Mice exposed to diagnostic ultrasound in utero are less social and more active in social situations relative to controls

Autism Research

Volumn 7, Issue 3, 2014, Pages 295-304

  Mcclintic, Abbi M ^a   King, Bryan H ^a,b   Webb, Sara J ^a   Mourad, Pierre D ^a,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE CHILDREN S HOSPITAL   (United States)

^c University of Washington   (United States)

Author keywords

Autistic like behavior; Diagnostic ultrasound; Mouse social behavior; Risk factor

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; AUTISM; CONTROLLED STUDY; CORRELATIONAL STUDY; FEMALE; FETUS ECHOGRAPHY; MALE; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROGENY; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIAL INTERACTION TEST; ADVERSE EFFECTS; ANIMAL; ANIMAL BEHAVIOR; HUMAN; PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE; RISK FACTOR;

ANIMALS; BEHAVIOR, ANIMAL; FEMALE; HUMANS; MALE; MICE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RISK FACTORS; SOCIAL BEHAVIOR; ULTRASONOGRAPHY, PRENATAL;

EID: 84902780748     PISSN: 19393792     EISSN: 19393806     Source Type: Journal    
DOI: 10.1002/aur.1349     Document Type: Article

References (41)

1. Abramowicz, J.S. (2007). Prenatal exposure to ultrasound waves: Is there a risk? Ultrasound in Obstetrics and Gynecology, 29, 363-367.
2. Abramowicz, J.S. (2012). Ultrasound and autism: Association, link, or coincidence? Journal of Ultrasound in Medicine, 31, 1261-1269.
3. Ang, E.S. Jr., Gluncic, V., Duque, A., Schafer, M.E., & Rakic, P. (2006). Prenatal exposure to ultrasound waves impacts neuronal migration in mice. Proceedings of the National Academy of Sciences of the United States of America, 103, 12903-12910.
4. Autism and Developmental Disabilities Monitoring Network Surveillance Year 2008 Principal Investigators, Centers for Disease Control and Prevention (2012). Prevalence of autism spectrum disorders-Autism and developmental disabilities monitoring network, 14 sites, United States, 2008. MMWR Surveillance Summaries, 61, 1-19.
5. Center for Devices and Radiological Health (1997) Information for manufacturers seeking marketing clearance of diagnostic ultrasound systems and transducers (Food and Drug Administration, Rockville, MD).
6. Crawley, J.N. (2004). Designing Mouse Behavioral Tasks Relevant to Autistic-Like Behaviors. Mental Retardation and Developmental Disabilities Research Reviews, 10, 248-258.
7. Dane, S., & Balci, N. (2007). Handedness, eyedness and nasal cycle in children with autism. International Journal of Developmental Neuroscience, 25, 223-226.
8. Devi, P.U., Suresh, R., & Hande, M.P. (1995). Effect of fetal exposure to ultrasound on the behavior of the adult mouse. Radiation Research, 141, 314-317.
9. Fatemi, M., Ogburn, P.L. Jr., & Greenleaf, J.F. (2001). Fetal stimulation by pulsed diagnostic ultrasound. Journal of Ultrasound in Medicine, 20, 883-889.
10. FDA. (2013) "Avoid fetal 'keepsake' images, heartbeat monitors". Retrieved May 30, 2013, from http://www.fda.gov/forconsumers/consumerupdates/ucm095508.htm
11. Gibbs, V., Cole, D., & Sassano, A. (2009). Ultrasound physics and technology: How, why, and when (pp. 94-95). London, UK: Elsevier Health Sciences.
12. Grether, J.K., Li, S.X., Yoshida, C.K., & Croen, L.A. (2010). Antenatal ultrasound and risk of autism spectrum disorders. Journal of Autism and Developmental Disorders, 40, 238-245.
13. Hinoue, A., Fushiki, S., Nishimura, Y., Shiota, K. (2001). In utero exposure to brief hyperthermia interferes with the production and migration of neocortical neurons and induces apoptotic neuronal death in the fetal mouse brain. Developmental Brain Research, 132, 59-67.
14. Interagency Autism Coordinating Committee (IACC). (2012). IACC strategic plan for Autism Spectrum Disorder (ASD) research-2012 Update. Retrieved June 20, 2013, from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: http://iacc.hhs.gov/strategic-plan/2012/index.shtml
15. Jensh, R.P., Lewin, P.A., Poczobutt, M.T., Goldberg, B.B., Oler, J., etal. (1995). Effects of prenatal ultrasound exposure on adult offspring behavior in the wistar rat. Proceedings of the Society for Experimental Biology and Medicine, 210, 171-179.
16. Kalil, K., Li, L., & Hutchins, B.I. (2011). Signaling mechanisms in cortical axon growth, guidance, and branching. Front Neuroanat, 5, Article 62, 1-15.
17. Kaufman, M.H., & Bard, J.B.L. (1999). The anatomical basis of mouse development (pp. 171-193). San Diego, CA: Academic Press.
18. Krakowiak, P., Walker, C.K., Bremer, A.A., Baker, A.S., Ozonoff, S., etal. (2012). Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics, 129, e1121-e1128.
19. Lampi, K.M., Hinkka-Yli-Salomäki, S., Lehti, V., Helenius, H., Gissler, M., etal. (2013). Parental age and risk of autism spectrum disorders in a Finnish national birth cohort. Journal of Autism and Developmental Disorders, 43, 2526-2535.
20. Lyall, K., Pauls, D.L., Spiegelman, D., Ascherio, A., & Santangelo, S.L. (2012). Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the Nurses' Health Study II. Autism Research, 5, 21-30.
21. Matson, J.L., Rieske, R.D., & Williams, L.W. (2013). The relationship between autism spectrum disorders and attention-deficit/hyperactivity disorder: An overview. Research in Developmental Disabilities, 34, 2475-2484.
22. Mourad, P.D. (2012). Therapeutic ultrasound, with an emphasis on applications to the brain. In: Nakamura K. and Ueha S., (Eds.), Ultrasonic Transducers - Materials, Design, and Applications (pp. 454-571). Cambridge, UK: Woodhead.
23. Moy, S.S., Nadler, J.J., Young, N.B., Perez, A., Holloway, L.P., etal. (2007). Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains. Behavioral Brain Research, 176, 4-20.
24. Rados, C. (2004). FDA cautions against ultrasound "keepsake" images. FDA Consumer Magazine, 38, 12-16.
25. Salvesen, K.A. (2002). Epidemiology of diagnostic ultrasound exposure during pregnancy-European committee for medical ultrasound safety (ECMUS). European Journal of Ultrasound, 15, 165-171.
26. Salvesen, K.A. (2007) Epidemiological prenatal ultrasound studies. Progress in Biophysics and Molecular Biology, 93, 295-300.
27. Sandin, S., Hultman, C.M., Kolevzon, A., Gross, R., MacCabe, J.H., & Reichenberg, A. (2012). Advancing maternal age is associated with increasing risk for autism: A review and meta-analysis. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 477-486, e1.
28. Soper, H.V., Satz, P., Orsini, D.L., Henry, R.R., Zvi, J.C., & Schulman, M. (1986). Handedness patterns in autism suggest subtypes. Journal of Autism and Developmental Disorders, 16, 155-167.
29. Stalberg, K., Axelsson, O., Haglund, B., Hultman, C.M., Lambe, M., & Kieler, H. (2009). Prenatal ultrasound exposure and children's school performance at age 15-16: Follow-up of a randomized controlled trial. Ultrasound in Obstetrics and Gynecology, 34, 297-303.
30. Stewart, H.D., Stewart, H.F., Moore, R.M., & Garry, J. (1985). Compilation of reported biological effects data and ultrasound exposure levels. Journal of Clinical Ultrasound, 13, 167-186.
31. Stoch, Y.K., William, C.J., Granich, J., Hunt, A.M., Landau, L.I., etal. (2012). Are Prenatal ultrasound scans associated with the autism phenotype? Follow-up of a randomised controlled trial. Journal of Autism and Developmental Disorders, 42, 2693-2701.
32. Suresh, R., Devi, P.U., Ovchinnikov, N., & McRae, A. (2002). Long-term effects of diagnostic ultrasound during fetal period on postnatal development and adult behavior of mouse. Life Sciences, 71, 339-350.
33. Suresh, R., Rao, T.R., Davis, E.M., Ovchinnikov, N., & McRae, A. (2008). Effect of diagnostic ultrasound during the fetal period on learning and memory in mice. Annals of Anatomy, 190, 37-45.
34. ter Haar, G., Abramowicz, J.S., Akiyama, I., Evans, D.H., Ziskin, M.C., & Marsal, K. (2013). Do we need to restrict the use of Doppler ultrasound in the first trimester of Pregnancy? Ultrasound in Medicine and Biology, 39, 374-380.
35. Tufail, Y., Matyushov, A., Baldwin, N., Tauchmann, M.L., Georges, J., etal. (2010). Transcranial pulsed ultrasound stimulates intact brain circuits. Neuron, 66, 681-694.
36. Vorhees, C.V. (1986). Principles of behavioral teratology. In R.P. Riley & C.V. Vorhees (Eds.), Handbook of behavioral teratology (pp. 23-48). New York, NY: Plenum Press.
37. Whitworth, M., Bricker, L., Neilson, J.P., & Dowswell, T. (2010). Ultrasound for fetal assessment in early pregnancy. Cochrane Database of Systematic Reviews, 4, 1-68.
38. Williams, E.L., & Casanova, M.F. (2010). Potential teratogenic effects of ultrasound on corticogenesis: Implications for autism. Medical Hypotheses, 75, 53-58.
39. Williams, E.L., & Casanova, M.F. (2013). Reassessment of teratogenic risk from antenatal ultrasound. Translational Neuroscience, 4, 81-87.
40. Yang, M., Clarke, A.M., & Crawley, J.N. (2009). Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability. Behavioral Neuroscience, 29, 1663-1677.
41. Yang, M., Silverman, J.L., & Crawley, J.N. (2011). Automated Three-Chambered Social Approach Task for Mice. Current Protocols in Neuroscience, suppl. 56, 8.26.1-8.26.16.