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Volumn 4, Issue 8, 2014, Pages 770-777

64Cu labeled sarcophagine exendin-4 for microPET imaging of glucagon like peptide-1 receptor expression

Author keywords

Exendin 4 dimer; Insulinoma; PET; Sarcophagine

Indexed keywords

COPPER 64; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; RADIOPHARMACEUTICAL AGENT; ALANYLTYROSINE; COPPER; DIPEPTIDE; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; PEPTIDE; VENOM;

EID: 84902494209     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.7759     Document Type: Article
Times cited : (40)

References (39)
  • 1
    • 14844329847 scopus 로고    scopus 로고
    • Imaging and localization of islet-cell tumours of the pancreas on CT and MRI. Best Pract
    • Noone TC, Hosey J, Firat Z, Semelka RC. Imaging and localization of islet-cell tumours of the pancreas on CT and MRI. Best Pract. Res Clin Endocrinol Metab. 2005; 19: 195-211.
    • (2005) Res Clin Endocrinol Metab , vol.19 , pp. 195-211
    • Noone, T.C.1    Hosey, J.2    Firat, Z.3    Semelka, R.C.4
  • 2
    • 0033956609 scopus 로고    scopus 로고
    • Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity
    • Thoeni RF, Mueller-Lisse UG, Chan R, Do NK, Shyn PB. Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity. Radiology. 2000; 214: 483-90.
    • (2000) Radiology , vol.214 , pp. 483-490
    • Thoeni, R.F.1    Mueller-Lisse, U.G.2    Chan, R.3    Do, N.K.4    Shyn, P.B.5
  • 3
    • 0033622158 scopus 로고    scopus 로고
    • 111In-pentetreotide scintigraphy in the detection of insulinomas: importance of SPECT imaging
    • Schillaci O, Massa R, Scopinaro F. 111In-pentetreotide scintigraphy in the detection of insulinomas: importance of SPECT imaging. J Nucl Med. 2000; 41:459-62.
    • (2000) J Nucl Med , vol.41 , pp. 459-462
    • Schillaci, O.1    Massa, R.2    Scopinaro, F.3
  • 4
    • 0344394952 scopus 로고    scopus 로고
    • Somatostatin receptors 2 and 5 are the major somatostatin receptors in insulinomas: an in vivo and in vitro study
    • Bertherat J, Tenenbaum F, Perlemoine K, Videau C, Alberini JL, Richard B, et al. Somatostatin receptors 2 and 5 are the major somatostatin receptors in insulinomas: an in vivo and in vitro study. J Clin Endocrinol Metab. 2003; 88:5353-60.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5353-5360
    • Bertherat, J.1    Tenenbaum, F.2    Perlemoine, K.3    Videau, C.4    Alberini, J.L.5    Richard, B.6
  • 5
    • 0037907532 scopus 로고    scopus 로고
    • Concomitant expression of several peptide receptors in neuroendocrine tumours: molecular basis for in vivo multireceptor tumour targeting
    • Reubi JC, Waser B. Concomitant expression of several peptide receptors in neuroendocrine tumours: molecular basis for in vivo multireceptor tumour targeting. Eur J Nucl Med Mol Imaging. 2003; 30: 781-93.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 781-793
    • Reubi, J.C.1    Waser, B.2
  • 6
    • 34250635159 scopus 로고    scopus 로고
    • GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting
    • Korner M, Stockli M, Waser B, Reubi JC. GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. J Nucl Med. 2007; 48: 736-43.
    • (2007) J Nucl Med , vol.48 , pp. 736-743
    • Korner, M.1    Stockli, M.2    Waser, B.3    Reubi, J.C.4
  • 8
    • 0026648961 scopus 로고
    • Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
    • Eng J, Kleinman WA, Singh L, Singh G, Raufman JP. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem. 1992; 267: 7402-5.
    • (1992) J Biol Chem , vol.267 , pp. 7402-7405
    • Eng, J.1    Kleinman, W.A.2    Singh, L.3    Singh, G.4    Raufman, J.P.5
  • 9
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
    • Goke R, Fehmann HC, Linn T, Schmidt H, Krause M, Eng J, et al. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J Biol Chem. 1993; 268: 19650-5.
    • (1993) J Biol Chem , vol.268 , pp. 19650-19655
    • Goke, R.1    Fehmann, H.C.2    Linn, T.3    Schmidt, H.4    Krause, M.5    Eng, J.6
  • 10
    • 84864566823 scopus 로고    scopus 로고
    • Radiolabeled peptides: valuable tools for the detection and treatment of cance
    • Fani M,, Maecke H R, Okarvi SM. Radiolabeled peptides: valuable tools for the detection and treatment of cance. Theranostics. 2012; 2: 481-501.
    • (2012) Theranostics , vol.2 , pp. 481-501
    • Fani, M.1    Maecke, H.R.2    Okarvi, S.M.3
  • 11
    • 34250732525 scopus 로고    scopus 로고
    • [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting
    • Wild D, Behe M, Wicki A, Storch D, Waser B, Gotthardt M, et al. [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. J Nucl Med. 2006; 47:2025-33.
    • (2006) J Nucl Med , vol.47 , pp. 2025-2033
    • Wild, D.1    Behe, M.2    Wicki, A.3    Storch, D.4    Waser, B.5    Gotthardt, M.6
  • 13
    • 33751515577 scopus 로고    scopus 로고
    • A new technique for in vivo imaging of specific GLP-1 binding sites: first results in small rodents
    • Gotthardt M, Lalyko G, van Eerd-Vismale J, Keil B, Schurrat T, Hower M, et al. A new technique for in vivo imaging of specific GLP-1 binding sites: first results in small rodents. Regul Pept. 2006; 137: 162-7.
    • (2006) Regul Pept , vol.137 , pp. 162-167
    • Gotthardt, M.1    Lalyko, G.2    van Eerd-Vismale, J.3    Keil, B.4    Schurrat, T.5    Hower, M.6
  • 15
    • 77954986457 scopus 로고    scopus 로고
    • Exendin-4-based radiopharmaceuticals for glucagonlike peptide-1 receptor PET/CT and SPECT/CT
    • Wild D, Wicki A, Mansi R, Behe M, Keil B, Bernhardt P, et al. Exendin-4-based radiopharmaceuticals for glucagonlike peptide-1 receptor PET/CT and SPECT/CT. J Nucl Med. 2010; 51: 1059-67.
    • (2010) J Nucl Med , vol.51 , pp. 1059-1067
    • Wild, D.1    Wicki, A.2    Mansi, R.3    Behe, M.4    Keil, B.5    Bernhardt, P.6
  • 17
    • 84881409673 scopus 로고    scopus 로고
    • In Vivo Imaging of the Glucagonlike Peptide 1 Receptor in the Pancreas with 68Ga-Labeled DO3A-Exendin-4
    • Selvaraju RK, Velikyan I, Johansson L, Wu Z, Todorov I, Shively J, et al. In Vivo Imaging of the Glucagonlike Peptide 1 Receptor in the Pancreas with 68Ga-Labeled DO3A-Exendin-4. J Nucl Med. 2013; 54:1458-63.
    • (2013) J Nucl Med , vol.54 , pp. 1458-1463
    • Selvaraju, R.K.1    Velikyan, I.2    Johansson, L.3    Wu, Z.4    Todorov, I.5    Shively, J.6
  • 18
    • 80051751238 scopus 로고    scopus 로고
    • In vivo imaging of transplanted islets with 64Cu-DO3A-VS-Cys40-Exendin-4 by targeting GLP-1 receptor
    • Wu Z, Todorov I, Li L, Bading JR, Li Z, Nair I, et al. In vivo imaging of transplanted islets with 64Cu-DO3A-VS-Cys40-Exendin-4 by targeting GLP-1 receptor. Bioconjug Chem. 2011; 22: 1587-94.
    • (2011) Bioconjug Chem , vol.22 , pp. 1587-1594
    • Wu, Z.1    Todorov, I.2    Li, L.3    Bading, J.R.4    Li, Z.5    Nair, I.6
  • 19
    • 84861481526 scopus 로고    scopus 로고
    • Ex vivo imaging of pancreatic beta cells using a radiolabeled GLP-1 receptor agonist
    • Connolly BM, Vanko A, McQuade P, Guenther I, Meng X, Rubins D, et al. Ex vivo imaging of pancreatic beta cells using a radiolabeled GLP-1 receptor agonist. Mol Imaging Biol. 2012; 14: 79-87.
    • (2012) Mol Imaging Biol , vol.14 , pp. 79-87
    • Connolly, B.M.1    Vanko, A.2    McQuade, P.3    Guenther, I.4    Meng, X.5    Rubins, D.6
  • 20
    • 84870477312 scopus 로고    scopus 로고
    • Evaluation of an [18F]AlF-NOTA analog of Exendin-4 for imaging of GLP-1 receptor in insulinoma
    • Kiesewetter DO, Guo N, Guo J, et al. Evaluation of an [18F]AlF-NOTA analog of Exendin-4 for imaging of GLP-1 receptor in insulinoma. Theranostics. 2012; 2: 999-1009.
    • (2012) Theranostics , vol.2 , pp. 999-1009
    • Kiesewetter, D.O.1    Guo, N.2    Guo, J.3
  • 22
    • 84880343467 scopus 로고    scopus 로고
    • Development of a new thiol site-specific prosthetic group and its conjugation with [Cys40]-exendin-4 for in vivo targeting of insulinomas
    • Yue X, Kiesewetter DO, Guo J, Sun Z, Zhang X, Zhu L, et al. Development of a new thiol site-specific prosthetic group and its conjugation with [Cys40]-exendin-4 for in vivo targeting of insulinomas. Bioconjugate Chem. 2013; 24:1191-200.
    • (2013) Bioconjugate Chem , vol.24 , pp. 1191-1200
    • Yue, X.1    Kiesewetter, D.O.2    Guo, J.3    Sun, Z.4    Zhang, X.5    Zhu, L.6
  • 23
    • 84873551370 scopus 로고    scopus 로고
    • Development and evaluation of 18F-TTCO-Cys40-Exendin-4: a PET probe for imaging transplanted islets
    • Wu Z, Liu S, Hassink M, Nair I, Park R, Li L, et al. Development and evaluation of 18F-TTCO-Cys40-Exendin-4: a PET probe for imaging transplanted islets. J Nucl Med. 2013; 54: 244-51.
    • (2013) J Nucl Med , vol.54 , pp. 244-251
    • Wu, Z.1    Liu, S.2    Hassink, M.3    Nair, I.4    Park, R.5    Li, L.6
  • 24
    • 34548557001 scopus 로고    scopus 로고
    • 18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2): synthesis and microPET imaging of αvβ3 integrin expression
    • Wu Z, Li ZB, Cai W, He L, Chin FT, Li F, et al. 18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2): synthesis and microPET imaging of αvβ3 integrin expression. Eur J Nucl Med Mol Imaging. 2007; 34: 1823-31.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 1823-1831
    • Wu, Z.1    Li, Z.B.2    Cai, W.3    He, L.4    Chin, F.T.5    Li, F.6
  • 25
    • 0032476812 scopus 로고    scopus 로고
    • Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors
    • Mammen M, Choi S, Whitesides GM. Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors. Angew Chem Int Ed. 1998; 37: 2754-94.
    • (1998) Angew Chem Int Ed , vol.37 , pp. 2754-2794
    • Mammen, M.1    Choi, S.2    Whitesides, G.M.3
  • 26
    • 72449155498 scopus 로고    scopus 로고
    • An improved synthesis and biological evaluation of a new cage-like bifunctional chelator, 4-((8-amino-3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane-1-ylamino)methyl)be nzoic acid, for 64Cu radiopharmaceuticals
    • Cai H, Li Z, Huang CW, Park R, Shahinian AH, Conti PS. An improved synthesis and biological evaluation of a new cage-like bifunctional chelator, 4-((8-amino-3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane-1-ylamino)methyl)be nzoic acid, for 64Cu radiopharmaceuticals. Nucl Med Biol. 2010; 37: 57-65.
    • (2010) Nucl Med Biol , vol.37 , pp. 57-65
    • Cai, H.1    Li, Z.2    Huang, C.W.3    Park, R.4    Shahinian, A.H.5    Conti, P.S.6
  • 27
    • 84862685336 scopus 로고    scopus 로고
    • Trackable and Targeted Phage as Positron Emission Tomography (PET) Agent for Cancer Imaging
    • Li Z, Jin Q, Huang C, Dasa S, Chen L, Yap LP, et al. Trackable and Targeted Phage as Positron Emission Tomography (PET) Agent for Cancer Imaging. Theranostics. 2011; 1: 371-80.
    • (2011) Theranostics , vol.1 , pp. 371-380
    • Li, Z.1    Jin, Q.2    Huang, C.3    Dasa, S.4    Chen, L.5    Yap, L.P.6
  • 28
    • 84864403424 scopus 로고    scopus 로고
    • The efficient synthesis and biological evaluation of novel bi-functionalized sarcophagine for 64Cu radiopharmaceuticals
    • Liu S, Li D, Huang CW, Yap LP, Park R, Shan H, et al. The efficient synthesis and biological evaluation of novel bi-functionalized sarcophagine for 64Cu radiopharmaceuticals. Theranostics. 2012; 2: 589-96.
    • (2012) Theranostics , vol.2 , pp. 589-596
    • Liu, S.1    Li, D.2    Huang, C.W.3    Yap, L.P.4    Park, R.5    Shan, H.6
  • 29
    • 84870410818 scopus 로고    scopus 로고
    • Efficient Construction of PET/Fluorescence probe based on sarcophagine cage: An opportunity to integrate diagnosis with treatment
    • Liu S, Li D, Huang CW, Yap LP, Park R, Shan H, et al. Efficient Construction of PET/Fluorescence probe based on sarcophagine cage: An opportunity to integrate diagnosis with treatment. Mol Imaging Biol. 2012; 14: 718-24.
    • (2012) Mol Imaging Biol , vol.14 , pp. 718-724
    • Liu, S.1    Li, D.2    Huang, C.W.3    Yap, L.P.4    Park, R.5    Shan, H.6
  • 30
    • 0027209447 scopus 로고
    • Binding specificity and signal transduction of receptors for glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide on RINm5F insulinoma cells
    • Gallwitz B, Witt M, Folsch UR, Creutzfeldt W, Schmidt WE. Binding specificity and signal transduction of receptors for glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide on RINm5F insulinoma cells. J Mol Endocrinol. 1993; 10: 259-68.
    • (1993) J Mol Endocrinol , vol.10 , pp. 259-268
    • Gallwitz, B.1    Witt, M.2    Folsch, U.R.3    Creutzfeldt, W.4    Schmidt, W.E.5
  • 32
    • 78349295959 scopus 로고    scopus 로고
    • Quantitative assessment of beta-cell apoptosis and cell composition of isolated, undisrupted human islets by laser scanning cytometry
    • Todorov I, Nair I, Avakian-Mansoorian A, Rawson J, Omori K, Ito T, et al. Quantitative assessment of beta-cell apoptosis and cell composition of isolated, undisrupted human islets by laser scanning cytometry. Transplantation. 2010; 90: 836-42.
    • (2010) Transplantation , vol.90 , pp. 836-842
    • Todorov, I.1    Nair, I.2    Avakian-Mansoorian, A.3    Rawson, J.4    Omori, K.5    Ito, T.6
  • 33
    • 79955014687 scopus 로고    scopus 로고
    • Mono-PEGylated dimeric exendin-4 as high receptor binding and long-acting conjugates for type 2 anti-diabetes therapeutics
    • Kim TH, Jiang HH, Lee S, Youn YS, Park CW, Byun Y, et al. Mono-PEGylated dimeric exendin-4 as high receptor binding and long-acting conjugates for type 2 anti-diabetes therapeutics. Bioconjug Chem. 2012; 22: 625-32.
    • (2012) Bioconjug Chem , vol.22 , pp. 625-632
    • Kim, T.H.1    Jiang, H.H.2    Lee, S.3    Youn, Y.S.4    Park, C.W.5    Byun, Y.6
  • 34
  • 35
    • 79958042861 scopus 로고    scopus 로고
    • Design, synthesis and validation of integrin α2β1-targeted probe for microPET imaging of prostate cancer
    • Huang CW, Li Z, Cai H, Chen K, Shahinian T, Conti PS. Design, synthesis and validation of integrin α2β1-targeted probe for microPET imaging of prostate cancer. Eur J Nucl Med Mol Imaging. 2011; 38: 1313-22.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 1313-1322
    • Huang, C.W.1    Li, Z.2    Cai, H.3    Chen, K.4    Shahinian, T.5    Conti, P.S.6
  • 36
    • 33646011295 scopus 로고    scopus 로고
    • Gelatin-based plasma expander effectively reduces renal uptake of 111In-octreotide in mice and rats
    • van Eerd JE, Vegt E, Wetzels JF, Russel FG, Masereeuw R, Corstens FH, et al. Gelatin-based plasma expander effectively reduces renal uptake of 111In-octreotide in mice and rats. J Nucl Med. 2006; 47: 528-33.
    • (2006) J Nucl Med , vol.47 , pp. 528-533
    • van Eerd, J.E.1    Vegt, E.2    Wetzels, J.F.3    Russel, F.G.4    Masereeuw, R.5    Corstens, F.H.6
  • 37
    • 13944263708 scopus 로고    scopus 로고
    • Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor αvβ3-integrin expression
    • Chen X, Hou Y, Tohme M, Park R, Khankaldyyan V, Gonzales-Gomez I, et al. Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor αvβ3-integrin expression. J Nucl Med. 2004; 45: 1776-83.
    • (2004) J Nucl Med , vol.45 , pp. 1776-1783
    • Chen, X.1    Hou, Y.2    Tohme, M.3    Park, R.4    Khankaldyyan, V.5    Gonzales-Gomez, I.6
  • 38
    • 83755168263 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin α2β1 in prostate cancer with cell-penetrating-peptide-conjugated DGEA probe
    • Huang CW, Li Z, Conti PS. In vivo near-infrared fluorescence imaging of integrin α2β1 in prostate cancer with cell-penetrating-peptide-conjugated DGEA probe. J Nucl Med. 2011; 52: 1979-86.
    • (2011) J Nucl Med , vol.52 , pp. 1979-1986
    • Huang, C.W.1    Li, Z.2    Conti, P.S.3


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