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Volumn 49, Issue , 2014, Pages 282-291

Formalizing MedDRA to support semantic reasoning on adverse drug reaction terms

Author keywords

Adverse drug reaction; MedDRA; Ontology; Semantic reasoning; SNOMED CT; Terminology

Indexed keywords

ONTOLOGY; PHARMACODYNAMICS;

EID: 84902553209     PISSN: 15320464     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbi.2014.03.012     Document Type: Article
Times cited : (26)

References (53)
  • 1
    • 84902546041 scopus 로고    scopus 로고
    • ICH guideline E2B (R2)
    • Electronic transmission of individual case safety reports - Message specification (ICH ICSR DTD Version 2.1), Final Version 2.3, Document Revision February 1
    • ICH guideline E2B (R2), Electronic transmission of individual case safety reports - Message specification (ICH ICSR DTD Version 2.1), Final Version 2.3, Document Revision February 1, 2001.
    • (2001)
  • 2
    • 84902538990 scopus 로고    scopus 로고
    • MedDRA MSSO website. <>.
    • MedDRA MSSO website. <>. http://www.meddramsso.com/.
  • 3
    • 0037218258 scopus 로고    scopus 로고
    • Methods and pitfalls in searching drug safety databases utilising the medical dictionary for regulatory activities (MedDRA)
    • Brown E.G. Methods and pitfalls in searching drug safety databases utilising the medical dictionary for regulatory activities (MedDRA). Drug Saf 2003, 26(3):145-158.
    • (2003) Drug Saf , vol.26 , Issue.3 , pp. 145-158
    • Brown, E.G.1
  • 4
    • 3042609851 scopus 로고    scopus 로고
    • Using MedDRA
    • Brown E.G. Using MedDRA. Drug saf 2004, 27(8):591-602.
    • (2004) Drug saf , vol.27 , Issue.8 , pp. 591-602
    • Brown, E.G.1
  • 5
    • 84902538991 scopus 로고    scopus 로고
    • MedDRA Data Retrieval and Presentation: Points to Consider. ICH-Endorsed Guide for MedDRA Users on Data Output. Release 3.2, based on MedDRA Version 14.1. 1 October
    • MedDRA Data Retrieval and Presentation: Points to Consider. ICH-Endorsed Guide for MedDRA Users on Data Output. Release 3.2, based on MedDRA Version 14.1. 1 October 2011.
    • (2011)
  • 6
    • 34447124478 scopus 로고    scopus 로고
    • Standardised MedDRA queries: their role in signal detection
    • Mozzicato P. Standardised MedDRA queries: their role in signal detection. Drug Saf 2007, 30(7):617-619.
    • (2007) Drug Saf , vol.30 , Issue.7 , pp. 617-619
    • Mozzicato, P.1
  • 7
    • 12544259120 scopus 로고    scopus 로고
    • Appraisal of the MedDRA conceptual structure for describing and grouping adverse drug reactions
    • Bousquet C., Lagier G., Lillo-Le Louët A., Le Beller C., Venot A., Jaulent M.C. Appraisal of the MedDRA conceptual structure for describing and grouping adverse drug reactions. Drug Saf 2005, 28(1):19-34.
    • (2005) Drug Saf , vol.28 , Issue.1 , pp. 19-34
    • Bousquet, C.1    Lagier, G.2    Lillo-Le Louët, A.3    Le Beller, C.4    Venot, A.5    Jaulent, M.C.6
  • 8
    • 73949143754 scopus 로고    scopus 로고
    • The MedDRA paradox
    • Merrill G. The MedDRA paradox. AMIA Annu Symp Proc 2008, 6:470-474.
    • (2008) AMIA Annu Symp Proc , vol.6 , pp. 470-474
    • Merrill, G.1
  • 9
    • 0036376662 scopus 로고    scopus 로고
    • Adverse event reporting and standardized medical terminologies: strengths and limitations
    • Goldman S.A. Adverse event reporting and standardized medical terminologies: strengths and limitations. Drug Inf J 2002, 36(2):439-444.
    • (2002) Drug Inf J , vol.36 , Issue.2 , pp. 439-444
    • Goldman, S.A.1
  • 10
    • 49749090086 scopus 로고    scopus 로고
    • Heterogeneous but "standard" coding systems for adverse events: issues in achieving interoperability between apples and oranges
    • Richesson R.L., Fung K.W., Krischer J.P. Heterogeneous but "standard" coding systems for adverse events: issues in achieving interoperability between apples and oranges. Contemp Clin Trials 2008, 29(5):635.
    • (2008) Contemp Clin Trials , vol.29 , Issue.5 , pp. 635
    • Richesson, R.L.1    Fung, K.W.2    Krischer, J.P.3
  • 11
    • 77958610135 scopus 로고    scopus 로고
    • Determining correspondences between highfrequency MedDRA concepts and SNOMED: a case study
    • Nadkarni P.M., Darer J.A. Determining correspondences between highfrequency MedDRA concepts and SNOMED: a case study. BMC Med Inform Decis Mak 2010, 10:66.
    • (2010) BMC Med Inform Decis Mak , vol.10 , pp. 66
    • Nadkarni, P.M.1    Darer, J.A.2
  • 12
    • 0032418859 scopus 로고    scopus 로고
    • Standards to support development of terminological systems for healthcare telematics
    • Rossi Mori A., Consorti F., Galeazzi E. Standards to support development of terminological systems for healthcare telematics. Methods Inform Med 1998, 37:551-563.
    • (1998) Methods Inform Med , vol.37 , pp. 551-563
    • Rossi Mori, A.1    Consorti, F.2    Galeazzi, E.3
  • 13
    • 84902538992 scopus 로고    scopus 로고
    • MedDRA Introductory Guide Version 14.0. MSSO-DI-6003-14.0.0. March
    • MedDRA Introductory Guide Version 14.0. MSSO-DI-6003-14.0.0. March 2011.
    • (2011)
  • 14
    • 84902538983 scopus 로고    scopus 로고
    • MedDRA Term Selection: Points to Consider. ICH-Endorsed Guide for MedDRA Users. Release 4.5, based on MedDRA Version 16.0. 1 April
    • MedDRA Term Selection: Points to Consider. ICH-Endorsed Guide for MedDRA Users. Release 4.5, based on MedDRA Version 16.0. 1 April 2013.
    • (2013)
  • 16
    • 0034852799 scopus 로고    scopus 로고
    • Using MedDRA for adverse events in cancer trials: experience, caveats, and advice
    • Tremmel L., Scarpone L. Using MedDRA for adverse events in cancer trials: experience, caveats, and advice. Drug Inf J 2001, 35:845-852.
    • (2001) Drug Inf J , vol.35 , pp. 845-852
    • Tremmel, L.1    Scarpone, L.2
  • 17
    • 84864113283 scopus 로고    scopus 로고
    • Challenges in coding adverse events in clinical trials: a systematic review
    • Schroll J.B., Maund E., Gøtzsche P.C. Challenges in coding adverse events in clinical trials: a systematic review. PLoS ONE 2012, 7(7):e41174.
    • (2012) PLoS ONE , vol.7 , Issue.7
    • Schroll, J.B.1    Maund, E.2    Gøtzsche, P.C.3
  • 18
    • 35048878443 scopus 로고    scopus 로고
    • The role of foundational ontologies in manufacturing domains
    • Borgo S., Leitao P. The role of foundational ontologies in manufacturing domains. Lecture Notes Comput Sci 2004, 3290:670-688.
    • (2004) Lecture Notes Comput Sci , vol.3290 , pp. 670-688
    • Borgo, S.1    Leitao, P.2
  • 19
    • 33644502245 scopus 로고    scopus 로고
    • The role of ontologies in data integration
    • Cruz I.F., Huiyong X. The role of ontologies in data integration. Eng Intell Syst Elect 2005, 13(4):245-252.
    • (2005) Eng Intell Syst Elect , vol.13 , Issue.4 , pp. 245-252
    • Cruz, I.F.1    Huiyong, X.2
  • 20
    • 84902538984 scopus 로고    scopus 로고
    • WonderWeb Deliverable D18 Ontology Library (final). Internal report, IST Project 2001-33052 WonderWeb: Ontology Infrastructure for the, Semantic Web
    • Masolo C, Borgo S, Gangemi A, Guarino N, Oltramaria A. WonderWeb Deliverable D18 Ontology Library (final). Internal report, IST Project 2001-33052 WonderWeb: Ontology Infrastructure for the, Semantic Web; 2003.
    • (2003)
    • Masolo, C.1    Borgo, S.2    Gangemi, A.3    Guarino, N.4    Oltramaria, A.5
  • 22
    • 0010222050 scopus 로고    scopus 로고
    • Ontology-based integration of information. A survey of existing approaches. In: Stuckenschmidt H, editor. IJCAI-01 Workshop: Ontologies and Information Sharing
    • Wache H, Vögele T, Visser U, Stuckenschmidt H, Schuster G, Neumann H, Hübner S. Ontology-based integration of information. A survey of existing approaches. In: Stuckenschmidt H, editor. IJCAI-01 Workshop: Ontologies and Information Sharing 2001:108-117.
    • (2001) , pp. 108-117
    • Wache, H.1    Vögele, T.2    Visser, U.3    Stuckenschmidt, H.4    Schuster, G.5    Neumann, H.6    Hübner, S.7
  • 23
    • 22544439665 scopus 로고    scopus 로고
    • Implementation of automated signal generation in pharmacovigilance using a knowledge-based approach
    • Bousquet C., Henegar C., Lillo-Le Louet A., Degoulet P., Jaulent MC. Implementation of automated signal generation in pharmacovigilance using a knowledge-based approach. Int J Med Inform 2005, 74:563-571.
    • (2005) Int J Med Inform , vol.74 , pp. 563-571
    • Bousquet, C.1    Henegar, C.2    Lillo-Le Louet, A.3    Degoulet, P.4    Jaulent, M.C.5
  • 24
    • 0036300273 scopus 로고    scopus 로고
    • Effects of coding dictionary on signal generation: a consideration of use of MedDRA compared with WHO-ART
    • Brown E.G. Effects of coding dictionary on signal generation: a consideration of use of MedDRA compared with WHO-ART. Drug Saf 2002, 25(6):445-452.
    • (2002) Drug Saf , vol.25 , Issue.6 , pp. 445-452
    • Brown, E.G.1
  • 25
    • 0034233257 scopus 로고    scopus 로고
    • The use of a medical dictionary for regulatory activities terminology (MedDRA) in prescription-event monitoring in Japan (J-PEM)
    • Yokotsuka M., Aoyama M., Kubota K. The use of a medical dictionary for regulatory activities terminology (MedDRA) in prescription-event monitoring in Japan (J-PEM). Int J Med Inform 2000, 57(2-3):139-153.
    • (2000) Int J Med Inform , vol.57 , Issue.2-3 , pp. 139-153
    • Yokotsuka, M.1    Aoyama, M.2    Kubota, K.3
  • 26
    • 33646829762 scopus 로고    scopus 로고
    • Building an ontology of adverse drug reactions for automated signal generation in pharmacovigilance
    • Henegar C., Bousquet C., Lillo-Le Louët A., Degoulet P., Jaulent MC. Building an ontology of adverse drug reactions for automated signal generation in pharmacovigilance. Comput Biol Med 2006, 36(7-8):748-767.
    • (2006) Comput Biol Med , vol.36 , Issue.7-8 , pp. 748-767
    • Henegar, C.1    Bousquet, C.2    Lillo-Le Louët, A.3    Degoulet, P.4    Jaulent, M.C.5
  • 28
    • 84902538985 scopus 로고    scopus 로고
    • SNOMED-CT Website. <>.
    • SNOMED-CT Website. <>. http://www.ihtsdo.org/SNOMED-CT/.
  • 30
    • 84902538986 scopus 로고    scopus 로고
    • UMLS Website. <>.
    • UMLS Website. <>. http://www.nlm.nih.gov/research/umls/.
  • 31
    • 84902538987 scopus 로고    scopus 로고
    • Bioportal Website. <>.
    • Bioportal Website. <>. http://bioportal.bioontology.org/.
  • 32
    • 79953786495 scopus 로고    scopus 로고
    • Using SNOMED-CT in combination with MedDRA for reporting signal detection and adverse drug reactions reporting
    • Bodenreider O. Using SNOMED-CT in combination with MedDRA for reporting signal detection and adverse drug reactions reporting. AMIA Annu Symp Proc 2009, 14(2009):45-49.
    • (2009) AMIA Annu Symp Proc , vol.14 , Issue.2009 , pp. 45-49
    • Bodenreider, O.1
  • 33
    • 39049188968 scopus 로고    scopus 로고
    • Mapping of the WHO-ART terminology on SNOMED-CT to improve grouping of related adverse drug reactions
    • Alecu I., Bousquet C., Mougin F., Jaulent M.C. Mapping of the WHO-ART terminology on SNOMED-CT to improve grouping of related adverse drug reactions. Stud Health Technol Inform 2006, 124:833-838.
    • (2006) Stud Health Technol Inform , vol.124 , pp. 833-838
    • Alecu, I.1    Bousquet, C.2    Mougin, F.3    Jaulent, M.C.4
  • 34
    • 84964961762 scopus 로고    scopus 로고
    • The pitfalls of thesaurus ontologization. The case of the NCI thesaurus
    • Schulz S., Schober S., Tudose I., Stenzhorn H. The pitfalls of thesaurus ontologization. The case of the NCI thesaurus. AMIA Annu Symp Proc 2010, 727-731.
    • (2010) AMIA Annu Symp Proc , pp. 727-731
    • Schulz, S.1    Schober, S.2    Tudose, I.3    Stenzhorn, H.4
  • 35
    • 76649117776 scopus 로고    scopus 로고
    • Assessing applicability of ontological principles to different types of biomedical vocabularies
    • Ingenerf J., Linder R. Assessing applicability of ontological principles to different types of biomedical vocabularies. Methods Inform Med 2009, 48(5):459.
    • (2009) Methods Inform Med , vol.48 , Issue.5 , pp. 459
    • Ingenerf, J.1    Linder, R.2
  • 36
    • 0032433211 scopus 로고    scopus 로고
    • Desiderata for controlled medical vocabularies in the twenty-first century
    • Cimino J.J. Desiderata for controlled medical vocabularies in the twenty-first century. Methods Inform Med 1998, 37:394-403.
    • (1998) Methods Inform Med , vol.37 , pp. 394-403
    • Cimino, J.J.1
  • 37
    • 54449101546 scopus 로고    scopus 로고
    • Why do it the hard way? The case for an expressive description logic for SNOMED
    • Rector A., Brandt S. Why do it the hard way? The case for an expressive description logic for SNOMED. J Am Med Inform Assoc 2008, 15(6):744-751.
    • (2008) J Am Med Inform Assoc , vol.15 , Issue.6 , pp. 744-751
    • Rector, A.1    Brandt, S.2
  • 38
    • 80052095821 scopus 로고    scopus 로고
    • Consolidating SNOMED CT's ontological commitment
    • Schulz S., Cornet R., Spackman K. Consolidating SNOMED CT's ontological commitment. Appl Ontol 2011, 6(1):1-11.
    • (2011) Appl Ontol , vol.6 , Issue.1 , pp. 1-11
    • Schulz, S.1    Cornet, R.2    Spackman, K.3
  • 40
    • 84902538982 scopus 로고    scopus 로고
    • SNOMED Clinical Terms® User Guide, 2010 July International Release.
    • SNOMED Clinical Terms® User Guide, 2010 July International Release.
  • 41
    • 84902538977 scopus 로고    scopus 로고
    • EL description, W3C OWL working group. <>.
    • EL description, W3C OWL working group. <>. http://www.w3.org/2007/OWL/wiki/EL.
  • 42
    • 84902538978 scopus 로고    scopus 로고
    • OWL 2 Web Ontology Language Profiles (Second Edition), W3C Recommendation 11 December 2012. <>.
    • OWL 2 Web Ontology Language Profiles (Second Edition), W3C Recommendation 11 December 2012. <>. http://www.w3.org/TR/owl2-profiles/.
  • 43
    • 72449176909 scopus 로고    scopus 로고
    • EU-ADR group. Data mining on electronic health record databases for signal detection in pharmacovigilance. which events to monitor?
    • Trifirò G., Pariente A., Coloma P.M., Kors J.A., Polimeni G., Miremont-Salamé G., et al. EU-ADR group. Data mining on electronic health record databases for signal detection in pharmacovigilance. which events to monitor?. Pharmacoepidemiol Drug Saf 2009, 18(12):1176-1184.
    • (2009) Pharmacoepidemiol Drug Saf , vol.18 , Issue.12 , pp. 1176-1184
    • Trifirò, G.1    Pariente, A.2    Coloma, P.M.3    Kors, J.A.4    Polimeni, G.5    Miremont-Salamé, G.6
  • 44
    • 84872528219 scopus 로고    scopus 로고
    • Automatic generation of MedDRA terms groupings using an ontology
    • Declerck G., Bousquet C., Jaulent M.C. Automatic generation of MedDRA terms groupings using an ontology. Stud Health Technol Inform 2012, 180:73-77.
    • (2012) Stud Health Technol Inform , vol.180 , pp. 73-77
    • Declerck, G.1    Bousquet, C.2    Jaulent, M.C.3
  • 46
    • 33947130673 scopus 로고    scopus 로고
    • Understanding and using the meaning of statements in a bio-ontology: recasting the Gene Ontology in OWL
    • Aranguren M.E., Bechhofer S., Lord P., Sattler U., Stevens R. Understanding and using the meaning of statements in a bio-ontology: recasting the Gene Ontology in OWL. BMC Bioinform 2007, 8(1):57.
    • (2007) BMC Bioinform , vol.8 , Issue.1 , pp. 57
    • Aranguren, M.E.1    Bechhofer, S.2    Lord, P.3    Sattler, U.4    Stevens, R.5
  • 47
    • 85013602572 scopus 로고    scopus 로고
    • Representing the NCI Thesaurus in OWL DL: modeling tools help modeling languages
    • Noy N.F., de Coronado S., Solbrig H., Fragoso G., Hartel F.W., Musen M.A. Representing the NCI Thesaurus in OWL DL: modeling tools help modeling languages. Appl Ontol 2008, 3(3):173-190.
    • (2008) Appl Ontol , vol.3 , Issue.3 , pp. 173-190
    • Noy, N.F.1    de Coronado, S.2    Solbrig, H.3    Fragoso, G.4    Hartel, F.W.5    Musen, M.A.6
  • 48
    • 78651466215 scopus 로고    scopus 로고
    • Representing the International Classification of Diseases Version 10 in OWL. Proc KEOD
    • Möller M, Sintek M, Biedert R, Ernst P, Dengel A, Sonntag D. Representing the International Classification of Diseases Version 10 in OWL. Proc KEOD 2010, 50-59.
    • (2010) , pp. 50-59
    • Möller, M.1    Sintek, M.2    Biedert, R.3    Ernst, P.4    Dengel, A.5    Sonntag, D.6
  • 49
    • 84902538979 scopus 로고    scopus 로고
    • Ontology-based convergence of medical terminologies: SNOMED CT and ICD-11. In: Proceedings of the eHealth2012. 2012 May 10-11; Vienna, Austria. OCG;
    • Chute C, Üstün B, Spackman K. Ontology-based convergence of medical terminologies: SNOMED CT and ICD-11. In: Proceedings of the eHealth2012. 2012 May 10-11; Vienna, Austria. OCG; 2012.
    • (2012)
    • Chute, C.1    Üstün, B.2    Spackman, K.3
  • 51
    • 84902538980 scopus 로고    scopus 로고
    • An attempt to expedite signal detection by grouping related adverse reaction terms, Worshop "Computational methods in pharmacovigilance", In: 24th European Medical Informatics Conference (MIE 2012), 26-29 August 2012, Pisa (Italy). Drug Saf 1194-5.
    • Hill R, Hopstadius J, Lerch M, Noren N. An attempt to expedite signal detection by grouping related adverse reaction terms, Worshop "Computational methods in pharmacovigilance", In: 24th European Medical Informatics Conference (MIE 2012), 26-29 August 2012, Pisa (Italy). Drug Saf 2012; 35 (12): 1194-5.
    • (2012) , vol.35 , Issue.12
    • Hill, R.1    Hopstadius, J.2    Lerch, M.3    Noren, N.4
  • 53
    • 84981551715 scopus 로고    scopus 로고
    • Evaluation of automated term groupings for detecting upper gastrointestinal bleeding signals for drugs
    • Souvignet J., Declerck G., Jaulent M.-C., Bousquet C. Evaluation of automated term groupings for detecting upper gastrointestinal bleeding signals for drugs. Drug Saf 2012, 35(12):1195-1196.
    • (2012) Drug Saf , vol.35 , Issue.12 , pp. 1195-1196
    • Souvignet, J.1    Declerck, G.2    Jaulent, M.-C.3    Bousquet, C.4


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