Symplocos cochinchinensis attenuates streptozotocin-diabetes induced pathophysiological alterations of liver, kidney, pancreas and eye lens in rats

Experimental and Toxicologic Pathology

Volumn 66, Issue 7, 2014, Pages 281-291

  Antu, Kalathookunnel Antony ^a   Riya, Mariam Philip ^a   Mishra, Arvind ^b   Sharma, Sharad ^b   Srivastava, Arvind K ^b   Raghu, Kozhiparambil Gopalan ^a  

^a REGIONAL RESEARCH LABORATORY CSIR   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

HbA1c; Aldose reductase; Aspartate aminotransferase; Carbonyl content; Creatinine; Diabetes; Insulin; Pancreas; Streptozotocin; Symplocos cochinchinensis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALCOHOL; ALDEHYDE REDUCTASE; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; CREATININE; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEMOGLOBIN A1C; MALONALDEHYDE; METFORMIN; PLANT EXTRACT; SUPEROXIDE DISMUTASE; SYMPLOCOS COCHINCHINENSIS EXTRACT; UNCLASSIFIED DRUG; UREA; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DOSE COMPARISON; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HISTOPATHOLOGY; HOMEOSTASIS; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; KIDNEY DISEASE; LENS DISEASE; LIVER DISEASE; LIVER LEVEL; MALE; MUSCLE LEVEL; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; OXIDATIVE STRESS; PANCREAS DISEASE; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; UPREGULATION; UREA BLOOD LEVEL; ANGIOSPERM; ANIMAL; BLOOD; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; ISOLATION AND PURIFICATION; KIDNEY; LENS; LIVER; MEDICINAL PLANT; PANCREAS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA; RATTUS; SYMPLOCOS COCHINCHINENSIS;

ANGIOSPERMS; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; KIDNEY; LENS, CRYSTALLINE; LIVER; MALE; OXIDATIVE STRESS; PANCREAS; PLANT BARK; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN;

EID: 84902832590     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2014.05.004     Document Type: Article

References (52)

1. Abbasi M.A. Bioactive chemical constituents of Symplocos recemosa and Comiphora mukul 2004, [Dissertation], University of Karachi, Pakistan.
2. American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care 2006, 29:43-48.
3. Anuradha C.V., Selvam R. Effect of oral methionine on tissue lipid peroxidation and antioxidants in alloxan induced diabetic rats. J Nutr Biochem 1993, 4:212-217.
4. Baynes J.W., Thorpe S.R. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 1999, 48:1-9.
5. Begum K., Rajini P.S. Augmentation of hepatic and renal oxidative stress and disrupted glucose homeostasis by monocrotophos in streptozotocin-induced diabetic rats. Chem Biol Inter 2011, 193:240-245.
6. Benecky M.J., Copeland R.A., Rava R.P., Feldhaus R., Scott R.D., Metzler C.M., et al. Resonance Raman spectra of the pyridoxal coenzyme in aspartate aminotransferase: evidence for pyridine protonation and a novel photochemical H/D exchange at the imine carbon atom. J Biol Chem 1985, 260:11671-11678.
7. Brownlee M. Biochemistry and molecular biology of diabetic complications. Nature 2011, 414:813-820.
8. Brownlee M. The pathology of diabetic complications: a unifying mechanism. Diabetes 2005, 54:1615-1625.
9. Calcutt N.A., Cooper M.E., Tim S., Kern T.S., Schmidt A.M. Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials. Nature Rev Drug Discov 2009, 8:417-429.
10. Chamundeswaramma K.V., Das P., Rathnamma V.V., Philip G.H. Activity levels of aspartate transaminase (AST) and alaninetransaminase (ALT) in freshwater fish Labeo rohita exposed to deltamethrin. Ecol Environ Conserv 2010, 16:145-148.
11. Chung S.S., Ho E.C., Lam K.S., Chung S.K. Contribution of polyol pathway to diabetes-induced oxidative stress. J Am Soc Nephrol 2003, 14:S233-S236.
12. DeFronzo R.A. Pathogenesis of type 2 diabetes mellitus. Med Clin N Am 2004, 88:787-835.
13. Dufrane D., van Steenberghe M., Guiot Y., Goebbels R.M., Saliez A., Gianello P. Streptozotocin-induced diabetes in large animals (pigs, primates): role of GLUT2 transporter and β-cell plasticity. Transplantation 2006, 81:36-45.
14. Efferth T., Koch E. Complex interactions between phytochemicals: the multi-target therapeutic concept of phytotherapy. Curr Drug Targets 2011, 12:122-132.
15. Feillet-Coudray C., Rock E., Coudray C., Grzelkowska K., Azais-Braesco V., Dardevet D., et al. Lipid peroxidation and antioxidant status in experimental diabetes. Clin Chim Acta 1999, 284:31-34.
16. Gabbay K.H. The sorbitol pathway and the complications of diabetes. N Engl J Med 1973, 288:831-836.
17. Gradinaru D., Borsa C., Ionescu C., Margina D. Advanced oxidative and glycoxidative protein damage markers in the elderly with type 2 diabetes. J Proteomics 2013, 92:313-322.
18. Graham M.L., Janecek J.L., Kittredge J.A., Hering B.J., Schuurman H.J. The streptozotocin-induced diabetic nude mouse model: differences between animals from different sources. Comp Med 2011, 61:356-360.
19. Hayman S., Kinoshita J.H. Isolation and properties of lens aldose reductase. J Biol Chem 1965, 240:877-882.
20. Hunt J.V., Smith C.C.T., Wolff S.P. Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 1990, 39:1420-1424.
21. Jones W.P., Kinghorn A.D. Extraction of plant secondary metabolites. Methods Mol Biol 2012, 864:341-366.
22. Mather K. Surrogate measures of insulin resistance: of rats, mice, and men. Am J Physiol Endocrinol Metab 2009, 296:E398-E399.
23. Kajimoto Y., Kaneto H. Role of oxidative stress in pancreatic beta-cell dysfunction. Ann N Y Acad Sci 2004, 1011:168-176.
24. Kashyap S.R., Defronzo R.A. The Insulin resistance syndrome: physiological considerations. Diab Vasc Dis Res 2007, 4:13-19.
25. Kim H.K., Kim M.J., Cho H.Y., Kim E.K., Shin D.H. Antioxidative and anti-diabetic effects of amaranth (Amaranthus esculantus) in streptozotocin induced diabetic rats. Cell Biochem Funct 2006, 24:195-199.
26. King G.L., Loeken M.R. Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 2004, 122:333-338.
27. Knox W.E., Greengard O. The regulation of some enzymes of nitrogen metabolism - an introduction to enzyme physiology. Adr Eniz Requlation 1965, 3:247-251.
28. Sahasrayogam-sujanapriya commentary 2000, 93. Vidyarambham Publishers, Alappuzha. K.V. Krishnanvaidyan, S.G. Pillai (Eds.).
29. Levinthal G.N., Tavill A.S. Liver disease and diabetes mellitus. Clin Diabetes 1999, 17(2). [accessed 08.04.14].
30. Lin Y., Sun Z. Current views on type 2 diabetes. J Endocrinol 2010, 204:1-11.
31. McLeod B.K., Thompson J.R., Rosenthal A.R. The prevalence of retinopathy in the insulin-requiring diabetic patients of an English country town. Eye 1988, 2:424-430.
32. Munro T.R. The relative radiosensitivity of the nucleus and cytoplasm of Chinese hamster fibroblasts. Radiat Res 1970, 42:451-470.
33. Nakakimura H., Mizuno K. Studies on lipid peroxidation in biological systems. II. Hyperlipoperoxidemia in mice induced by alloxan. Chem Pharmacol Bull 1980, 28:2207-2213.
34. Negi A., Vernon S.A. An overview of the eye in diabetes. J R Soc Med 2003, 96:266-272.
35. Nourooz-Zadeh J., Rahimi A., Tajaddini-Sarmadi J., Tritschler H., Rosen P., Halliwell B., et al. Relationships between plasma measures of oxidative stress and metabolic control in NIDDM. Diabetologia 1997, 40:647-653.
36. O'Brien T., Nguyen T., Zimmerman B.R. Hyperlipidemia and diabetes mellitus. Mayo Clin Proc 1998, 73:969-976.
37. Parveen K., Khan M.R., Mujeeb M., Siddiqui W.A. Protective effects of pycnogenol on hyperglycemia-induced oxidative damage in the liver of type 2 diabetic rats. Chem Biol Inter 2010, 186:219-227.
38. Rodriguez-Fontal M., Kerrison J.B., Alfaro D.V., Jablon E.P. Metabolic control and diabetic retinopathy. Curr Diabetes Rev 2009, 5:3-7.
39. Rubio-Tapia A., Murray J.A. The liver in celiac disease. Hepatology 2007, 46:1650-1658.
40. Singh A.B., Yadav D.K., Maurya R., Srivastava A.K. Antihyperglycaemic activity of alpha-amyrin acetate in rats and db/db mice. Nat Prod Res 2009, 23:876-882.
41. Srinivasan K., Ramarao P. Animal models in type 2 diabetes research: an overview. Indian J Med Res 2007, 125:451-472.
42. Subramanian V., Leelavinothan P. Antioxidant effect of Phaselous vulgaris in streptozotocin-induced diabetic rats. Asia Pacif J Clin Nutr 2002, 11:206-209.
43. Sunil C., Agastian P., Kumarappan C., Ignacimuthu S. In vitro antioxidant, antidiabetic and antilipidemic activities of Symplocos cochinchinensis (Lour.) S. Moore bark. Food Chem Toxicol 2012, 50:1547-1553.
44. Sunil C., Ignacimuthu S., Agastian P. Antidiabetic effect of Symplocos cochinchinensis (Lour.) S. Moore. in type 2 diabetic rats. J Ethnopharmacol 2011, 134:298-304.
45. Tatsuki R., Satoh H., Yamamoto A., Hoshi K., Ichihara K. Lipid peroxidation in the pancreas and other organs in streptozotocin diabetic rats. Jpn J Pharmacol 1997, 75:267-273.
46. Trease G.E., Evans W.C. Pharmacognosy I 1989, WB Saunders Co. Ltd., London. 12th ed.
47. UKPDS UK prospective diabetes study 33: intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications with type 2 diabetes. Lancet 1998, 352:837-853.
48. Viollet B., Guigas B., Sanz Garcia N., Leclerc J., Foretz M., Andreelli F. Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond) 2012, 122:253-270.
49. Whitton P.D., Hems D.A. Glycogen synthesis in the perfused liver of streptozotocin diabetic rats. Biochem J 1975, 150:153-165.
50. Wohaieb S.A., Godin D.V. Alterations in free radical tissue defense mechanisms in streptozotocin-induced diabetes in rat: effects of insulin treatment. Diabetes 1987, 36:1014-1018.
51. Wolff S.P., Dean R.T. Glucose autoxidation and protein modification: the potential role of 'autoxidative glycosylation' in diabetes. Biochem J 1987, 245:243-250.
52. Xu Y., He Z., King G.L. Introduction of hyperglycemia and dyslipidemia in the pathogenesis of diabetic vascular complications. Curr Diab Rep 2005, 5:91-97.