Microfluidic temporal cell stimulation

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference

Volumn , Issue , 2008, Pages 674-676

  Andrew, Natalie ^a   Craig, David ^b   Urbanski, J P ^b   Gunawardena, Jeremy ^a   Thorsen, Todd ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cell; Complex systems; Microfluidics; Signal transduction

Indexed keywords

CELLS; LARGE SCALE SYSTEMS; PHYSIOLOGICAL MODELS; SIGNAL TRANSDUCTION; SIGNALING;

ANALYSIS OF SIGNAL; CELLULAR ENVIRONMENT; CELLULAR SIGNALING NETWORKS; CONCENTRATION PROFILES; LEVEL OF AUTOMATIONS; MICROFLUIDIC PLATFORMS; PHYSIOLOGICAL RESPONSE; PROGRAMMABLE SYSTEMS;

MICROFLUIDICS;

EID: 84902483041     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (7)

1. J. T. Mettetal, D. Muzzey, C. Gomez-Uribe, A. van Oudenaarden, The Frequency Dependence of Osmo-Adaptation in Saccharomyces cerevisiae, Science, 319, 482 (2008).
2. K. R. King, S. Wang, A. Jayaraman, M. L. Yarmush, M. Toner, Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments, Lab on a Chip, 8, 107 (2007).
3. R. E. Dolmetsch, K. L. Xu, R. S. Lewis, Calcium oscillations increase the efficiency and specificity of gene expression, Nature, 392, 933 (1998).
4. J. Olofsson, H. Bridle, J. Sinclair, D. Granfeldt, E Sahlin, O. Orwar, A chemical waveform synthesizer, PNAS, 102, 8097 (2005).
5. B. Kuczenski, P. R. LeDuc, W. C. Messner, Pressure-driven spatiotemporal control of the laminar flow interface in a microfluidic network, Lab on a Chip, 7, 647 (2007).
6. T. Meyer, L. Stryer, Molecular-model for receptor-stimulated calcium spiking, PNAS, 85, 5051 (1988).
7. J. Gunawardena, Signals and systems: Towards a systems biology of signal transduction, IEEE Proc, to appear 2008.