The effects of equal caloric high fat and western diet on metabolic syndrome, oxidative stress and vascular endothelial function in mice

Acta Physiologica

Volumn 211, Issue 3, 2014, Pages 515-527

  Heinonen, I ^a,b,c   Rinne, P ^a   Ruohonen, S T ^a   Ruohonen, S ^a,c   Ahotupa, M ^d   Savontaus, E ^a,e  

^a UNIVERSITY OF TURKU   (Finland)

^b TURKU PET CENTRE   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d MCA Research Laboratory Ltd   (Finland)

^e TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Adiposity; High fat and Western diets; Metabolism; Oxidative stress; Vascular function

Indexed keywords

AGOUTI RELATED PROTEIN; CHOLESTEROL; CORTICOTROPIN RELEASING FACTOR; FATTY ACID; GLUCOSE; INSULIN; MESSENGER RNA; NEUROPEPTIDE Y; NITRATE; NITRITE; PROOPIOMELANOCORTIN; SUCROSE; TRIACYLGLYCEROL; BIOLOGICAL MARKER; VASODILATOR AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTICLE; BLOOD VESSEL REACTIVITY; BODY COMPOSITION; CALORIC INTAKE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CHOLESTEROL LIVER LEVEL; CONTROLLED STUDY; DIET RESTRICTION; FATTY ACID BLOOD LEVEL; FOOD INTAKE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; INSULIN BLOOD LEVEL; LIPID DIET; LIPID LIVER LEVEL; LOW FAT DIET; MALE; MESENTERIC ARTERY; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; RESISTANCE BLOOD VESSEL; SUBCUTANEOUS FAT; SUGAR INTAKE; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; VASCULAR ENDOTHELIUM; WESTERN DIET; ANIMAL; BLOOD; BLOOD PRESSURE; BODY WEIGHT; C57BL MOUSE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIVER; METABOLISM; NUTRITIONAL STATUS; PATHOPHYSIOLOGY; RISK FACTOR; TIME; VASODILATATION;

ADIPOSITY; ANIMALS; BIOLOGICAL MARKERS; BLOOD PRESSURE; BODY WEIGHT; DIET, HIGH-FAT; DIET, WESTERN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENERGY INTAKE; GENE EXPRESSION REGULATION; LIVER; MALE; METABOLIC SYNDROME X; MICE, INBRED C57BL; NUTRITIONAL STATUS; OXIDATIVE STRESS; RISK FACTORS; TIME FACTORS; VASODILATION; VASODILATOR AGENTS;

EID: 84902344139     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12253     Document Type: Article

References (45)

1. Ahotupa, M., Mäntylä, E. & Kangas, L. 1997. Antioxidant properties of the triphenylethylene antiestrogen drug toremifene. Naunyn-Schmiedeberg's Arch Pharmacol 356, 297-302.
2. Aldhahi, W. & Hamdy, O. 2003. Adipokines, inflammation, and the endothelium in diabetes. Curr Diab Rep 3, 293-298.
3. Alonso, L.C., Watanabe, Y., Stefanovski, D., Lee, E.J., Singamsetty, S., Romano, L.C., Zou, B., Garcia-Ocana, A., Bergman, R.N. & O'Donnell, C.P. 2012. Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice. Obesity (Silver Spring) 20, 1403-1412.
4. Andrikopoulos, S., Blair, A.R., Deluca, N., Fam, B.C. & Proietto, J. 2008. Evaluating the glucose tolerance test in mice. Am J Physiol Endocrinol Metab 295, E1323-E1332.
5. Anstee, Q.M. & Goldin, R.D. 2006. Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int J Exp Pathol 87, 1-16.
6. Archer, Z.A. & Mercer, J.G. 2007. Brain responses to obesogenic diets and diet-induced obesity. Proc Nutr Soc 66, 124-130.
7. Ayer, J.G., Harmer, J.A., David, C., Steinbeck, S., Seale, J.P. & Celermajer, D.S. 2011. Severe obesity is associated with impaired arterial smooth muscle function in young adults. Obesity (Silver Spring) 19, 54-60.
8. Berrington, D.G., Hartge, P., Cerhan, J.R., Flint, A.J., Hannan, L., MacInnis, R.J., Moore, S.C., Tobias, G.S., Anton-Culver, H., Freeman, L.B. et al. 2010. Body-mass index and mortality among 1.46 million white adults. N Engl J Med 363, 2211-2219.
9. Brand-Miller, J., McMillan-Price, J., Steinbeck, K. & Caterson, I. 2009. Dietary glycemic index: health implications. J Am Coll Nutr 28(Suppl), 446S-449S.
10. Bray, G.A., Smith, S.R., de Jonge, L., Xie, H., Rood, J., Martin, C.K., Most, M., Brock, C., Mancuso, S. & Redman, L.M. 2012. Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating: a randomized controlled trial. JAMA 307, 47-55.
11. Caballero, A.E., Arora, S., Saouaf, R., Lim, S.C., Smakowski, P., Park, J.Y., King, G.L., Logerfo, F.W., Horton, E.S. & Veves, A. 1999. Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Diabetes 48, 1856-1862.
12. Delaey, C., Boussery, K. & Van de Voorde, J 2002. Contractility studies on isolated bovine choroidal small arteries: determination of the active and passive wall tension-internal circumference relation. Exp Eye Res 75, 243-248.
13. Despres, J.P. & Lemieux, I. 2006. Abdominal obesity and metabolic syndrome. Nature 444, 881-887.
14. Gordon, J.L., Lavoie, K.L., Arsenault, A., Ditto, B. & Bacon, S.L. 2008. Health behaviors and endothelial function. J Behav Med 31, 5-21.
15. Grundy, S.M. 2012. Pre-diabetes, metabolic syndrome, and cardiovascular risk. J Am Coll Cardiol 59, 635-643.
16. Hamdy, O. 2005. Lifestyle modification and endothelial function in obese subjects. Expert Rev Cardiovasc Ther 3, 231-241.
17. Hink, U., Li, H., Mollnau, H., Oelze, M., Matheis, E., Hartmann, M., Skatchkov, M., Thaiss, F., Stahl, R.A., Warnholtz, A., Meinertz, T., Griendling, K., Harrison, D.G., Forstermann, U. & Munzel, T. 2001. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 88, E14-E22.
18. Howitt, L., Grayson, T.H., Morris, M.J., Sandow, S.L. & Murphy, T.V. 2012. Dietary obesity increases NO and inhibits BKCa-mediated, endothelium-dependent dilation in rat cremaster muscle artery: association with caveolins and caveolae. Am J Physiol Heart Circ Physiol 302, H2464-H2476.
19. Joyner, M.J. & Green, D.J. 2009. Exercise protects the cardiovascular system: effects beyond traditional risk factors. J Physiol 587, 5551-5558.
20. Kong, A.P., Chan, R.S., Nelson, E.A. & Chan, J.C. 2011. Role of low-glycemic index diet in management of childhood obesity. Obes Rev 12, 492-498.
21. Kotronen, A., Westerbacka, J., Bergholm, R., Pietilainen, K.H. & Yki-Jarvinen, H. 2007. Liver fat in the metabolic syndrome. J Clin Endocrinol Metab 92, 3490-3497.
22. Kumashiro, N., Tamura, Y., Uchida, T., Ogihara, T., Fujitani, Y., Hirose, T., Mochizuki, H., Kawamori, R. & Watada, H. 2008. Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance. Diabetes 57, 2083-2091.
23. Kumashiro, N., Erion, D.M., Zhang, D., Kahn, M., Beddow, S.A., Chu, X., Still, C.D., Gerhard, G.S., Han, X., Dziura, J., Petersen, K.F., Samuel, V.T. & Shulman, G.I. 2011. Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. Proc Natl Acad Sci USA 108, 16381-16385.
24. Lin, S., Storlien, L.H. & Huang, X.F. 2000. Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain. Brain Res 875, 89-95.
25. Mozaffarian, D., Hao, T., Rimm, E.B., Willett, W.C. & Hu, F.B. 2011. Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med 364, 2392-2404.
26. Napoli, C., Crudele, V., Soricelli, A., Al-Omran, M., Vitale, N., Infante, T. & Mancini, F.P. 2012. Primary prevention of atherosclerosis: a clinical challenge for the reversal of epigenetic mechanisms? Circulation 125, 2363-2373.
27. Peiper, U., Schmidt, E., Laven, R. & Griebel, L. 1973. Length-tension relationships in resting and activated vascular smooth muscle fibres. Pflugers Arch 340, 113-122.
28. Persson, P.B. 2013. Good publication practice in physiology 2013: revised author guidelines for Acta Physiolociga. Acta Physiol (Oxf) 209, 250-253.
29. Pruis, M.G., Lendvai, A., Bloks, V.W., Zwier, M.V., Baller, J.F., de Bruin, A., Groen, A.K. & Plosch, T. 2014. Maternal western diet primes non-alcoholic fatty liver disease in adult mouse offspring. Acta Physiol (Oxf) 210, 215-227.
30. Rinne, P., Nordlund, W., Heinonen, I., Penttinen, A.M., Saraste, A., Ruohonen, S.T., Makela, S., Vahatalo, L., Kaipio, K., Cai, M., Hruby, V.J., Ruohonen, S. & Savontaus, E. 2012. alpha-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction. Cardiovasc Res 97, 360-368.
31. Romero-Corral, A., Sert-Kuniyoshi, F.H., Sierra-Johnson, J., Orban, M., Gami, A., Davison, D., Singh, P., Pusalavidyasagar, S., Huyber, C., Votruba, S., Lopez-Jimenez, F., Jensen, M.D. & Somers, V.K. 2010. Modest visceral fat gain causes endothelial dysfunction in healthy humans. J Am Coll Cardiol 56, 662-666.
32. Ruohonen, S.T., Pesonen, U., Moritz, N., Kaipio, K., Roytta, M., Koulu, M. & Savontaus, E. 2008. Transgenic mice overexpressing neuropeptide Y in noradrenergic neurons: a novel model of increased adiposity and impaired glucose tolerance. Diabetes 57, 1517-1525.
33. Sampey, B.P., Vanhoose, A.M., Winfield, H.M., Freemerman, A.J., Muehlbauer, M.J., Fueger, P.T., Newgard, C.B. & Makowski, L. 2011. Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high-fat diet. Obesity (Silver Spring) 19, 1109-1117.
34. Samuel, V.T. & Shulman, G.I. 2012. Mechanisms for insulin resistance: common threads and missing links. Cell 148, 852-871.
35. Sanchez-Lasheras, C., Konner, A.C. & Bruning, J.C. 2010.Integrative neurobiology of energy homeostasis-neurocircuits, signals and mediators. Front Neuroendocrinol 31, 4-15.
36. Shea, J.L., King, M.T., Yi, Y., Gulliver, W. & Sun, G. 2012. Body fat percentage is associated with cardiometabolic dysregulation in BMI-defined normal weight subjects. Nutr Metab Cardiovasc Dis 22, 741-747.
37. Smith, B.W. & Adams, L.A. 2011. Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment. Nat Rev Endocrinol 7, 456-465.
38. Spradley, F.T., Kang, K.T. & Pollock, J.S. 2013. Short-term hypercaloric diet induces blunted aortic vasoconstriction and enhanced vasorelaxation via increased nitric oxide synthase 3 activity and expression in Dahl salt-sensitive rats. Acta Physiol (Oxf) 207, 358-368.
39. Sumithran, P., Prendergast, L.A., Delbridge, E., Purcell, K., Shulkes, A., Kriketos, A. & Proietto, J. 2011. Long-term persistence of hormonal adaptations to weight loss. N Engl J Med 365, 1597-1604.
40. Ueno, N., Kashiwamura, S., Ueda, H., Okamura, H., Tsuji, N.M., Hosohara, K., Kotani, J. & Marukawa, S. 2005. Role of interleukin 18 in nitric oxide production and pancreatic damage during acute pancreatitis. Shock 24, 564-570.
41. Valassi, E., Scacchi, M. & Cavagnini, F. 2008. Neuroendocrine control of food intake. Nutr Metab Cardiovasc Dis 18, 158-168.
42. Velloso, L.A. & Schwartz, M.W. 2011. Altered hypothalamic function in diet-induced obesity. Int J Obes (Lond) 35, 1455-1465.
43. Vial, G., Dubouchaud, H., Couturier, K., Cottet-Rousselle, C., Taleux, N., Athias, A., Galinier, A., Casteilla, L. & Leverve, X.M. 2011. Effects of a high-fat diet on energy metabolism and ROS production in rat liver. J Hepatol 54, 348-356.
44. Williams, K.J. 2008. Molecular processes that handle - and mishandle - dietary lipids. J Clin Invest 118, 3247-3259.
45. Zhang, H., Dellsperger, K.C. & Zhang, C. 2012. The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: an update. Basic Res Cardiol 107, 237.