Multi-wavelength photoacoustic imaging of inducible tyrosinase reporter gene expression in xenograft tumors

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Paproski, Robert J ^a   Heinmiller, Andrew ^b   Wachowicz, Keith ^a   Zemp, Roger J ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b Sonics Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DOXYCYCLINE; MELANIN; MONOPHENOL MONOOXYGENASE;

ANIMAL; BREAST NEOPLASMS; DIAGNOSTIC IMAGING; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HUMAN; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF 7 CELL LINE; METABOLISM; PHOTOACOUSTICS; PROCEDURES; REPORTER GENE; REPRODUCIBILITY; SCID MOUSE; SPECTROSCOPY; TUMOR CELL LINE;

ANIMALS; ANTI-BACTERIAL AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; DIAGNOSTIC IMAGING; DOXYCYCLINE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HEK293 CELLS; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF-7 CELLS; MELANINS; MICE, SCID; MONOPHENOL MONOOXYGENASE; PHOTOACOUSTIC TECHNIQUES; REPRODUCIBILITY OF RESULTS; SPECTRUM ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84902804583     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep05329     Document Type: Article

References (29)

1. Youn, H. & Chung, J. K. Reporter gene imaging. AJR Am. J. Roentgenol. 201, W206-214 (2013).
2. Min, J. J. & Gambhir, S. S. Molecular imaging of PET reporter gene expression. Handb. Exp. Pharmacol. 185, 277-303 (2008).
3. Zhang, J., Campbell, R. E., Ting, A. Y. & Tsien, R. Y. Creating new fluorescent probes for cell biology. Nat. Rev. Mol. Cell Biol. 3, 906-918 (2002). (Pubitemid 35477369)
4. de Almeida, P. E., van Rappard, J. R. & Wu, J. C. In vivo bioluminescence for tracking cell fate and function. Am. J. Physiol. Heart Circ. Physiol. 301, H663-671 (2011).
5. Gilad, A. A. et al. MRI reporter genes. J. Nucl. Med. 49, 1905-1908 (2008).
6. Li, L., Zemp, R. J., Lungu, G., Stoica, G. &Wang, L. V. Photoacoustic imaging of lacZ gene expression in vivo. J. Biomed. Opt. 12, 020504 (2007).
7. Paproski, R. J., Forbrich, A. E., Wachowicz, K., Hitt, M. M. & Zemp, R. J. Tyrosinase as a dual reporter gene for both photoacoustic and magnetic resonance imaging. Biomed. Opt. Express 2, 771-780 (2011).
8. Li, C. &Wang, L. V. Photoacoustic tomography and sensing in biomedicine. Phys. Med. Biol. 54, R59-97 (2009).
9. Wang, L. V. & Hu, S. Photoacoustic tomography: in vivo imaging from organelles to organs. Science 335, 1458-1462 (2012).
10. Li, L., Zhang, H. F., Zemp, R. J., Maslov, K. &Wang, L. Simultaneous imaging of a lacZ-marked tumor and microvasculature morphology in vivo by dualwavelength photoacoustic microscopy. J. Innov. Opt. Health Sci. 1, 207-215 (2008).
11. Zemp, R. J., Li, L. & Wang, L. V. [Photoacoustic imaging of gene expression in small animals in vivo]. Photoacoustic imaging and spectroscopy. (CRC Press, Boca Raton, 2009).
12. Filonov, G. S. et al. Deep-tissue photoacoustic tomography of a genetically encoded near-infrared fluorescent probe. Angew. Chem. Int. Ed. Engl. 51, 1448-1451 (2012).
13. Laufer, J., Jathoul, A., Pule, M. & Beard, P. In vitro characterization of genetically expressed absorbing proteins using photoacoustic spectroscopy. Biomed. Opt. Express 4, 2477-2490 (2013).
14. Liu, M. et al. In vivo three dimensional dual wavelength photoacoustic tomography imaging of the far red fluorescent protein E2-Crimson expressed in adult zebrafish. Biomed. Opt. Express 4, 1846-1855 (2013).
15. Razansky, D. et al. Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo. Nat. Photonics 3, 412-417 (2009).
16. Oetting, W. S. The tyrosinase gene and oculocutaneous albinism type 1 (OCA1):A model for understanding the molecular biology of melanin formation. Pigment Cell. Res. 13, 320-325 (2000).
17. Zonios, G. et al. Melanin absorption spectroscopy: new method for noninvasive skin investigation and melanoma detection. J. Biomed. Opt. 13, 014017 (2008).
18. Krumholz, A. et al. Photoacoustic microscopy of tyrosinase reporter gene in vivo. J. Biomed. Opt. 16, 080503 (2011).
19. Laufer, Y. et al. In vivo photoacoustic imaging of tyrosinase expressing tumours in mice. Proc. of SPIE, Phot. Plus Ultras. Imag. and Sens. 8223, 82230M-82231 (2012).
20. Qin, C. et al. Tyrosinase as a multifunctional reporter gene for Photoacoustic/MRI/PET triple modality molecular imaging. Sci. Rep. 3, 1490 (2013).
21. Stritzker, J. et al. Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer. Proc. Natl. Acad. Sci. USA 110, 3316-3320 (2013).
22. Sze, D. Y., Reid, T. R. & Rose, S. C. Oncolytic virotherapy. J. Vasc. Interv. Radiol. 24, 1115-1122 (2013).
23. Jordan-Sciutto, K. L., Wang, G., Murphey-Corb, M. & Wiley, C. A. Cell cycle proteins exhibit altered expression patterns in lentiviral-associated encephalitis. J. Neurosci. 22, 2185-2195 (2002). (Pubitemid 35386518)
24. Motavaf, M., Safari, S., Saffari Jourshari, M. & Alavian, S. M. Hepatitis B virusinduced hepatocellular carcinoma: the role of the virus x protein. Acta Virol. 57, 389-396 (2013).
25. Bertram, R. & Hillen, W. The application of Tet repressor in prokaryotic gene regulation and expression. Microb. Biotechnol. 1, 2-16 (2008).
26. Lee, Y. B., Glover, C. P., Cosgrave, A. S., Bienemann, A. & Uney, J. B. Optimizing regulatable gene expression using adenoviral vectors. Exp. Physiol. 90, 33-37 (2005).
27. Sun, Y., Chen, X. & Xiao, D. Tetracycline-inducible expression systems: new strategies and practices in the transgenic mouse modeling. Acta Biochim. Biophys. Sin. (Shanghai) 39, 235-246 (2007). (Pubitemid 46625305)
28. Alfke, H. et al. In vitro MR imaging of regulated gene expression. Radiology 228, 488-492 (2003). (Pubitemid 36910092)
29. Ponce, A. M. et al.Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects. J. Natl. Cancer Inst. 99, 53-63 (2007).