Effect of transcutaneous auricular vagus nerve stimulation on impaired glucose tolerance: A pilot randomized study

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Huang, Feng ^a,b   Dong, Jianxun ^c   Kong, Jian ^d   Wang, Hongcai ^a   Meng, Hong ^a   Spaeth, Rosa B ^d   Camhi, Stephanie ^d,e   Liao, Xing ^a   Li, Xia ^b   Zhai, Xu ^a   Li, Shaoyuan ^a   Zhu, Bing ^a   Rong, Peijing ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c BEIJING HOSPITAL OF TRADITIONAL CHINESE MEDICINE AFFILIATED TO CAPITAL MEDICAL UNIVERSITY   (China)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e ENDICOTT COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOSYLATED HEMOGLOBIN;

ADULT; AGED; ARTICLE; COMPUTER; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DIET RESTRICTION; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; MAJOR CLINICAL STUDY; MALE; NERVE STIMULATOR; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SYSTOLIC BLOOD PRESSURE; THERAPY EFFECT; TRANSCUTANEOUS AURICULAR VAGUS NERVE STIMULATION; TRANSCUTANEOUS NERVE STIMULATION; TREATMENT DURATION; VAGUS NERVE; VAGUS NERVE STIMULATION;

ADULT; AGED; BLOOD GLUCOSE; FEMALE; GLUCOSE INTOLERANCE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; SINGLE-BLIND METHOD; VAGUS NERVE STIMULATION;

EID: 84902926685     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-203     Document Type: Article

References (18)

1. Tabak AG, Herder C, Rathmann W, Brunner EJ, Kivimaki M. Prediabetes: a high-risk state for diabetes development. Lancet 2012, 379:2279-2290.
2. Harris MI. Impaired glucose tolerance in the U.S. population. Diabetes Care 1989, 12:464-474.
3. Brown DC, Byrne CD, Clark PM, Cox BD, Day NE, Hales CN, Shackleton JR, Wang TW, Williams DR. Height and glucose tolerance in adult subjects. Diabetologia 1991, 34:531-533.
4. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002, 346:393-403.
5. Warram JH, Sigal RJ, Martin BC, Krolewski AS, Soeldner JS. Natural history of impaired glucose tolerance: follow-up at Joslin Clinic. Diabet Med 1996, 13:S40-S45.
6. Keen H, Jarrett RJ, McCartney P. The ten-year follow-up of the Bedford survey (1962-1972): glucose tolerance and diabetes. Diabetologia 1982, 22:73-78.
7. Group UKPDS: UK Prospective Diabetes Study (UKPDS). XI Biochemical risk factors in type 2 diabetic patients at diagnosis compared with age-matched normal subjects. Diabet Med 1994, 11:534-544. Group UKPDS: UK Prospective Diabetes Study (UKPDS). XI.
8. Moutzouri E, Tsimihodimos V, Rizos E, Elisaf M. Prediabetes: to treat or not to treat?. Eur J Pharmacol 2011, 672:9-19.
9. De Couck M, Mravec B, Gidron Y. You may need the vagus nerve to understand pathophysiology and to treat diseases. Clin Sci (Lond) 2012, 122:323-328.
10. Stefan H, Kreiselmeyer G, Kerling F, Kurzbuch K, Rauch C, Heers M, Kasper BS, Hammen T, Rzonsa M, Pauli E, Ellrich J, Graf W, Hopfengartner R. Transcutaneous vagus nerve stimulation (t-VNS) in pharmacoresistant epilepsies: a proof of concept trial. Epilepsia 2012, 53:e115-e118.
11. Hein E, Nowak M, Kiess O, Biermann T, Bayerlein K, Kornhuber J, Kraus T. Auricular transcutaneous electrical nerve stimulation in depressed patients: a randomized controlled pilot study. J Neural Transm 2013, 120:821-827.
12. Peuker ET, Filler TJ. The nerve supply of the human auricle. Clin Anat 2002, 15:35-37.
13. Rong PJ, Fang JL, Wang LP, Meng H, Liu J, Ma YG, Ben H, Li L, Liu RP, Huang ZX, Zhao YF, Li X, Zhu B, Kong J. Transcutaneous vagus nerve stimulation for the treatment of depression: a study protocol for a double blinded randomized clinical trial. BMC Complement Altern Med 2012, 12:255.
14. Organization WH Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia, Report of a WHO/IDF Consultation 2006, WHO Library Cataloguing-in-Publication Data, Organization WH.
15. Tarride JE, Lim M, DesMeules M, Luo W, Burke N, Oreilly D, Bowen J, Goeree R. A review of the cost of cardiovascular disease. Can J Cardiol 2009, 25:e195-e202.
16. Pavlov VA, Tracey KJ. The vagus nerve and the inflammatory reflex-linking immunity and metabolism. Nat Rev Endocrinol 2012, 8:743-754.
17. Koskinen T, Kahonen M, Jula A, Mattsson N, Laitinen T, Keltikangas-Jarvinen L, Viikari J, Valimaki I, Ronnemaa T, Raitakari OT. Metabolic syndrome and short-term heart rate variability in young adults. The cardiovascular risk in young Finns study. Diabet Med 2009, 26:354-361.
18. Licht CM, Vreeburg SA, Van Reedt Dortland AK, Giltay EJ, Hoogendijk WJ, DeRijk RH, Vogelzangs N, Zitman FG, De Geus EJ, Penninx BW. Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities. J Clin Endocrinol Metab 2010, 95:2458-2466.