Biased hypermutation occurred frequently in a gene inserted into the IC323 recombinant measles virus during its persistence in the brains of nude mice

Virology

Volumn 462-463, Issue 1, 2014, Pages 91-97

  Otani, Sanae ^a   Ayata, Minoru ^a   Takeuchi, Kaoru ^b   Takeda, Makoto ^c   Shintaku, Haruo ^a   Ogura, Hisashi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Adenosine deaminase acting on RNA; Measles; MIBE; Mutation; Persistent infection; SSPE

Indexed keywords

DIHYDROLIPOAMIDE DEHYDROGENASE; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; M PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENCEPHALITIS; FEMALE; GENE INSERTION; GFP GENE; H GENE; L GENE; M GENE; MEASLES INCLUSION BODY ENCEPHALITIS; MEASLES VIRUS; MOUSE; MUTATIONAL ANALYSIS; N GENE; NONHUMAN; PRIORITY JOURNAL; RENILLA RENIFORMIS; SUBACUTE SCLEROSING PANENCEPHALITIS; VIRUS GENE; VIRUS GENOME; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ADENOSINE DEAMINASE ACTING ON RNA; MEASLES; MIBE; MUTATION; PERSISTENT INFECTION; SSPE;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; ENCEPHALITIS, VIRAL; FEMALE; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; MEASLES; MEASLES VIRUS; MICE; MICE, NUDE; MUTANT PROTEINS; MUTATION;

EID: 84902959044     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2014.05.035     Document Type: Article

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