Organophosphate-pyrethroid combination pesticides may be associated with increased toxicity in human poisoning compared to either pesticide alone

Clinical Toxicology

Volumn 52, Issue 5, 2014, Pages 538-541

  Iyyadurai, R ^a   Peter, J V ^a   Immanuel, S ^a   Begum, A ^a   Zachariah, A ^a   Jasmine, S ^a   Abhilash, K P P ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Combination; Insecticides; Organophosphorus; Outcome; Pyrethroid

Indexed keywords

CHLORPYRIFOS; CYPERMETHRIN; ORGANOPHOSPHATE; PYRETHROID;

ADOLESCENT; ADULT; CONFERENCE PAPER; DETOXIFICATION; FEMALE; HOSPITALIZATION; HUMAN; INTOXICATION; MAJOR CLINICAL STUDY; MALE; SEIZURE;

COMBINATION; INSECTICIDES; ORGANOPHOSPHORUS; OUTCOME; PYRETHROID;

ADOLESCENT; ADULT; CHLORPYRIFOS; FEMALE; HOSPITALIZATION; HUMANS; LENGTH OF STAY; MALE; ORGANOPHOSPHATE POISONING; PESTICIDES; PROSPECTIVE STUDIES; PYRETHRINS; RESPIRATION, ARTIFICIAL; SEIZURES; YOUNG ADULT;

EID: 84902245165     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2014.909933     Document Type: Conference Paper

References (10)

1. Martin T, Ochou O G, Vaissayre M, Fournier D. Organophosphorus insecticides synergize pyrethroids in the resistant strain of cotton bollworm, Helicoverpa armigera (H ü bner) (Lepidoptera: Noctuidae) from West Africa. J Econ Entomol 2003;96:468-474.
2. Tripathi M, Pandey R, Ambesh S P, Pandey M. A mixture of organophosphate and pyrethroid intoxication requiring intensive care unit admission: a diagnostic dilemma and therapeutic approach. Anaesth Analg 2006;103:410-412.
3. Peter JV, Jerobin J, Nair A, Bennett A, Samuel P, Chrispal A, et al. Clinical profile and outcome of patients hospitalized with dimethyl and diethyl organophosphate poisoning. Clin Toxicol (Phila) 2010;48:916-923.
4. Bradberry SM, Cage SA, Proudfoot AT, Vale JA. Poisoning due to pyrethroids. Toxicol Rev 2005;24:93-106.
5. Hernandez AF, Parron T, Tsatsakis AM, Requena M, Alarcon R, Lopez-Guarnido O. Toxic effects of pesticide mixtures at a molecular level: their relevance to human health. Toxicology 2013;307:136-145.
6. Schoenfeld DA, Bernard GR. Statistical evaluation of ventilatorfree days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome. Crit Care Med 2002;30:1772-1777.
7. Peter JV, Jerobin J, Nair A, Bennett A. Is there a relationship between the WHO hazard classification of organophosphate pesticide and outcomes in suicidal human poisoning with commercial organophosphate formulations? Regul Toxicol Pharmacol 2010;57:99-102.
8. Eddleston M, Mohamed F, Davies JO, Eyer P, Worek F, Sheriff MH, Buckley NA. Respiratory failure in acute organophosphate pesticide self-poisoning. QJM 2006;99:513-522.
9. Eddleston M, Eyer P, Worek F, Mohamed F, Senarathna L, von Meyer L, et al. Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study. Lancet 2005;366:1452-1459.
10. He F, Chen S, Tang X, Gan W, Tao B, Wen B. Biological monitoring of combined exposure to organophosphates and pyrethroids. Toxicol Lett 2002;134:119-124.