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Volumn 3, Issue , 2013, Pages

Defined lipid analogues induce transient channels to facilitate drug-membrane traversal and circumvent cancer therapy resistance

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; GLYCEROPHOSPHOLIPID; GLYCOSPHINGOLIPID; LIPOSOME;

EID: 84902941080     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep01949     Document Type: Article
Times cited : (24)

References (35)
  • 2
    • 0017125226 scopus 로고
    • Water and nonelectrolyte permeability of lipid bilayer membranes
    • Finkelstein, A.Water and nonelectrolyte permeability of lipid bilayer membranes. J. Gen. Physiol. 68, 127-135 (1976)
    • (1976) J. Gen. Physiol , vol.68 , pp. 127-135
    • Finkelstein, A.1
  • 3
    • 0040914512 scopus 로고    scopus 로고
    • One hundred years of membrane permeability: Does Overton still rule? Nat
    • Al-Awqati, Q. One hundred years of membrane permeability: does Overton still rule? Nat. Cell. Biol. 1, E201-202 (1999)
    • (1999) Cell. Biol , vol.1 , pp. E201-202
    • Al-Awqati, Q.1
  • 4
    • 40049110714 scopus 로고    scopus 로고
    • Carrier-mediated cellular uptake of pharmaceutical drugs: An exception or the rule? Nat
    • Dobson, P. D. &Kell, D. B. Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule? Nat. Rev. Drug. Discov. 7, 205-220 (2008)
    • (2008) Rev. Drug. Discov , vol.7 , pp. 205-220
    • Dobson, P.D.1    Kell, D.B.2
  • 5
    • 77955159974 scopus 로고    scopus 로고
    • Coexistence of passive and carrier-mediated processes in drug transport
    • Sugano, K. et al. Coexistence of passive and carrier-mediated processes in drug transport. Nat. Rev. Drug. Discov. 9, 597-614 (2010)
    • (2011) Nat. Rev. Drug. Discov , vol.9 , pp. 597-614
    • Sugano, K.1
  • 6
    • 0032781104 scopus 로고    scopus 로고
    • Doxorubicin Gradients in Human Breast Cancer
    • Lankelma, J. et al. Doxorubicin Gradients in Human Breast Cancer. Clin. Cancer Res. 5, 1703-1707 (1999)
    • (1999) Clin. Cancer Res , vol.5 , pp. 1703-1707
    • Lankelma, J.1
  • 7
    • 0030701599 scopus 로고    scopus 로고
    • Flip-flop of doxorubicin across erythrocyte and lipid membranes
    • Regev, R. &Eytan, G. D. Flip-flop of doxorubicin across erythrocyte and lipid membranes. Biochem. Pharmacol. 54, 1151-1158 (1997)
    • (1997) Biochem. Pharmacol , vol.54 , pp. 1151-1158
    • Regev, R.1    Eytan, G.D.2
  • 8
    • 0026352832 scopus 로고
    • Sterically stabilized liposomes: Improvements in pharmacokinetics and antitumor therapeutic efficacy
    • Papahadjopoulos, D. et al. Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc. Natl. Acad. Sci. USA 88, 11460-11464 (1991)
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11460-11464
    • Papahadjopoulos, D.1
  • 9
    • 11144357506 scopus 로고    scopus 로고
    • Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment ofmetastatic breast cancer
    • O'Brien, M. E. et al. Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment ofmetastatic breast cancer. Ann. Oncol. 15, 440-449 (2004)
    • (2004) Ann. Oncol , vol.15 , pp. 440-449
    • O'Brien, M.E.1
  • 10
    • 79251547946 scopus 로고    scopus 로고
    • Enriching lipid nanovesicles with short-chain glucosylceramide improves doxorubicin delivery and efficacy in solid tumors
    • van Lummel, M. et al. Enriching lipid nanovesicles with short-chain glucosylceramide improves doxorubicin delivery and efficacy in solid tumors. FASEB J. 25, 280-289 (2011)
    • (2011) FASEB J , vol.25 , pp. 280-289
    • Van Lummel, M.1
  • 11
    • 1642337349 scopus 로고    scopus 로고
    • N-hexanoylsphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx
    • Veldman, R. J., Zerp, S., van Blitterswijk, W. J. &Verheij, M. N-hexanoylsphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx. Br. J. Cancer 90, 917-925 (2004)
    • (2004) Br. J. Cancer , vol.90 , pp. 917-925
    • Veldman, R.J.1    Zerp, S.2    Van Blitterswijk, W.J.3    Verheij, M.4
  • 12
    • 33750406161 scopus 로고
    • Theory of self-Assembly of hydrocarbon amphiphiles into micelles and bilayers
    • Israelachvili, J. N., Mitchell, D. J. &Ninham, B. W. Theory of self-Assembly of hydrocarbon amphiphiles into micelles and bilayers. J. Chem. Soc., Faraday Trans. 2 72, 1525-1568 (1976)
    • (1976) J. Chem. Soc., Faraday Trans , vol.2 , Issue.72 , pp. 1525-1568
    • Israelachvili, J.N.1    Mitchell, D.J.2    Ninham, B.W.3
  • 13
    • 77955410527 scopus 로고    scopus 로고
    • Permeability of drugs and hormones through a lipid bilayer: Insights from dual-resolution molecular dynamics
    • Orsi, M. &Essex, J. W. Permeability of drugs and hormones through a lipid bilayer: insights from dual-resolution molecular dynamics. Soft Matter 6, 3797-3808 (2010)
    • (2011) Soft Matter , vol.6 , pp. 3797-3808
    • Orsi, M.1    Essex, J.W.2
  • 14
    • 0026067425 scopus 로고
    • Comparable interaction of doxorubicin with various acidic phospholipids results in changes of lipid order and dynamics
    • de Wolf, F. A. et al. Comparable interaction of doxorubicin with various acidic phospholipids results in changes of lipid order and dynamics. Biochim. Biophys. Acta 1096, 67-80 (1990)
    • (1990) Biochim. Biophys. Acta , vol.1096 , pp. 67-80
    • De Wolf, F.A.1
  • 15
    • 79956108858 scopus 로고    scopus 로고
    • Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice
    • Derksen, P. W. et al. Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice. Dis. Model. Mech. 4, 347-358 (2011)
    • (2011) Dis. Model. Mech , vol.4 , pp. 347-358
    • Derksen, P.W.1
  • 16
    • 33750614651 scopus 로고    scopus 로고
    • Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis
    • Derksen, P. W. et al. Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. Cancer Cell 10, 437-449 (2006)
    • (2006) Cancer Cell , vol.10 , pp. 437-449
    • Derksen, P.W.1
  • 17
    • 27144447790 scopus 로고    scopus 로고
    • Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin
    • Veldman, R. J. et al. Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin. J. Pharmacol. Exp. Ther. 315, 704-710 (2005)
    • (2005) J. Pharmacol. Exp. Ther , vol.315 , pp. 704-710
    • Veldman, R.J.1
  • 18
    • 0026612730 scopus 로고
    • Use of N-([1-14C]hexanoyl)-D-erythrosphingolipids to assay sphingolipid metabolism
    • Futerman, A. H. &Pagano, R. E. Use of N-([1-14C]hexanoyl)-D-erythrosphingolipids to assay sphingolipid metabolism. Methods Enzymol. 209, 437-446 (1992)
    • (1992) Methods Enzymol , vol.209 , pp. 437-446
    • Futerman, A.H.1    Pagano, R.E.2
  • 19
    • 80052483718 scopus 로고    scopus 로고
    • Chemotherapy use and risk of bone marrow suppression in a large population-based cohort of older women with breast and ovarian cancer
    • Nurgalieva, Z., Liu, C. C. &Du, X. L. Chemotherapy use and risk of bone marrow suppression in a large population-based cohort of older women with breast and ovarian cancer. Med. Oncol. (2010)
    • (2011) Med. Oncol
    • Nurgalieva, Z.1    Liu, C.C.2    Du, X.L.3
  • 20
    • 0024418366 scopus 로고
    • Anemia and cancer
    • Steinberg, D. Anemia and cancer. CA: Cancer J. Clin. 39, 296-304 (1989)
    • (1989) CA: Cancer J. Clin , vol.39 , pp. 296-304
    • Steinberg, D.1
  • 21
    • 20444427641 scopus 로고    scopus 로고
    • Measuring the doxorubicin content of single Nuclei by Micellar Electrokinetic Capillary Chromatography with Laser-Induced Fluorescence Detection
    • Xiong, G., Chen, Y. &Arriaga, E. A. Measuring the Doxorubicin Content of Single Nuclei by Micellar Electrokinetic Capillary Chromatography with Laser-Induced Fluorescence Detection. Anal. Chem. 77, 3488-3493 (2005)
    • (2005) Anal. Chem , vol.77 , pp. 3488-3493
    • Xiong, G.1    Chen, Y.2    Arriaga, E.A.3
  • 22
    • 0037681850 scopus 로고    scopus 로고
    • Pharmacokinetics of pegylated liposomal Doxorubicin: Review of animal and human studies
    • Gabizon, A., Shmeeda, H. &Barenholz, Y. Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies. Clin. Pharm. 42, 419-436 (2003)
    • (2003) Clin. Pharm , vol.42 , pp. 419-436
    • Gabizon, A.1    Shmeeda, H.2    Barenholz, Y.3
  • 23
    • 79953054576 scopus 로고    scopus 로고
    • The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • Fang, J., Nakamura, H. &Maeda, H. The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv. Drug Del. Rev. 63, 136-151 (2011)
    • (2011) Adv. Drug Del. Rev , vol.63 , pp. 136-151
    • Fang, J.1    Nakamura, H.2    Maeda, H.3
  • 24
    • 37249061592 scopus 로고    scopus 로고
    • What Makes Tumors Multidrug Resistant?
    • Borst, P., Jonkers, J. &Rottenberg, S. What Makes Tumors Multidrug Resistant? Cell Cycle 6, 2782-2787 (2007)
    • (2007) Cell Cycle , vol.6 , pp. 2782-2787
    • Borst, P.1    Jonkers, J.2    Rottenberg, S.3
  • 25
    • 20444389423 scopus 로고    scopus 로고
    • Transport of anthracyclines and mitoxantrone across membranes by a flip-flop mechanism
    • Regev, R., Yeheskely-Hayon, D., Katzir, H. &Eytan, G. D. Transport of anthracyclines and mitoxantrone across membranes by a flip-flop mechanism. Biochem. Pharmacol. 70, 161-169 (2005)
    • (2005) Biochem. Pharmacol , vol.70 , pp. 161-169
    • Regev, R.1    Yeheskely-Hayon, D.2    Katzir, H.3    Eytan, G.D.4
  • 26
    • 74849118341 scopus 로고    scopus 로고
    • Lipid rafts as a membrane-organizing principle
    • Lingwood, D. &Simons, K. Lipid rafts as a membrane-organizing principle. Science 327, 46-50 (2010)
    • (2011) Science , vol.327 , pp. 46-50
    • Lingwood, D.1    Simons, K.2
  • 27
    • 0024024676 scopus 로고
    • Fluorescence depolarization measurements on oriented membranes
    • Adler, M. &Tritton, T. R. Fluorescence depolarization measurements on oriented membranes. Biophys. J. 53, 989-1005 (1988)
    • (1988) Biophys. J , vol.53 , pp. 989-1005
    • Adler, M.1    Tritton, T.R.2
  • 28
    • 79959398473 scopus 로고    scopus 로고
    • Applications of Mass Spectrometry to Lipids and Membranes
    • Harkewicz, R. &Dennis, E. A. Applications of Mass Spectrometry to Lipids and Membranes. Ann. Rev. Biochem. 80, 301-325 (2011)
    • (2011) Ann. Rev. Biochem , vol.80 , pp. 301-325
    • Harkewicz, R.1    Dennis, E.A.2
  • 29
    • 0024192174 scopus 로고
    • Atherosclerosis endothelium and plasma membrane lipid polarity
    • van Meer, G. Atherosclerosis, endothelium and plasma membrane lipid polarity. Agents Actions Suppl. 26, 15-25 (1988)
    • (1988) Agents Actions Suppl , vol.26 , pp. 15-25
    • Van Meer, G.1
  • 30
    • 79952149347 scopus 로고    scopus 로고
    • Membrane lipidome of an epithelial cell line
    • Sampaio, J. L. et al.Membrane lipidome of an epithelial cell line. Proc. Natl. Acad. Sci. USA 108, 1903-1907 (2010)
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 1903-1907
    • Sampaio, J.L.1
  • 31
    • 79959398473 scopus 로고    scopus 로고
    • Applications of mass spectrometry to lipids and membranes
    • Harkewicz, R. &Dennis, E. A. Applications of mass spectrometry to lipids and membranes. Annu. Rev. Biochem. 80, 301-325 (2011)
    • (2011) Annu. Rev. Biochem , vol.80 , pp. 301-325
    • Harkewicz, R.1    Dennis, E.A.2
  • 32
    • 77954956306 scopus 로고    scopus 로고
    • Lipidomics: Coming to grips with lipid diversity
    • Shevchenko, A. &Simons, K. Lipidomics: coming to grips with lipid diversity. Nat Rev. Mol. Cell. Biol. 11, 593-598 (2010)
    • (2011) Nat Rev. Mol. Cell. Biol , vol.11 , pp. 593-598
    • Shevchenko, A.1    Simons, K.2
  • 33
    • 0036142158 scopus 로고    scopus 로고
    • Liposome-encapsulated doxorubicin compared with conventional doxorubicin in a randomized multicenter trial as first-line therapy of metastatic breast carcinoma
    • Harris, L. et al. Liposome-encapsulated doxorubicin compared with conventional doxorubicin in a randomized multicenter trial as first-line therapy of metastatic breast carcinoma. Cancer 94, 25-36 (2002)
    • (2002) Cancer , vol.94 , pp. 25-36
    • Harris, L.1
  • 34
    • 34547852276 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin-related palmar-plantar erythrodysesthesia ('hand-foot' syndrome
    • Lorusso, D. et al. Pegylated liposomal doxorubicin-related palmar-plantar erythrodysesthesia ('hand-foot' syndrome). Ann. Oncol. 18, 1159-1164 (2007)
    • (2007) Ann. Oncol , vol.18 , pp. 1159-1164
    • Lorusso, D.1
  • 35
    • 31844438479 scopus 로고    scopus 로고
    • ABC lipid transporters: Extruders, flippases, or flopless activators?
    • van Meer, G., Halter, D., Sprong, H., Somerharju, P. &Egmond, M. R. ABC lipid transporters: extruders, flippases, or flopless activators? FEBS Lett. 580, 1171-1177 (2006)
    • (2006) FEBS Lett , vol.580 , pp. 1171-1177
    • Van Meer, G.1    Halter, D.2    Sprong, H.3    Somerharju, P.4    Egmond, M.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.