A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice

Human Molecular Genetics

Volumn 23, Issue 14, 2014, Pages 3792-3880

  Shi, Fubiao ^a   Ding, Sheng ^a,d   Zhao, Shimin ^a   Han, Min ^a,b   Zhuang, Yuan ^a,c   Xu, Tian ^a,d   Wu, Xiaohui ^a  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY OF COLORADO   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXL2; UNCLASSIFIED DRUG; FOXL2 PROTEIN, MOUSE; TRANSPOSON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; AUTOSOMAL DOMINANT DISORDER; BPES SYNDROME; CELL CULTURE; CHROMOSOME CONFORMATION CAPTURE ASSAY; CONTROLLED STUDY; CRANIOFACIAL DEVELOPMENT; DNA FLANKING REGION; DNASE I HYPERSENSITIVITY ASSAY; EYE MALFORMATION; EYELID ABNORMALITY; FACE DEVELOPMENT; FEMALE; FEMALE SUBFERTILITY; GENE INSERTION; GROWTH RETARDATION; HOMOZYGOTE; IN VIVO STUDY; INCISOR; JAW; MANDIBLE; MAXILLA; MIDFACE HYPOPLASIA; MUTAGENESIS; MUTATION; NONHUMAN; PIGGYBAC INSERTION; PREMAXILLA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKULL; SKULL MALFORMATION; TISSUE CULTURE CELL; TRANSCRIPTION INITIATION SITE; ANIMAL; BLEPHAROPHIMOSIS; CONGENITAL SKIN DISEASE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MOUSE; PATHOLOGY; TRANSPOSON;

ANIMALS; BLEPHAROPHIMOSIS; DISEASE MODELS, ANIMAL; DNA TRANSPOSABLE ELEMENTS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MAXILLA; MICE; MUTAGENESIS, INSERTIONAL; SKIN ABNORMALITIES;

EID: 84902968796     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu092     Document Type: Article

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