A randomized, open-label clinical trial of tasisulam sodium versus paclitaxel as second-line treatment in patients with metastatic melanoma

Cancer

Volumn 120, Issue 13, 2014, Pages 2016-2024

  Hamid, Omid ^a   Ilaria, Robert ^b   Garbe, Claus ^c   Wolter, Pascal ^d   Maio, Michele ^e   Hutson, Thomas E ^f   Arance, Ana ^g   Lorigan, Paul ^h   Lee, Jeeyun ⁱ   Hauschild, Axel ^j   Mohr, Peter ^k   Hahka Kemppinen, Marjo ^b   Kaiser, Christopher ^b   Turner, P Kellie ^b   Conti, Ilaria ^b   Grob, Jean Jacques ^l  

^a Angeles Clinic and Research Institute   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e UNIVERSITY HOSPITAL OF SIENA   (Italy)

^f BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^g HOSPITAL CLÍNIC   (Spain)

^h UNIVERSITY OF MANCHESTER   (United Kingdom)

ⁱ Samsung Medical Center   (South Korea)

^j UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^k Elbe Kliniken   (Germany)

^l AIX MARSEILLE UNIVERSITY   (France)

more..

Author keywords

clinical trial; LY573636; melanoma; paclitaxel; phase 3 chemotherapy; tasisulam

Indexed keywords

PACLITAXEL; TASISULAM;

ADULT; AGED; ALOPECIA; AREA UNDER THE CURVE; ARTICLE; BONE MARROW SUPPRESSION; CONTROLLED STUDY; DIARRHEA; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG FATALITY; DRUG SAFETY; DRUG WITHDRAWAL; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; HEART DISEASE; HUMAN; INFECTION; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; METASTATIC MELANOMA; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; OPEN STUDY; OVERALL SURVIVAL; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL; SENSORY NEUROPATHY; THROMBOCYTOPENIA;

CLINICAL TRIAL; LY573636; MELANOMA; PACLITAXEL; PHASE 3 CHEMOTHERAPY; TASISULAM;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BENZAMIDES; CHEMOTHERAPY-INDUCED FEBRILE NEUTROPENIA; DISEASE-FREE SURVIVAL; DRUG ADMINISTRATION SCHEDULE; EARLY TERMINATION OF CLINICAL TRIALS; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; LEUKOPENIA; MALE; MELANOMA; MIDDLE AGED; NEOPLASM STAGING; PACLITAXEL; SEVERITY OF ILLNESS INDEX; SKIN NEOPLASMS; SULFONAMIDES; THROMBOCYTOPENIA; TREATMENT OUTCOME;

EID: 84902535288     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.28635     Document Type: Article

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