Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy

Human Molecular Genetics

Volumn 23, Issue 14, 2014, Pages 3779-3791

  Beraldi, Rosanna ^a   Li, Xing ^a   Fernandez, Almudena Martinez ^a   Reyes, Santiago ^a   Secreto, Frank ^a   Terzic, Andre ^a   Olson, Timothy M ^a   Nelson, Timothy J ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CAMK 2 D PROTEIN; CONNECTIN; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTOME; UNCLASSIFIED DRUG; CALCIUM; RBM20 PROTEIN, MOUSE; RIBONUCLEIC ACID BINDING MOTIF PROTEIN 20, HUMAN; RNA BINDING PROTEIN;

ARTICLE; CALCIUM CELL LEVEL; CARDIOGENESIS; CELL DIFFERENTIATION; CELL POPULATION; CELL ULTRASTRUCTURE; CONGESTIVE CARDIOMYOPATHY; EXTRACELLULAR MATRIX; GENE; GENE DISRUPTION; GENE OVEREXPRESSION; GENE SILENCING; HEART MUSCLE BIOPSY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; PATHOGENESIS; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RBM20 GENE; RNA PROCESSING; SARCOMERE; ANIMAL; BIOLOGICAL MODEL; CARDIOMYOPATHY, DILATED; CELL LINE; EMBRYOID BODY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; HEART; METABOLISM; MOUSE; PATHOLOGY; RNA SPLICING; ULTRASTRUCTURE;

ANIMALS; CALCIUM; CARDIOMYOPATHY, DILATED; CELL DIFFERENTIATION; CELL LINE; EMBRYOID BODIES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HEART; HUMANS; MICE; MODELS, BIOLOGICAL; PLURIPOTENT STEM CELLS; RNA SPLICING; RNA-BINDING PROTEINS; SARCOMERES;

EID: 84902973424     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu091     Document Type: Article

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