 455-459.
115. Holden M, Gill K, Magliozzi M, Nathan J, Piehl-Baker L. Clinical gait assessment in the neurologically impaired. Reliability and meaningfulness. Phys Ther 1984; 64: 35-40.
116. Guyatt GH, Thompson PJ, Berman LB, Sullivan MJ, Townsend M, Jones NL, et al. How should we measure function in patients with chronic heart and lung disease? J Chronic Dis 1985; 38: 517-524.
117. Keith RA, Granger CV, Hamilton BB, Sherwin FS. The functional independence measure: a new tool for rehabilitation. Adv Clin Rehabil 1987; 1: 6-18.
118. Mahoney FI, Barthel DW. Functional evaluation: the Barthel Index. Md State Med J 1965; 14: 61-65.
119. Kwakkel G, Wagenaar RC, Twisk JW, Lankhorst GJ, Koetsier JC. Intensity of leg and arm training after primary middle-cerebral-artery stroke: a randomised trial. Lancet 1999; 354: 191-196.
120. Fulk GD, Echternach JL. Test-retest reliability and minimal detectable change of gait speed in individuals undergoing rehabilitation after stroke. J Neurol Phys Ther 2008; 32: 8-13.
121. Latham NK, Jette DU, Slavin M, Richards LG, Procino A, Smout RJ, et al. Physical therapy during stroke rehabilitation for people with different walking abilities. Arch Phys Med Rehabil 2005; 86: S41-S50.
122. Jette DU, Latham NK, Smout RJ, Gassaway J, Slavin MD, Horn SD. Physical therapy interventions for patients with stroke in inpatient rehabilitation facilities. Phys Ther 2005; 85: 238-248.
123. Stoller O, de Bruin ED, Knols RH, Hunt KJ. Effects of cardiovascular exercise early after stroke: systematic review and meta-analysis. BMC Neurol 2012; 12: 45.