Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILRα

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 24, 2014, Pages 8877-8882

  Kuroki, Kimiko ^a   Wang, Jing ^b,f   Ose, Toyoyuki ^a   Yamaguchi, Munechika ^c   Tabata, Shigekazu ^c   Maita, Nobuo ^c   Nakamura, Seiko ^c   Kajikawa, Mizuho ^c   Kogure, Amane ^b,g   Satoh, Takeshi ^b,h   Arase, Hisashi ^b,d,e   Maenaka, Katsumi ^a,e  

^a HOKKAIDO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f UNIVERSITY OF CALGARY   (Canada)

^g KYOTO UNIVERSITY   (Japan)

^h INSERM   (France)

Author keywords

Immune regulation; O glycosylated protein; Paired receptor; X ray crystallography

Indexed keywords

GLYCAN; GLYCOSYLATED PROTEIN; LIGAND; MUCIN; PAIRED IMMUNOGLOBULIN LIKE TYPE 2 RECEPTOR ALPHA; PROLINE; RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HERPES SIMPLEX VIRUS 1; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN STRUCTURE; RECEPTOR BINDING; VIRUS ENTRY;

IMMUNE REGULATION; O-GLYCOSYLATED PROTEIN; PAIRED RECEPTOR; X-RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CRYSTALLOGRAPHY, X-RAY; GLYCOSYLATION; HEK293 CELLS; HUMANS; IMMUNE SYSTEM; MEMBRANE GLYCOPROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUCINS; MUTAGENESIS; PEPTIDES; POLYSACCHARIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, IMMUNOLOGIC; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SURFACE PLASMON RESONANCE;

EID: 84902593774     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1324105111     Document Type: Article

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