Anti-neutrophil antibody enhances the neuroprotective effects of G-CSF by decreasing number of neutrophils in hypoxic ischemic neonatal rat model

Neurobiology of Disease

Volumn 69, Issue , 2014, Pages 192-199

  Doycheva, Desislava M ^a   Hadley, Tiffany ^a   Li, Li ^a   Applegate, Richard L ^a   Zhang, John H ^a   Tang, Jiping ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anti neutrophil antibody (Ab); Granulocyte colony stimulating factor (G CSF); Hypoxia ischemia (HI); Neonatal; Neurological function; Neutrophil

Indexed keywords

GRANULOCYTE ANTIBODY; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; ANTIBODY; GRANULOCYTE COLONY STIMULATING FACTOR; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ATROPHY; BRAIN INFARCTION SIZE; BRAIN WEIGHT; CAROTID ARTERY LIGATION; CONTROLLED STUDY; DRUG POTENTIATION; FEMALE; HYPOXIC ISCHEMIC ENCEPHALOPATHY; LUNG HEMORRHAGE; LUNG WEIGHT; MALE; NERVOUS SYSTEM FUNCTION; NEUROPROTECTION; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN WEIGHT; WEIGHT GAIN; ANIMAL; ATROPHY; BLOOD; BRAIN; CONVALESCENCE; DISEASE MODEL; DRUG EFFECTS; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOLOGY; LEUKOCYTE COUNT; LUNG; MULTIMODALITY CANCER THERAPY; NEUTROPHIL; NEWBORN; PATHOLOGY; PHYSIOLOGY; RANDOMIZATION; SEVERITY OF ILLNESS INDEX; SPLEEN; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; ATROPHY; BRAIN; COMBINED MODALITY THERAPY; DISEASE MODELS, ANIMAL; GRANULOCYTE COLONY-STIMULATING FACTOR; HYPOXIA-ISCHEMIA, BRAIN; LEUKOCYTE COUNT; LUNG; NEUROPROTECTIVE AGENTS; NEUTROPHILS; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SEVERITY OF ILLNESS INDEX; SPLEEN;

EID: 84902656270     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.05.024     Document Type: Article

References (57)

1. Agarwal R., et al. Post-resuscitation management of asphyxiated neonates. Indian J Pediatr 2008, 75(2):175-180.
2. Barone F.C., et al. Polymorphonuclear leukocyte infiltration into cerebral focal ischemic tissue: myeloperoxidase activity assay and histologic verification. J. Neurosci. Res. 1991, 29(3):336-345.
3. Barth T.M., Stanfield B.B. The recovery of forelimb-placing behavior in rats with neonatal unilateral cortical damage involves the remaining hemisphere. J. Neurosci. 1990, 10(10):3449-3459.
4. Beck H., et al. Participation of bone marrow-derived cells in long-term repair processes after experimental stroke. J. Cereb. Blood Flow Metab. 2003, 23(6):709-717.
5. Bracewell M., Marlow N. Patterns of motor disability in very preterm children. Ment. Retard. Dev. Disabil. Res. Rev. 2002, 8(4):241-248.
6. Broudy V.C., et al. Human umbilical vein endothelial cells display high-affinity c-kit receptors and produce a soluble form of the c-kit receptor. Blood 1994, 83(8):2145-2152.
7. Dehler M., et al. Hypoxia causes permeability oedema in the constant-pressure perfused rat lung. Eur. Respir. J. 2006, 27(3):600-606.
8. del Zoppo G.J., Mabuchi T. Cerebral microvessel responses to focal ischemia. J. Cereb. Blood Flow Metab. 2003, 23(8):879-894.
9. Fathali N., et al. Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Intensive Care Med. 2010, 36(9):1602-1608.
10. Fathali N., et al. Splenic immune cells in experimental neonatal hypoxia-ischemia. Transl. Stroke Res. 2013, 4(2):208-219.
11. Ferriero D.M. Neonatal brain injury. N. Engl. J. Med. 2004, 351(19):1985-1995.
12. Friedrich V., et al. Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage. J. Neuroinflammation 2011, 8:103.
13. Garcia J.H., et al. Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat). Am. J. Pathol. 1994, 144(1):188-199.
14. Garcia J.H., et al. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 1995, 26(4):627-634. (discussion 635).
15. Gibson C.L., et al. G-CSF suppresses edema formation and reduces interleukin-1beta expression after cerebral ischemia in mice. J. Neuropathol. Exp. Neurol. 2005, 64(9):763-769.
16. Hartman M., Warren L.H. Explaining age differences in temporal working memory. Psychol. Aging 2005, 20(4):645-656.
17. Heinel L.A., et al. Leukocyte involvement in cerebral infarct generation after ischemia and reperfusion. Brain Res. Bull. 1994, 34(2):137-141.
18. Hess D.A., et al. Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor. Blood 2002, 100(3):869-878.
19. Hess D.C., et al. Hematopoietic origin of microglial and perivascular cells in brain. Exp. Neurol. 2004, 186(2):134-144.
20. Hubel K., Engert A. Clinical applications of granulocyte colony-stimulating factor: an update and summary. Ann. Hematol. 2003, 82(4):207-213.
21. Hubel K., Engert A. Granulocyte transfusion therapy for treatment of infections after cytotoxic chemotherapy. Onkologie 2003, 26(1):73-79.
22. Hudome S., et al. The role of neutrophils in the production of hypoxic-ischemic brain injury in the neonatal rat. Pediatr. Res. 1997, 41(5):607-616.
23. Justicia C., et al. Neutrophil infiltration increases matrix metalloproteinase-9 in the ischemic brain after occlusion/reperfusion of the middle cerebral artery in rats. J. Cereb. Blood Flow Metab. 2003, 23(12):1430-1440.
24. Kim B.R., et al. Granulocyte stimulating factor attenuates hypoxic-ischemic brain injury by inhibiting apoptosis in neonatal rats. Yonsei Med. J. 2008, 49(5):836-842.
25. Kocher A.A., et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat. Med. 2001, 7(4):430-436.
26. Koenigsberger M.R. Advances in neonatal neurology: 1950-2000. Rev. Neurol. 2000, 31(3):202-211.
27. Komine-Kobayashi M., et al. Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice. J. Cereb. Blood Flow Metab. 2006, 26(3):402-413.
28. Lees K.R., et al. UK-279,276, a neutrophil inhibitory glycoprotein, in acute stroke: tolerability and pharmacokinetics. Stroke 2003, 34(7):1704-1709.
29. Lodha A., et al. Role of hemocoagulase in pulmonary hemorrhage in preterm infants: a systematic review. Indian J. Pediatr. 2011, 78(7):838-844.
30. Matchett G.A., et al. The effect of granulocyte-colony stimulating factor in global cerebral ischemia in rats. Brain Res. 2007, 1136(1):200-207.
31. Matsuo Y., et al. Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat. Effects of neutrophil depletion. Stroke 1994, 25(7):1469-1475.
32. Ostrowski R.P., Colohan A.R., Zhang J.H. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J. Cereb. Blood Flow Metab. 2005, 25(5):554-571.
33. Popa-Wagner A., et al. Effects of granulocyte-colony stimulating factor after stroke in aged rats. Stroke 2010, 41(5):1027-1031.
34. Powell T.M., et al. Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 2005, 25(2):296-301.
35. Rice J.E., Vannucci R.C., Brierley J.B. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann. Neurol. 1981, 9(2):131-141.
36. Roberts A.W. G-CSF: a key regulator of neutrophil production, but that's not all!. Growth Factors 2005, 23(1):33-41.
37. Sayeed I., Wali B., Stein D.G. Progesterone inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. Restor. Neurol. Neurosci. 2007, 25(2):151-159.
38. Schabitz W.R., et al. Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia. Stroke 2003, 34(3):745-751.
39. Schabitz W.R., et al. AXIS: a trial of intravenous granulocyte colony-stimulating factor in acute ischemic stroke. Stroke 2010, 41(11):2545-2551.
40. Schneider A., et al. The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J. Clin. Invest. 2005, 115(8):2083-2098.
41. Shiga Y., et al. Neutrophil as a mediator of ischemic edema formation in the brain. Neurosci. Lett. 1991, 125(2):110-112.
42. Shimakura A., et al. Neutrophil elastase inhibition reduces cerebral ischemic damage in the middle cerebral artery occlusion. Brain Res. 2000, 858(1):55-60.
43. Shyu W.C., et al. Granulocyte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial. CMAJ 2006, 174(7):927-933.
44. Solaroglu I., et al. Anti-apoptotic effect of granulocyte-colony stimulating factor after focal cerebral ischemia in the rat. Neuroscience 2006, 143(4):965-974.
45. Solaroglu I., et al. Granulocyte colony-stimulating factor protects the brain against experimental stroke via inhibition of apoptosis and inflammation. Neurol. Res. 2009, 31(2):167-172.
46. Spandou E., et al. Erythropoietin prevents long-term sensorimotor deficits and brain injury following neonatal hypoxia-ischemia in rats. Brain Res. 2005, 1045(1-2):22-30.
47. Sprigg N., et al. Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the stem cell trial of recovery enhancement after stroke (STEMS) pilot randomized, controlled trial (ISRCTN 16784092). Stroke 2006, 37(12):2979-2983.
48. Stoll G., Jander S., Schroeter M. Inflammation and glial responses in ischemic brain lesions. Prog. Neurobiol. 1998, 56(2):149-171.
49. Swenson E.R., et al. Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor. JAMA 2002, 287(17):2228-2235.
50. Takamiya M., et al. Granulocyte colony-stimulating factor-mobilized circulating c-Kit+/Flk-1+ progenitor cells regenerate endothelium and inhibit neointimal hyperplasia after vascular injury. Arterioscler. Thromb. Vasc. Biol. 2006, 26(4):751-757.
51. van Raam B.J., et al. Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3. Blood 2008, 112(5):2046-2054.
52. Vannucci R.C., Vannucci S.J. A model of perinatal hypoxic-ischemic brain damage. Ann. N. Y. Acad. Sci. 1997, 835:234-249.
53. Vemuganti R., Dempsey R.J., Bowen K.K. Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat. Stroke 2004, 35(1):179-184.
54. Volpe J.J. Perinatal brain injury: from pathogenesis to neuroprotection. Ment. Retard. Dev. Disabil. Res. Rev. 2001, 7(1):56-64.
55. Yata K., et al. Granulocyte-colony stimulating factor inhibits apoptotic neuron loss after neonatal hypoxia-ischemia in rats. Brain Res. 2007, 1145:227-238.
56. Zanelli S., Naylor M., Kapur J. Nitric oxide alters GABAergic synaptic transmission in cultured hippocampal neurons. Brain Res. 2009, 1297:23-31.
57. Zhao L.R., et al. Hematopoietic growth factors pass through the blood-brain barrier in intact rats. Exp. Neurol. 2007, 204(2):569-573.