-
1
-
-
84859827825
-
Recent advances in the molecular pathogenesis and targeted therapies of medullary thyroid carcinoma
-
1. Almeida MQ, Hoff AO 2012 Recent advances in the molecular pathogenesis and targeted therapies of medullary thyroid carcinoma. Curr Opin Oncol 24:229-234.
-
(2012)
Curr Opin Oncol
, vol.24
, pp. 229-234
-
-
Almeida, M.Q.1
Hoff, A.O.2
-
2
-
-
73149115248
-
Targeting the RET pathway in thyroid cancer
-
Wells SA Jr, Santoro M 2009 Targeting the RET pathway in thyroid cancer. Clin Cancer Res 15:7119-7123.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7119-7123
-
-
Wells Jr., S.A.1
Santoro, M.2
-
3
-
-
79955669404
-
High prevalence of RAS mutations in RET-negative sporadic medullary thyroid carcinomas
-
Moura MM, Cavaco BM, Pinto AE, Leite V 2011 High prevalence of RAS mutations in RET-negative sporadic medullary thyroid carcinomas. J Clin Endocrinol Metab 96:E863-E868.
-
(2011)
J Clin Endocrinol Metab
, vol.96
-
-
Moura, M.M.1
Cavaco, B.M.2
Pinto, A.E.3
Leite, V.4
-
4
-
-
84867239036
-
Somatic RAS mutations occur in a large proportion of sporadic RET-negative medullary thyroid carcinomas and extend to a previously unidentified exon
-
Boichard A, Croux L, Al GA, Broutin S, Dupuy C, Leboulleux S, Schlumberger M, Bidart JM, Lacroix L 2012 Somatic RAS mutations occur in a large proportion of sporadic RET-negative medullary thyroid carcinomas and extend to a previously unidentified exon. J Clin Endocrinol Metab 97:E2031-E2035.
-
(2012)
J Clin Endocrinol Metab
, vol.97
-
-
Boichard, A.1
Croux, L.2
Al, G.A.3
Broutin, S.4
Dupuy, C.5
Leboulleux, S.6
Schlumberger, M.7
Bidart, J.M.8
Lacroix, L.9
-
5
-
-
84655175698
-
Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: A randomized, double-blind phase III trial
-
Wells SA Jr, Robinson BG, Gagel RF, Dralle H, Fagin JA, Santoro M, Baudin E, Elisei R, Jarzab B, Vasselli JR, Read J, Langmuir P, Ryan AJ, Schlumberger MJ 2012 Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: A randomized, double-blind phase III trial. J Clin Oncol 30:134-141.
-
(2012)
J Clin Oncol
, vol.30
, pp. 134-141
-
-
Wells Jr., S.A.1
Robinson, B.G.2
Gagel, R.F.3
Dralle, H.4
Fagin, J.A.5
Santoro, M.6
Baudin, E.7
Elisei, R.8
Jarzab, B.9
Vasselli, J.R.10
Read, J.11
Langmuir, P.12
Ryan, A.J.13
Schlumberger, M.J.14
-
6
-
-
84867754481
-
An international, double-blind, randomized, placebo-controlled Phase III trial (EXAM) of cabozantinib (XL184) in medullary thyroid carcinoma (MTC) patients (pts) with documented RECIST progression at baseline
-
abstract
-
Schoffski P, Elisei R, Muller S, et al. 2012 An international, double-blind, randomized, placebo-controlled Phase III trial (EXAM) of cabozantinib (XL184) in medullary thyroid carcinoma (MTC) patients (pts) with documented RECIST progression at baseline. J Clin Oncol 30: Suppl:5508. abstract.
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
, pp. 5508
-
-
Schoffski, P.1
Elisei, R.2
Muller, S.3
-
7
-
-
77952468875
-
Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer
-
Lam ET, Ringel MD, Kloos RT, Prior TW, Knopp MV, Liang J, Sammet S, Hall NC, Wakely PE Jr, Vasko VV, Saji M, Snyder PJ, Wei L, Arbogast D, Collamore M, Wright JJ, Moley JF, Villalona-Calero MA, Shah MH 2010 Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer. J Clin Oncol 28:2323-2330.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2323-2330
-
-
Lam, E.T.1
Ringel, M.D.2
Kloos, R.T.3
Prior, T.W.4
Knopp, M.V.5
Liang, J.6
Sammet, S.7
Hall, N.C.8
Wakely Jr., P.E.9
Vasko, V.V.10
Saji, M.11
Snyder, P.J.12
Wei, L.13
Arbogast, D.14
Collamore, M.15
Wright, J.J.16
Moley, J.F.17
Villalona-Calero, M.A.18
Shah, M.H.19
-
8
-
-
0029650769
-
Cushing's syndrome
-
Orth DN 1995 Cushing's syndrome. N Engl J Med 332:791-803.
-
(1995)
N Engl J Med
, vol.332
, pp. 791-803
-
-
Orth, D.N.1
-
9
-
-
69949084562
-
Approach to the patient with possible Cushing's syndrome
-
Boscaro M, Arnaldi G 2009 Approach to the patient with possible Cushing's syndrome. J Clin Endocrinol Metab 94:3121-3131.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 3121-3131
-
-
Boscaro, M.1
Arnaldi, G.2
-
10
-
-
22244486665
-
Ectopic adrenocorticotropic hormone-syndrome in medullary carcinoma of the thyroid: A retrospective analysis and review of the literature
-
DOI 10.1089/thy.2005.15.618
-
Barbosa SL, Rodien P, Leboulleux S, Niccoli-Sire P, Kraimps JL, Caron P, Archambeaud-Mouveroux F, Conte-Devolx B, Rohmer V 2005 Ectopic adrenocorticotropic hormone-syndrome in medullary carcinoma of the thyroid: A retrospective analysis and review of the literature. Thyroid 15:618-623. (Pubitemid 40993738)
-
(2005)
Thyroid
, vol.15
, Issue.6
, pp. 618-623
-
-
Barbosa, S.L.-S.1
Podien, P.2
Leboulleux, S.3
Niccoli-Sire, P.4
Kraimps, J.-L.5
Caron, P.6
Archambeaud-Mouveroux, F.7
Conte-Devolx, B.8
Rohmer, V.9
-
11
-
-
84055217296
-
EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas
-
Fukuoka H, Cooper O, Ben-Shlomo A, Mamelak A, Ren SG, Bruyette D, Melmed S 2011 EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas. J Clin Invest 121:4712-4721.
-
(2011)
J Clin Invest
, vol.121
, pp. 4712-4721
-
-
Fukuoka, H.1
Cooper, O.2
Ben-Shlomo, A.3
Mamelak, A.4
Ren, S.G.5
Bruyette, D.6
Melmed, S.7
-
12
-
-
79957666660
-
GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary
-
Carbajal L, Biswas A, Niswander LM, Prizant H, Hammes SR 2011 GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary. Mol Endocrinol 25:1055-1065.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1055-1065
-
-
Carbajal, L.1
Biswas, A.2
Niswander, L.M.3
Prizant, H.4
Hammes, S.R.5
-
13
-
-
32944474182
-
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
-
Kamba T, Tam BY, Hashizume H, Haskell A, Sennino B, Mancuso MR, Norberg SM, O'Brien SM, Davis RB, Gowen LC, Anderson KD, Thurston G, Joho S, Springer ML, Kuo CJ, McDonald DM 2006 VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 290:H560-H576.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Kamba, T.1
Tam, B.Y.2
Hashizume, H.3
Haskell, A.4
Sennino, B.5
Mancuso, M.R.6
Norberg, S.M.7
O'Brien, S.M.8
Davis, R.B.9
Gowen, L.C.10
Anderson, K.D.11
Thurston, G.12
Joho, S.13
Springer, M.L.14
Kuo, C.J.15
McDonald, D.M.16
-
14
-
-
67649246190
-
Nonclinical safety evaluation of sunitinib: A potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors
-
Patyna S, Arrigoni C, Terron A, Kim TW, Heward JK, Vonderfecht SL, Denlinger R, Turnquist SE, Evering W 2008 Nonclinical safety evaluation of sunitinib: A potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors. Toxicol Pathol 36:905-916.
-
(2008)
Toxicol Pathol
, vol.36
, pp. 905-916
-
-
Patyna, S.1
Arrigoni, C.2
Terron, A.3
Kim, T.W.4
Heward, J.K.5
Vonderfecht, S.L.6
Denlinger, R.7
Turnquist, S.E.8
Evering, W.9
-
15
-
-
33846440150
-
Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma
-
DOI 10.1634/theoncologist.12-1-107
-
Rock EP, Goodman V, Jiang JX, Mahjoob K, Verbois SL, Morse D, Dagher R, Justice R, Pazdur R 2007 Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma. Oncologist 12: 107-113. (Pubitemid 46143508)
-
(2007)
Oncologist
, vol.12
, Issue.1
, pp. 107-113
-
-
Rock, E.P.1
Goodman, V.2
Jiang, J.X.3
Mahjoob, K.4
Verbois, S.L.5
Morse, D.6
Dagher, R.7
Justice, R.8
Pazdur, R.9
-
16
-
-
84876223032
-
Kinase inhibitors: Adverse effects related to the endocrine system
-
Lodish MB 2013 Kinase inhibitors: Adverse effects related to the endocrine system. J Clin Endocrinol Metab 98:1333-1342.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 1333-1342
-
-
Lodish, M.B.1
-
17
-
-
84873650357
-
Tyrosine kinase inhibitor-induced thyroid disorders: A review and hypothesis
-
Makita N, Iiri T 2013 Tyrosine kinase inhibitor-induced thyroid disorders: A review and hypothesis. Thyroid 23:151-159.
-
(2013)
Thyroid
, vol.23
, pp. 151-159
-
-
Makita, N.1
Iiri, T.2
-
18
-
-
84881228422
-
Reversal of Cushing's syndrome by vandetanib in medullary thyroid carcinoma
-
Baudry C, Paepegaey AC, Groussin L 2013 Reversal of Cushing's syndrome by vandetanib in medullary thyroid carcinoma. N Engl J Med 369:584-586.
-
(2013)
N Engl J Med
, vol.369
, pp. 584-586
-
-
Baudry, C.1
Paepegaey, A.C.2
Groussin, L.3
-
19
-
-
84881256059
-
Vandetanib in children and adolescents with multiple endocrine neoplasia type 2B associated medullary thyroid carcinoma
-
Fox E, Widemann BC, Chuk MK, Marcus L, Aikin A, Whitcomb PO, Merino MJ, Lodish M, Dombi E, Steinberg SM, Wells SA, Balis FM 2013 Vandetanib in children and adolescents with multiple endocrine neoplasia type 2B associated medullary thyroid carcinoma. Clin Cancer Res 19:4239-4248.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4239-4248
-
-
Fox, E.1
Widemann, B.C.2
Chuk, M.K.3
Marcus, L.4
Aikin, A.5
Whitcomb, P.O.6
Merino, M.J.7
Lodish, M.8
Dombi, E.9
Steinberg, S.M.10
Wells, S.A.11
Balis, F.M.12
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