Diminished hERG K+ channel activity facilitates strong human labour contractions but is dysregulated in obese women

Nature Communications

Volumn 5, Issue , 2014, Pages

  Parkington, Helena C ^a   Stevenson, Janet ^b   Tonta, Mary A ^a   Paul, Jonathan ^c   Butler, Trent ^c   Maiti, Kaushik ^c   Chan, Eng Cheng ^c   Sheehan, Penelope M ^b   Brennecke, Shaun P ^b,d   Coleman, Harold A ^a   Smith, Roger ^c  

^a MONASH UNIVERSITY   (Australia)

^b ROYAL WOMEN'S HOSPITAL   (Australia)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL HERG ALPHA SUBUNIT; POTASSIUM CHANNEL HERG BETA SUBUNIT; UNCLASSIFIED DRUG; KCNE2 PROTEIN, HUMAN; KCNH1 PROTEIN, HUMAN; VOLTAGE GATED POTASSIUM CHANNEL;

CATION; GENE EXPRESSION; OBESITY; PHYSIOLOGY; POTASSIUM; PREGNANCY; PROTEIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LABOR; MATERNAL OBESITY; MUSCLE ACTION POTENTIAL; PATCH CLAMP TECHNIQUE; POTASSIUM CURRENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; UTERUS CONTRACTION; ACTION POTENTIAL; ADULT; BODY MASS; MEMBRANE POTENTIAL; METABOLISM; MYOMETRIUM; NONPARAMETRIC TEST; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

ACTION POTENTIALS; ADULT; BLOTTING, WESTERN; BODY MASS INDEX; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; HUMANS; MEMBRANE POTENTIALS; MYOMETRIUM; OBESITY; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, VOLTAGE-GATED; STATISTICS, NONPARAMETRIC; UTERINE CONTRACTION;

EID: 84902804765     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5108     Document Type: Article

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