Clinical comparisons of two free light chain assays to immunofixation electrophoresis for detecting monoclonal gammopathy

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Kim, Han Sung ^a   Kim, Hyun Soo ^a   Shin, Kyu Sung ^a   Song, Wonkeun ^a   Kim, Hyo Jung ^a   Kim, Hyeong Su ^a   Park, Min Jeong ^a  

^a Hallym University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FREE LIGHT CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; BLOOD SAMPLING; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; DOUBLE BLIND PROCEDURE; ELECTROPHORESIS; FEMALE; FREELITE FLC ASSAY; HUMAN; IMMUNOASSAY; IMMUNOFIXATION ELECTROPHORESIS; IMMUNOLOGY TEST KIT; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MOLECULAR DIAGNOSTICS; MONOCLONAL IMMUNOGLOBULINEMIA; N LATEX FLC ASSAY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; URINALYSIS; AGED; BLOOD; COMPARATIVE STUDY; IMMUNOLOGY; PARAPROTEINEMIAS; PROCEDURES;

AGED; ELECTROPHORESIS; FEMALE; HUMANS; IMMUNOASSAY; IMMUNOGLOBULIN LIGHT CHAINS; MALE; PARAPROTEINEMIAS;

EID: 84902247344     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/647238     Document Type: Article

References (12)

1. Davids M. S., Murali M. R., Kuter D. J., Serum free light chain analysis. The American Journal of Hematology 2010 85 10 787 790 2-s2.0-77957660997 10.1002/ajh.21815
2. Jung S., Kim M., Lim J., Kim Y., Han K., Min C.-K., Min W.-S., Serum free light chains for diagnosis and follow-up of multiple myeloma. Korean Journal of Laboratory Medicine 2008 28 3 169 173 2-s2.0-60749120415 10.3343/kjlm.2008.28. 3.169
3. Briand P.-Y., Decaux O., Caillon H., Grosbois B., Le Treut A., Guenet L., Analytical performance of the serum free light chain assay. Clinical Chemistry and Laboratory Medicine 2010 48 1 73 79 2-s2.0-74549176580 10.1515/CCLM.2010.012
4. Dispenzieri A., Kyle R., Merlini G., Miguel J. S., Ludwig H., Hajek R., Palumbo A., Jagannath S., Blade J., Lonial S., Dimopoulos M., Comenzo R., Einsele H., Barlogie B., Anderson K., Gertz M., Harousseau J. L., Attal M., Tosi P., Sonneveld P., Boccadoro M., Morgan G., Richardson P., Sezer O., Mateos M. V., Cavo M., Joshua D., Turesson I., Chen W., Shimizu K., Powles R., Rajkumar S. V., Durie B. G. M., International myeloma working group guidelines for serum-free light chain analysis in multiple myeloma and related disorders. Leukemia 2009 23 2 215 224 2-s2.0-60149096306 10.1038/leu.2008.307
5. Tate J., Bazeley S., Sykes S., Mollee P., Quantitative serum free light chain assay-analytical issues. Clinical Biochemist Reviews 2009 30 3 131 140
6. Jacobs J. F. M., Hoedemakers R. M. J., Teunissen E., van der Molen R. G., te Velthuis H., Effect of sample dilution on two free light chain nephelometric assays. Clinica Chimica Acta 2012 413 19-20 1708 1709 2-s2.0-84864380618 10.1016/j.cca.2012.04.032
7. Bosmann M., Kößler J., Stolz H., Walter U., Knop S., Steigerwald U., Detection of serum free light chains: the problem with antigen excess. Clinical Chemistry and Laboratory Medicine 2010 48 10 1419 1422 2-s2.0-77958190515 10.1515/CCLM.2010.283
8. Vercammen M., Meirlaen P., Broodtaerts L., Broek I. V., Bossuyt X., Effect of sample dilution on serum free light chain concentration by immunonephelometric assay. Clinica Chimica Acta 2011 412 19-20 1798 1804 2-s2.0-79960619104 10.1016/j.cca.2011.06.021
9. te Velthuis H., Knop I., Stam P., van den Broek M., Bos H. K., Hol S., Teunissen E., Fischedick K. S., Althaus H., Schmidt B., Wagner C., Melsert R., N Latex FLC-new monoclonal high-performance assays for the determination of free light chain kappa and lambda. Clinical Chemistry and Laboratory Medicine 2011 49 8 1323 1332 2-s2.0-80051727075 10.1515/CCLM.2011.624
10. Hoedemakers R. M. J., Pruijt J. F. M., Hol S., Teunissen E., Martens H., Stam P., Melsert R., Te Velthuis H., Clinical comparison of new monoclonal antibody-based nephelometric assays for free light chain kappa and lambda to polyclonal antibody-based assays and immunofixation electrophoresis. Clinical Chemistry and Laboratory Medicine 2012 50 3 489 495 2-s2.0-84860478665 10.1515/cclm.2011.793
11. Drayson M., Carr-Smith H., Clinical comparison of new monoclonal antibody-based nephelometric assays for free light chain and to polyclonal antibody-based assays and immunofixation electrophoresis. Clinical Chemistry and Laboratory Medicine 2012 50 3 587 588 2-s2.0-84860456002 10.1515/cclm-2012-0037
12. Jaskowski T. D., Litwin C. M., Hill H. R., Detection of and light chain monoclonal proteins in human serum: automated immunoassay versus immunofixation electrophoresis. Clinical and Vaccine Immunology 2006 13 2 277 280 2-s2.0-33644923216 10.1128/CVI.13.2.277-280.2006.