Analysis of BRCA2 loss of heterozygosity in tumor tissue using droplet digital polymerase chain reaction

Human Pathology

Volumn 45, Issue 7, 2014, Pages 1546-1550

  Cochran, Rory L ^a   Cravero, Karen ^a   Chu, David ^a   Erlanger, Bracha ^a   Toro, Patricia Valda ^a   Beaver, Julia A ^a   Zabransky, Daniel J ^a   Wong, Hong Yuen ^a   Cidado, Justin ^a   Croessmann, Sarah ^a   Parsons, Heather A ^a   Kim, Minsoo ^a   Wheelan, Sarah J ^a   Argani, Pedram ^a   Park, Ben Ho ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

BRCA2; Droplet digital PCR; Familial breast cancer; LOH; VUS

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; ALLELE; AMPLICON; ARTICLE; BRCA2 GENE; BREAST CARCINOMA; CASE REPORT; CONTROLLED STUDY; DROPLET DIGITAL POLYMERASE CHAIN REACTION; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; EXON; FEMALE; GENE SEQUENCE; GENETIC SCREENING; GENETIC VARIABILITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; INTRADUCTAL CARCINOMA; MIDDLE AGED; MISSENSE MUTATION; ONCOGENE; POLYMERASE CHAIN REACTION; PROGESTERONE RECEPTOR POSITIVE CANCER; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SANGER SEQUENCING; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE; VARIANTS OF UNCLEAR CLINICAL SIGNIFICANCE;

BRCA2; DROPLET DIGITAL PCR; FAMILIAL BREAST CANCER; LOH; VUS;

ALLELES; BRCA2 PROTEIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; GENOTYPE; HUMANS; LOSS OF HETEROZYGOSITY; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION;

EID: 84902962491     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2014.03.013     Document Type: Article

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