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A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1
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[PMID: 23439262 DOI: 10.1016/j.jhep.2013.02.009]
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Lawitz E, Poordad F, Kowdley KV, Cohen DE, Podsadecki T, Siggelkow S, Larsen L, Menon R, Koev G, Tripathi R, Pilot-Matias T, Bernstein B. A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1. J Hepatol 2013; 59: 18-23 [PMID: 23439262 DOI: 10.1016/j.jhep.2013.02.009]
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(2013)
J Hepatol
, vol.59
, pp. 18-23
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Lawitz, E.1
Poordad, F.2
Kowdley, K.V.3
Cohen, D.E.4
Podsadecki, T.5
Siggelkow, S.6
Larsen, L.7
Menon, R.8
Koev, G.9
Tripathi, R.10
Pilot-Matias, T.11
Bernstein, B.12
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30
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84890977667
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Interim analysis of an interferon (IFN)-and ribavirin (RBV)-free regimen of daclatasvir (DCV), asunaprevir (ASV), and BMS-791325 in treatment-naive, hepatitis C virus genotype 1-infected patients
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Presented at; Apr 24-28; Amsterdam
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Everson GT, Sims KD, Rodriguez-Torres M. Interim analysis of an interferon (IFN)-and ribavirin (RBV)-free regimen of daclatasvir (DCV), asunaprevir (ASV), and BMS-791325 in treatment-naive, hepatitis C virus genotype 1-infected patients. Presented at 48th Annual Meeting of the European Association for the Study of the Liver; 2013 Apr 24-28; Amsterdam
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(2013)
48th Annual Meeting of the European Association for the Study of the Liver
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Everson, G.T.1
Sims, K.D.2
Rodriguez-Torres, M.3
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31
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84902663575
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High sustained viral response at 12-and 24-week follow-up of MK-5172 with pegylated interferon alfa-2b and ribavirin (PR) in HCV genotype 1 treatment-naive non-cirrhotic patient
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Presented at; Apr 24-28; Amsterdam
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Manns M, Vierling JM, Bacon BR. High sustained viral response at 12-and 24-week follow-up of MK-5172 with pegylated interferon alfa-2b and ribavirin (PR) in HCV genotype 1 treatment-naive non-cirrhotic patient. Presented at 48th Annual Meeting of the European Association for the Study of the Liver (EASL 2013); 2013 Apr 24-28; Amsterdam
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(2013)
48th Annual Meeting of the European Association for the Study of the Liver (EASL 2013)
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Manns, M.1
Vierling, J.M.2
Bacon, B.R.3
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32
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84902663576
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ACH-2684 demonstrates potent viral suppression in genotype 1 hepatitis C patients with and without cirrhosis: Safety, pharmacokinetic, and viral kinetic analysis
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Presented at; April 24-28; Amsterdam
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Lawitz E, Hill J, Vince B. ACH-2684 demonstrates potent viral suppression in genotype 1 hepatitis C patients with and without cirrhosis: safety, pharmacokinetic, and viral kinetic analysis. Presented at 48th Annual Meeting of the European Association for the Study of the Liver; 2013 April 24-28; Amsterdam
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(2013)
48th Annual Meeting of the European Association for the Study of the Liver
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Lawitz, E.1
Hill, J.2
Vince, B.3
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33
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84865285928
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Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: A randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial
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[PMID: 22714001 DOI: 10.1016/S1473-3099(12)70138-X]
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Pol S, Ghalib RH, Rustgi VK, Martorell C, Everson GT, Tatum HA, Hézode C, Lim JK, Bronowicki JP, Abrams GA, Bräu N, Morris DW, Thuluvath PJ, Reindollar RW, Yin PD, Diva U, Hindes R, McPhee F, Hernandez D, Wind-Rotolo M, Hughes EA, Schnittman S. Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: a randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial. Lancet Infect Dis 2012; 12: 671-677 [PMID: 22714001 DOI: 10.1016/S1473-3099(12)70138-X]
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(2012)
Lancet Infect Dis
, vol.12
, pp. 671-677
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Pol, S.1
Ghalib, R.H.2
Rustgi, V.K.3
Martorell, C.4
Everson, G.T.5
Tatum, H.A.6
Hézode, C.7
Lim, J.K.8
Bronowicki, J.P.9
Abrams, G.A.10
Bräu, N.11
Morris, D.W.12
Thuluvath, P.J.13
Reindollar, R.W.14
Yin, P.D.15
Diva, U.16
Hindes, R.17
McPhee, F.18
Hernandez, D.19
Wind-Rotolo, M.20
Hughes, E.A.21
Schnittman, S.22
more..
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34
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84895905492
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Sustained virologic response with daclatasvir plus sofosbuvir ribavirin (RBV) in chronic HCV genotype (GT) 1-infected patients who previously failed telaprevir (TVR) or boceprevir (BOC)
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Presented at; Apr 24-28; Amsterdam
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Sulkowski MS, Gardiner DF, Rodriguez-Torres M. Sustained virologic response with daclatasvir plus sofosbuvir ribavirin (RBV) in chronic HCV genotype (GT) 1-infected patients who previously failed telaprevir (TVR) or boceprevir (BOC). Presented at 48th Annual Meeting of the European Association for the Study of the Liver; 2013 Apr 24-28; Amsterdam
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(2013)
48th Annual Meeting of the European Association for the Study of the Liver
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Sulkowski, M.S.1
Gardiner, D.F.2
Rodriguez-Torres, M.3
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35
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84916617259
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ELECTRON: 100% SVR rate for once-daily sofosbuvir plus ledipasvir plus ribavirin given for 12 weeks in treatment-naive and previously treated patients with HCV GT 1
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Presented at; Mar 3-6; Atlanta
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Gane EJ, Stedman CA, Hyland RH. ELECTRON: 100% SVR rate for once-daily sofosbuvir plus ledipasvir plus ribavirin given for 12 weeks in treatment-naive and previously treated patients with HCV GT 1. Presented at 20th Annual Conference on Retroviruses and Opportunistic Infections; 2013 Mar 3-6; Atlanta
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(2013)
20th Annual Conference on Retroviruses and Opportunistic Infections
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Gane, E.J.1
Stedman, C.A.2
Hyland, R.H.3
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36
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84902685412
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Available from: URL: Accessed Sep 28, 2013
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HCV NS5A Inhibitor-ACH-3102. Available from: URL: http://www.achillion.com/ACH3102. Accessed Sep 28, 2013
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HCV NS5A Inhibitor-ACH-3102
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37
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84891034985
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Safety and efficacy of interferon-free regimens of ABT-450/r, ABT-267 and ABT-333 /-ribavirin in patients with chronic genotype 1 infection: Results from the Aviator study
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Presented at Apr 24-28; Amsterdam
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Kowdley KV, Lawitz E, Poordad F. Safety and efficacy of interferon-free regimens of ABT-450/r, ABT-267 and ABT-333 /-ribavirin in patients with chronic genotype 1 infection: results from the Aviator study. Presented at 48th Annual Meeting of the European Association for the Study of the Liver (EASL 2013); 2013 Apr 24-28; Amsterdam
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(2013)
48th Annual Meeting of the European Association for the Study of the Liver (EASL 2013)
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Kowdley, K.V.1
Lawitz, E.2
Poordad, F.3
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38
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84877730954
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Sofosbuvir for previously untreated chronic hepatitis C infection
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[PMID: 23607594 DOI: 10.1056/NEJMoa1214853]
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Lawitz E, Mangia A, Wyles D, Rodriguez-Torres M, Hassanein T, Gordon SC, Schultz M, Davis MN, Kayali Z, Reddy KR, Jacobson IM, Kowdley KV, Nyberg L, Subramanian GM, Hyland RH, Arterburn S, Jiang D, McNally J, Brainard D, Symonds WT, McHutchison JG, Sheikh AM, Younossi Z, Gane EJ. Sofosbuvir for previously untreated chronic hepatitis C infection. N Engl J Med 2013; 368: 1878-1887 [PMID: 23607594 DOI: 10.1056/NEJMoa1214853]
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(2013)
N Engl J Med
, vol.368
, pp. 1878-1887
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Lawitz, E.1
Mangia, A.2
Wyles, D.3
Rodriguez-Torres, M.4
Hassanein, T.5
Gordon, S.C.6
Schultz, M.7
Davis, M.N.8
Kayali, Z.9
Reddy, K.R.10
Jacobson, I.M.11
Kowdley, K.V.12
Nyberg, L.13
Subramanian, G.M.14
Hyland, R.H.15
Arterburn, S.16
Jiang, D.17
McNally, J.18
Brainard, D.19
Symonds, W.T.20
McHutchison, J.G.21
Sheikh, A.M.22
Younossi, Z.23
Gane, E.J.24
more..
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39
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84877739274
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Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options
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[PMID: 23607593 DOI: 10.1056/NEJMoa1214854]
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Jacobson IM, Gordon SC, Kowdley KV, Yoshida EM, Rodriguez-Torres M, Sulkowski MS, Shiffman ML, Lawitz E, Everson G, Bennett M, Schiff E, Al-Assi MT, Subramanian GM, An D, Lin M, McNally J, Brainard D, Symonds WT, McHutchison JG, Patel K, Feld J, Pianko S, Nelson DR. Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options. N Engl J Med 2013; 368: 1867-1877 [PMID: 23607593 DOI: 10.1056/NEJMoa1214854]
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(2013)
N Engl J Med
, vol.368
, pp. 1867-1877
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Jacobson, I.M.1
Gordon, S.C.2
Kowdley, K.V.3
Yoshida, E.M.4
Rodriguez-Torres, M.5
Sulkowski, M.S.6
Shiffman, M.L.7
Lawitz, E.8
Everson, G.9
Bennett, M.10
Schiff, E.11
Al-Assi, M.T.12
Subramanian, G.M.13
An, D.14
Lin, M.15
McNally, J.16
Brainard, D.17
Symonds, W.T.18
McHutchison, J.G.19
Patel, K.20
Feld, J.21
Pianko, S.22
Nelson, D.R.23
more..
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40
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84881025292
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JUMP-C: A randomized trial of mericitabine plus pegylated interferon alpha-2a/ribavirin for 24 weeks in treatment-naïve HCV genotype 1/4 patients
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[PMID: 23359491 DOI: 10.1002/ hep.26275]
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Pockros PJ, Jensen D, Tsai N, Taylor R, Ramji A, Cooper C, Dickson R, Tice A, Kulkarni R, Vierling JM, Lou Munson M, Chen YC, Najera I, Thommes J. JUMP-C: a randomized trial of mericitabine plus pegylated interferon alpha-2a/ribavirin for 24 weeks in treatment-naïve HCV genotype 1/4 patients. Hepatology 2013; 58: 514-523 [PMID: 23359491 DOI: 10.1002/ hep.26275]
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(2013)
Hepatology
, vol.58
, pp. 514-523
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Pockros, P.J.1
Jensen, D.2
Tsai, N.3
Taylor, R.4
Ramji, A.5
Cooper, C.6
Dickson, R.7
Tice, A.8
Kulkarni, R.9
Vierling, J.M.10
Lou Munson, M.11
Chen, Y.C.12
Najera, I.13
Thommes, J.14
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41
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84871765489
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Exploratory study of oral combination antiviral therapy for hepatitis C
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[PMID: 23281975 DOI: 10.1056/NEJMoa1208809]
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Poordad F, Lawitz E, Kowdley KV, Cohen DE, Podsadecki T, Siggelkow S, Heckaman M, Larsen L, Menon R, Koev G, Tripathi R, Pilot-Matias T, Bernstein B. Exploratory study of oral combination antiviral therapy for hepatitis C. N Engl J Med 2013; 368: 45-53 [PMID: 23281975 DOI: 10.1056/NEJMoa1208809]
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(2013)
N Engl J Med
, vol.368
, pp. 45-53
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Poordad, F.1
Lawitz, E.2
Kowdley, K.V.3
Cohen, D.E.4
Podsadecki, T.5
Siggelkow, S.6
Heckaman, M.7
Larsen, L.8
Menon, R.9
Koev, G.10
Tripathi, R.11
Pilot-Matias, T.12
Bernstein, B.13
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42
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84878781682
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Evaluation of an EMG bioimpedance measurement system for recording and analysing the pharyngeal phase of swallowing
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[PMID: 23440435 DOI: 10.2147/DDDT.S30946]
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Schultheiss C, Schauer T, Nahrstaedt H, Seidl RO. Evaluation of an EMG bioimpedance measurement system for recording and analysing the pharyngeal phase of swallowing. Eur Arch Otorhinolaryngol 2013; 270: 2149-2156 [PMID: 23440435 DOI: 10.2147/DDDT.S30946]
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(2013)
Eur Arch Otorhinolaryngol
, vol.270
, pp. 2149-2156
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Schultheiss, C.1
Schauer, T.2
Nahrstaedt, H.3
Seidl, R.O.4
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44
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84877258007
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Treatment of HCV infection by targeting microRNA
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[PMID: 23534542 DOI: 10.1056/NEJMoa1209026]
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Janssen HL, Reesink HW, Lawitz EJ, Zeuzem S, Rodriguez-Torres M, Patel K, van der Meer AJ, Patick AK, Chen A, Zhou Y, Persson R, King BD, Kauppinen S, Levin AA, Hodges MR. Treatment of HCV infection by targeting microRNA. N Engl J Med 2013; 368: 1685-1694 [PMID: 23534542 DOI: 10.1056/NEJMoa1209026]
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(2013)
N Engl J Med
, vol.368
, pp. 1685-1694
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Janssen, H.L.1
Reesink, H.W.2
Lawitz, E.J.3
Zeuzem, S.4
Rodriguez-Torres, M.5
Patel, K.6
van der Meer, A.J.7
Patick, A.K.8
Chen, A.9
Zhou, Y.10
Persson, R.11
King, B.D.12
Kauppinen, S.13
Levin, A.A.14
Hodges, M.R.15
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45
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84902663571
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Peginterferon lambda-1a (Lambda) compared to peginterferon alpha-2a (Alfa) in treatment-naïve patients with HCV genotypes (GT) 1 or 4: SVR24 results from EMERGE Phase 2b
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Presented at; Nov 9-12; Boston, MA
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Muir A, Hillson J, Gray T. Peginterferon lambda-1a (Lambda) compared to peginterferon alpha-2a (Alfa) in treatment-naïve patients with HCV genotypes (GT) 1 or 4: SVR24 results from EMERGE Phase 2b. Presented at 63rd Annual Meeting of the American Association for the Study of Liver Diseases; 2012 Nov 9-12; Boston, MA
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(2012)
63rd Annual Meeting of the American Association for the Study of Liver Diseases
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Muir, A.1
Hillson, J.2
Gray, T.3
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