Study of mucoadhesive microsphere of pirfenidone for nasal drug delivery

Asian Journal of Pharmaceutics

Volumn 8, Issue 1, 2014, Pages 43-50

  Kashikar, Vrushali ^a   Dhole, Shashikant ^a   Kandekar, Ujawala ^a   Khose, Prachi ^a  

^a Department of Pharmaceutics Modern College of Pharmacy ^*  (India)

Author keywords

Cross linking method; nasal mucoadhesive microspheres; pirfenidone; spray drying

Indexed keywords

CHITOSAN; MICROSPHERE; MUCOADHESIVE MICROSPHERE; PIRFENIDONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STORAGE; DRUG SYNTHESIS; EMULSION; FIBROSING ALVEOLITIS; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HISTOPATHOLOGY; IN VITRO STUDY; NONHUMAN; NOSE MUCOSA; PARTICLE SIZE; SHEEP; SPRAY DRYING;

EID: 84902459226     PISSN: 09738398     EISSN: 1998409X     Source Type: Journal    
DOI: 10.4103/0973-8398.134099     Document Type: Article

References (12)

1. Kaurav H Harikumar SL Kaur A. Mucoadhesive microspheres as carriers in drug delivery: A review. Int J Drug Develop Res 2012;4:21-34.
2. Schaefer CJ Ruhrmund DW Pan L Seiwert SD Kossen K. Antifibrotic activities of pirfenidone in animal models. Eur Respir Rev 2011;20:85-97.
3. Noble PW Albera C Bradford WZ Costabel U Glassberg MK Kardatzke D et al. CAPACITY Study Group. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): Two randomised trials. Lancet 2011;377:1760-9.
4. Macías-Barragán J Sandoval-Rodríguez A Navarro-Partida J Armendáriz-Borunda J. The multifaceted role of pirfenidone and its novel targets. Fibrogenesis Tissue Repair 2010;3:16.
5. Raghu G Johnson WC Lockhart D Mageto Y. Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent pirfenidone: Results of a prospective open-label phase II study. Am J Respir Crit Care Med 1999;159:1061-9.
6. Rathananand M Kumar DS Shirwaikar A Kumar R Kumar DS Prasad RS. Preparation of mucoadhesive microspheres for nasal delivery by spray drying. Indian J Pharm Sci 2007;69:651-7.
7. Tadwee Imran AK Shahi SR Thube MW Shaikh AM Tribhuwan SD Mahajan HS. Spray dried nasal mucoadhesive microspheres of carbamazepine: Preparation and In vitro/Ex vivo evaluation. Res Pharmaceutica 2011;2:23-32.
8. Shahi SR Tribhuwan SD Tadwee Imran AK Gupta SK Zadbuke NS Shivanikar SS. Formulation of atenolol mucoadhesive microspheres for nasal delivery by spray drying technique: In vitro/Ex vivo evaluation. Der Pharmacia Sinica 2011;2:54-63.
9. Das MK Senapati PC. Furosemide-loaded alginate microspheres prepared by ionic cross-linking technique: Morphology and release characteristics. Indian J Pharm Sci 2008;70:77-84.
10. Patel VR Patel S Tank HM Jobanputra C Brahma D. Formulate and evaluate the mucoadhesive microsphere of HMG co-A reductase inhibitor for the treatment of hyperlipidemia. Int J Pharm Res Bio Sci 2012;1:283-308.
11. Jain SK Jain NK Gupta Y Jain A Jain D Chaurasia M. Mucoadhesive chitosan microspheres for non-invasive and improved nasal delivery of insulin. Indian J Pharm Sci 2007;69:498-504.
12. Yadav AV Mote HH. Development of biodegradable starch microspheres for intranasal delivery. Indian J Pharm Sci 2008;70:170-4.