Characterization of CTX-M-14- and CTX-M-15-producing escherichia coli and klebsiella pneumoniae isolates from urine specimens in a tertiary-care hospital

Journal of Microbiology and Biotechnology

Volumn 24, Issue 6, 2014, Pages 765-770

  Kim, Semi ^a   Sung, Ji Youn ^b   Cho, Hye Hyun ^c   Kwon, Kye Chul ^a   Koo, Sun Hoe ^a  

^a Chungnam National University   (South Korea)

^b Far East University   (South Korea)

^c Jeonju Kijeon College   (South Korea)

Author keywords

CTX M 14, CTX M 15; E. coli; Extended spectrum lactamase (ESBL); K. pneumoniae

Indexed keywords

AMIKACIN; BETA LACTAMASE CTX M; BETA LACTAMASE CTX M 14; BETA LACTAMASE CTX M 15; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; GENTAMICIN; LEVOFLOXACIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE; BETA-LACTAMASE CTX-M-14; BETA-LACTAMASE CTX-M-15;

ANTIBIOTIC RESISTANCE; ARMA GENE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; ENZYME ASSAY; ENZYME SYNTHESIS; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING ESCHERICHIA COLI; GNR GENE; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; TERTIARY CARE CENTER; URINALYSIS; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE; STATISTICS AND NUMERICAL DATA; URINE;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; TERTIARY CARE CENTERS; URINE;

EID: 84902581133     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1306.06036     Document Type: Article

References (28)

1. Cattoir V, Poirel L, Rotimi V, Soussy CJ, Nordmann P. 2007. Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J. Antimicrob. Chemother. 60: 394-397.
2. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; sixteenth informational supplement. M100-S16. Wayne, Pensylvania: CLSI, 2006.
3. Duan H, Chai T, Liu J, Zhang X, Qi C, Gao J, et al. 2009. Source identification of airborne Escherichia coli o f swine house surroundings using ERIC-PCR and REP-PCR. Environ. Res. 109: 511-517.
4. Dhanji H, Doumith M, Rooney PJ, O'Leary MC, Loughrey AC, Hope R, et al. 2011. Molecular epidemiology of fluoroquinolone-resistant ST131 Escherichia coli producing CTX-M extended-spectrum beta-lactamases in nursing homes in Belfast, UK. J. Antimicrob. Chemother. 66: 297-303.
5. Jeong HS, Bae IK, Shin JH, Jung HJ, Kim SH, Lee JY, et al. 2011. Prevalence of plasmid-mediated quinolone resistance and its association with extended-spectrum beta-lactamase and AmpC beta-lactamase in Enterobacteriaceae. Korean J. Lab. Med. 31: 257-264.
6. Kang HY, Kim J, Seol SY, Lee YC, Lee JC, Cho DT. 2009. Characterization of conjugative plasmids carrying antibiotic resistance genes encoding 16S rRNA methylase, extendedspectrum beta-lactamase, and/or plasmid-mediated AmpC beta-lactamase. J. Microbiol. 47: 68-75.
7. Kim HB, Park CH, Kim CJ, Kim EC, Jacoby GA, Hooper DC. 2009. Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period. Antimicrob. Agents Chemother. 53: 639-645.
8. Kim J, Bae IK, Jeong SH, Chang CL, Lee CH, Lee K. 2011. Characterization of IncF plasmids carrying the blaCTX-M-14 gene in clinical isolates of Escherichia coli from Korea. J. Antimicrob. Chemother. 66: 1263-1268.
9. Kim MH, Lee HJ, Park KS, Suh JT. 2010. Molecular characteristics of extended spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae and the prevalence of qnr in extended spectrum beta-lactamase isolates in a tertiary care hospital in Korea. Yonsei Med. J. 51: 768-774.
10. Kim MH, Sung JY, Park JW, Kwon GC, Koo SH. 2007. Coproduction of qnrB and armA from extended-spectrum beta-lactamase-producing Klebsiella pneumoniae. Korean J. Lab. Med. 27: 428-436.
11. Ko KS, Lee MY, Song JH, Lee H, Jung DS, Jung SI, et al. 2008. Prevalence and characterization of extended-spectrum beta-lactamase-producing Enterobacteriaceae isolated in Korean hospitals. Diagn. Microbiol. Infect. Dis. 61: 453-459.
12. Lewis JS 2nd, Herrera M, Wickes B, Patterson JE, Jorgensen JH. 2007. First report of the emergence of CTX-M-type extended-spectrum beta-lactamases (ESBLs) as the predominant ESBL isolated in a US health care system. Antimicrob. Agents Chemother. 51: 4015-4021.
13. Li XM, Jang SJ, Bae IK, Park G, Kim YS, Shin JH, et al. 2010. Frequency of extended-spectrum β-lactamase (ESBL) and AmpC β-lactamase genes in Escherichia coli and Klebsiella pneumoniae over a three-year period in a University Hospital in Korea. Korean J. Lab. Med. 30: 616-623.
14. Park SD, Uh Y, Lee G, Lim K, Kim JB, Jeong SH. 2010. Prevalence and resistance patterns of extended-spectrum and AmpC β-lactamase in Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Salmonella serovar Stanley in a Korean tertiary hospital. APMIS 118: 801-808.
15. Park SH, Byun JH, Choi SM, Lee DG, Kim SH, Kwon JC, et al. 2012. Molecular epidemiology of extended-spectrum β- lactamase-producing Escherichia coli in the community and hospital in Korea: emergence of ST131 producing CTX-M- 15. BMC Infect. Dis. 12: 149.
16. Park Y, Kang HK, Bae IK, Kim J, Kim JS, Uh Y, et al. 2009. Prevalence of the extended-spectrum beta-lactamase and qnr genes in clinical isolates of Escherichia coli. Korean J. Lab. Med. 29: 218-223.
17. Paterson DL. 2006. Resistance in gram-negative bacteria: Enterobacteriaceae. Am. J. Med. 119: S20-S28; discussion S62-S70.
18. Pérez-Pérez FJ, Hanson ND. 2002. Detection of plasmidmediated AmpC beta-lactamase genes in clinical isolates by using multiplex PCR. J. Clin. Microbiol. 40: 2153-2162.
19. Piatti G, Mannini A, Balistreri M, Schito AM. 2008. Virulence factors in urinary Escherichia coli strains: phylogenetic background and quinolone and fluoroquinolone resistance. J. Clin. Microbiol. 46: 480-487.
20. Podschun R, Ullmann U. 1998. Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin. Microbiol. Rev. 11: 589-603.
21. Rossolini GM, D'Andrea MM, Mugnaioli C. 2008. The spread of CTX-M-type extended-spectrum beta-lactamases. Clin. Microbiol. Infect. 14(Suppl 1): 33-41.
22. Ruiz E, Sáenz Y, Zarazaga M, Rocha-Gracia R, Martínez- Martínez L, Arlet G, Torres C. 2012. qnr, aac(6')-Ib-cr and qepA genes in Escherichia coli and Klebsiella spp.: genetic environments and plasmid and chromosomal location. J. Antimicrob. Chemother. 67: 886-897.
23. Shin J, Kim DH, Ko KS. 2011. Comparison of CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae isolates from patients with bacteremia. J. Infect. 63: 39-47.
24. Seo MR, Park YS, Pai H. 2010. Characteristics of plasmidmediated quinolone resistance genes in extended-spectrum cephalosporin-resistant isolates of Klebsiella pneumoniae and Escherichia coli in Korea. Chemotherapy 56: 46-53.
25. Song S, Lee EY, Koh EM, Ha HS, Jeong HJ, Bae IK, Jeong SH. 2009. Antibiotic resistance mechanisms of Escherichia coli isolates from urinary specimens. Korean J. Lab. Med. 29: 17-24.
26. Sung JY, Koo SH, Kwon KC, Park JW, Ko CS, Shin SY, Song JH. 2009. Characterization o f class 1 integrons in metallo-β- lactamase-producing Pseudomonas aeruginosa. Korean J. Clin. Microbiol. 12: 17-23.
27. Yoo JS, Byeon J, Yang J, Yoo JI, Chung GT, Lee YS. 2010. High prevalence of extended-spectrum beta-lactamases and plasmid-mediated AmpC beta-lactamases in Enterobacteriaceae isolated from long-term care facilities in Korea. Diagn. Microbiol. Infect. Dis. 67: 261-265.
28. Yum JH, Kim S, Lee H, Yong D, Lee K, Cho SN, Chong Y. 2005. Emergence and wide dissemination of CTX-M-type ESBLs, and CMY-2- and DHA-1-type AmpC beta-lactamases in Korean respiratory isolates of Klebsiella pneumoniae. J. Korean Med. Sci. 20: 961-965.