In vivo investigation of twin-screw extruded lipid implants for vaccine delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 87, Issue 2, 2014, Pages 338-346

  Even, Marie Paule ^a   Young, Katie ^b   Winter, Gerhard ^a   Hook, Sarah ^b   Engert, Julia ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Lipid implants; Ovalbumin; Quil A; Sustained release of antigen; Twin screw extrusion; Vaccine delivery

Indexed keywords

ANTIGEN; CHOLESTEROL; DRUG CARRIER; GAMMA INTERFERON; GLYCEROL; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 4; LIPID; LIPOSOME; OVALBUMIN; PHOSPHATIDYLCHOLINE; QUIL A; VACCINE; BIOLOGICAL MARKER; DRUG IMPLANT; SAPONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG IMPLANT; DRUG RELEASE; FEMALE; FREEZE DRYING; HUMORAL IMMUNITY; HYDRATION; IMMUNE RESPONSE; IN VIVO STUDY; LIPID MEMBRANE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PROCEDURES; SUSTAINED DRUG RELEASE; TWIN SCREW EXTRUSION; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; IMMUNIZATION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MEDICINAL CHEMISTRY; PHARMACEUTICS; SOLUBILITY; SUBCUTANEOUS DRUG ADMINISTRATION; SWINE; TIME; TRANSGENIC MOUSE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG IMPLANTS; FEMALE; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNIZATION; IMMUNOGLOBULIN G; INJECTIONS, SUBCUTANEOUS; INTERFERON-GAMMA; INTERLEUKIN-4; LIPIDS; LIPOSOMES; LYMPHOCYTE ACTIVATION; MICE, INBRED C57BL; MICE, TRANSGENIC; OVALBUMIN; SAPONINS; SOLUBILITY; SWINE; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; VACCINES;

EID: 84902358927     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.02.014     Document Type: Article

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