Adverse childhood experiences are associated with detrimental hemodynamics and elevated circulating endothelin-1 in adolescents and young adults

Hypertension

Volumn 64, Issue 1, 2014, Pages 201-207

  Su, Shaoyong ^a   Wang, Xiaoling ^a   Kapuku, Gaston K ^a   Treiber, Frank A ^c   Pollock, David M ^b,d   Harshfield, Gregory A ^a   McCall, W Vaughn ^b   Pollock, Jennifer S ^b,d  

^a AUGUSTA UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d Cardio Renal Physiology and Medicine Division of Nephrology Department of Medicine   (United States)

Author keywords

adverse childhood experiences; blood pressure; endothelin 1; pulse wave analysis; vascular resistance

Indexed keywords

ENDOTHELIN 1;

ADOLESCENT; ADULT; ARTERIAL STIFFNESS; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR RISK; CHILD ABUSE; DIASTOLIC BLOOD PRESSURE; EARLY LIFE STRESS; FEMALE; HEMODYNAMICS; HUMAN; MALE; NEGLECT; PRIORITY JOURNAL; PULSE WAVE; VASCULAR RESISTANCE; YOUNG ADULT;

ADVERSE CHILDHOOD EXPERIENCES; BLOOD PRESSURE; ENDOTHELIN-1; PULSE WAVE ANALYSIS; VASCULAR RESISTANCE;

ADOLESCENT; ADULT; ENDOTHELIN-1; FEMALE; HEMODYNAMICS; HUMANS; LIFE CHANGE EVENTS; MALE; STRESS, PSYCHOLOGICAL;

EID: 84902545589     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.02755     Document Type: Article

References (46)

1. Gilbert R, Widom CS, Browne K, Fergusson D, Webb E, Janson S. Burden and consequences of child maltreatment in high-income countries. Lancet. 2009;373: 68-81.
2. McLaughlin KA, Green JG, Gruber MJ, Sampson NA, Zaslavsky AM, Kessler RC. Childhood adversities and adult psychopathology in the National Comorbidity Survey Replication (NCS-R) III: associations with functional impairment related to DSM-IV disorders. Psychol Med. 2010;40: 847-859.
3. Miller GE, Chen E, Parker KJ. Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms. Psychol Bull. 2011; 137: 959-997.
4. Anda RF, Dong M, Brown DW, Felitti VJ, Giles WH, Perry GS, Valerie EJ, Dube SR. The relationship of adverse childhood experiences to a history of premature death of family members. BMC Public Health. 2009;9:106.
5. Dong M, Giles WH, Felitti VJ, Dube SR, Williams JE, Chapman DP, Anda RF. Insights into causal pathways for ischemic heart disease: adverse childhood experiences study. Circulation. 2004;110: 1761-1766.
6. Dube SR, Fairweather D, Pearson WS, Felitti VJ, Anda RF, Croft JB. Cumulative childhood stress and autoimmune diseases in adults. Psychosom Med. 2009;71: 243-250.
7. Rich-Edwards JW, Spiegelman D, Lividoti Hibert EN, Jun HJ, Todd TJ, Kawachi I, Wright RJ. Abuse in childhood and adolescence as a predictor of type 2 diabetes in adult women. Am J Prev Med. 2010;39: 529-536.
8. Riley EH, Wright RJ, Jun HJ, Hibert EN, Rich-Edwards JW. Hypertension in adult survivors of child abuse: observations from the Nurses' Health Study II. J Epidemiol Community Health. 2010;64: 413-418.
9. Alastalo H, Raikkonen K, Pesonen AK, Osmond C, Barker DJ, Kajantie E, Heinonen K, Forsen TJ, Eriksson JG. Cardiovascular health of Finnish war evacuees 60 years later. Ann Med. 2009;41: 66-72.
10. Wegman HL, Stetler C. A meta-analytic review of the effects of childhood abuse on medical outcomes in adulthood. Psychosom Med. 2009;71: 805-812.
11. Vig R, Gordon JR, Thébaud B, Befus AD, Vliagoftis H. The effect of early- life stress on airway inflammation in adult mice. Neuroimmunomodulation. 2010;17: 229-239.
12. Biagini G, Pich EM, Carani C, Marrama P, Agnati LF. Postnatal maternal separation during the stress hyporesponsive period enhances the adrenocortical response to novelty in adult rats by affecting feedback regulation in the CA1 hippocampal field. Int J Dev Neurosci. 1998;16: 187-197.
13. Hilakivi-Clarke LA, Turkka J, Lister RG, Linnoila M. Effects of early postnatal handling on brain beta-adrenoceptors and behavior in tests related to stress. Brain Res. 1991;542: 286-292.
14. Loria AS, D'Angelo G, Pollock DM, Pollock JS. Early life stress downregulates endothelin receptor expression and enhances acute stress- mediated blood pressure responses in adult rats. Am J Physiol Regul Integr Comp Physiol. 2010;299:R185-R191.
15. Khimji AK, Rockey DC. Endothelin-biology and disease. Cell Signal. 2010;22: 1615-1625.
16. Vuurmans TJ, Boer P, Koomans HA. Effects of endothelin-1 and endothelin- 1 receptor blockade on cardiac output, aortic pressure, and pulse wave velocity in humans. Hypertension. 2003;41: 1253-1258.
17. Wang X, Poole JC, Treiber FA, Harshfield GA, Hanevold CD, Snieder H. Ethnic and gender differences in ambulatory blood pressure trajectories: results from a 15-year longitudinal study in youth and young adults. Circulation. 2006;114: 2780-2787.
18. Kapuku GK, Treiber FA, Davis HC, Harshfield GA, Cook BB, Mensah GA. Hemodynamic function at rest, during acute stress, and in the field: predictors of cardiac structure and function 2 years later in youth. Hypertension. 1999;34: 1026-1031.
19. Ge D, Young TW, Wang X, Kapuku GK, Treiber FA, Snieder H. Heritability of arterial stiffness in black and white American youth and young adults. Am J Hypertens. 2007;20: 1065-1072.
20. Hollingshead A. Four Factor Index of Social Status. New Haven, CT: Department of Sociology; 1981.
21. Sobel ME. Asymptotic confidence intervals for indirect effects in structural equation models. In: Leinhardt S, ed. Sociological Methodology. Washington, DC: American Sociological Association; 1982.
22. Fagard RH, Pardaens K, Staessen JA, Thijs L. Prognostic value of invasive hemodynamic measurements at rest and during exercise in hypertensive men. Hypertension. 1996;28: 31-36.
23. Kaess BM, Rong J, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Aortic stiffness, blood pressure progression, and incident hypertension. JAMA. 2012;308: 875-881.
24. Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, Asmar R, Reneman RS, Hoeks AP, Breteler MM, Witteman JC. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation. 2006;113: 657-663.
25. Sutton-Tyrrell K, Najjar SS, Boudreau RM, Venkitachalam L, Kupelian V, Simonsick EM, Havlik R, Lakatta EG, Spurgeon H, Kritchevsky S, Pahor M, Bauer D, Newman A; Health ABC Study. Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation. 2005;111: 3384-3390.
26. Meaume S, Benetos A, Henry OF, Rudnichi A, Safar ME. Aortic pulse wave velocity predicts cardiovascular mortality in subjects >70 years of age. Arterioscler Thromb Vasc Biol. 2001;21: 2046-2050.
27. Weisbrod RM, Shiang T, Al Sayah L, Fry JL, Bajpai S, Reinhart-King CA, Lob HE, Santhanam L, Mitchell G, Cohen RA, Seta F. Arterial stiffening precedes systolic hypertension in diet-induced obesity. Hypertension. 2013;62: 1105-1110.
28. Pesonen AK, Räikkönen K, Feldt K, Heinonen K, Osmond C, Phillips DI, Barker DJ, Eriksson JG, Kajantie E. Childhood separation experience predicts HPA axis hormonal responses in late adulthood: a natural experiment of World War II. Psychoneuroendocrinology. 2010;35: 758-767.
29. Cicchetti D, Rogosch FA. Diverse patterns of neuroendocrine activity in maltreated children. Dev Psychopathol. 2001;13: 677-693.
30. Danese A, Moffitt TE, Harrington H, Milne BJ, Polanczyk G, Pariante CM, Poulton R, Caspi A. Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers. Arch Pediatr Adolesc Med. 2009;163: 1135-1143.
31. Danese A, Moffitt TE, Pariante CM, Ambler A, Poulton R, Caspi A. Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Arch Gen Psychiatry. 2008;65: 409-415.
32. Danese A, Pariante CM, Caspi A, Taylor A, Poulton R. Childhood maltreatment predicts adult inflammation in a life-course study. Proc Natl Acad Sci U S A. 2007;104: 1319-1324.
33. Lippmann M, Bress A, Nemeroff CB, Plotsky PM, Monteggia LM. Long- term behavioural and molecular alterations associated with maternal separation in rats. Eur J Neurosci. 2007;25: 3091-3098.
34. Loria AS, Pollock DM, Pollock JS. Early life stress sensitizes rats to angiotensin II-induced hypertension and vascular inflammation in adult life. Hypertension. 2010;55: 494-499.
35. Rodríguez-Pascual F, Busnadiego O, Lagares D, Lamas S. Role of endothelin in the cardiovascular system. Pharmacol Res. 2011;63: 463-472.
36. MacCarthy PA, Grocott-Mason R, Prendergast BD, Shah AM. Contrasting inotropic effects of endogenous endothelin in the normal and failing human heart: studies with an intracoronary ET(A) receptor antagonist. Circulation. 2000;101: 142-147.
37. Browatzki M, Schmidt J, Kübler W, Kranzhöfer R. Endothelin-1 induces interleukin-6 release via activation of the transcription factor NF-kappaB in human vascular smooth muscle cells. Basic Res Cardiol. 2000;95: 98-105.
38. Malendowicz LK, Nussdorfer GG, Meneghelli V, Nowak M, Markowska A, Majchrzak M. Effects of endothelin-1 on the rat pituitary-adrenocortical axis under basal and stressful conditions. Endocr Res. 1997;23: 349-364.
39. Dhaun N, MacIntyre IM, Kerr D, Melville V, Johnston NR, Haughie S, Goddard J, Webb DJ. Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease. Hypertension. 2011;57: 772-779.
40. Treiber FA, Kapuku GK, Davis H, Pollock JS, Pollock DM. Plasma endothelin- 1 release during acute stress: role of ethnicity and sex. Psychosom Med. 2002;64: 707-713.
41. Evans RR, Phillips BG, Singh G, Bauman J L, Gulati A. Racial and gender differences in endothelin-1. Am J Cardiol. 1996;78: 486-488.
42. Polderman KH, Stehouwer CD, van Kamp GJ, Dekker GA, Verheugt FW, Gooren LJ. Influence of sex hormones on plasma endothelin levels. Ann Intern Med. 1993;118: 429-432.
43. Morris AA, Patel RS, Binongo JN, Poole J, Mheid IA, Ahmed Y, Stoyanova N, Vaccarino V, Din-Dzietham R, Gibbons GH, Quyyumi A. Racial differences in arterial stiffness and microcirculatory function between Black and White Americans. J Am Heart Assoc. 2013;2:e002154.
44. Snieder H, Harshfield GA, Treiber FA. Heritability of blood pressure and hemodynamics in African- and European-American youth. Hypertension. 2003;41: 1196-1201.
45. Bentley T, Widom CS. A 30-year follow-up of the effects of child abuse and neglect on obesity in adulthood. Obesity (Silver Spring). 2009;17: 1900-1905.
46. Galobardes B, Lynch JW, Smith GD. Is the association between childhood socioeconomic circumstances and cause-specific mortality established? Update of a systematic review. J Epidemiol Community Health. 2008;62: 387-390.