Clinical comparison of new monoclonal antibody-based nephelometric assays for free light chain κ and λ to polyclonal antibody-based assays and immunofixation electrophoresis

Clinical Chemistry and Laboratory Medicine

Volumn 50, Issue 3, 2012, Pages 587-588

  Drayson, Mark ^a   Carr Smith, Hugh ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b Binding Site Group Ltd   (United Kingdom)

Author keywords

immunoassay; method comparison; monoclonal

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY;

AMYLOIDOSIS; ELECTROPHORESIS; GENETIC RECOMBINATION; GENETIC VARIABILITY; HUMAN; IMMUNOASSAY; IMMUNOFIXATION ELECTROPHORESIS; INTERMETHOD COMPARISON; LETTER; LIGHT CHAIN; MONOCLONAL IMMUNOGLOBULINEMIA; MULTIPLE MYELOMA; NEPHELOMETRY; PLASMACYTOMA; PRIORITY JOURNAL; SCREENING TEST; SOMATIC HYPERMUTATION;

ANTIBODIES, MONOCLONAL; ELECTROPHORESIS; HUMANS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; NEPHELOMETRY AND TURBIDIMETRY; SEROLOGIC TESTS;

EID: 84860456002     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2012-0037     Document Type: Letter

References (2)

1. Hoedemakers RM, Pruijt JF, Hol S, Teunissen E, Martens H, Stam P, et al. Clinical comparison of new monoclonal antibody- based nephelometric assays for free light chain kappa and lambda to polyclonal antibody-based assays and immunofi xation electrophoresis. Clin Chem Lab Med 2012;50: 489-95.
2. Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R, et al. On behalf of the International Myeloma Working Group. International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders. Leukemia 2008;