Anti-hypertrophic effects of oxytocin in rat ventricular myocytes

International Journal of Cardiology

Volumn 175, Issue 1, 2014, Pages 38-49

  Menaouar, Ahmed ^a   Florian, Maria ^a   Wang, Donghao ^a   Danalache, Bogdan ^a   Jankowski, Marek ^a   Gutkowska, Jolanta ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Atrial natriuretic peptide; Cardiac myocytes; Cyclic GMP; Endothelin 1; Hypertrophy; Oxytocin

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CYCLIC GMP; ENDOTHELIN 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYTOCIN; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTROPIC ACTIVITY; ARTICLE; CARDIOVASCULAR RESPONSE; CELL GROWTH; CELL NUCLEUS; CELL SIZE; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; GROWTH INHIBITION; HEART HYPERTROPHY; HEART MUSCLE CELL; MALE; MOUSE; NEWBORN; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; ANIMAL; CARDIOMEGALY; CELL CULTURE; CELL DIFFERENTIATION; CELL ENLARGEMENT; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; ANIMALS, NEWBORN; CARDIOMEGALY; CELL DIFFERENTIATION; CELL ENLARGEMENT; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MYOCYTES, CARDIAC; OXYTOCIN; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME;

EID: 84902546203     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.04.174     Document Type: Article

References (46)

1. G. Gimpl, and F. Fahrenholz The oxytocin receptor system: structure, function, and regulation Physiol Rev 81 2001 629 683
2. M. Jankowski, F. Hajjar, and S.A. Kawas et al. Rat heart: a site of oxytocin production and action Proc Natl Acad Sci U S A 95 1998 14558 14563
3. M. Petersson Cardiovascular effects of oxytocin Prog Brain Res 139 2002 281 288
4. M. Jankowski, V. Bissonauth, and L. Gao et al. Anti-inflammatory effect of oxytocin in rat myocardial infarction Basic Res Cardiol 105 2010 205 218
5. J. Gutkowska, and M. Jankowski Oxytocin revisited: its role in cardiovascular regulation J Neuroendocrinol 24 2012 599 608
6. C.Y. Ku, A. Qian, Y. Wen, K. Anwer, and B.M. Sanborn Oxytocin stimulates myometrial guanosine triphosphatase and phospholipase-C activities via coupling to G alpha q/11 Endocrinology 136 1995 1509 1515
7. J.N. Pont, C.A. McArdle, and Bernal A. Lopez Oxytocin-stimulated NFAT transcriptional activation in human myometrial cells Mol Endocrinol 26 2012 1743 1756
8. I. Kehat, and J.D. Molkentin Molecular pathways underlying cardiac remodeling during pathophysiological stimulation Circulation 122 2010 2727 2735
9. J.D. Molkentin Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs Cardiovasc Res 63 2004 467 475
10. B.A. Danalache, J. Gutkowska, M.J. Slusarz, I. Berezowska, and M. Jankowski Oxytocin-Gly-Lys-Arg: a novel cardiomyogenic peptide PLoS ONE 5 2010 e13643
11. N. Gassanov, D. Devost, and B. Danalache et al. Functional activity of the carboxyl-terminally extended oxytocin precursor peptide during cardiac differentiation of embryonic stem cells Stem Cells 26 2008 45 54
12. M. Florian, M. Jankowski, and J. Gutkowska Oxytocin increases glucose uptake in neonatal rat cardiomyocytes Endocrinology 151 2010 482 491
13. P. Cassoni, T. Marrocco, and B. Bussolati et al. Oxytocin induces proliferation and migration in immortalized human dermal microvascular endothelial cells and human breast tumor-derived endothelial cells Mol Cancer Res 4 2006 351 359
14. J. Paquin, B.A. Danalache, M. Jankowski, S.M. McCann, and J. Gutkowska Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes Proc Natl Acad Sci U S A 99 2002 9550 9555
15. L. Hatami, M.R. Valojerdi, and S.J. Mowla Effects of oxytocin on cardiomyocyte differentiation from mouse embryonic stem cells Int J Cardiol 117 2007 80 89
16. N. Noiseux, M. Borie, and A. Desnoyers et al. Preconditioning of stem cells by oxytocin to improve their therapeutic potential Endocrinology 153 2012 5361 5372
17. M.E. Krahl Specificity of insulin or oxytocin stimulation of protein synthesis in adipose tissue Am J Physiol 207 1964 1169 1172
18. D. Devost, M. Girotti, M.E. Carrier, C. Russo, and H.H. Zingg Oxytocin induces dephosphorylation of eukaryotic elongation factor 2 in human myometrial cells Endocrinology 146 2005 2265 2270
19. I. Shiojima, M. Yefremashvili, and Z. Luo et al. Akt signaling mediates postnatal heart growth in response to insulin and nutritional status J Biol Chem 277 2002 37670 37677
20. A. Tardif, N. Julien, and A. Pelletier et al. Chronic exposure to beta-hydroxybutyrate impairs insulin action in primary cultures of adult cardiomyocytes Am J Physiol Endocrinol Metab 281 2001 E1205 E1212
21. D. Devost, M.E. Carrier, and H.H. Zingg Oxytocin-induced activation of eukaryotic elongation factor 2 in myometrial cells is mediated by protein kinase C Endocrinology 149 2008 131 138
22. J. Gutkowska Radioimmunoassay for atrial natriuretic factor Int J Radiat Appl Instrum B Nucl Med Biol 14 1987 323 331
23. J. Gutkowska, M. Jankowski, C. Lambert, S. Mukaddam-Daher, H.H. Zingg, and S.M. McCann Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart Proc Natl Acad Sci U S A 94 1997 11704 11709
24. J. Gutkowska, S. Mukaddam-Daher, and J. Tremblay The peripheral action of clonidine analog ST-91: involvement of atrial natriuretic factor J Pharmacol Exp Ther 281 1997 670 676
25. N. Frey, H.A. Katus, E.N. Olson, and J.A. Hill Hypertrophy of the heart: a new therapeutic target? Circulation 109 2004 1580 1589
26. H. Link, G. Dayanithi, K.J. Fohr, and M. Gratzl Oxytocin at physiological concentrations evokes adrenocorticotropin (ACTH) release from corticotrophs by increasing intracellular free calcium mobilized mainly from intracellular stores. Oxytocin displays synergistic or additive effects on ACTH-releasing factor or arginine vasopressin-induced ACTH secretion, respectively Endocrinology 130 1992 2183 2191
27. T. Horio, T. Nishikimi, F. Yoshihara, H. Matsuo, S. Takishita, and K. Kangawa Inhibitory regulation of hypertrophy by endogenous atrial natriuretic peptide in cultured cardiac myocytes Hypertension 35 2000 19 24
28. A.M. Alizadeh, M. Faghihi, and H.R. Sadeghipour et al. Oxytocin protects rat heart against ischemia-reperfusion injury via pathway involving mitochondrial ATP-dependent potassium channel Peptides 31 2010 1341 1345
29. H. Kobayashi, S. Yasuda, and N. Bao et al. Postinfarct treatment with oxytocin improves cardiac function and remodeling via activating cell-survival signals and angiogenesis J Cardiovasc Pharmacol 54 2009 510 519
30. M. Ondrejcakova, T. Ravingerova, J. Bakos, D. Pancza, and D. Jezova Oxytocin exerts protective effects on in vitro myocardial injury induced by ischemia and reperfusion Can J Physiol Pharmacol 87 2009 137 142
31. J.R. Dietz Mechanisms of atrial natriuretic peptide secretion from the atrium Cardiovasc Res 68 2005 8 17
32. M. Toth, K.H. Vuorinen, and O. Vuolteenaho et al. Hypoxia stimulates release of ANP and BNP from perfused rat ventricular myocardium Am J Physiol 266 1994 H1572 H1580
33. S.M. McCann, J. Antunes-Rodrigues, M. Jankowski, and J. Gutkowska Oxytocin, vasopressin and atrial natriuretic peptide control body fluid homeostasis by action on their receptors in brain, cardiovascular system and kidney Prog Brain Res 139 2002 309 328
34. P.M. Oliver, J.E. Fox, and R. Kim et al. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A Proc Natl Acad Sci U S A 94 1997 14730 14735
35. A. Calderone, C.M. Thaik, N. Takahashi, D.L. Chang, and W.S. Colucci Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts J Clin Invest 101 1998 812 818
36. J.C. Hunter, A. Zeidan, S. Javadov, A. Kilic, V. Rajapurohitam, and M. Karmazyn Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway J Mol Cell Cardiol 47 2009 810 818
37. B. Fiedler, S.M. Lohmann, and A. Smolenski et al. Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes Proc Natl Acad Sci U S A 99 2002 11363 11368
38. B.J. Wilkins, Y.S. Dai, and O.F. Bueno et al. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy Circ Res 94 2004 110 118
39. J. Heineke, and J.D. Molkentin Regulation of cardiac hypertrophy by intracellular signalling pathways Nat Rev Mol Cell Biol 7 2006 589 600
40. M. Ondrejcakova, M. Barancik, M. Bartekova, T. Ravingerova, and D. Jezova Prolonged oxytocin treatment in rats affects intracellular signaling and induces myocardial protection against infarction Gen Physiol Biophys 31 2012 261 270
41. O.J. Kemi, M. Ceci, and U. Wisloff et al. Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy J Cell Physiol 214 2008 316 321
42. D. Devost, P. Wrzal, and H.H. Zingg Oxytocin receptor signalling Prog Brain Res 170 2008 167 176
43. B.Y. Klein, H. Tamir, D.L. Hirschberg, S.B. Glickstein, and M.G. Welch Oxytocin modulates mTORC1 pathway in the gut Biochem Biophys Res Commun 432 2013 466 471
44. Y. Wang, E. Gao, and L. Tao et al. AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin Circulation 119 2009 835 844
45. D.G. Hardie, and D. Carling The AMP-activated protein kinase - fuel gauge of the mammalian cell? Eur J Biochem/FEBS 246 1997 259 273
46. J.R. Dyck, and G.D. Lopaschuk AMPK alterations in cardiac physiology and pathology: enemy or ally? J Physiol 574 2006 95 112