Interrelation between genotypes of the vitamin D receptor gene and serum sex hormone concentrations in the Polish elderly population: The PolSenior study

Experimental Gerontology

Volumn 57, Issue , 2014, Pages 188-190

  Laczmanski, Lukasz ^a   Milewicz, Andrzej ^a   Puzianowska Kuznicka, Monika ^b,c   Lwow, Felicja ^d   Kolackov, Katarzyna ^a   Mieszczanowicz, Urszula ^a   Pawlak, Maurycy ^a   Krzyzanowska Swiniarska, Barbara ^e   Bar Andziak, Ewa ^f   Chudek, Jerzy ^g   Mossakowska, Malgorzata ^h  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

^d UNIVERSITY SCHOOL OF PHYSICAL EDUCATION   (Poland)

^e POMERANIAN MEDICAL UNIVERSITY   (Poland)

^f MEDICAL UNIVERSITY OF WARSAW   (Poland)

^g MEDICAL UNIVERSITY OF SILESIA   (Poland)

^h INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

Author keywords

Elderly; Estrogen; Polymorphism; Testosterone; Vitamin D receptor (VDR)

Indexed keywords

ESTRADIOL; SEX HORMONE; TESTOSTERONE; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR;

AGE DISTRIBUTION; AGED; ANALYTICAL PARAMETERS; ARTICLE; DNA POLYMORPHISM; ESTRADIOL BLOOD LEVEL; ETHNIC GROUP; FEMALE; FREE ANDROGEN INDEX; FREE ESTROGEN INDEX; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC LINKAGE; GENOTYPE; HETEROZYGOTE; HORMONAL REGULATION; HORMONE SYNTHESIS; HUMAN; MALE; POLISH; PREVALENCE; PRIORITY JOURNAL; SEX DIFFERENCE; TESTOSTERONE BLOOD LEVEL; VERY ELDERLY; VITAMIN D RECEPTOR GENE; BLOOD; COHORT ANALYSIS; GENETICS; POLAND;

AGED; AGED, 80 AND OVER; COHORT STUDIES; ESTRADIOL; FEMALE; GENOTYPE; HUMANS; MALE; POLAND; RECEPTORS, CALCITRIOL; TESTOSTERONE;

EID: 84902518839     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2014.06.007     Document Type: Article

References (23)

1. Barrera D., Avila E., Hernández G., Halhali A., Biruete B., Larrea F., Díaz L. Estradiol and progesterone synthesis in human placenta is stimulated by calcitriol. J. Steroid Biochem. Mol. Biol. 2007, 103:529-532.
2. Binh Tran Quang, Nakahori Yutaka, Hien Vi Thi Thu, Khan Nguyen Cong, Lam Nguyen Thi, Mai le Bach, Yamamoto Shigeru Correlations between genetic variance and adiposity measures, and gene×gene interactions for obesity in postmenopausal Vietnamese women. J. Genet. 2011, 90:1-9.
3. Bledowski P., Mossakowska M., Chudek J., Grodzicki T., Milewicz A., Szybalska A., Wieczorowska-tobis K., Wiecek A., Bartoszek A., Dabrowski A., Zdrojewski T. Medical, psychological and socioeconomic aspects of aging in Poland: assumptions and objectives of the PolSenior project. Exp. Gerontol. 2011, 46:1003-1009.
4. Burger Henry G. Androgen production in women. Fertil. Steril. 2002, 77(Suppl. 4):S3-S5.
5. Cheng S., Massaro J.M., Fox C.S., Larson M.G., Keyes M.J., Mccabe E.L., Robins S.J., O'donnell C.J., Hoffmann U., Jacques P.F., Booth S.L., Vasan R.S., Wolf M., Wang T.J. Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study. Diabetes 2010, 59:242-248.
6. Freedman D.M., Looker A.C., Chang S.C., Graubard B.I. Prospective study of serum vitamin D and cancer mortality in the United States. J. Natl. Cancer Inst. 2007, 99:1594-1602.
7. Holick M.F. Vitamin D deficiency. N. Engl. J. Med. 2007, 357:266-281.
8. Hsu J.W., Yasmin-Karim S., King M.R., Wojciechowski J.C., Mickelsen D., Blair M.L., Ting H.J., Ma W.L., Lee Y.F. Suppression of prostate cancer cell rolling and adhesion to endothelium by 1alpha,25-dihydroxyvitamin D3. Am. J. Pathol. 2011, 178:872-880.
9. Jiang M., Ma Y., Chen C., Fu X., Yang S., Li X., Yu G., Mao Y., Xie Y., Li Y. Androgen-responsive gene database: integrated knowledge on androgen-responsive genes. Mol. Endocrinol. 2009, 23:1927-1933.
10. Kizildag S., Ates H. Treatment of K562 cells with 1,25-dihydroxyvitamin D(3) induces distinct alterations in the expression of apoptosis-related genes BCL2, BAX, BCL(XL), and p21. Ann. Hematol. 2010, 89:1-7.
11. Krishnan A.V., Peehl D.M., Feldman D. Inhibition of prostate cancer growth by vitamin D: regulation of target gene expression. J. Cell. Biochem. 2003, 88:363-371.
12. Laczmanska I., Pesz K., Laczmanski L. Application of selected methods based on the polymerase chain reaction in medical molecular diagnostics. Adv. Clin. Exp. Med. 2009, 18:85-92.
13. Lerchbaum E., Obermayer-Pietsch B. Vitamin D and fertility: a systematic review. Eur. J. Endocrinol. 2012, 166:765-778.
14. Lins T.C.L., Nogueira L.R., Lima R.M., Gentil P., Oliveira R.J., Pereira R.W. A multiplex single-base extension protocol for genotyping Cdx2, FokI, BsmI, ApaI, and TaqI polymorphisms of the vitamin D receptor gene. Genet. Mol. Res. 2007, 6:316-324.
15. Mctiernan Anne, Rajan Kumar B., Tworoger Shelley S., Irwin Melinda, Bernstein Leslie, Baumgartner Richard, Gilliland Frank, Stanczyk Frank Z., Yasui Yutaka, Ballard-Barbash Rachel Adiposity and sex hormones in postmenopausal breast cancer survivors. J. Clin. Oncol. 2003, 21:1961-1966.
16. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl. Acids Res. 1988, 16:1215.
17. Norman A.W. From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health. Am. J. Clin. Nutr. 2008, 88:491S-499S.
18. Pilz S., Tomaschitz A., März W., Drechsler C., Ritz E., Zittermann A., Cavalier E., Pieber T.R., Lappe J.M., Grant W.B., Holick M.F., Dekker J.M. Vitamin D, cardiovascular disease and mortality. Clin. Endocrinol. 2011, 75:575-584.
19. Pittas A.G., Lau J., Hu F.B., Dawson-Hughes B. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J. Clin. Endocrinol. Metab. 2007, 92:2017-2029.
20. Protiva Petr, Cross Heide S., Hopkins Michael E., Kállay Enikö, Bises Giovanna, Dreyhaupt Eleanor, Augenlicht Leonard, Lipkin Martin, Lesser Martin, Livote Elayne, Holt Peter R. Chemoprevention of colorectal neoplasia by estrogen: potential role of vitamin D activity. Cancer Prev. Res. 2009, 2:43-51.
21. Tang S., Han H., Bajic V.B. ERGDB: estrogen responsive genes database. Nucleic Acids Res. 2004, 32:533-536.
22. Uitterlinden A.G., Fang Y., Van Meurs J.B., Pols H.A., Van Leeuwen J.P. Genetics and biology of vitamin D receptor polymorphisms. Gene 2004, 338:143-156.
23. Wehr E., Pieber T.R., Obermayer-Pietsch B. Effect of vitamin D3 treatment on glucose metabolism and menstrual frequency in polycystic ovary syndrome women: a pilot study. J. Endocrinol. Investig. 2011, 34:757-763.