Ultrafine fibrous gelatin scaffolds with deep cell infiltration mimicking 3D ECMs for soft tissue repair

Journal of Materials Science: Materials in Medicine

Volumn 25, Issue 7, 2014, Pages 1789-1800

  Jiang, Qiuran ^a   Xu, Helan ^a   Cai, Shaobo ^a   Yang, Yiqi ^a,b  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b University of Nebraska Lincoln   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; INFILTRATION; PHASE SEPARATION;

CELL INFILTRATION; CROSSLINKING SYSTEM; CURRENT TECHNOLOGY; CYTOCOMPATIBILITY; ELECTROSPUN SCAFFOLDS; EXTRACELLULAR MATRICES; FIBROUS SCAFFOLDS; FIBROUS STRUCTURES;

SCAFFOLDS (BIOLOGY);

CITRIC ACID; GELATIN; TISSUE SCAFFOLD; ULTRAFINE FIBROUS SCAFFOLD; UNCLASSIFIED DRUG; WATER; BIOMATERIAL; CROSS LINKING REAGENT;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; CELL INFILTRATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS LINKING; ELECTROSPINNING; EXTRACELLULAR MATRIX; MOLECULAR STABILITY; MOUSE; NONHUMAN; PARTICLE SIZE; PHASE SEPARATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOFT TISSUE; STROMA; 3T3 CELL LINE; ANIMAL; CELL DIFFERENTIATION; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; FIBROBLAST; MATERIALS TESTING; METABOLISM; PROCEDURES; STEM CELL; TIME; TISSUE ENGINEERING; TISSUE SCAFFOLD;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL DIFFERENTIATION; CELL SURVIVAL; CROSS-LINKING REAGENTS; EXTRACELLULAR MATRIX; FIBROBLASTS; GELATIN; MATERIALS TESTING; MICE; NIH 3T3 CELLS; STEM CELLS; TIME FACTORS; TISSUE ENGINEERING; TISSUE SCAFFOLDS; WATER;

EID: 84902858498     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-014-5208-2     Document Type: Article

References (35)

1. Dvir T, Timko BP, Kohane DS, Langer R. Nanotechnological strategies for engineering complex tissues. Nat Nanotechnol. 2011;6(1):13-22.
2. Sun T, Norton D, McKean RJ, Haycock JW, Ryan AJ, MacNeil S. Development of a 3D cell culture system for investigating cell interactions with electrospun fibers. Biotechnol Bioeng. 2007;97(5):1318-28. (Pubitemid 47195326)
3. Gavenis K, Schmidt-Rohlfing B, Mueller-Rath R, Andereya S, Schneider U. In vitro comparison of six different matrix systems for the cultivation of human chondrocytes. In Vitro Cell Dev Biol Anim. 2006;42(5-6):159-67. (Pubitemid 44744165)
4. 2. Biomaterials. 2009;30(1):1-7.
5. Wang HJ, Fu JX, Wang JY. Effect of water vapor on the surface characteristics and cell compatibility of zein films. Colloid Surf B. 2009;69(1):109-15.
6. Papenburg BJ, Bolhuis-Versteeg LAM, Grijpma DW, Feijen J, Wessling M, Stamatialis D. A facile method to fabricate poly (L-lactide) nano-fibrous morphologies by phase inversion. Acta Biomater. 2010;6(7):2477-83.
7. Wei GB, Ma PX. Nanostructured Biomaterials for Regeneration. Adv Funct Mater. 2008;18(22):3568-82.
8. Kim GM, Le KHT, Giannitelli SM, Lee YJ, Rainer A, Trombetta M. Electrospinning of PCL/PVP blends for tissue engineering scaffolds. J Mater Sci Mater Med. 2013;24(6):1425-42.
9. Fischer RL, McCoy MG, Grant SA. Electrospinning collagen and hyaluronic acid nanofiber meshes. J Mater Sci Mater Med. 2012;23(7):1645-54.
10. Tamayol A, Akbari M, Annabi N, Paul A, Khademhosseini A, Juncker D. Fiber-based tissue engineering: progress, challenges, and opportunities. Biotechnol Adv. 2013;31(5):669-87.
11. Bosworth LA, Alam N, Wong JK, Downes S. Investigation of 2D and 3D electrospun scaffolds intended for tendon repair. J Mater Sci Mater Med. 2013;24(6):1605-14.
12. Yokoyama Y, Hattori S, Yoshikawa C, Yasuda Y, Koyama H, Takato T, et al. Novel wet electrospinning system for fabrication of spongiform nanofiber 3-dimensional fabric. Mater Lett. 2009;63(9-10):754-6.
13. Moroni L, Schotel R, Hamann D, de Wijn JR, van Blitterswijk CA. 3D fiber-deposited electrospun integrated scaffolds enhance cartilage tissue formation. Adv Funct Mater. 2008;18(1):53-60. (Pubitemid 351143399)
14. Simonet M, Schneider OD, Neuenschwander P, Stark WJ. Ultraporous 3D polymer meshes by low-temperature electrospinning: use of ice crystals as a removable void template. Polym Eng Sci. 2007;47(12):2020-6.
15. Cai S, Xu H, Jiang Q, Yang Y. Novel 3D electrospun scaffolds with fibers oriented randomly and evenly in three dimensions to closely mimic the unique architectures of extracellular matrices in soft tissues: fabrication and mechanism study. Langmuir ACS J Surf Colloids. 2013;29(7):2311-8.
16. Brown JL, Peach MS, Nair LS, Kumbar SG, Laurencin CT. Composite scaffolds: bridging nanofiber and microsphere architectures to improve bioactivity of mechanically competent constructs. J Biomed Mater Res A. 2010;95(4):1150-8.
17. Liu XH, Ma PX. Phase separation, pore structure, and properties of nanofibrous gelatin scaffolds. Biomaterials. 2009;30(25):4094-103.
18. Wang J, Liu XH, Jin XB, Ma HY, Hu JA, Ni LX, et al. The odontogenic differentiation of human dental pulp stem cells on nanofibrous poly(L-lactic acid) scaffolds in vitro and in vivo. Acta Biomater. 2010;6(10):3856-63.
19. Nam YS, Park TG. Porous biodegradable polymeric scaffolds prepared by thermally induced phase separation. J Biomed Mater Res. 1999;47(1):8-17. (Pubitemid 29344964)
20. Liu XH, Smith L, Wei GB, Won YJ, Ma PX. Surface engineering of nano-fibrous poly(L-lactic acid) scaffolds via self-assembly technique for bone tissue engineering. J Biomed Nanotechnol. 2005;1(1):54-60.
21. Liu X, Smith LA, Hu J, Ma PX. Biomimetic nanofibrous gelatin/apatite composite scaffolds for bone tissue engineering. Biomaterials. 2009;30(12):2252-8.
22. Guan J, Fujimoto KL, Sacks MS, Wagner WR. Preparation and characterization of highly porous, biodegradable polyurethane scaffolds for soft tissue applications. Biomaterials. 2005;26(18):3961-71. (Pubitemid 40038787)
23. Cen L, Liu W, Cui L, Zhang WJ, Cao YL. Collagen tissue engineering: development of novel biomaterials and applications. Pediatr Res. 2008;63(5):492-6. (Pubitemid 351572218)
24. Barnes CP, Pemble CW, Brand DD, Simpson DG, Bowlin GL. Cross-linking electrospun type II collagen tissue engineering scaffolds with carbodiimide in ethanol. Tissue Eng. 2007;13(7):1593-605. (Pubitemid 47105766)
25. Sisson K, Zhang C, Farach-Carson MC, Chase DB, Rabolt JF. Evaluation of cross-linking methods for electrospun gelatin on cell growth and viability. Biomacromolecules. 2009;10(7):1675-80.
26. Saito Y, Nishio K, Yoshida Y, Niki E. Cytotoxic effect of formaldehyde with free radicals via increment of cellular reactive oxygen species. Toxicology. 2005;210(2-3):235-45. (Pubitemid 40520528)
27. Verma V, Verma P, Kar S, Ray P, Ray AR. Fabrication of agar-gelatin hybrid scaffolds using a novel entrapment method for in vitro tissue engineering applications. Biotechnol Bioeng. 2007;96(2):392-400. (Pubitemid 46232273)
28. Jiang Q, Reddy N, Zhang S, Roscioli N, Yang Y. Water-stable electrospun collagen fibers from a nontoxic solvent and crosslinking system. J Biomed Mater Res A. 2012;101:1237-47.
29. Yao C, Li XS, Song TY. Electrospinning and crosslinking of zein nanofiber mats. J Appl Polym Sci. 2007;103:380-5.
30. Jiang QR, Reddy N, Yang YQ. Cytocompatible cross-linking of electrospun zein fibers for the development of water-stable tissue engineering scaffolds. Acta Biomater. 2010;6(10):4042-51.
31. Gu SY, Wang ZM, Ren J, Zhang CY. Electrospinning of gelatin and gelatin/poly (L-lactide) blend and its characteristics for wound dressing. Mat Sci Eng C Mater. 2009;29(6):1822-8.
32. Jiang QR, Yang YQ. Water-stable electrospun zein fibers for potential drug delivery. J Biomater Sci Polym Ed. 2011;22(10):1393-408.
33. Hynes RO, Naba A. Overview of the matrisome - an inventory of extracellular matrix constituents and functions. Cold Spring Harb Perspect Biol. 2012;4(1):a004903.
34. Clark RK. Construction materials of your body: the tissue. In: Clark RK, editor. Anatomy and physiology: understanding the human body. America: Jones and Bartlett Publishers, Inc.; 2004. p. 65.
35. Hua FJ, Kim GE, Lee JD, Son YK, Lee DS. Macroporous poly(L-lactide) scaffold 1. Preparation of a macroporous scaffold by liquid-liquid phase separation of a PLLA-dioxane-water system. J Biomed Mater Res. 2002;63(2):161-7. (Pubitemid 34263860)