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Volumn 10, Issue 2, 2014, Pages 223-228

Clinical Experience of Life-Threatening Dabigatran-Related Bleeding at a Large, Tertiary Care, Academic Medical Center: A Case Series

Author keywords

Dabigatran; New oral anticoagulant; Reversal

Indexed keywords

CREATININE; DABIGATRAN; FRESH FROZEN PLASMA; HEMOGLOBIN; INFUSION FLUID; ANTITHROMBIN; BENZIMIDAZOLE DERIVATIVE; BETA ALANINE;

EID: 84902379444     PISSN: 15569039     EISSN: 19376995     Source Type: Journal    
DOI: 10.1007/s13181-013-0364-1     Document Type: Article
Times cited : (23)

References (21)
  • 1
    • 84870595907 scopus 로고    scopus 로고
    • Editorial. Globalization of the epidemiologic, clinical, and financial burden of atrial fibrillation
    • Boriani G, Diemberger I (2012) Editorial. Globalization of the epidemiologic, clinical, and financial burden of atrial fibrillation. Chest 142(6): 1368-1370.
    • (2012) Chest , vol.142 , Issue.6 , pp. 1368-1370
    • Boriani, G.1    Diemberger, I.2
  • 2
    • 84856745317 scopus 로고    scopus 로고
    • Antithrombotic therapy for atrial fibrillation: antithrombotic therapy and prevention of thrombosis, 9th edn: American College of Chest Physicians evidence-based clinical practice guidelines
    • You JJ, Singer DE, Howard PA et al (2012) Antithrombotic therapy for atrial fibrillation: antithrombotic therapy and prevention of thrombosis, 9th edn: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 141(2 Suppl): e531S-e575S.
    • (2012) Chest , vol.141 , Issue.2 SUPPL.
    • You, J.J.1    Singer, D.E.2    Howard, P.A.3
  • 5
    • 84902369236 scopus 로고    scopus 로고
    • Theheart. org. [Clinical conditions > Arrhythmia/EP > Arrhythmia/EP] Accessed 1 Mar 2013
    • Wood S (2011) Dabigatran: 260 fatal bleeds since approval worldwide. Theheart. org. [Clinical conditions > Arrhythmia/EP > Arrhythmia/EP]. http://www. theheart. org/article/1314809. do. Accessed 1 Mar 2013.
    • (2011) Dabigatran: 260 fatal bleeds since approval worldwide
    • Wood, S.1
  • 6
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation
    • Connolly SJ, Ezekowitz MD, Yusuf S et al (2009) Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 361(12): 1139-1151.
    • (2009) N Engl J Med , vol.361 , Issue.12 , pp. 1139-1151
    • Connolly, S.J.1    Ezekowitz, M.D.2    Yusuf, S.3
  • 7
    • 84875952556 scopus 로고    scopus 로고
    • Case report: fatality in a patient treated with dabigatran
    • Schattner A, Kozak N, Friedman J (2013) Case report: fatality in a patient treated with dabigatran. Am J Emerg Med 31(2): 443. e1-443. e2.
    • (2013) Am J Emerg Med , vol.31 , Issue.2
    • Schattner, A.1    Kozak, N.2    Friedman, J.3
  • 8
    • 84857759555 scopus 로고    scopus 로고
    • Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding
    • Warkentin TE, Margetts P, Connolly SJ et al (2012) Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding. Blood 119(9): 2172-2174.
    • (2012) Blood , vol.119 , Issue.9 , pp. 2172-2174
    • Warkentin, T.E.1    Margetts, P.2    Connolly, S.J.3
  • 9
    • 84859549864 scopus 로고    scopus 로고
    • Clinical challenges in a patient with dabigatran-induced fatal hemorrhage
    • Cano EL, Miyares MA (2012) Clinical challenges in a patient with dabigatran-induced fatal hemorrhage. J Geriatr Pharmacother 10: 160-163.
    • (2012) J Geriatr Pharmacother , vol.10 , pp. 160-163
    • Cano, E.L.1    Miyares, M.A.2
  • 10
    • 84864762326 scopus 로고    scopus 로고
    • Hemopericardium and cardiac tamponade associated with dabigatran use
    • Dy EA, Shiltz DL (2012) Hemopericardium and cardiac tamponade associated with dabigatran use. Ann Pharmacother 46(7-8): e18.
    • (2012) Ann Pharmacother , vol.46 , Issue.7-8
    • Dy, E.A.1    Shiltz, D.L.2
  • 11
    • 79960955075 scopus 로고    scopus 로고
    • The use of dabigatran in elderly patients
    • Legrand M, Mateo J, Aribaud A et al (2011) The use of dabigatran in elderly patients. Arch Intern Med 171(14): 1285-1288.
    • (2011) Arch Intern Med , vol.171 , Issue.14 , pp. 1285-1288
    • Legrand, M.1    Mateo, J.2    Aribaud, A.3
  • 12
    • 84860746568 scopus 로고    scopus 로고
    • Neurosurgical complications of direct thrombin inhibitors-catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran
    • Garber ST, Sivakumar W, Schmidt RH (2012) Neurosurgical complications of direct thrombin inhibitors-catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran. J Neurosurg 116(5): 1093-1096.
    • (2012) J Neurosurg , vol.116 , Issue.5 , pp. 1093-1096
    • Garber, S.T.1    Sivakumar, W.2    Schmidt, R.H.3
  • 13
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects
    • Eerenberg ES, Kamphuisen PW, Sijpkens MK et al (2011) Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 124(14): 1573-1579.
    • (2011) Circulation , vol.124 , Issue.14 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3
  • 14
    • 84856214360 scopus 로고    scopus 로고
    • Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran
    • Zhou W, Schwarting S, Illanes S et al (2011) Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran. Stroke 42: 3594-3599.
    • (2011) Stroke , vol.42 , pp. 3594-3599
    • Zhou, W.1    Schwarting, S.2    Illanes, S.3
  • 15
    • 84856784474 scopus 로고    scopus 로고
    • Antithrombotic therapy and prevention of thrombosis, 9th edn: American College of Chest Physicians evidence-based clinical practice guidelines
    • Ageno W, Gallus AS, Wittkowsky A et al (2012) Antithrombotic therapy and prevention of thrombosis, 9th edn: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 141(2 Suppl): e44S-e88S.
    • (2012) Chest , vol.141 , Issue.2 SUPPL.
    • Ageno, W.1    Gallus, A.S.2    Wittkowsky, A.3
  • 16
    • 84876666915 scopus 로고    scopus 로고
    • Reversing dabigatran in a life-threatening bleed occurring during cardiac ablation with factor eight inhibitor bypassing activity
    • Dager WE, Gosselin RC, Roberts J (2013) Reversing dabigatran in a life-threatening bleed occurring during cardiac ablation with factor eight inhibitor bypassing activity. Crit Care Med 41: 1-5.
    • (2013) Crit Care Med , vol.41 , pp. 1-5
    • Dager, W.E.1    Gosselin, R.C.2    Roberts, J.3
  • 17
    • 84867699158 scopus 로고    scopus 로고
    • Hemorrhagic complications associated with dabigatran use
    • Chen BC, Viny AD, Garlich FM et al (2012) Hemorrhagic complications associated with dabigatran use. Clin Toxicol (Phila) 50: 854-857.
    • (2012) Clin Toxicol (Phila) , vol.50 , pp. 854-857
    • Chen, B.C.1    Viny, A.D.2    Garlich, F.M.3
  • 18
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • van Ryn J, Stangier J, Haetter S et al (2010) Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 103: 1116-1127.
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • van Ryn, J.1    Stangier, J.2    Haetter, S.3
  • 21
    • 80052408267 scopus 로고    scopus 로고
    • Dabigatran anticoagulant activity is neutralized by an antibody selective to dabigatran in in vitro and in vivo models
    • (abstr)
    • van Ryn J, Litzenburger T, Waterman A et al (2011) Dabigatran anticoagulant activity is neutralized by an antibody selective to dabigatran in in vitro and in vivo models. J Am Coll Cardiol 57(14): E1130 (abstr).
    • (2011) J Am Coll Cardiol , vol.57 , Issue.14
    • van Ryn, J.1    Litzenburger, T.2    Waterman, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.