Metformin sensitizes prostate cancer cells to radiation through EGFR/p-DNA-PKCS in vitro and in vivo

Radiation Research

Volumn 181, Issue 6, 2014, Pages 641-649

  Zhang, Tingting ^a,b   Zhang, Long ^c   Zhang, Tao ^d   Fan, Jinhai ^a,b   Wu, Kaijie ^a   Guan, Zhenfeng ^a   Wang, Xinyang ^b   Li, Lei ^a,b   Hsieh, Jer Tsong ^e   He, Dalin ^a,b   Guo, Peng ^a,b  

^a THE SECOND AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^d SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; HISTONE H2AX; METFORMIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CANCER SURVIVAL; CELL SURVIVAL; CLONOGENESIS; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; DOWN REGULATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION INDUCED NEOPLASM; RADIOSENSITIVITY; RADIOSENSITIZATION; SINGLE DRUG DOSE; TUMOR VOLUME;

ANIMALS; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; HISTONES; HUMANS; MALE; METFORMIN; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION TOLERANCE; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84902437461     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR13561.1     Document Type: Article

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