Deep sequencing of cancer-related genes revealed GNAS mutations to be associated with intraductal papillary mucinous neoplasms and its main pancreatic duct dilation

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Takano, Shinichi ^a   Fukasawa, Mitsuharu ^a   Maekawa, Shinya ^a   Kadokura, Makoto ^a   Miura, Mika ^a   Shindo, Hiroko ^a   Takahashi, Ei ^a   Sato, Tadashi ^a   Enomoto, Nobuyuki ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AMPLICON; ARTICLE; CANCER RELATED GENE; CANCER TISSUE; CHRONIC PANCREATITIS; DNA EXTRACTION; FEMALE; GENE AMPLIFICATION; GENE MUTATION; GENE SEQUENCE; GNAS GENE; HUMAN; HUMAN TISSUE; INTRADUCTAL PAPILLARY MUCINOUS TUMOR; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; PANCREAS DUCT; PANCREAS FUNCTION DISORDER; PANCREAS JUICE; PANCREATIC DUCT DILATION; SEQUENCE ANALYSIS; TUMOR GENE; VERY ELDERLY; ADENOCARCINOMA, MUCINOUS; BIOLOGICAL MODEL; CANCER GRADING; CANCER STAGING; CARCINOMA, PANCREATIC DUCTAL; CARCINOMA, PAPILLARY; GENETIC ASSOCIATION; GENETICS; HIGH THROUGHPUT SEQUENCING; MAGNETIC RESONANCE ANGIOGRAPHY; MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY; MIDDLE AGED; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; TUMOR VOLUME;

GNAS PROTEIN, HUMAN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ADENOCARCINOMA, MUCINOUS; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, PANCREATIC DUCTAL; CARCINOMA, PAPILLARY; CHOLANGIOPANCREATOGRAPHY, MAGNETIC RESONANCE; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC ASSOCIATION STUDIES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; MUTATION; NEOPLASM GRADING; NEOPLASM STAGING; PANCREATIC DUCTS; TUMOR BURDEN;

EID: 84902436224     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098718     Document Type: Article

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