Effects of cannabis on cognition in patients with MS: A psychometric and MRI study

Neurology

Volumn 82, Issue 21, 2014, Pages 1879-1887

  Pavisian, Bennis ^a   MacIntosh, Bradley J ^a   Szilagyi, Greg ^a   Staines, Richard W ^a   O'Connor, Paul ^a,b   Feinstein, Anthony ^a,b  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABIS; DRONABINOL;

10/36 SPATIAL RECALL TEST; ADULT; ANTERIOR CINGULATE; ARTICLE; ATTENTION; BRAIN ATROPHY; BRAIN NUCLEUS; BRAIN TISSUE; CANNABIS SMOKING; CEREBELLUM; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONSTRUCT VALIDITY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CUNEUS; DIFFUSION TENSOR IMAGING; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INFERIOR PARIETAL LOBULE; INFERIOR TEMPORAL GYRUS; LEFT HEMISPHERE; LENTIFORM NUCLEUS; LINGUAL GYRUS; MALE; MIDDLE FRONTAL GYRUS; MULTIPLE SCLEROSIS; NEUROIMAGING; NEUROPATHOLOGY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE SCANNER; OCCIPITAL GYRUS; PACED AUDITORY SERIAL ADDITION TEST; PARAHIPPOCAMPAL GYRUS; POSTCENTRAL GYRUS; PRECUNEUS; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; RECALL; RESTING STATE NETWORK; RIGHT HEMISPHERE; SELECTIVE REMINDING TEST REVISED; SUPERIOR FRONTAL GYRUS; SUPERIOR TEMPORAL GYRUS; SYMBOL DIGIT MODALITIES TEST; TASK PERFORMANCE; VISUAL MEMORY; WORKING MEMORY;

ADOLESCENT; ADULT; BRAIN; BRAIN MAPPING; COGNITION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MARIJUANA SMOKING; MIDDLE AGED; MULTIPLE SCLEROSIS; PSYCHOMETRICS; YOUNG ADULT;

EID: 84902201152     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000000446     Document Type: Article

References (36)

1. Rao SM, Leo GJ, Bernardin L, Unverzagt F. Cognitive dysfunction in multiple sclerosis: I: frequency, patterns, and prediction. Neurology 1991;41:685-691.
2. Ghaffar O, Feinstein A. Multiple sclerosis and cannabis: a cognitive and psychiatric study. Neurology 2008;71: 164-169.
3. Honarmand K, Tierney MC, O'Connor P, Feinstein A. Effects of cannabis on cognitive function in patients with multiple sclerosis. Neurology 2011;76:1153-1160.
4. Rao SM, Leo GJ, Ellington L, Nauertz T, Bernardin L, Unverzagt F. Cognitive dysfunction in multiple sclerosis: II: impact on employment and social functioning. Neurology 1991;41:692-696.
5. Filippi M, Rocca MA, Benedict RHB, et al. The contribution of MRI in assessing cognitive impairment in multiple sclerosis. Neurology 2010;75:2121-2128.
6. Sumowski J, Wylie G, DeLuca J, Chiaravalloti N. Intellectual enrichment is linked to cerebral efficiency in multiple sclerosis: functional magnetic resonance imaging evidence for cognitive reserve. Brain 2010;133:362-374.
7. Sweet L, Rao S, Primeau M, Mayer A, Cohen R. Functional magnetic resonance imaging of working memory among multiple sclerosis patients. J Neuroimaging 2004; 14:150-157.
8. Wishart HA, Saykin AJ, McDonald BC, et al. Brain activation patterns associated with working memory in relapsing-remitting MS. Neurology 2004;62:234-238.
9. Owen AM, McMillan KM, Laird AR, Bullmore E. N-Back working memory paradigm: a meta analysis of normative functional neuroimaging studies. Hum Brain Mapp 2005;25:46-59.
10. Allsop DJ, Norberg MM, Copeland J, Fu S, Budney AJ. The Cannabis Withdrawal Scale development: patterns and predictors of cannabis withdrawal and distress. Drug Alcohol Depend 2011;119:123-129.
11. Rao SM. A Manual for the Brief, Repeatable Battery of Neuropsychological Tests in Multiple Sclerosis. New York: National Multiple Sclerosis Society; 1990:121-123.
12. Tiffin J, Asher EJ. The Purdue Pegboard: norms and studies of reliability and validity. J Appl Psychol 1948;32:234-247.
13. Wechsler D. Wechsler Test of Adult Reading: WTAR. San Antonio: Psychological Corporation; 2001.
14. Honarmand K, Feinstein A. Validation of the Hospital Anxiety and Depression Scale for use with multiple sclerosis patients. Mult Scler 2009;15:1518-1524.
15. Fisk JD, Ritvo PG, Ross L, Haase DA, Marrie TJ, Schlech WF. Measuring the functional impact of fatigue: initial validation of the Fatigue Impact Scale. Clin Infect Dis 1994;18(suppl 1):S79-S83.
16. Baddeley A. Working memory: looking back and looking forward. Nat Rev Neurosci 2003;4:829-839.
17. Martin-Santos R, Fagundo AB, Crippa JA, et al. Neuroimaging in cannabis: a systematic review. Psychol Med 2010;40:383-398.
18. Bonavita S, Gallo A, Sacco R, et al. Distributed changes in default-mode resting-state connectivity in multiple sclerosis. Mult Scler 2011;17:411-422.
19. Solowij N, Stephens RS, Roffman RA, et al. Cognitive functioning of long-term heavy cannabis users seeking treatment. JAMA 2002;287:1123-1131.
20. Crean RD, Crane NA, Mason BJ. An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. J Addict Med 2011;5: 1-8.
21. Tunving K. Psychiatric effects of cannabis use. Acta Psychiatr Scand 1985;72:209-217.
22. Mathew RJ, Wilson WH, Tant SR. Acute changes in cerebral blood flow associated with marijuana smoking. Acta Psychiatr Scand 1989;79:118-128.
23. Rocca MA, Valsasina P, Absinta M, et al. Default-mode network dysfunction and cognitive impairment in progressive MS. Neurology 2010;74:1252-1259.
24. Sneider JT, Pope HG Jr, Silveri MM, Simpson NS, Gruber SA, Yurgelun-Todd DA. Differences in regional blood volume during a 28 day abstinence in chronic cannabis smokers. Eur Neuropsychopharmacol 2008;18:612-619.
25. Mathew RJ, Tant S, Burger C. Regional cerebral blood flow in marijuana smokers. Br J Addict 1986;81:567-571.
26. Sevy S, Smith GS, Ma Y, et al. Cerebral glucose metabolism and D2/D3 receptor availability in young adults with cannabis dependence measured with positron emission tomography. Psychopharmacology 2008;197:549-556.
27. Tunving K, Thulin SO, Risberg J, Warkentin S. Regional cerebral blood flow in long-term heavy cannabis use. Pyschiatry Res 1986;17:15-21.
28. Lundqvist T, Jönsson S, Warkentin S. Frontal lobe dysfunction in long-term cannabis users. Neurotoxicol Teratol 2001;23:437-443.
29. Block RI, O'Leary D, Hichwa RD, et al. Cerebellar hypoactivity in frequent marijuana users. Neuroreport 2000;11: 749-753.
30. Crottaz-Herbette S, Anagnoson RT, Menon V. Modality effects in verbal working memory: differential prefrontal and parietal responses to auditory and visual stimuli. Neuroimage 2004;21:340-351.
31. Sweet LH, Rao SM, Primeau M, Durgerian S, Cohen RA. Functional magnetic resonance imaging response to increased verbal working memory demands among patients with multiple sclerosis. Hum Brain Mapp 2006;27:28-36.
32. Jager G, Van Hell HH, De Win MM, et al. Effects of frequent cannabis use on hippocampal activity during an associative memory task. Eur Neuropsychopharmacol 2007;17: 289-297.
33. Jacobsen LK, Mencl WE, Westerveld M, Pudge KR. Impact of cannabis use on brain function in adolescents. Ann NY Acad Sci 2004;1021:384-390.
34. Smith AM, Longo CA, Fried PA, Hogan MJ, Cameron I. Effects of marijuana on visuospatial working memory: an fMRI study in young adults. Psychopharmacology 2010; 210:429-438.
35. Becker B, Wagner D, Gouzoulis-Mayfrank E, Spuentrup E, Daumann J. The impact of early-onset cannabis use on functional brain correlates of working memory. Prog Neuropsychopharmacol Biol Psychiatry 2010;34:837-845.
36. Nestor L, Roberts G, Garavan H, Hester R. Deficits in learning and memory: parahippocampal hyperactivity and frontocortical hypoactivity in cannabis users. Neuroimage 2008;40:1328-1339.