Propionibacterium acnes, an emerging pathogen: From acne to implant-infections, from phylotype to resistance

Medecine et Maladies Infectieuses

Volumn 44, Issue 6, 2014, Pages 241-250

  Aubin, G G ^a,b   Portillo, M E ^c   Trampuz, A ^d   Corvec, S ^a,b  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c Laboratorio de Referencia de Catalunya   (Spain)

^d HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Acne; Antibiotic resistance; Phylotype; Prosthesis or device related infections

Indexed keywords

ANTIBIOTIC AGENT; COTRIMOXAZOLE; MACROLIDE; RIFAMPICIN; RNA POLYMERASE BETA SUBUNIT; TETRACYCLINE DERIVATIVE; ANTIINFECTIVE AGENT; BACTERIAL DNA; BACTERIAL PROTEIN;

ACNE VULGARIS; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOFILM; BONE INFECTION; BONE PROSTHESIS; BREAST IMPLANT; DEVICE INFECTION; GENE MUTATION; GENE SEQUENCE; HEART VALVE PROSTHESIS; HOST PATHOGEN INTERACTION; HUMAN; LENS IMPLANT; MINIMUM BACTERICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR PHYLOGENY; MOLECULAR TYPING; NEUROLOGICAL SURGICAL EQUIPMENT; NONHUMAN; PHENOTYPE; PROPIONIBACTERIUM ACNES; PROPIONIBACTERIUM ACNES INFECTION; PROSTHESIS INFECTION; REVIEW; RPOB GENE; TREATMENT PLANNING; BACTERIAL GENOME; BACTERIUM IDENTIFICATION; CEREBROSPINAL FLUID SHUNTING; CLASSIFICATION; COMMUNICABLE DISEASE; DRUG EFFECTS; ENDOPHTHALMITIS; EYE INFECTIONS, BACTERIAL; GENETICS; GRAM-POSITIVE BACTERIAL INFECTIONS; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE; PATHOGENICITY; PHYLOGENY; PHYSIOLOGY; PROCEDURES; PROSTHESIS-RELATED INFECTIONS; TRANSMISSION; VIRULENCE;

ACNE VULGARIS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; BIOFILMS; BREAST IMPLANTS; CEREBROSPINAL FLUID SHUNTS; COMMUNICABLE DISEASES, EMERGING; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENDOPHTHALMITIS; EYE INFECTIONS, BACTERIAL; GENOME, BACTERIAL; GRAM-POSITIVE BACTERIAL INFECTIONS; HOST-PATHOGEN INTERACTIONS; HUMANS; LENSES, INTRAOCULAR; MICROBIAL SENSITIVITY TESTS; PHYLOGENY; PROPIONIBACTERIUM ACNES; PROSTHESIS-RELATED INFECTIONS; VIRULENCE;

EID: 84902547686     PISSN: 0399077X     EISSN: 17696690     Source Type: Journal    
DOI: 10.1016/j.medmal.2014.02.004     Document Type: Review

References (59)

1. Douglas H.C., Gunter S.E. The taxonomic position of corynebacterium acnes. J Bacteriol 1946, 52:15-23.
2. Falentin H., Deutsch S.M., Jan G., Loux V., Thierry A., Parayre S., et al. The complete genome of Propionibacterium freudenreichii CIRM-BIA1, a hardy actinobacterium with food and probiotic applications. PLoS One 2010, 5(7):e11748.
3. Cohen R.J., Shannon B.A., McNeal J.E., Shannon T., Garrett K.L. Propionibacterium acnes associated with inflammation in radical prostatectomy specimens: a possible link to cancer evolution?. J Urol 2005, 173(6):1969-1974.
4. Colina M., Lo Monaco A., Khodeir M., Trotta F. Propionibacterium acnes and SAPHO syndrome: a case report and literature review. Clin Exp Rheumatol 2007, 25(3):457-460.
5. Ichikawa H., Kataoka M., Hiramatsu J., Ohmori M., Tanimoto Y., Kanehiro A., et al. Quantitative analysis of propionibacterial DNA in bronchoalveolar lavage cells from patients with sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 2008, 25(1):15-20.
6. Rieger U.M., Pierer G., Luscher N.J., Trampuz A. Sonication of removed breast implants for improved detection of subclinical infection. Aesthetic Plast Surg 2009, 33(3):404-408.
7. Conen A., Walti L.N., Merlo A., Fluckiger U., Battegay M., Trampuz A. Characteristics and treatment outcome of cerebrospinal fluid shunt-associated infections in adults: a retrospective analysis over an 11-year period. Clin Infect Dis 2008, 47(1):73-82.
8. Delahaye F., Fol S., Celard M., Vandenesch F., Beaune J., Bozio A., et al. Propionibacterium acnes infective endocarditis. Study of 11 cases and review of literature. Arch Mal Coeur Vaiss 2005, 98(12):1212-1218.
9. Deramo V.A., Ting T.D. Treatment of Propionibacterium acnes endophthalmitis. Curr Opin Ophthalmol 2001, 12(3):225-229.
10. Piper K.E., Jacobson M.J., Cofield R.H., Sperling J.W., Sanchez-Sotelo J., Osmon D.R., et al. Microbiologic diagnosis of prosthetic shoulder infection by use of implant sonication. J Clin Microbiol 2009, 47(6):1878-1884.
11. McDowell A., Perry A.L., Lambert P.A., Patrick S. A new phylogenetic group of Propionibacterium acnes. J Med Microbiol 2008, 57(Pt 2):218-224.
12. Sampedro M.F., Piper K.E., McDowell A., Patrick S., Mandrekar J.N., Rouse M.S., et al. Species of Propionibacterium and Propionibacterium acnes phylotypes associated with orthopedic implants. Diagn Microbiol Infect Dis 2009, 64(2):138-145.
13. Dumont-Wallon G., Moyse D., Blouin E., Dreno B. Bacterial resistance in French acne patients. Int J Dermatol 2010, 49:283-288.
14. Patel M., Bowe W.P., Heughebaert C., Shalita A.R. The development of antimicrobial resistance due to the antibiotic treatment of acne vulgaris: a review. J Drugs Dermatol 2010, 9:655-664.
15. Grice E.A., Segre J.A. The skin microbiome. Nat Rev Microbiol 2011, 9(4):244-253.
16. Csukas Z., Banizs B., Rozgonyi F. Studies on the cytotoxic effects of Propionibacterium acnes strains isolated from cornea. Microb Pathogen 2004, 36(3):171-174.
17. Webster G.F., Leyden J.J., Musson R.A., Douglas S.D. Susceptibility of Propionibacterium acnes to killing and degradation by human neutrophils and monocytes in vitro. Infect Immun 1985, 49(1):116-121.
18. Corvec S., Portillo M.E., Pasticci B.M., Borens O., Trampuz A. Epidemiology and new developments in the diagnosis of prosthetic joint infection. Int J Artif Organs 2012, 35(10):923-934.
19. Bruggemann H. Insights in the pathogenic potential of Propionibacterium acnes from its complete genome. Semin Cutan Med Surg 2005, 24(2):67-72.
20. Shaheen B., Gonzalez M. A microbial aetiology of acne: what is the evidence?. Br J Dermatol 2011, 165(3):474-485.
21. Kim J. Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses. Dermatology 2005, 211(3):193-198.
22. Beylot C., Auffret N., Poli F., Claudel J.P., Leccia M.T., Del Giudice P., et al. Propionibacterium acnes: an update on its role in the pathogenesis of acne. J Eur Acad Dermatol Venereol 2013.
23. Trampuz A., Piper K.E., Jacobson M.J., Hanssen A.D., Unni K.K., Osmon D.R., et al. Sonication of removed hip and knee prostheses for diagnosis of infection. N Engl J Med 2007, 357(7):654-663.
24. Furustrand Tafin U., Trampuz A., Corvec S. In vitro emergence of rifampicin resistance in Propionibacterium acnes and molecular characterization of mutations in the rpoB gene. J Antimicrob Chemother 2013, 68(3):523-528.
25. Portillo M.E., Salvado M., Sorli L., Alier A., Martínez S., Trampuz A., et al. Multiplex PCR of sonication fluid accurately differentiates between prosthetic joint infection and aseptic failure. J Infect 2012, 65(6):541-548.
26. Nelson C.L., McLaren A.C., McLaren S.G., Johnson J.W., Smeltzer M.S. Is aseptic loosening truly aseptic?. Clin Orthop Relat Res 2005, (437):25-30.
27. Zimmerli W., Trampuz A., Ochsner P.E. Prosthetic-joint infections. N Engl J Med 2004, 351(16):1645-1654.
28. Bémer P., Corvec S., Tariel S., Asseray N., Boutoille D., Langlois C., et al. Significance of Propionibacterium acnes-positive samples in spinal instrumentation. Spine 2008, 33(26):E971-E976.
29. Sampedro M.F., Huddleston P.M., Piper K.E., Karau M.J., Dekutoski M.B., Yaszemski M.J., et al. A biofilm approach to detect bacteria on removed spinal implants. Spine 2010, 35(12):1218-1224.
30. Crémet L., Corvec S., Bémer P., Bret L., Lebrun C., Lesimple B., et al. Orthopaedic-implant infections by Escherichia coli: molecular and phenotypic analysis of the causative strains. J infect 2012, 64(2):169-175.
31. Lalani T., Person A.K., Hedayati S.S., Moore L., Murdoch D.R., Hoen B., et al. Propionibacterium endocarditis: a case series from the International Collaboration on Endocarditis Merged Database and Prospective Cohort Study. Scand J Infect Dis 2007, 39(10):840-848.
32. Mayhall C.G., Archer N.H., Lamb V.A., Spadora A.C., Baggett J.W., Ward J.D., et al. Ventriculostomyrelated infections. A prospective epidemiologic study. N Engl J Med 1984, 310(9):553-559.
33. Walti L.N., Conen A., Coward J., Jost G.F., Trampuz A. Characteristics of infections associated with external ventricular drains of cerebrospinal fluid. J. Infect 2013, 66(5):424-431.
34. Pittet B., Montandon D., Pittet D. Infection in breast implants. Lancet Infect Dis 2005, 5(2):94-106.
35. Rieger U.M., Mesina J., Kalbermatten D.F., Haug M., Frey H.P., Pico R., et al. Bacterial biofilms and capsular contracture in patients with breast implants. Br J Surg 2013, 100(6):768-774.
36. Lohmann C.P., Linde H.J., Reischl U. Improved detection of microorganisms by polymerase chain reaction in delayed endophthalmitis after cataract surgery. Ophthalmology 2000, 107(6):1047-1051. [discussion 51-52].
37. Brüggemann H. Insights in the pathogenic potential of Propionibacterium acnes from its complete genome. Semin Cutan Med Surg 2005, 24:67-72.
38. Holland C., Mak T.N., Zimny-Arndt U., Schmid M., Meyer T.F., Jungblut P.R., et al. Proteomic identification of secreted proteins of Propionibacterium acnes. BMC Microbiol 2010, 10:230.
39. Lodes M.J., Secrist H., Benson D.R., Jen S., Shanebeck K.D., Guderian J., et al. Variable expression of immunoreactive surface proteins of Propionibacterium acnes. Microbiology 2006, 152:3667-3681.
40. McDowell A., Barnard E., Nagy I., Gao A., Tomida S., Li H., et al. An expanded multilocus sequence typing scheme for Propionibacterium acnes: investigation of "pathogenic" "commensal" and antibiotic resistant strains. PLoS One 2012, 7:e41480.
41. McDowell A., Nagy I., Magyari M., Barnard E., Patrick S. The opportunistic pathogen Propionibacterium acnes: insights into typing, human disease, clonal diversification and CAMP factor evolution. PLoS One 2013, 8:e70897.
42. Brzuszkiewicz E., Weiner J., Wollherr A., Thürmer A., Hüpeden J., Lomholt H.B., et al. Comparative genomics and transcriptomics of Propionibacterium acnes. PLoS One 2011, 6:e21581.
43. Fassi Fehri L., Mak T.N., Laube B., Brinkmann V., Ogilvie L.A., Mollenkopf H., et al. Prevalence of Propionibacterium acnes in diseased prostates and its inflammatory and transforming activity on prostate epithelial cells. Int J Med Microbiol 2011, 301:69-78.
44. Furukawa A., Uchida K., Ishige Y., Ishige I., Kobayashi I., Takemura T., et al. Characterization of Propionibacterium acnes isolates from sarcoid and non-sarcoid tissues with special reference to cell-invasiveness, serotype, and trigger factor gene polymorphism. Microb Pathogen 2009, 46:80-87.
45. Oprica C., Emtestam L., Lapins J., Borglund E., Nyberg F., Stenlund K., et al. Antibiotic-resistant Propionibacterium acnes on the skin of patients with moderate to severe acne in Stockholm. Anaerobe 2004, 10:155-164.
46. Oprica C., Nord C.E. European surveillance study on the antibiotic susceptibility of Propionibacterium acnes. Clin Microbiol Infect 2005, 11:204-213. ESCMID Study Group on Antimicrobial Resistance in Anaerobic Bacteria.
47. Unemo M., Friberg O., Enquist E., Källman J., Söderquist B. Genetic homogeneity/heterogeneity of Propionibacterium acnes isolated from patients during cardiothoracic reoperation. Anaerobe 2007, 13(3-4):121-126.
48. Kilian M., Scholz C.F., Lomholt H.B. Multilocus sequence typing and phylogenetic analysis of Propionibacterium acnes. J Clin Microbiol 2012, 50(4):1158-1165.
49. Davidsson S., Söderquist B., Elgh F., Olsson J., Andrén O., Unemo M., et al. Multilocus sequence typing and repetitive-sequence-based PCR (DiversiLab) for molecular epidemiological characterization of Propionibacterium acnes isolates of heterogeneous origin. Anaerobe 2012, 18(4):392-399.
50. Denys G.A., Jerris R.C., Swenson J.M., Thornsberry C. Susceptibility of Propionibacterium acnes clinical isolates to 22 antimicrobial agents. Antimicrob Agents Chemother 1983, 23:335-337.
51. Furustrand Tafin U., Corvec S., Betrisey B., Zimmerli W., Trampuz A. Role of rifampin against Propionibacterium acnes biofilm in vitro and in an experimental foreign-body infection model. Antimicrob Agents Chemother 2012, 56:1885-1891.
52. Nord C.E., Oprica C. Antibiotic resistance in Propionibacterium acnes. Microbiological and clinical aspects. Anaerobe 2006, 12:207-210.
53. Ross J.I., Eady E.A., Cove J.H., Jones C.E., Ratyal A.H., Miller Y.W., et al. Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA. Antimicrob Agents Chemother 1997, 41:1162-1165.
54. Ross J.I., Snelling A.M., Carnegie E., Coates P., Cunliffe W.J., Bettoli V., et al. Antibiotic-resistant acne: lessons from Europe. Br J Dermatol 2003, 148:467-478.
55. Eady E.A., Gloor M., Leyden J.J. Propionibacterium acnes resistance: a worldwide problem. Dermatology 2003, 206:54-56.
56. Ross J.I., Eady E.A., Carnegie E., Cove J.H. Detection of transposon Tn5432-mediated macrolide-lincosamide-streptogramin B (MLSB) resistance in cutaneous propionibacteria from six European cities. J Antimicrob Chemother 2002, 49:165-168.
57. Zappe B., Graf S., Ochsner P.E., Zimmerli W., Sendi P. Propionibacterium spp. in prosthetic joint infections: a diagnostic challenge. Arch Orthop Trauma Surg 2008, 128:1039-1046.
58. Holmberg A., Lood R., Morgelin M., Soderquist B., Holst E., Collin M., et al. Biofilm formation by Propionibacterium acnes is a characteristic of invasive isolates. Clin Microbiol Infect 2009, 15:787-795.
59. Osmon D.R., Berbari E.F., Berendt A.R., Lew D., Zimmerli W., Steckelberg J.M., et al. Executive summary: diagnosis and management of prosthetic joint infection: clinical practice guidelines by the infectious diseases society of america. Clin Infect Dis 2013, 56:1-10.