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Volumn 4, Issue APRIL, 2014, Pages

Circulating sCD36 is associated with unhealthy fat distribution and elevated circulating triglycerides in morbidly obese individuals

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CD36 ANTIGEN; GLUCOSE; INSULIN; PLASMA PROTEIN; PROTEIN YKL 40; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; C PEPTIDE; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; YKL 40;

EID: 84902257688     PISSN: None     EISSN: 20444052     Source Type: Journal    
DOI: 10.1038/nutd.2014.11     Document Type: Article
Times cited : (21)

References (48)
  • 1
    • 35848935201 scopus 로고    scopus 로고
    • Cause-specific excess deaths associated with underweight, overweight, and obesity
    • Flegal KM, Graubard BI, Williamson DF, Gail MH. Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA 2007; 298: 2028-2037.
    • (2007) JAMA , vol.298 , pp. 2028-2037
    • Flegal, K.M.1    Graubard, B.I.2    Williamson, D.F.3    Gail, M.H.4
  • 3
    • 0034569866 scopus 로고    scopus 로고
    • Obesity: Preventing and managing the global epidemic. Report of a WHO consultation
    • 1-253
    • Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000; 894: i-xii, 1-253.
    • (2000) World Health Organ Tech Rep Ser. , vol.894
  • 4
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; And International Association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009; 120: 1640-1645.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3    Zimmet, P.Z.4    Cleeman, J.I.5    Donato, K.A.6
  • 6
    • 84861591910 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
    • Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 2012; 142: 1592-1609.
    • (2012) Gastroenterology , vol.142 , pp. 1592-1609
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6
  • 7
    • 84877854022 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease
    • Gaggini M, Morelli M, Buzzigoli E, DeFronzo RA, Bugianesi E, Gastaldelli A. Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease. Nutrients 2013; 5: 1544-1560.
    • (2013) Nutrients , vol.5 , pp. 1544-1560
    • Gaggini, M.1    Morelli, M.2    Buzzigoli, E.3    Defronzo, R.A.4    Bugianesi, E.5    Gastaldelli, A.6
  • 8
    • 84862270029 scopus 로고    scopus 로고
    • Ectopic fat and insulin resistance: Pathophysiology and effect of diet and lifestyle interventions
    • Snel M, Jonker JT, Schoones J, Lamb H, de Roos A, Pijl H et al. Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions. Int J Endocrinol 2012; 2012: 983814.
    • (2012) Int J Endocrinol , vol.2012 , pp. 983814
    • Snel, M.1    Jonker, J.T.2    Schoones, J.3    Lamb, H.4    De Roos, A.5    Pijl, H.6
  • 9
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993; 259: 87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 11
    • 1442275317 scopus 로고    scopus 로고
    • Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
    • Pickup JC. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 2004; 27: 813-823.
    • (2004) Diabetes Care , vol.27 , pp. 813-823
    • Pickup, J.C.1
  • 12
    • 58149500277 scopus 로고    scopus 로고
    • Emerging role of adipose tissue hypoxia in obesity and insulin resistance
    • Ye J. Emerging role of adipose tissue hypoxia in obesity and insulin resistance. Int J Obes (Lond) 2009; 33: 54-66.
    • (2009) Int J Obes (Lond) , vol.33 , pp. 54-66
    • Ye, J.1
  • 13
    • 84876179073 scopus 로고    scopus 로고
    • Dyslipidemia in obesity: Mechanisms and potential targets
    • Klop B, Elte JW, Cabezas MC. Dyslipidemia in obesity: mechanisms and potential targets. Nutrients 2013; 5: 1218-1240.
    • (2013) Nutrients , vol.5 , pp. 1218-1240
    • Klop, B.1    Elte, J.W.2    Cabezas, M.C.3
  • 14
    • 79952451443 scopus 로고    scopus 로고
    • Obesity, insulin resistance and free fatty acids
    • Boden G. Obesity, insulin resistance and free fatty acids. Curr Opin Endocrinol Diabetes Obes 2011; 18: 139-143.
    • (2011) Curr Opin Endocrinol Diabetes Obes , vol.18 , pp. 139-143
    • Boden, G.1
  • 16
    • 84868266750 scopus 로고    scopus 로고
    • CD36 level and trafficking are determinants of lipolysis in adipocytes
    • Zhou D, Samovski D, Okunade AL, Stahl PD, Abumrad NA, Su X. CD36 level and trafficking are determinants of lipolysis in adipocytes. FASEB J 2012; 26: 4733-4742.
    • (2012) FASEB J , vol.26 , pp. 4733-4742
    • Zhou, D.1    Samovski, D.2    Okunade, A.L.3    Stahl, P.D.4    Abumrad, N.A.5    Su, X.6
  • 17
    • 4344685789 scopus 로고    scopus 로고
    • CD36 in myocytes channels fatty acids to a lipase-accessible triglyceride pool that is related to cell lipid and insulin responsiveness
    • Bastie CC, Hajri T, Drover VA, Grimaldi PA, Abumrad NA. CD36 in myocytes channels fatty acids to a lipase-accessible triglyceride pool that is related to cell lipid and insulin responsiveness. Diabetes 2004; 53: 2209-2216.
    • (2004) Diabetes , vol.53 , pp. 2209-2216
    • Bastie, C.C.1    Hajri, T.2    Drover, V.A.3    Grimaldi, P.A.4    Abumrad, N.A.5
  • 18
    • 36849037401 scopus 로고    scopus 로고
    • Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity
    • Koonen DP, Jacobs RL, Febbraio M, Young ME, Soltys CL, Ong H et al. Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes 2007; 56: 2863-2871.
    • (2007) Diabetes , vol.56 , pp. 2863-2871
    • Koonen, D.P.1    Jacobs, R.L.2    Febbraio, M.3    Young, M.E.4    Soltys, C.L.5    Ong, H.6
  • 20
    • 84864062804 scopus 로고    scopus 로고
    • Role of the gut in lipid homeostasis
    • Abumrad NA, Davidson NO. Role of the gut in lipid homeostasis. Physiol Rev 2012; 92: 1061-1085.
    • (2012) Physiol Rev , vol.92 , pp. 1061-1085
    • Abumrad, N.A.1    Davidson, N.O.2
  • 21
    • 84861211655 scopus 로고    scopus 로고
    • Scavenger receptor CD36 expression contributes to adipose tissue inflammation and cell death in diet-induced obesity
    • Cai L, Wang Z, Ji A, Meyer JM, van der Westhuyzen DR. Scavenger receptor CD36 expression contributes to adipose tissue inflammation and cell death in diet-induced obesity. PLoS One 2012; 7: e36785.
    • (2012) PLoS One , vol.7
    • Cai, L.1    Wang, Z.2    Ji, A.3    Meyer, J.M.4    Van Der Westhuyzen, D.R.5
  • 22
    • 33748667302 scopus 로고    scopus 로고
    • Identification of the oxidized low-density lipoprotein scavenger receptor CD36 in plasma: A novel marker of insulin resistance
    • Handberg A, Levin K, Hojlund K, Beck-Nielsen H. Identification of the oxidized low-density lipoprotein scavenger receptor CD36 in plasma: a novel marker of insulin resistance. Circulation 2006; 114: 1169-1176.
    • (2006) Circulation , vol.114 , pp. 1169-1176
    • Handberg, A.1    Levin, K.2    Hojlund, K.3    Beck-Nielsen, H.4
  • 23
    • 79953712650 scopus 로고    scopus 로고
    • Soluble CD36- a marker of the (pathophysiological) role of CD36 in the metabolic syndrome?
    • Koonen DP, Jensen MK, Handberg A. Soluble CD36- a marker of the (pathophysiological) role of CD36 in the metabolic syndrome? Arch Physiol Biochem 2011; 117: 57-63.
    • (2011) Arch Physiol Biochem , vol.117 , pp. 57-63
    • Koonen, D.P.1    Jensen, M.K.2    Handberg, A.3
  • 24
    • 84857628613 scopus 로고    scopus 로고
    • Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population
    • Handberg A, Hojlund K, Gastaldelli A, Flyvbjerg A, Dekker JM, Petrie J et al. Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population. J Intern Med 2012; 271: 294-304.
    • (2012) J Intern Med , vol.271 , pp. 294-304
    • Handberg, A.1    Hojlund, K.2    Gastaldelli, A.3    Flyvbjerg, A.4    Dekker, J.M.5    Petrie, J.6
  • 25
    • 84873478046 scopus 로고    scopus 로고
    • High sCD36 plasma level is associated with steatosis and its severity in patients with genotype 1 chronic hepatitis C
    • Petta S, Handberg A, Marchesini G, Camma C, Di Marco V, Cabibi D et al. High sCD36 plasma level is associated with steatosis and its severity in patients with genotype 1 chronic hepatitis C. J Viral Hepat 2013; 20: 174-182.
    • (2013) J Viral Hepat , vol.20 , pp. 174-182
    • Petta, S.1    Handberg, A.2    Marchesini, G.3    Camma, C.4    Di Marco, V.5    Cabibi, D.6
  • 27
    • 38949088666 scopus 로고    scopus 로고
    • Soluble CD36 and risk markers of insulin resistance and atherosclerosis are elevated in polycystic ovary syndrome and significantly reduced during pioglitazone treatment
    • Glintborg D, Hojlund K, Andersen M, Henriksen JE, Beck-Nielsen H, Handberg A. Soluble CD36 and risk markers of insulin resistance and atherosclerosis are elevated in polycystic ovary syndrome and significantly reduced during pioglitazone treatment. Diabetes Care 2008; 31: 328-334.
    • (2008) Diabetes Care , vol.31 , pp. 328-334
    • Glintborg, D.1    Hojlund, K.2    Andersen, M.3    Henriksen, J.E.4    Beck-Nielsen, H.5    Handberg, A.6
  • 28
    • 77953616456 scopus 로고    scopus 로고
    • Relation of C-reactive protein to abdominal adiposity
    • Brooks GC, Blaha MJ, Blumenthal RS. Relation of C-reactive protein to abdominal adiposity. Am J Cardiol 2010; 106: 56-61.
    • (2010) Am J Cardiol , vol.106 , pp. 56-61
    • Brooks, G.C.1    Blaha, M.J.2    Blumenthal, R.S.3
  • 29
    • 71949101822 scopus 로고    scopus 로고
    • YKL-40-an emerging biomarker in cardiovascular disease and diabetes
    • Rathcke CN, Vestergaard H. YKL-40-an emerging biomarker in cardiovascular disease and diabetes. Cardiovasc Diabetol 2009; 8: 61.
    • (2009) Cardiovasc Diabetol , vol.8 , pp. 61
    • Rathcke, C.N.1    Vestergaard, H.2
  • 31
    • 61549094077 scopus 로고    scopus 로고
    • Weight and type 2 diabetes after bariatric surgery: Systematic review and meta-analysis
    • Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories WJ et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 2009; 122: 248-256.e5.
    • (2009) Am J Med , vol.122
    • Buchwald, H.1    Estok, R.2    Fahrbach, K.3    Banel, D.4    Jensen, M.D.5    Pories, W.J.6
  • 32
    • 79960088798 scopus 로고    scopus 로고
    • Changes in glucose homeostasis after Roux-en-Y gastric bypass surgery for obesity at day three, two months, and one year after surgery: Role of gut peptides
    • Falken Y, Hellstrom PM, Holst JJ, Naslund E. Changes in glucose homeostasis after Roux-en-Y gastric bypass surgery for obesity at day three, two months, and one year after surgery: role of gut peptides. J Clin Endocrinol Metab 2011; 96: 2227-2235.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 2227-2235
    • Falken, Y.1    Hellstrom, P.M.2    Holst, J.J.3    Naslund, E.4
  • 34
    • 85027956925 scopus 로고    scopus 로고
    • Triglycerides and cardiovascular disease: A scientific statement from the American Heart Association
    • Miller M, Stone NJ, Ballantyne C, Bittner V, Criqui MH, Ginsberg HN et al. Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 2011; 123: 2292-2333.
    • (2011) Circulation , vol.123 , pp. 2292-2333
    • Miller, M.1    Stone, N.J.2    Ballantyne, C.3    Bittner, V.4    Criqui, M.H.5    Ginsberg, H.N.6
  • 35
    • 77951642621 scopus 로고    scopus 로고
    • Soluble CD36 (sCD36) clusters with markers of insulin resistance, and high sCD36 is associated with increased type 2 diabetes risk
    • Handberg A, Norberg M, Stenlund H, Hallmans G, Attermann J, Eriksson JW. Soluble CD36 (sCD36) clusters with markers of insulin resistance, and high sCD36 is associated with increased type 2 diabetes risk. J Clin Endocrinol Metab 2010; 95: 1939-1946.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1939-1946
    • Handberg, A.1    Norberg, M.2    Stenlund, H.3    Hallmans, G.4    Attermann, J.5    Eriksson, J.W.6
  • 36
    • 84884594181 scopus 로고    scopus 로고
    • Impact of obesity and insulin-resistance on cirrhosis and portal hypertension
    • Berzigotti A, Abraldes JG. Impact of obesity and insulin-resistance on cirrhosis and portal hypertension. Gastroenterol Hepatol 2013; 36: 527-533.
    • (2013) Gastroenterol Hepatol , vol.36 , pp. 527-533
    • Berzigotti, A.1    Abraldes, J.G.2
  • 37
    • 84865422248 scopus 로고    scopus 로고
    • From excess adiposity to insulin resistance: The role of free fatty acids
    • Capurso C, Capurso A. From excess adiposity to insulin resistance: the role of free fatty acids. Vascul Pharmacol 2012; 57: 91-97.
    • (2012) Vascul Pharmacol , vol.57 , pp. 91-97
    • Capurso, C.1    Capurso, A.2
  • 38
    • 33749349147 scopus 로고    scopus 로고
    • CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine
    • Nauli AM, Nassir F, Zheng S, Yang Q, Lo CM, Vonlehmden SB et al. CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine. Gastroenterology 2006; 131: 1197-1207.
    • (2006) Gastroenterology , vol.131 , pp. 1197-1207
    • Nauli, A.M.1    Nassir, F.2    Zheng, S.3    Yang, Q.4    Lo, C.M.5    Vonlehmden, S.B.6
  • 39
    • 85047690709 scopus 로고    scopus 로고
    • Increased CD36 protein as a response to defective insulin signaling in macrophages
    • Liang CP, Han S, Okamoto H, Carnemolla R, Tabas I, Accili D et al. Increased CD36 protein as a response to defective insulin signaling in macrophages. J Clin Invest 2004; 113: 764-773.
    • (2004) J Clin Invest , vol.113 , pp. 764-773
    • Liang, C.P.1    Han, S.2    Okamoto, H.3    Carnemolla, R.4    Tabas, I.5    Accili, D.6
  • 42
    • 84859942552 scopus 로고    scopus 로고
    • Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease
    • Lomonaco R, Ortiz-Lopez C, Orsak B, Webb A, Hardies J, Darland C et al. Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease. Hepatology 2012; 55: 1389-1397.
    • (2012) Hepatology , vol.55 , pp. 1389-1397
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3    Webb, A.4    Hardies, J.5    Darland, C.6
  • 43
    • 77952563455 scopus 로고    scopus 로고
    • Liver fat in the pathogenesis of insulin resistance and type 2 diabetes
    • Yki-Jarvinen H. Liver fat in the pathogenesis of insulin resistance and type 2 diabetes. Dig Dis 2010; 28: 203-209.
    • (2010) Dig Dis , vol.28 , pp. 203-209
    • Yki-Jarvinen, H.1
  • 44
    • 80052596785 scopus 로고    scopus 로고
    • Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C
    • Miquilena-Colina ME, Lima-Cabello E, Sanchez-Campos S, Garcia-Mediavilla MV, Fernandez-Bermejo M, Lozano-Rodriguez T et al. Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C. Gut 2011; 60: 1394-1402.
    • (2011) Gut , vol.60 , pp. 1394-1402
    • Miquilena-Colina, M.E.1    Lima-Cabello, E.2    Sanchez-Campos, S.3    Garcia-Mediavilla, M.V.4    Fernandez-Bermejo, M.5    Lozano-Rodriguez, T.6
  • 45
    • 55749104215 scopus 로고    scopus 로고
    • Soluble CD36 in plasma is increased in patients with symptomatic atherosclerotic carotid plaques and is related to plaque instability
    • Handberg A, Skjelland M, Michelsen AE, Sagen EL, Krohg-Sorensen K, Russell D et al. Soluble CD36 in plasma is increased in patients with symptomatic atherosclerotic carotid plaques and is related to plaque instability. Stroke 2008; 39: 3092-3095.
    • (2008) Stroke , vol.39 , pp. 3092-3095
    • Handberg, A.1    Skjelland, M.2    Michelsen, A.E.3    Sagen, E.L.4    Krohg-Sorensen, K.5    Russell, D.6
  • 46
    • 33645815907 scopus 로고    scopus 로고
    • YKL-40 a biomarker of inflammation, is elevated in patients with type 2 diabetes and is related to insulin resistance
    • Rathcke CN, Johansen JS, Vestergaard H. YKL-40 a biomarker of inflammation, is elevated in patients with type 2 diabetes and is related to insulin resistance. Inflamm Res 2006; 55: 53-59.
    • (2006) Inflamm Res , vol.55 , pp. 53-59
    • Rathcke, C.N.1    Johansen, J.S.2    Vestergaard, H.3
  • 48
    • 78650917241 scopus 로고    scopus 로고
    • Increased circulating and visceral adipose tissue expression levels of YKL-40 in obesity-associated type 2 diabetes are related to inflammation: Impact of conventional weight loss and gastric bypass
    • Catalan V, Gomez-Ambrosi J, Rodriguez A, Ramirez B, Rotellar F, Valenti V et al. Increased circulating and visceral adipose tissue expression levels of YKL-40 in obesity-associated type 2 diabetes are related to inflammation: impact of conventional weight loss and gastric bypass. J Clin Endocrinol Metab 2011; 96: 200-209.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 200-209
    • Catalan, V.1    Gomez-Ambrosi, J.2    Rodriguez, A.3    Ramirez, B.4    Rotellar, F.5    Valenti, V.6


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